134 research outputs found
Scaling laws for random walks in long-range correlated disordered media
We study the scaling laws of diffusion in two-dimensional media with
long-range correlated disorder through exact enumeration of random walks. The
disordered medium is modelled by percolation clusters with correlations
decaying with the distance as a power law, , generated with the
improved Fourier filtering method. To characterize this type of disorder, we
determine the percolation threshold by investigating
cluster-wrapping probabilities. At , we estimate the
(sub-diffusive) walk dimension for different correlation
exponents . Above , our results suggest a normal random walk
behavior for weak correlations, whereas anomalous diffusion cannot be ruled out
in the strongly correlated case, i.e., for small .Comment: 11 pages, 6 figure
Percolation thresholds and fractal dimensions for square and cubic lattices with long-range correlated defects
We study long-range power-law correlated disorder on square and cubic
lattices. In particular, we present high-precision results for the percolation
thresholds and the fractal dimension of the largest clusters as function of the
correlation strength. The correlations are generated using a discrete version
of the Fourier filtering method. We consider two different metrics to set the
length scales over which the correlations decay, showing that the percolation
thresholds are highly sensitive to such system details. By contrast, we verify
that the fractal dimension is a universal quantity and unaffected
by the choice of metric. We also show that for weak correlations, its value
coincides with that for the uncorrelated system. In two dimensions we observe a
clear increase of the fractal dimension with increasing correlation strength,
approaching . The onset of this change does not seem to
be determined by the extended Harris criterion.Comment: 12 pages, 8 figure
Transition from regular to complex behaviour in a discrete deterministic asymmetric neural network model
We study the long time behaviour of the transient before the collapse on the
periodic attractors of a discrete deterministic asymmetric neural networks
model. The system has a finite number of possible states so it is not possible
to use the term chaos in the usual sense of sensitive dependence on the initial
condition. Nevertheless, at varying the asymmetry parameter, , one observes
a transition from ordered motion (i.e. short transients and short periods on
the attractors) to a ``complex'' temporal behaviour. This transition takes
place for the same value at which one has a change for the mean
transient length from a power law in the size of the system () to an
exponential law in . The ``complex'' behaviour during the transient shows
strong analogies with the chaotic behaviour: decay of temporal correlations,
positive Shannon entropy, non-constant Renyi entropies of different orders.
Moreover the transition is very similar to that one for the intermittent
transition in chaotic systems: scaling law for the Shannon entropy and strong
fluctuations of the ``effective Shannon entropy'' along the transient, for .Comment: 18 pages + 6 figures, TeX dialect: Plain TeX + IOP macros (included
Honeypots and honeynets: issues of privacy
Honeypots and honeynets are popular tools in the area of network security and network forensics. The deployment and usage of these tools are influenced by a number of technical and legal issues, which need to be carefully considered. In this paper, we outline the privacy issues of honeypots and honeynets with respect to their technical aspects. The paper discusses the legal framework of privacy and legal grounds to data processing. We also discuss the IP address, because by EU law, it is considered personal data. The analysis of legal issues is based on EU law and is supported by discussions on privacy and related issues
Relaxation, closing probabilities and transition from oscillatory to chaotic attractors in asymmetric neural networks
Attractors in asymmetric neural networks with deterministic parallel dynamics
were shown to present a "chaotic" regime at symmetry eta < 0.5, where the
average length of the cycles increases exponentially with system size, and an
oscillatory regime at high symmetry, where the typical length of the cycles is
2. We show, both with analytic arguments and numerically, that there is a sharp
transition, at a critical symmetry \e_c=0.33, between a phase where the
typical cycles have length 2 and basins of attraction of vanishing weight and a
phase where the typical cycles are exponentially long with system size, and the
weights of their attraction basins are distributed as in a Random Map with
reversal symmetry. The time-scale after which cycles are reached grows
exponentially with system size , and the exponent vanishes in the symmetric
limit, where . The transition can be related to the dynamics
of the infinite system (where cycles are never reached), using the closing
probabilities as a tool.
We also study the relaxation of the function ,
where is the local field experienced by the neuron . In the symmetric
system, it plays the role of a Ljapunov function which drives the system
towards its minima through steepest descent. This interpretation survives, even
if only on the average, also for small asymmetry. This acts like an effective
temperature: the larger is the asymmetry, the faster is the relaxation of ,
and the higher is the asymptotic value reached. reachs very deep minima in
the fixed points of the dynamics, which are reached with vanishing probability,
and attains a larger value on the typical attractors, which are cycles of
length 2.Comment: 24 pages, 9 figures, accepted on Journal of Physics A: Math. Ge
Farsighted Risk Mitigation of Lateral Movement Using Dynamic Cognitive Honeypots
Lateral movement of advanced persistent threats has posed a severe security
challenge. Due to the stealthy and persistent nature of the lateral movement,
defenders need to consider time and spatial locations holistically to discover
latent attack paths across a large time-scale and achieve long-term security
for the target assets. In this work, we propose a time-expanded random network
to model the stochastic service links in the user-host enterprise network and
the adversarial lateral movement. We design cognitive honeypots at idle
production nodes and disguise honey links as service links to detect and deter
the adversarial lateral movement. The location of the honeypot changes randomly
at different times and increases the honeypots' stealthiness. Since the
defender does not know whether, when, and where the initial intrusion and the
lateral movement occur, the honeypot policy aims to reduce the target assets'
Long-Term Vulnerability (LTV) for proactive and persistent protection. We
further characterize three tradeoffs, i.e., the probability of interference,
the stealthiness level, and the roaming cost. To counter the curse of multiple
attack paths, we propose an iterative algorithm and approximate the LTV with
the union bound for computationally efficient deployment of cognitive
honeypots. The results of the vulnerability analysis illustrate the bounds,
trends, and a residue of LTV when the adversarial lateral movement has infinite
duration. Besides honeypot policies, we obtain a critical threshold of
compromisability to guide the design and modification of the current system
parameters for a higher level of long-term security. We show that the target
node can achieve zero vulnerability under infinite stages of lateral movement
if the probability of movement deterrence is not less than the threshold
Exploring the IL-21–STAT3 Axis as Therapeutic Target for Sézary Syndrome
Sézary syndrome is an aggressive cutaneous T-cell lymphoma. The malignant cells (Sézary cells) are present in skin, lymph nodes, and blood, and express constitutively activated signal transducer and activator of transcription (STAT)3. STAT3 can be activated by IL-21 in vitro and the IL-21 gene itself is a STAT3 target gene, thereby creating an autocrine positive feedback loop that might serve as a therapeutic target. Sézary cells underwent apoptosis when incubated with Stattic, a selective STAT3 inhibitor. STAT3 activation in Sézary cells did not affect expression of the supposed anti-apoptotic STAT3 target genes BCL2, BCL-xL, and SURVIVIN, whereas expression of (proto)oncogenes miR-21, TWIST1, MYC, and PIM1 was significantly increased. CD3/CD28-mediated activation of Sézary cells induced IL-21 expression, accompanied by STAT3 activation and increased proliferation. Blocking IL-21 in CD3/CD28-activated cells had no effects, whereas Stattic abrogated IL-21 expression and cell proliferation. Thus, specific inhibition of STAT3 is highly efficient in the induction of apoptosis of Sézary cells, likely mediated via the regulation of (proto)oncogenes. In contrast, blocking IL-21 alone seems insufficient to affect STAT3 activation, cell proliferation, or apoptosis. These data provide further insights into the pathogenic role of STAT3 in Sézary syndrome and strengthen the notion that STAT3 represents a promising therapeutic target in this disease
Micro-computed tomography and histology to explore internal morphology in decapod larvae
Traditionally, the internal morphology of crustacean larvae has been studied using destructive
techniques such as dissection and microscopy. The present study combines advances in microcomputed
tomography (micro-CT) and histology to study the internal morphology of decapod larvae,
using the common spider crab (Maja brachydactyla Balss, 1922) as a model and resolving the individual
limitations of these techniques. The synergy of micro-CT and histology allows the organs to be easily
identified, revealing simultaneously the gross morphology (shape, size, and location) and histological
organization (tissue arrangement and cell identification). Micro-CT shows mainly the exoskeleton,
musculature, digestive and nervous systems, and secondarily the circulatory and respiratory systems,
while histology distinguishes several cell types and confirms the organ identity. Micro-CT resolves a
discrepancy in the literature regarding the nervous system of crab larvae. The major changes occur in
the metamorphosis to the megalopa stage, specifically the formation of the gastric mill, the shortening
of the abdominal nerve cord, the curving of the abdomen beneath the cephalothorax, and the
development of functional pereiopods, pleopods, and lamellate gills. The combination of micro-CT and
histology provides better results than either one alone.Financial support was provided by the Spanish Ministry of Economy and Competitiveness through the INIA
project (grant number RTA2011-00004-00-00) to G.G. and a pre-doctoral fellowship to D.C. (FPI-INIA)
Historical sampling reveals dramatic demographic changes in western gorilla populations
Background: Today many large mammals live in small, fragmented populations, but it is often unclear whether this subdivision is the result of long-term or recent events. Demographic modeling using genetic data can estimate changes in long-term population sizes while temporal sampling provides a way to compare genetic variation present today with that sampled in the past. In order to better understand the dynamics associated with the divergences of great ape populations, these analytical approaches were applied to western gorillas (Gorilla gorilla) and in particular to the isolated and Critically Endangered Cross River gorilla subspecies (G. g. diehli).Results: We used microsatellite genotypes from museum specimens and contemporary samples of Cross River gorillas to infer both the long-term and recent population history. We find that Cross River gorillas diverged from the ancestral western gorilla population ~17,800 years ago (95% HDI: 760, 63,245 years). However, gene flow ceased only ~420 years ago (95% HDI: 200, 16,256 years), followed by a bottleneck beginning ~320 years ago (95% HDI: 200, 2,825 years) that caused a 60-fold decrease in the effective population size of Cross River gorillas. Direct comparison of heterozygosity estimates from museum and contemporary samples suggests a loss of genetic variation over the last 100 years.Conclusions: The composite history of western gorillas could plausibly be explained by climatic oscillations inducing environmental changes in western equatorial Africa that would have allowed gorilla populations to expand over time but ultimately isolate the Cross River gorillas, which thereafter exhibited a dramatic population size reduction. The recent decrease in the Cross River population is accordingly most likely attributable to increasing anthropogenic pressure over the last several hundred years. Isolation of diverging populations with prolonged concomitant gene flow, but not secondary admixture, appears to be a typical characteristic of the population histories of African great apes, including gorillas, chimpanzees and bonobos
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