314 research outputs found
Информационные технологии в управлении интеллектуальным капиталом организации
The report examines how organization can use information technologies for management of intellectual capital
Serotonin and corticosterone rhythms in mice exposed to cigarette smoke and in patients with COPD:implication for COPD-associated neuropathogenesis
The circadian timing system controls daily rhythms of physiology and behavior, and disruption of clock function can trigger stressful life events. Daily exposure to cigarette smoke (CS) can lead to alteration in diverse biological and physiological processes. Smoking is associated with mood disorders, including depression and anxiety. Patients with chronic obstructive pulmonary disease (COPD) have abnormal circadian rhythms, reflected by daily changes in respiratory symptoms and lung function. Corticosterone (CORT) is an adrenal steroid that plays a considerable role in stress and anti-inflammatory responses. Serotonin (5-hydroxytryptamine; 5HT) is a neurohormone, which plays a role in sleep/wake regulation and affective disorders. Secretion of stress hormones (CORT and 5HT) is under the control of the circadian clock in the suprachiasmatic nucleus. Since smoking is a contributing factor in the development of COPD, we hypothesize that CS can affect circadian rhythms of CORT and 5HT secretion leading to sleep and mood disorders in smokers and patients with COPD. We measured the daily rhythms of plasma CORT and 5HT in mice following acute (3 d), sub-chronic (10 d) or chronic (6 mo) CS exposure and in plasma from non-smokers, smokers and patients with COPD. Acute and chronic CS exposure affected both the timing (peak phase) and amplitude of the daily rhythm of plasma CORT and 5HT in mice. Acute CS appeared to have subtle time-dependent effects on CORT levels but more pronounced effects on 5HT. As compared with CORT, plasma 5HT was slightly elevated in smokers but was reduced in patients with COPD. Thus, the effects of CS on plasma 5HT were consistent between mice and patients with COPD. Together, these data reveal a significant impact of CS exposure on rhythms of stress hormone secretion and subsequent detrimental effects on cognitive function, depression-like behavior, mood/anxiety and sleep quality in smokers and patients with COPD
Determination of the Michel Parameters rho, xi, and delta in tau-Lepton Decays with tau --> rho nu Tags
Using the ARGUS detector at the storage ring DORIS II, we have
measured the Michel parameters , , and for
decays in -pair events produced at
center of mass energies in the region of the resonances. Using
as spin analyzing tags, we find , , , , and . In addition, we report
the combined ARGUS results on , , and using this work
und previous measurements.Comment: 10 pages, well formatted postscript can be found at
http://pktw06.phy.tu-dresden.de/iktp/pub/desy97-194.p
Measurement of the J/Psi Production Cross Section in 920 GeV/c Fixed-Target Proton-Nucleus Interactions
The mid-rapidity (dsigma_(pN)/dy at y=0) and total sigma_(pN) production
cross sections of J/Psi mesons are measured in proton-nucleus interactions.
Data collected by the HERA-B experiment in interactions of 920 GeV/c protons
with carbon, titanium and tungsten targets are used for this analysis. The
J/Psi mesons are reconstructed by their decay into lepton pairs. The total
production cross section obtained is sigma_(pN)(J/Psi) = 663 +- 74 +- 46
nb/nucleon. In addition, our result is compared with previous measurements
A Search for the Electric Dipole Moment of the Tau-Lepton
Using the ARGUS detector at the e+e- storage ring DORIS II, we have searched
for the real and imaginary part of the electric dipole formfactor d_tau of the
tau lepton in the production of tau pairs at q^2=100 GeV^2. This is the first
direct measurement of this CP violating formfactor. We applied the method of
optimised observables which takes into account all available information on the
observed tau decay products. No evidence for CP violation was found, and we
derive the following results: Re(d_tau)=(1.6+-.9)*10^(-16) ecm and
Im(d_tau)=(-0.2+-0.8)*10^(-16) ecm, where statistical and systematic errors
have been combined.Comment: 8 pages, 5 figures (10 subfigures
Open and Hidden Charm Production in 920 GeV Proton-Nucleus Collisions
The HERA-B collaboration has studied the production of charmonium and open
charm states in collisions of 920 GeV protons with wire targets of different
materials. The acceptance of the HERA-B spectrometer covers negative values of
xF up to xF=-0.3 and a broad range in transverse momentum from 0.0 to 4.8
GeV/c. The studies presented in this paper include J/psi differential
distributions and the suppression of J/psi production in nuclear media.
Furthermore, production cross sections and cross section ratios for open charm
mesons are discussed.Comment: 5 pages, 9 figures, to be published in the proceedings of the 6th
International Conference on Hyperons, Charm & Beauty Hadrons (BEACH04),
Chicago, IL, June 27 - July 3, 200
Search for the Flavor-Changing Neutral Current Decay with the HERA-B Detector
We report on a search for the flavor-changing neutral current decay using events recorded with a dimuon trigger in
interactions of 920 GeV protons with nuclei by the HERA-B experiment. We find
no evidence for such decays and set a 90% confidence level upper limit on the
branching fraction .Comment: 17 pages, 4 figures (of which 1 double), paper to be submitted to
Physics Letters
Inclusive Production Cross Sections from 920 GeV Fixed Target Proton-Nucleus Collisions
Inclusive differential cross sections and
for the production of \kzeros, \lambdazero, and
\antilambda particles are measured at HERA in proton-induced reactions on C,
Al, Ti, and W targets. The incident beam energy is 920 GeV, corresponding to
GeV in the proton-nucleon system. The ratios of differential
cross sections \rklpa and \rllpa are measured to be and , respectively, for \xf . No significant dependence upon the
target material is observed. Within errors, the slopes of the transverse
momentum distributions also show no significant
dependence upon the target material. The dependence of the extrapolated total
cross sections on the atomic mass of the target material is
discussed, and the deduced cross sections per nucleon are
compared with results obtained at other energies.Comment: 17 pages, 7 figures, 5 table
Limits for the central production of Θ+ and Ξ−− pentaquarks in 920-GeV pA collisions
We have searched for Θ+(1540) and Ξ−−(1862) pentaquark candidates in proton-inducedreactions on C, Ti, and W targets at midrapidity and s√=41.6 GeV. In 2×108 inelastic eventswe find no evidence for narrow (σ≈5 MeV) signals in the Θ+→pK0S and Ξ−−→Ξ−π− channels; our 95% C.L. upper limits (UL) forthe inclusive production cross section times branching fraction B dσ/dy $y ≈0 are (4-16) μb/N for a Θ+ mass between 1521 and 1555 MeV,and 2.5μb/N for the Ξ−−. The UL of the yield ratio of Θ+/Λ(1520)<(3-12)% is significantly lower than model predictions.Our UL of B Ξ−−/Ξ(1530)0<4% is at variance with the results that have provided the first evidencefor the Ξ−−
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