A method for spatial deconvolution of spectra

A method for spatial deconvolution of spectra is presented. It follows the same fundamental principles as the ``MCS image deconvolution algorithm'' (Magain, Courbin, Sohy, 1998) and uses information contained in the spectrum of a reference Point Spread Function (PSF) to spatially deconvolve spectra of very blended sources. An improved resolution rather than an infinite one is aimed at, overcoming the well known problem of ``deconvolution artefacts''. As in the MCS algorithm, the data are decomposed into a sum of analytical point sources and a numerically deconvolved background, so that the spectrum of extended sources in the immediate vicinity of bright point sources may be accurately extracted and sharpened. The algorithm has been tested on simulated data including seeing variation as a function of wavelength and atmospheric refraction. It is shown that the spectra of severely blended point sources can be resolved while fully preserving the spectrophotometric properties of the data. Extended objects ``hidden'' by bright point sources (up to 4-5 magnitudes brighter) can be accurately recovered as well, provided the data have a sufficiently high total signal-to-noise ratio (200-300 per spectral resolution element). Such spectra are relatively easy to obtain, even down to faint magnitudes, within a few hours of integration time with 10m class telescopes.Comment: 18 pages, 6 postscript figures, in press in Ap

High accuracy transit photometry of the planet OGLE-TR-113b with a new deconvolution-based method

A high accuracy photometry algorithm is needed to take full advantage of the potential of the transit method for the characterization of exoplanets, especially in deep crowded fields. It has to reduce to the lowest possible level the negative influence of systematic effects on the photometric accuracy. It should also be able to cope with a high level of crowding and with large scale variations of the spatial resolution from one image to another. A recent deconvolution-based photometry algorithm fulfills all these requirements, and it also increases the resolution of astronomical images, which is an important advantage for the detection of blends and the discrimination of false positives in transit photometry. We made some changes to this algorithm in order to optimize it for transit photometry and used it to reduce NTT/SUSI2 observations of two transits of OGLE-TR-113b. This reduction has led to two very high precision transit light curves with a low level of systematic residuals, used together with former photometric and spectroscopic measurements to derive new stellar and planetary parameters in excellent agreement with previous ones, but significantly more precise.Comment: 8 pages, 4 figure

A deconvolution-based algorithm for crowded field photometry with unknown Point Spread Function

A new method is presented for determining the Point Spread Function (PSF) of images that lack bright and isolated stars. It is based on the same principles as the MCS (Magain, Courbin, Sohy, 1998) image deconvolution algorithm. It uses the information contained in all stellar images to achieve the double task of reconstructing the PSFs for single or multiple exposures of the same field and to extract the photometry of all point sources in the field of view. The use of the full information available allows to construct an accurate PSF. The possibility to simultaneously consider several exposures makes it very well suited to the measurement of the light curves of blended point sources from data that would be very difficult or even impossible to analyse with traditional PSF fitting techniques. The potential of the method for the analysis of ground-based and space-based data is tested on artificial images and illustrated by several examples, including HST/NICMOS images of a lensed quasar and VLT/ISAAC images of a faint blended Mira star in the halo of the giant elliptical galaxy NGC5128 (Cen A).Comment: Institutes: (1) Institut d'Astrophysique et de Geophysique, Universite de Liege, allee du 6 Aout 17, B-4000 Liege, Belgium; (2) Ecole Polytechnique Federale de Lausanne (EPFL), Laboratoire d'Astrophysique, Observatoire, CH-1290 Sauverny, Switzerland; (3) Observatoire de Geneve, 51 Chemin des Maillettes, CH-1290 Sauverny, Switzerland. 8 pages, 8 figures. Accepted for publication in A&

Deconvolution with correct sampling

A new method for improving the resolution of astronomical images is presented. It is based on the principle that sampled data cannot be fully deconvolved without violating the sampling theorem. Thus, the sampled image should not be deconvolved by the total Point Spread Function, but by a narrower function chosen so that the resolution of the deconvolved image is compatible with the adopted sampling. Our deconvolution method gives results which are, in at least some cases, superior to those of other commonly used techniques: in particular, it does not produce ringing around point sources superimposed on a smooth background. Moreover, it allows to perform accurate astrometry and photometry of crowded fields. These improvements are a consequence of both the correct treatment of sampling and the recognition that the most probable astronomical image is not a flat one. The method is also well adapted to the optimal combination of different images of the same object, as can be obtained, e.g., from infrared observations or via adaptive optics techniques.Comment: 22 pages, LaTex file + 10 color jpg and postscript figures. To be published in ApJ, Vol 484 (1997 Feb.

TOI-2084 b and TOI-4184 b: two new sub-Neptunes around M dwarf stars

We present the discovery and validation of two TESS exoplanets orbiting nearby M dwarfs: TOI-2084b, and TOI-4184b. We characterized the host stars by combining spectra from Shane/Kast and Magellan/FIRE, SED (Spectral Energy Distribution) analysis, and stellar evolutionary models. In addition, we used Gemini-South/Zorro & -North/Alopeke high-resolution imaging, archival science images, and statistical validation packages to support the planetary interpretation. We performed a global analysis of multi-colour photometric data from TESS and ground-based facilities in order to derive the stellar and planetary physical parameters for each system. We find that TOI-2084b and TOI-4184b are sub-Neptune-sized planets with radii of Rp = 2.47 +/- 0.13R_Earth and Rp = 2.43 +/- 0.21R_Earth, respectively. TOI-2084b completes an orbit around its host star every 6.08 days, has an equilibrium temperature of T_eq = 527 +/- 8K and an irradiation of S_p = 12.8 +/- 0.8 S_Earth. Its host star is a dwarf of spectral M2.0 +/- 0.5 at a distance of 114pc with an effective temperature of T_eff = 3550 +/- 50 K, and has a wide, co-moving M8 companion at a projected separation of 1400 au. TOI-4184b orbits around an M5.0 +/- 0.5 type dwarf star (Kmag = 11.87) each 4.9 days, and has an equilibrium temperature of T_eq = 412 +/- 8 K and an irradiation of S_p = 4.8 +/- 0.4 S_Earth. TOI-4184 is a metal poor star ([Fe/H] = -0.27 +/- 0.09 dex) at a distance of 69 pc with an effective temperature of T_eff = 3225 +/- 75 K. Both planets are located at the edge of the sub-Jovian desert in the radius-period plane. The combination of the small size and the large infrared brightness of their host stars make these new planets promising targets for future atmospheric exploration with JWST.Comment: Accepted for publication in A&

TOI-2084 b and TOI-4184 b:two new sub-Neptunes around M dwarf stars

Funding: The research leading to these results has received funding from the ARC grant for Concerted Research Actions, financed by the Wallonia-Brussels Federation. This research is in part funded by the European Union’s Horizon 2020 research and innovation program (grants agreements n◦ 803193/BEBOP), and from the Science and Technology Facilities Council (STFC; grant n◦ ST/S00193X/1). U.G.J. gratefully acknowledges support from tthe European Union H2020-MSCA-ITN-2019 under grant No. 860470 (CHAMELEON). We acknowledge funding from the European Research Council under the ERC Grant Agreement n. 337591-ExTrA.We present the discovery and validation of two TESS exoplanets orbiting nearby M dwarfs: TOI-2084 b, and TOI-4184b. We characterized the host stars by combining spectra from Shane/Kast and Magellan/FIRE, spectral energy distribution analysis, and stellar evolutionary models. In addition, we used Gemini-South/Zorro & -North/Alopeke high-resolution imaging, archival science images, and statistical validation packages to support the planetary interpretation. We performed a global analysis of multi-colour photometric data from TESS and ground-based facilities in order to derive the stellar and planetary physical parameters for each system. We find that TOI-2084 band TOI-4184 bare sub-Neptune-sized planets with radii of Rp = 2.47 ± 0.13R⊕ and Rp = 2.43 ± 0.21 R⊕, respectively. TOI-2084 b completes an orbit around its host star every 6.08 days, has an equilibrium temperature of Teq = 527 ± 8 K and an irradiation of Sp = 12.8 ± 0.8 S⊕. Its host star is a dwarf of spectral M2.0 ± 0.5 at a distance of 114 pc with an effective temperature of Teff = 3550 ± 50 K, and has a wide, co-moving M8 companion at a projected separation of 1400 au. TOI-4184 b orbits around an M5.0 ± 0.5 type dwarf star (Kmag = 11.87) each 4.9 days, and has an equilibrium temperature of Teq = 412 ± 8 K and an irradiation of Sp = 4.8 ± 0.4 S⊕. TOI-4184 is a metal poor star ([Fe/H] = −0.27 ± 0.09 dex) at a distance of 69 pc with an effective temperature of Teff = 3225 ± 75 K. Both planets are located at the edge of the sub-Jovian desert in the radius-period plane. The combination of the small size and the large infrared brightness of their host stars make these new planets promising targets for future atmospheric exploration with JWST.Publisher PDFPeer reviewe

Discovery of WASP-174b : Doppler tomography of a near-grazing transit

We report the discovery and tomographic detection of WASP-174b, a planet with a near-grazing transit on a 4.23-d orbit around a V= 11.9, F6V star with [Fe/H] = 0.09 ± 0.09. The planet is in a moderately misaligned orbit with a sky-projected spin–orbit angle of λ = 31° ± 1°. This is in agreement with the known tendency for orbits around hotter stars to be misaligned. Owing to the grazing transit, the planet’s radius is uncertain with a possible range of 0.8–1.8 RJup. The planet’s mass has an upper limit of 1.3 MJup. WASP-174 is the faintest hot-Jupiter system so far confirmed by tomographic means.Publisher PDFPeer reviewe

CXCR4 Mediated Chemotaxis Is Regulated by 5T4 Oncofetal Glycoprotein in Mouse Embryonic Cells

5T4 oncofetal molecules are highly expressed during development and upregulated in cancer while showing only low levels in some adult tissues. Upregulation of 5T4 expression is a marker of loss of pluripotency in the early differentiation of embryonic stem (ES) cells and forms an integrated component of an epithelial-mesenchymal transition, a process important during embryonic development and metastatic spread of epithelial tumors. Investigation of the transcriptional changes in early ES differentiation showed upregulation of CXCL12 and down-regulation of a cell surface protease, CD26, which cleaves this chemokine. CXCL12 binds to the widely expressed CXCR4 and regulates key aspects of development, stem cell motility and tumour metastasis to tissues with high levels of CXCL12. We show that the 5T4 glycoprotein is required for optimal functional cell surface expression of the chemokine receptor CXCR4 and CXCL12 mediated chemotaxis in differentiating murine embryonic stem cells and embryo fibroblasts (MEF). Cell surface expression of 5T4 and CXCR4 molecules is co-localized in differentiating ES cells and MEF. By contrast, differentiating ES and MEF derived from 5T4 knockout (KO) mice show only intracellular CXCR4 expression but infection with adenovirus encoding mouse 5T4 restores CXCL12 chemotaxis and surface co-localization with 5T4 molecules. A series of chimeric constructs with interchanged domains of 5T4 and the glycoprotein CD44 were used to map the 5T4 sequences relevant for CXCR4 membrane expression and function in 5T4KO MEF. These data identified the 5T4 transmembrane domain as sufficient and necessary to enable CXCR4 cell surface expression and chemotaxis. Furthermore, some monoclonal antibodies against m5T4 can inhibit CXCL12 chemotaxis of differentiating ES cells and MEF which is not mediated by simple antigenic modulation. Collectively, these data support a molecular interaction of 5T4 and CXCR4 occurring at the cell surface which directly facilitates the biological response to CXCL12. The regulation of CXCR4 surface expression by 5T4 molecules is a novel means to control responses to the chemokine CXCL12 for example during embryogenesis but can also be selected to advantage the spread of a 5T4 positive tumor from its primary site

Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland

Dopamine and adrenergic receptor complexes form under a circadian-regulated cycle and directly modulate melatonin synthesis and release from the pineal gland

Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland

Dopamine and adrenergic receptor complexes form under a circadian-regulated cycle and directly modulate melatonin synthesis and release from the pineal gland