416 research outputs found

    Software defined antenna testing

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    Microstrip patch directional antennas are an attractive solution for modern wireless systems due to their high gain and directivity. Being an attractive solution creates the need to design such devices for various application scenarios. We have addressed that need by designing, simulating, and testing a rectangular microstrip patch directional antenna at 5GHz. Antenna patch and ground plane were designed with the well-known guided wavelength equation. The antenna performance, in terms of return loss at -10dB, gain, bandwidth, and the radiation pattern was analyzed with a simulation model. The proposed antenna achieved an impedance bandwidth of 77.8MHz (from 4.9662GHz to 5.0440GHz) and a gain of 6.26dBi at 5GHz. The antenna performance was verified with a software defined radio platform. We found that the software radio measurements confirmed the key simulation results. Furthermore, the extensive use of simulation enabled us to develop both antenna and digital baseband algorithms in parallel

    Needle-free Biojector injection of a dengue virus type 1 DNA vaccine with human immunostimulatory sequences and the GM-CSF gene increases immunogenicity and protection from virus challenge in Aotus monkeys

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    AbstractA dengue-1 DNA vaccine containing sequences encoding premembrane and envelope proteins (DIME) was previously shown to elicit virus neutralizing antibodies in rhesus and Aotus monkeys, and the primates were partially protected from viremia upon challenge. To increase the neutralizing antibody levels and subsequent protection from virus challenge, four strategies were evaluated: (a) coimmunization with a plasmid expressing Aotus GM-CSF gene; (b) coimmunization with a plasmid containing human immunostimulatory sequences (ISS); (c) coimmunization with both the GM-CSF gene and ISS; and (d) delivery of vaccine using the needle-free Biojector system. Vaccination with the mixed formulation containing DIME, GM-CSF gene, and ISS, by either needle injection or Biojector, led to neutralizing antibody titers that were stable for up to 6 months after vaccination. Furthermore, 6 of 7 monkeys (85%), and 7 of 8 monkeys (87%) receiving this formulation were completely protected from viremia when challenged 1 and 6 months after vaccination, respectively. This is a significant improvement compared to our previous study in which one of three monkeys (33%) receiving just the DIME vaccine was completely protected from viremia at 6 months after immunization

    Chandra Observations of Galaxy Zoo Mergers: Frequency of Binary Active Nuclei in Massive Mergers

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    We present the results from a Chandra pilot study of 12 massive galaxy mergers selected from Galaxy Zoo. The sample includes major mergers down to a host galaxy mass of 1011^{11} M⊙M_\odot that already have optical AGN signatures in at least one of the progenitors. We find that the coincidences of optically selected active nuclei with mildly obscured (NH≲1.1×1022N_H \lesssim 1.1 \times 10^{22} cm−2^{-2}) X-ray nuclei are relatively common (8/12), but the detections are too faint (<40< 40 counts per nucleus; f2−10keV≲1.2×10−13f_{2-10 keV} \lesssim 1.2 \times 10^{-13} erg s−1^{-1} cm−2^{-2}) to reliably separate starburst and nuclear activity as the origin of the X-ray emission. Only one merger is found to have confirmed binary X-ray nuclei, though the X-ray emission from its southern nucleus could be due solely to star formation. Thus, the occurrences of binary AGN in these mergers are rare (0-8%), unless most merger-induced active nuclei are very heavily obscured or Compton thick.Comment: 8 pages, including 5 figures and 1 table. Accepted by Ap

    Globally Profiling Sialylation Status of Macrophages Upon Statin Treatment

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    Sialic acids (SAs) are widely expressed on immune cells and their levels and linkages named as sialylation status vary upon cellular environment changes related to both physiological and pathological processes. In this study, we performed a global profiling of the sialylation status of macrophages and their release of SAs in the cell culture medium by using flow cytometry, confocal microscopy and liquid chromatography tandem mass spectrometry (LC-MS/MS). Both flow cytometry and confocal microscopy results showed that cell surface α-2,3-linked SAs were predominant in the normal culture condition and changed slightly upon treatment with atorvastatin for 24 h, whereas α-2,6-linked SAs were negligible in the normal culture condition but significantly increased after treatment. Meanwhile, the amount of total cellular SAs increased about three times (from 369 ± 29 to 1080 ± 50 ng/mL) upon treatment as determined by the LC-MS/MS method. On the other hand, there was no significant change for secreted free SAs and conjugated SAs in the medium. These results indicated that the cell surface α-2,6 sialylation status of macrophages changes distinctly upon atorvastatin stimulation, which may reflect on the biological functions of the cells

    Bottom and Suspended Sediment Backscatter Measurements in a Flume—Towards Quantitative Bed and Water Column Properties

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    For health and impact studies of water systems, monitoring underwater environments is essential, for which multi-frequency single- and multibeam echosounders are commonly used state-of-the-art technologies. However, the current scarcity of sediment reference datasets of both bottom backscatter angular response and water column scattering hampers empirical data interpretation. Comprehensive reference data derived from measurements in a controlled environment should optimize the use of empirical backscatter data. To prepare for such innovative experiments, we conducted a feasibility experiment in the Delta Flume (Deltares, The Netherlands). Several configurations of sonar data were recorded of the flume floor and suspended sediment plumes. The results revealed that flume reverberation was sufficiently low and that the differential settling of fine-sand plumes in the water column was clearly detected. Following this successful feasibility test, future comprehensive experiments will feature multi-frequency multi-angle measurements on a variety of sediment types, additional scatterers and sediment plumes, resulting in reference datasets for an improved interpretation of underwater backscatter measurements for scientific observation and sustainable management

    Tracing Sagittarius Structure with SDSS and SEGUE Imaging and Spectroscopy

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    We show that the Sagittarius dwarf tidal stream can be traced with very red K/M-giant stars selected from SDSS photometry. A subset of these stars are spectroscopically confirmed with SEGUE and SDSS spectra, and the distance scale of 2MASS and SDSS M giants is calibrated to the RR Lyrae distance scale. The absolute g band magnitude of the K/M-giant stars at the tip of the giant branch is M_g=-1.0. The line-of-sight velocities of the M giant and BHB stars that are spatially coincident with the Sgr dwarf tidal stream are consistent with those of previous authors, reinforcing the need for new models that can explain all of the Sgr tidal debris stream observations. We estimate stellar densities along the tidal tails that can be used to help constrain future models. The K/M-giant, BHB, and F-turnoff stars in the lower surface brightness tidal stream that is adjacent to the main leading Sgr dwarf tidal tail have velocities and metallicities that are similar to those of the stars in the leading tidal tail. The ratio of K/M giants to BHBs and BHBs to F-turnoff stars are also similar for both branches of the leading tidal tail. We show that there is an additional low-metallicity tidal stream near the Sgr trailing tidal tail.Comment: 19 figures, accepted for publication in ApJ, references update

    Galactic Globular and Open Clusters in the Sloan Digital Sky Survey. I. Crowded Field Photometry and Cluster Fiducial Sequences in ugriz

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    We present photometry for globular and open cluster stars observed with the Sloan Digital Sky Survey (SDSS). In order to exploit over 100 million stellar objects with r < 22.5 mag observed by SDSS, we need to understand the characteristics of stars in the SDSS ugriz filters. While star clusters provide important calibration samples for stellar colors, the regions close to globular clusters, where the fraction of field stars is smallest, are too crowded for the standard SDSS photometric pipeline to process. To complement the SDSS imaging survey, we reduce the SDSS imaging data for crowded cluster fields using the DAOPHOT/ALLFRAME suite of programs and present photometry for 17 globular clusters and 3 open clusters in a SDSS value-added catalog. Our photometry and cluster fiducial sequences are on the native SDSS 2.5-meter ugriz photometric system, and the fiducial sequences can be directly applied to the SDSS photometry without relying upon any transformations. Model photometry for red giant branch and main-sequence stars obtained by Girardi et al. cannot be matched simultaneously to fiducial sequences; their colors differ by ~0.02-0.05 mag. Good agreement (< ~0.02 mag in colors) is found with Clem et al. empirical fiducial sequences in u'g'r'i'z' when using the transformation equations in Tucker et al.Comment: 30 pages, 25 figures. Accepted for publication in ApJS. Version with high resolution figures available at http://www.astronomy.ohio-state.edu/~deokkeun/AnJohnson.pd

    The kinematics of late type stars in the solar cylinder studied with SDSS data

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    We study the velocity distribution of Milky Way disk stars in a kiloparsec-sized region around the Sun, based on ~ 2 million M-type stars from DR7 of SDSS, which have newly re-calibrated absolute proper motions from combining SDSS positions with the USNO-B catalogue. We estimate photometric distances to all stars, accurate to ~ 20 %, and combine them with the proper motions to derive tangential velocities for this kinematically unbiased sample of stars. Based on a statistical de-projection method we then derive the vertical profiles (to heights of Z = 800 pc above the disk plane) for the first and second moments of the three dimensional stellar velocity distribution. We find that = -7 +/- 1 km/s and = -9 +/- 1 km/s, independent of height above the mid-plane, reflecting the Sun's motion with respect to the local standard of rest. In contrast, changes distinctly from -20 +/- 2 km/s in the mid-plane to = -32 km/s at Z = 800 pc, reflecting an asymmetric drift of the stellar mean velocity that increases with height. All three components of the M-star velocity dispersion show a strong linear rise away from the mid-plane, most notably \sigma_{ZZ}, which grows from 18 km/s (Z = 0) to 40 km/s (at Z = 800 pc). We determine the orientation of the velocity ellipsoid, and find a significant vertex deviation of 20 to 25 degrees, which decreases only slightly to heights of Z = 800 pc. Away from the mid-plane, our sample exhibits a remarkably large tilt of the velocity ellipsoid towards the Galactic plane, which reaches 20 deg. at Z = 800 pc and which is not easily explained. Finally, we determine the ratio \sigma^2_{\phi\phi}/\sigma^2_{RR} near the mid-plane, which in the epicyclic approximation implies an almost perfectly flat rotation curve at the Solar radius.Comment: 18 pages, 9 figures, accepted to Astron.

    Efficient Dehydration and Recovery of Ionic Liquid After Lignocellulosic Processing Using Pervaporation

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    Background: Biomass pretreatment using certain ionic liquids (ILs) is very efficient, generally producing a substrate that is amenable to saccharification with fermentable sugar yields approaching theoretical limits. Although promising, several challenges must be addressed before an IL pretreatment technology can become commercially viable. One of the most significant challenges is the affordable and scalable recovery and recycle of the IL itself. Pervaporation (PV) is a highly selective and scalable membrane separation process for quantitatively recovering volatile solutes or solvents directly from non-volatile solvents that could prove more versatile for IL dehydration. Results: We evaluated a commercially available PV system for IL dehydration and recycling as part of an integrated IL pretreatment process using 1-ethyl-3-methylimidazolium acetate ([C2C1Im][OAc]) that has been proven to be very effective as a biomass pretreatment solvent. Separation factors as high as 1500 were observed. We demonstrate that \u3e 99.9 wt% [C2C1Im][OAc] can be recovered from aqueous solution (≤ 20 wt% IL) and recycled five times. A preliminary technoeconomic analysis validated the promising role of PV in improving overall biorefinery process economics, especially in the case where other IL recovery technologies might lead to significant losses. Conclusions: These findings establish the foundation for further development of PV as an effective method of recovering and recycling ILs using a commercially viable process technology

    Type Ia Supernova Properties as a Function of the Distance to the Host Galaxy in the SDSS-II SN Survey

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    We use type-Ia supernovae (SNe Ia) discovered by the SDSS-II SN Survey to search for dependencies between SN Ia properties and the projected distance to the host galaxy center, using the distance as a proxy for local galaxy properties (local star-formation rate, local metallicity, etc.). The sample consists of almost 200 spectroscopically or photometrically confirmed SNe Ia at redshifts below 0.25. The sample is split into two groups depending on the morphology of the host galaxy. We fit light-curves using both MLCS2k2 and SALT2, and determine color (AV, c) and light-curve shape (delta, x1) parameters for each SN Ia, as well as its residual in the Hubble diagram. We then correlate these parameters with both the physical and the normalized distances to the center of the host galaxy and look for trends in the mean values and scatters of these parameters with increasing distance. The most significant (at the 4-sigma level) finding is that the average fitted AV from MLCS2k2 and c from SALT2 decrease with the projected distance for SNe Ia in spiral galaxies. We also find indications that SNe in elliptical galaxies tend to have narrower light-curves if they explode at larger distances, although this may be due to selection effects in our sample. We do not find strong correlations between the residuals of the distance moduli with respect to the Hubble flow and the galactocentric distances, which indicates a limited correlation between SN magnitudes after standardization and local host metallicity.Comment: Accepted for publication in The Astrophysical Journal (33 pages, 5 figures, 8 tables
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