Like a Carsic River: Gay Independent Cinema from Underground Films to New Queer Cinema and Beyond

Like a Carsic River: Gay Independent Cinema from Underground Films to New Queer Cinema and Beyond

The antimicrobial photodynamic therapy in the treatment of peri-implantitis

The aim of this study is to demonstrate the effectiveness of addition of the antimicrobial photodynamic therapy to the conventional approach in the treatment of peri-implantitis. Materials and Methods. Forty patients were randomly assigned to test or control groups. Patients were assessed at baseline and at six (T1), twelve (T2), and twenty-four (T3) weeks recording plaque index (PlI), probing pocket depth (PPD), and bleeding on probing (BOP); control group received conventional periodontal therapy, while test group received photodynamic therapy in addition to it. Result. Test group showed a 70% reduction in the plaque index values and a 60% reduction in PD values compared to the baseline. BOP and suppuration were not detectable. Control group showed a significative reduction in plaque index and PD. Discussion. Laser therapy has some advantages in comparison to traditional therapy, with faster and greater healing of the wound. Conclusion. Test group showed after 24 weeks a better value in terms of PPD, BOP, and PlI, with an average pocket depth value of 2 mm, if compared with control group (3 mm).Our results suggest that antimicrobial photodynamic therapy with diode laser and phenothiazine chloride represents a reliable adjunctive treatment to conventional therapy. Photodynamic therapy should, however, be considered a coadjuvant in the treatment of peri-implantitis associated with mechanical (scaling) and surgical (grafts) treatments

Survey of the Ridracoli Dam: UAV – Based Photogrammetry and Traditional Topographic Techniques in the Inspection of Vertical Structures*

The inspection of strategic works such as dams is of vital importance both for their maintenance and for the safety of downstream populations. The reduced accessibility, both for uptake needs and for their strategic nature, and the large time needed for an inspection by traditional method do not facilitate the investigation of this type of structures. The new unmanned aerial vehicle (UAV) technology, equipped with high-performance cameras, allows for rapid photographic coverage of the whole dam system. Apart from the placement on the structure of a high number of markers, the correct geo-referencing and validation of the model also requires an important terrestrial topographic campaign by total station, Global Positioning System and laser scanner. Punctual, linear and surface analysis shows the high accuracy of the drone acquiring technique. The product is suitable for a detailed survey of the conservation status of the materials and the complete metric reconstruction of the dam system and the adjacent land. The present work explains firstly a UAV acquisition and then the first dense point cloud validation procedure of a concrete arch gravity dam. The Ridracoli dam is the object of the survey, located in the village of Santa Sofia in central Italy

Multimodal treatment for local recurrent malignant gliomas: resurgery and/or reirradiation followed by chemotherapy

The therapeutic management of recurrent malignant gliomas (MGs) is not determined. Therefore, the efficacy of a multimodal approach and a combination systemic therapy was investigated. A retrospective analysis of 26 MGs patients at first relapse treated with multimodal therapy (chemotherapy plus surgery and/or reirradiation) or chemotherapy alone was performed. Second-line chemotherapy consisted of fotemustine (FTM) in combination with bevacizumab (BEV) (cFTM/BEV) or followed by third-line BEV (sFTM/BEV). Subgroup analyses were performed. Multimodal therapy provided a higher overall response rate (ORR) (73 vs. 47%), disease control rate (DCR) (82 vs. 67%), median progression-free survival (mPFS) (11 vs. 7 months; P=0.08) and median overall survival (mOS) (13 vs. 8 months; P=0.04) compared with chemotherapy. Concomitant FTM/BEV resulted in higher ORR (84 vs. 36%), DCR (92 vs. 57%), mPFS (10 vs. 5 months; P=0.22) and mOS (11 vs. 5.2 months; P=0.15) compared with sFTM/BEV. Methylated patients did not experience additional survival benefits with multimodality treatment but had higher mPFS (10 vs 7.1 months; P=0.33) and mOS (11 vs. 8 months; P=0.33) with cFTM/BEV. Unmethylated patients experienced the greatest survival benefit with the multimodal approach (mPFS: 10 vs. 5 months; mOS 11 vs 6 months; both P=0.02) and cFTM/BEV (mPFS: 5 vs. 2 months; mOS 6 vs. 3.2 months; both P=0.01). In conclusion, in recurrent MGs, multimodal therapy and cFTM/BEV provide survival and response benefits. Methylated patients benefit from a cFTM/BEV but not from a multimodal approach. Notably, unmethylated patients had the highest survival benefit with the two strategies

On the accuracy of UAV photogrammetric survey for the evaluation of historic masonry structural damages

Abstract Photogrammetric surveys via Unmanned Aerial Vehicles are nowadays a valuable tool for historic masonry structures inspection, surveillance, mapping and 3D modeling issues. When structural damage mapping and structural assessment are of interest obtaining accurate and reliable geometric models is a crucial issue. Therefore, the flight plan, the georeferencing and the data processing steps need to be properly designed. In this paper, a procedure for the photogrammetric survey via Unmanned Aerial Vehicles of a masonry structures is used in order to obtain effective visual inspections and a 3D model of a historic masonry arch bridge located along the ancient Via Amerina (Todi, Perugia, Italy). The photogrammetric survey provides a detailed representation of the actual geometry, including lack of volumes and significant cracks along the vault and the spandrel walls, outlining a severe damage state affecting all the structure. Finally, a Total Station and a Laser Scanner were used to compare the results obtained by photogrammetry, highlighting the advantages, the limits and the weaknesses offered by their use