885 research outputs found
Distribuição e conservação do rato-do-bambu Kannabateomys amblyonyx (Rodentia, Echimyidae) no Estado de Minas Gerais, Brasil
This note reports data on occurrence of the echimyid Kannabateomys amblyonyx in Minas Gerais State, southeastern Brazil. Data were obtained from consult to 26 museums, bibliography search and field sampling. We found nine municipalities with species records, eight within the Atlantic Forest biome and one in the transitional area between the Atlantic Forest and Cerrado. Habitats occupied comprised bamboo groves in Montane Stational Semidecidual Forest, Submontane Stational Semidecidual Forest and bamboo patches located in middle of open area, originally covered by Submontane Stational Semidecidual Forest. Potential impacts detected were deforestation, fires, hunting and the presence of livestock and domestic dogs. Key words: bamboo rat, Atlantic Forest, threats, records.Este trabalho apresenta dados sobre a ocorrência do equimídeo Kannabateomys amblyonyx no Estado de Minas Gerais, sudeste do Brasil. Dados foram obtidos a partir de consultas a 26 museus, pesquisa bibliográfica e de amostragens de campo. Encontramos nove municípios com registros da espécie, sendo oito inseridos no bioma Mata Atlântica e um em área de transição entre Mata Atlântica e Cerrado. Os habitats ocupados compreenderam bambuzais em Floresta Estacional Semidecidual Montana, Floresta Estacional Semidecidual Submontana e manchas de bambu localizadas em meio a áreas aberta, originalmente coberta por Floresta Estacional Semidecidual Submontana. Os potenciais impactos detectados foram desmatamento, queimadas, caça e presença de gado e cães domésticos.Palavras-chave: rato-do-bambu, Mata Atlântica, ameaças, registros
Data management plan to support FAIR scientific management data
Relata os avanços no desenvolvimento da plataforma que servirá como Cadastro Nacional de Planos de Gestão de Dados, sediada pelo Instituto Brasileiro de Informação em Ciência e Tecnologia (IBICT), em busca de uma ciência brasileira mais aberta e acessível. Este roteiro é desenhado de acordo com tendências globais, padrões-ouro como os Princípios FAIR e as 5 Estrelas para Dados Abertos de Tim berners-Lee, os quais enquadram as decisões que foram tomadas para se alinhar com a situação das organizações financiadoras de projetos de pesquisa e entidades acadêmicas. Para estruturar o PGD IBICT, analisamos práticas utilizadas no desenvolvimento de ferramentas para PGDs em nível internacional, e descrevemos os principais recursos que foram adaptados ao modelo em construção. Descrevemos, além disso, a experiência e os resultados do projeto piloto, incluindo a template e principais funcionalidades. Finalmente, é apresentado o workflow de funcionamento do PGD IBICT.It reports on progress in the development of the platform that will serve as the National Registry of Data Management Plans, hosted by the Brazilian Institute for Information in Science and Technology (known as IBICT), in pursuit of a more open and accessible Brazilian science. This roadmap is designed according to global trends, gold standards such as the FAIR Principles and Tim Berners-Lee's 5-Star Open Data, which frame the decisions that have been made to align with the situation of research funding organizations and academic entities. To structure the DMP by IBICT, we analyze practices used in the development of tools for DMPs at the international level, and describe the main features that were adapted to the model under construction. We also describe the experience and results of the pilot project, including the template and main features. Finally, the workflow for the operation of the DMP by IBICT is presented
Preservation of data management plans: Hipátia model
Plano de Gestão de Dados é um documento onde são descritas as etapas e decisões sobre a gestão de dados científicos. Existem plataformas que auxiliam em sua elaboração, entretanto, não são iniciativas centralizadas para a preservação desses documentos. O Cadastro Nacional de Planos de Gestão de Dados do Instituto Brasileiro de Informação em Ciência e Tecnologia (IBICT) tem o projeto para desenvolver e disponibilizar publicamente uma ferramenta que atenda tais demandas. A ferramenta tem como principal característica atender aos Princípios FAIR e às 5 Estrelas para Dados Abertos de Tim Berners-Lee. Assim, o objetivo deste artigo é apresentar a estratégia para a preservação do Plano de Gestão de Dados do projeto Plano de Gestão de Dados FAIR do IBICT. O repositório Dataverse do IBICT, por meio do modelo Hipátia de preservação digital, vai preservar tais planos. Um cadastro nacional de PGDs pode ser considerado um recurso estratégico, tendo em vista a necessidade permanente de oferecer visibilidade e transparência sobre as pesquisas realizadas no Brasil.Data Management Plan is a document where the steps and decisions about the management of scientific data are described. There are platforms that assist in its elaboration, however, they are not centralized initiatives for the preservation of these documents. The National Registry of Data Management Plans of the Brazilian Institute for Information in Science and Technology (IBICT) has the project to develop and make publicly available a tool that meets such demands. The tool has as its main characteristic to meet the FAIR Principles and the 5 Stars for Open Data of Tim Berners-Lee. Thus the goal of this paper is to present the strategy for the preservation of IBICT's FAIR Data Management Plan project.IBICT's Dataverse repository, through the Hipátia model of digital preservation, will preserve such plans. A national PGD registry can be considered a strategic resource, considering the permanent need to provide visibility and transparency about the research conducted in Brazil
Combination of Melatonin and Metformin Hydrochloride for Treatment Polycystic Ovarian in Female Rats
Background: Polycystic ovary syndrome (PCOS) is a gynecological endocrine disorder, results in menstrual abnormalities, androgynism and infertility. In the case of women or others animals with PCOS wishing to treat infertility with the aim of becoming pregnant, the most commonly used is metformin hydrochloride. Recent studies have analyzed the combination of metformin hydrochloride with melatonin in oncological treatment but not to treatment of polycystic ovary syndrome (PCOS). The aim of the present study was to analyze the effectiveness of the combination of metformin hydrochloride and melatonin in the treatment of PCOS to improve the fertility of rats and your hormonal alterations.Materials, Methods & Results: This study was carried out in strict accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health. The protocol was approved by the Committee on the Ethics of Animal Experiments of the University of Federal Rural of Pernambuco (Permit Number: 23081.009130/2010). A total of 50 albino Wistar rats were used. The animal laboratory of an academic research environment, were randomly separated into five groups consisting of 10 females each. After inducing PCOS, the rats were treated with metformin hydrochloride, and/or melatonin, and the results compared with standard and ultrasound confirmed. The physiological similarities were confirmed by our academic researchers morphological science, and published to the association results of effects syndrome induction through constant lighting in reputable magazine recently. This article was analyzed histological of the implantation sites and ovaries, and the estradiol and progesterone levels on the seventh day of gestation, and the other rats for monitoring pregnancy and morphological identification of possible fetal abnormalities, weight measurement and quantification of offspring. The rats were anaesthetized with intraperitoneal injections of ketamine hydrochloride (80 mg/kg) and xylazine (6 mg/kg) to allow analysis of the reproductive organs. Main outcome measures: The study included histopathology, histochemical and quantitative (of the implantation sites) tests, ultrasound analysis, weight benchmarking and ovarian histology tests, as well as comparison of serum estradiol and progesterone levels, and the morphological assessment of offspring. Results paper shows pharmacological treatment reduced the time needed for pregnancy, increased the plasma progesterone levels, the number and weight of offspring, and reduced plasma estrogen levels and collagen fiber grade, improving blastocyst-endometrium interaction and fetal development.Discussion: Our team of researchers confirmed in a previous paper; in addition, the main experimental model used in research about PCOS in recent years, and considered appropriate combination of the drugs caused a physiological reaction similar to responses identified in healthy rats without induction of the POS control group. However, the clinical and physiological effectiveness of the combination should be further explored, especially with respect to the possible side effects on offspring. The treatment with a combination of metformin hydrochloride and melatonin was more effective against hormonal alterations produced by PCOS, allowing a normalization of biochemical parameters during pregnancy, than monotherapeutic treatment with these drugs. In conclusion, proposed drug combination is a viable option to treatment of polycystic ovary syndrome and improved fetal development. This article allows suggest that further research should be conducted to examine effects associated with these drugs in the treatment of diseases of the female reproductive system experimentally. Only such treatment later in animals and humans suggest
Precision measurement of violation in the penguin-mediated decay
A flavor-tagged time-dependent angular analysis of the decay
is performed using collision data collected
by the LHCb experiment at % at TeV, the center-of-mass energy of
13 TeV, corresponding to an integrated luminosity of 6 fb^{-1}. The
-violating phase and direct -violation parameter are measured
to be rad and
, respectively, assuming the same values
for all polarization states of the system. In these results, the
first uncertainties are statistical and the second systematic. These parameters
are also determined separately for each polarization state, showing no evidence
for polarization dependence. The results are combined with previous LHCb
measurements using collisions at center-of-mass energies of 7 and 8 TeV,
yielding rad and . This is the most precise study of time-dependent violation
in a penguin-dominated meson decay. The results are consistent with
symmetry and with the Standard Model predictions.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2023-001.html (LHCb
public pages
Measurement of the differential branching fraction
The branching fraction of the rare decay is measured for the first time, in the squared dimuon mass
intervals, , excluding the and regions. The data
sample analyzed was collected by the LHCb experiment at center-of-mass energies
of 7, 8, and 13 TeV, corresponding to a total integrated luminosity of $9\
\mathrm{fb}^{-1}q^{2}q^{2} >15.0\
\mathrm{GeV}^2/c^4$, where theoretical predictions have the smallest model
dependence, agrees with the predictions.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-050.html (LHCb
public pages
Study of the decay
The decay is studied
in proton-proton collisions at a center-of-mass energy of TeV
using data corresponding to an integrated luminosity of 5
collected by the LHCb experiment. In the system, the
state observed at the BaBar and Belle experiments is
resolved into two narrower states, and ,
whose masses and widths are measured to be where the first uncertainties are statistical and the second
systematic. The results are consistent with a previous LHCb measurement using a
prompt sample. Evidence of a new
state is found with a local significance of , whose mass and width
are measured to be and , respectively. In addition, evidence of a new decay mode
is found with a significance of
. The relative branching fraction of with respect to the
decay is measured to be , where the first
uncertainty is statistical, the second systematic and the third originates from
the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb
public pages
Observation of Cabibbo-suppressed two-body hadronic decays and precision mass measurement of the baryon
The first observation of the singly Cabibbo-suppressed
and decays
is reported, using proton-proton collision data at a centre-of-mass energy of
, corresponding to an integrated luminosity of , collected with the LHCb detector between 2016 and 2018. The
branching fraction ratios are measured to be
,
. In addition, using the
decay channel, the baryon
mass is measured to be , improving the
precision of the previous world average by a factor of four.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2023-011.html (LHCb
public pages
Test of lepton universality in decays
The first simultaneous test of muon-electron universality using
and decays is performed, in two ranges of the dilepton
invariant-mass squared, . The analysis uses beauty mesons produced in
proton-proton collisions collected with the LHCb detector between 2011 and
2018, corresponding to an integrated luminosity of 9 . Each
of the four lepton universality measurements reported is either the first in
the given interval or supersedes previous LHCb measurements. The
results are compatible with the predictions of the Standard Model.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-046.html (LHCb
public pages
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