Overview of the subsonic propulsion technology session

NASA is conducting aeronautical research over a broad range of Mach numbers. In addition to the generic and high speed propulsion research, the Lewis Research Center is continuing its substantial efforts towards propulsion technology for a broad range of subsonic flight applications. Reviewed here are some of the elements of that program, including small engine technology, rotorcraft, icing research, hot section technology, and the Advanced Turboprop Project

NASA advanced turboprop research and concept validation program

NASA has determined by experimental and analytical effort that use of advanced turboprop propulsion instead of the conventional turbofans in the older narrow-body airline fleet could reduce fuel consumption for this type of aircraft by up to 50 percent. In cooperation with industry, NASA has defined and implemented an Advanced Turboprop (ATP) program to develop and validate the technology required for these new high-speed, multibladed, thin, swept propeller concepts. This paper presents an overview of the analysis, model-scale test, and large-scale flight test elements of the program together with preliminary test results, as available

MeerTime - the MeerKAT Key Science Program on Pulsar Timing

The MeerKAT telescope represents an outstanding opportunity for radio pulsar timing science with its unique combination of a large collecting area and aperture efficiency (effective area $\sim$7500 m$^2$), system temperature ($T<20$K), high slew speeds (1-2 deg/s), large bandwidths (770 MHz at 20cm wavelengths), southern hemisphere location (latitude $\sim -30^\circ$) and ability to form up to four sub-arrays. The MeerTime project is a five-year program on the MeerKAT array by an international consortium that will regularly time over 1000 radio pulsars to perform tests of relativistic gravity, search for the gravitational wave signature induced by supermassive black hole binaries in the timing residuals of millisecond pulsars, explore the interiors of neutron stars through a pulsar glitch monitoring programme, explore the origin and evolution of binary pulsars, monitor the swarms of pulsars that inhabit globular clusters and monitor radio magnetars. In addition to these primary programmes, over 1000 pulsars will have their arrival times monitored and the data made immediately public. The MeerTime pulsar backend comprises two server-class machines each of which possess four Graphics Processing Units. Up to four pulsars can be coherently dedispersed simultaneously up to dispersion measures of over 1000 pc cm$^{-3}$. All data will be provided in psrfits format. The MeerTime backend will be capable of producing coherently dedispersed filterbank data for timing multiple pulsars in the cores of globular clusters that is useful for pulsar searches of tied array beams. All MeerTime data will ultimately be made available for public use, and any published results will include the arrival times and profiles used in the results.Comment: 15 pages, MeerKAT Science: On the Pathway to the SKA, 25-27 May, 2016, Stellenbosch, South Africa, available at: https://pos.sissa.it/277/011/pd

CMB observations from the CBI and VSA: A comparison of coincident maps and parameter estimation methods

We present coincident observations of the Cosmic Microwave Background (CMB) from the Very Small Array (VSA) and Cosmic Background Imager (CBI) telescopes. The consistency of the full datasets is tested in the map plane and the Fourier plane, prior to the usual compression of CMB data into flat bandpowers. Of the three mosaics observed by each group, two are found to be in excellent agreement. In the third mosaic, there is a 2 sigma discrepancy between the correlation of the data and the level expected from Monte Carlo simulations. This is shown to be consistent with increased phase calibration errors on VSA data during summer observations. We also consider the parameter estimation method of each group. The key difference is the use of the variance window function in place of the bandpower window function, an approximation used by the VSA group. A re-evaluation of the VSA parameter estimates, using bandpower windows, shows that the two methods yield consistent results.Comment: 10 pages, 6 figures. Final version. Accepted for publication in MNRA

Solar Neutrino Constraints on the BBN Production of Li

Using the recent WMAP determination of the baryon-to-photon ratio, 10^{10} \eta = 6.14 to within a few percent, big bang nucleosynthesis (BBN) calculations can make relatively accurate predictions of the abundances of the light element isotopes which can be tested against observational abundance determinations. At this value of \eta, the Li7 abundance is predicted to be significantly higher than that observed in low metallicity halo dwarf stars. Among the possible resolutions to this discrepancy are 1) Li7 depletion in the atmosphere of stars; 2) systematic errors originating from the choice of stellar parameters - most notably the surface temperature; and 3) systematic errors in the nuclear cross sections used in the nucleosynthesis calculations. Here, we explore the last possibility, and focus on possible systematic errors in the He3(\alpha,\gamma)Be7 reaction, which is the only important Li7 production channel in BBN. The absolute value of the cross section for this key reaction is known relatively poorly both experimentally and theoretically. The agreement between the standard solar model and solar neutrino data thus provides additional constraints on variations in the cross section (S_{34}). Using the standard solar model of Bahcall, and recent solar neutrino data, we can exclude systematic S_{34} variations of the magnitude needed to resolve the BBN Li7 problem at > 95% CL. Additional laboratory data on He3(\alpha,\gamma)Be7 will sharpen our understanding of both BBN and solar neutrinos, particularly if care is taken in determining the absolute cross section and its uncertainties. Nevertheless, it already seems that this ``nuclear fix'' to the Li7 BBN problem is unlikely; other possible solutions are briefly discussed.Comment: 21 pages, 3 ps figure

Why Are Outcomes Different for Registry Patients Enrolled Prospectively and Retrospectively? Insights from the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF).

Background: Retrospective and prospective observational studies are designed to reflect real-world evidence on clinical practice, but can yield conflicting results. The GARFIELD-AF Registry includes both methods of enrolment and allows analysis of differences in patient characteristics and outcomes that may result. Methods and Results: Patients with atrial fibrillation (AF) and ≥1 risk factor for stroke at diagnosis of AF were recruited either retrospectively (n = 5069) or prospectively (n = 5501) from 19 countries and then followed prospectively. The retrospectively enrolled cohort comprised patients with established AF (for a least 6, and up to 24 months before enrolment), who were identified retrospectively (and baseline and partial follow-up data were collected from the emedical records) and then followed prospectively between 0-18 months (such that the total time of follow-up was 24 months; data collection Dec-2009 and Oct-2010). In the prospectively enrolled cohort, patients with newly diagnosed AF (≤6 weeks after diagnosis) were recruited between Mar-2010 and Oct-2011 and were followed for 24 months after enrolment. Differences between the cohorts were observed in clinical characteristics, including type of AF, stroke prevention strategies, and event rates. More patients in the retrospectively identified cohort received vitamin K antagonists (62.1% vs. 53.2%) and fewer received non-vitamin K oral anticoagulants (1.8% vs . 4.2%). All-cause mortality rates per 100 person-years during the prospective follow-up (starting the first study visit up to 1 year) were significantly lower in the retrospective than prospectively identified cohort (3.04 [95% CI 2.51 to 3.67] vs . 4.05 [95% CI 3.53 to 4.63]; p = 0.016). Conclusions: Interpretations of data from registries that aim to evaluate the characteristics and outcomes of patients with AF must take account of differences in registry design and the impact of recall bias and survivorship bias that is incurred with retrospective enrolment. Clinical Trial Registration: - URL: http://www.clinicaltrials.gov . Unique identifier for GARFIELD-AF (NCT01090362)

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Collimation for the LHC high intensity beams

The unprecedented design intensities of the LHC require several important advances in beam collimation. With its more than 100 collimators, acting on various planes and beams, the LHC collimation system is the biggest and most performing such system ever designed and constructed. The solution for LHC collimation is explained, the technical components are introduced and the initial performance is presented. Residual beam leakage from the system is analysed. Measurements and simulations are presented which show that collimation efficiencies of better than 99.97 % have been measured with the 3.5 TeV proton beams of the LHC, in excellent agreement with expectations.peer-reviewe

MeerTime - the MeerKAT Key science program on pulsar timing

© Copyright owned by the author(s). The MeerKAT telescope represents an outstanding opportunity for radio pulsar timing science with its unique combination of a large collecting area and aperture efficiency (effective area ~7500 m2), system temperature (T &lt; 20K), high slew speeds (1-2 deg/s), large bandwidths (770 MHz at 20cm wavelengths), southern hemisphere location (latitude ~ -30?) and ability to form up to four sub-arrays. The MeerTime project is a five-year program on the MeerKAT array by an international consortium that will regularly time over 1000 radio pulsars to perform tests of relativistic gravity, search for the gravitational wave signature induced by supermassive black hole binaries in the timing residuals of millisecond pulsars, explore the interiors of neutron stars through a pulsar glitch monitoring programme, explore the origin and evolution of binary pulsars, monitor the swarms of pulsars that inhabit globular clusters and monitor radio magnetars. MeerTime will complement the TRAPUM project and time pulsars TRAPUM discovers in surveys of the galactic plane, globular clusters and the galactic centre. In addition to these primary programmes, over 1000 pulsars will have their arrival times monitored and the data made immediately public. The MeerTime pulsar backend comprises two server-class machines each of which possess four Graphics Processing Units. Up to four pulsars can be coherently dedispersed simultaneously up to dispersion measures of over 1000 pc cm-3. All data will be provided in psrfits format. The MeerTime backend will be capable of producing coherently dedispersed filterbank data for timing multiple pulsars in the cores of globular clusters that is useful for pulsar searches of tied array beams. The first real-time pulsar profiles have been obtained as part of the MeerKAT commissioning process, and useful scientific data will start to come online through 2017. All MeerTime data will ultimately be made available for public use, and any published results will include the arrival times and profiles used in the results