Tessier number 30 clefts with congenital heart defects

Introduction: Midline cleft of mandible, classified as Tessier 30 clefts is extremely rare, with less than 100 reported cases in the latest studies. Variations in severity and associated malformations have been reported before. Case Presentation: In this report, we present the first documented Iranian case of Tessier 30 with median cleft of lower lip and bifid tongue concomitant with congenital heart defects. Conclusions: We explain embryologic origin, differential diagnosis, other associated anomalies and its treatment by reviewing literature. © 2015, Iranian Red Crescent Medical Journal

Area Invariance of Apparent Horizons under Arbitrary Boosts

It is a well known analytic result in general relativity that the 2-dimensional area of the apparent horizon of a black hole remains invariant regardless of the motion of the observer, and in fact is independent of the $t=constant$ slice, which can be quite arbitrary in general relativity. Nonetheless the explicit computation of horizon area is often substantially more difficult in some frames (complicated by the coordinate form of the metric), than in other frames. Here we give an explicit demonstration for very restricted metric forms of (Schwarzschild and Kerr) vacuum black holes. In the Kerr-Schild coordinate expression for these spacetimes they have an explicit Lorentz-invariant form. We consider {\it boosted} versions with the black hole moving through the coordinate system. Since these are stationary black hole spacetimes, the apparent horizons are two dimensional cross sections of their event horizons, so we compute the areas of apparent horizons in the boosted space with (boosted) $t = constant$, and obtain the same result as in the unboosted case. Note that while the invariance of area is generic, we deal only with black holes in the Kerr-Schild form, and consider only one particularly simple change of slicing which amounts to a boost. Even with these restrictions we find that the results illuminate the physics of the horizon as a null surface and provide a useful pedagogical tool. As far as we can determine, this is the first explicit calculation of this type demonstrating the area invariance of horizons. Further, these calculations are directly relevant to transformations that arise in computational representation of moving black holes. We present an application of this result to initial data for boosted black holes.Comment: 19 pages, 3 figures. Added a new section and 2 plots along with a coautho

The Race Between Stars and Quasars in Reionizing Cosmic Hydrogen

The cosmological background of ionizing radiation has been dominated by quasars once the Universe aged by ~2 billion years. At earlier times (redshifts z>3), the observed abundance of bright quasars declined sharply, implying that cosmic hydrogen was reionized by stars instead. Here, we explain the physical origin of the transition between the dominance of stars and quasars as a generic feature of structure formation in the concordance LCDM cosmology. At early times, the fraction of baryons in galaxies grows faster than the maximum (Eddington-limited) growth rate possible for quasars. As a result, quasars were not able to catch up with the rapid early growth of stellar mass in their host galaxies.Comment: 5 pages, 1 figure, Accepted for publication in JCA

Measuring the spin of the primary black hole in OJ287

The compact binary system in OJ287 is modelled to contain a spinning primary black hole with an accretion disk and a non-spinning secondary black hole. Using Post Newtonian (PN) accurate equations that include 2.5PN accurate non-spinning contributions, the leading order general relativistic and classical spin-orbit terms, the orbit of the binary black hole in OJ287 is calculated and as expected it depends on the spin of the primary black hole. Using the orbital solution, the specific times when the orbit of the secondary crosses the accretion disk of the primary are evaluated such that the record of observed outbursts from 1913 up to 2007 is reproduced. The timings of the outbursts are quite sensitive to the spin value. In order to reproduce all the known outbursts, including a newly discovered one in 1957, the Kerr parameter of the primary has to be $0.28 \pm 0.08$. The quadrupole-moment contributions to the equations of motion allow us to constrain the `no-hair' parameter to be $1.0\:\pm\:0.3$ where 0.3 is the one sigma error. This supports the `black hole no-hair theorem' within the achievable precision. It should be possible to test the present estimate in 2015 when the next outburst is due. The timing of the 2015 outburst is a strong function of the spin: if the spin is 0.36 of the maximal value allowed in general relativity, the outburst begins in early November 2015, while the same event starts in the end of January 2016 if the spin is 0.2Comment: 12 pages, 6 figure

Production of the virus-like particles of nipah virus matrix protein in Pichia pastoris as diagnostic reagents

The matrix (M) protein of Nipah virus (NiV) is a peripheral protein that plays a vital role in the envelopment of nucleocapsid protein and acts as a bridge between the viral surface and the nucleocapsid proteins. The M protein is also proven to play an important role in production of virus-like particles (VLPs) and is essential for assembly and budding of NiV particles. The recombinant M protein produced in Escherichia coli assembled into VLPs in the absence of the viral surface proteins. However, the E. coli produced VLPs are smaller than the native virus particles. Therefore, the aims of this study were to produce NiV M protein in Pichia pastoris, to examine the structure of the VLPs formed, and to assess the potential of the VLPs as a diagnostic reagent. The M protein was successfully expressed in P. pastoris and was detected with anti-myc antibody using Western blotting. The VLPs formed by the recombinant M protein were purified with sucrose density gradient ultracentrifugation, high-performance liquid chromatography (HPLC), and Immobilized Metal Affinity Chromatography (IMAC). Immunogold staining and transmission electron microscopy confirmed that the M protein assembled into VLPs as large as 200 nm. ELISA revealed that the NiV M protein produced in P. pastoris reacted strongly with positive NiV sera demonstrating its potential as a diagnostic reagent

Leaving the ISCO: the inner edge of a black-hole accretion disk at various luminosities

The "radiation inner edge" of an accretion disk is defined as the inner boundary of the region from which most of the luminosity emerges. Similarly, the "reflection edge" is the smallest radius capable of producing a significant X-ray reflection of the fluorescent iron line. For black hole accretion disks with very sub-Eddington luminosities these and all other "inner edges" locate at ISCO. Thus, in this case, one may rightly consider ISCO as the unique inner edge of the black hole accretion disk. However, even for moderate luminosities, there is no such unique inner edge as differently defined edges locate at different places. Several of them are significantly closer to the black hole than ISCO. The differences grow with the increasing luminosity. For nearly Eddington luminosities, they are so huge that the notion of the inner edge losses all practical significance.Comment: 12 pages, 15 figures, submitted to A&

Orbital resonances in discs around braneworld Kerr black holes

Rotating black holes in the brany universe of the Randall-Sundrum type are described by the Kerr geometry with a tidal charge b representing the interaction of the brany black hole and the bulk spacetime. For b<0 rotating black holes with dimensionless spin a>1 are allowed. We investigate the role of the tidal charge b in the orbital resonance model of QPOs in black hole systems. The orbital Keplerian, the radial and vertical epicyclic frequencies of the equatorial, quasicircular geodetical motion are given and their radial profiles are discussed. The resonant conditions are given in three astrophysically relevant situations: for direct (parametric) resonances, for the relativistic precession model, and for some trapped oscillations of the warped discs, with resonant combinational frequencies. It is shown, how b could influence matching of the observational data indicating the 3:2 frequency ratio observed in GRS 1915+105 microquasar with prediction of the orbital resonance model; limits on allowed range of the black hole parameters a and b are established. The "magic" dimensionless black hole spin enabling presence of strong resonant phenomena at the radius where \nu_K:\nu_{\theta}:\nu_r=3:2:1 is determined in dependence on b. Such strong resonances could be relevant even in sources with highly scattered resonant frequencies, as those expected in Sgr A*. The specific values of a and b are given also for existence of specific radius where \nu_K:\nu_{\theta}:\nu_r=s:t:u with 5>=s>t>u being small natural numbers. It is shown that for some ratios such situation is impossible in the field of black holes. We can conclude that analysing the microquasars high-frequency QPOs in the framework of orbital resonance models, we can put relevant limits on the tidal charge of brany Kerr black holes.Comment: 31 pages, 19 figures, to appear in General Relativity and Gravitatio

Can accretion disk properties distinguish gravastars from black holes?

Gravastars, hypothetic astrophysical objects, consisting of a dark energy condensate surrounded by a strongly correlated thin shell of anisotropic matter, have been proposed as an alternative to the standard black hole picture of general relativity. Observationally distinguishing between astrophysical black holes and gravastars is a major challenge for this latter theoretical model. In the context of stationary and axially symmetrical geometries, a possibility of distinguishing gravastars from black holes is through the comparative study of thin accretion disks around rotating gravastars and Kerr-type black holes, respectively. In the present paper, we consider accretion disks around slowly rotating gravastars, with all the metric tensor components estimated up to the second order in the angular velocity. Due to the differences in the exterior geometry, the thermodynamic and electromagnetic properties of the disks (energy flux, temperature distribution and equilibrium radiation spectrum) are different for these two classes of compact objects, consequently giving clear observational signatures. In addition to this, it is also shown that the conversion efficiency of the accreting mass into radiation is always smaller than the conversion efficiency for black holes, i.e., gravastars provide a less efficient mechanism for converting mass to radiation than black holes. Thus, these observational signatures provide the possibility of clearly distinguishing rotating gravastars from Kerr-type black holes.Comment: 12 pages, 12 figures. V2: 14 pages, significant discussion and references added, to appear in Class.Quant.Gra

Black Hole Spin via Continuum Fitting and the Role of Spin in Powering Transient Jets

The spins of ten stellar black holes have been measured using the continuum-fitting method. These black holes are located in two distinct classes of X-ray binary systems, one that is persistently X-ray bright and another that is transient. Both the persistent and transient black holes remain for long periods in a state where their spectra are dominated by a thermal accretion disk component. The spin of a black hole of known mass and distance can be measured by fitting this thermal continuum spectrum to the thin-disk model of Novikov and Thorne; the key fit parameter is the radius of the inner edge of the black hole's accretion disk. Strong observational and theoretical evidence links the inner-disk radius to the radius of the innermost stable circular orbit, which is trivially related to the dimensionless spin parameter a_* of the black hole (|a_*| < 1). The ten spins that have so far been measured by this continuum-fitting method range widely from a_* \approx 0 to a_* > 0.95. The robustness of the method is demonstrated by the dozens or hundreds of independent and consistent measurements of spin that have been obtained for several black holes, and through careful consideration of many sources of systematic error. Among the results discussed is a dichotomy between the transient and persistent black holes; the latter have higher spins and larger masses. Also discussed is recently discovered evidence in the transient sources for a correlation between the power of ballistic jets and black hole spin.Comment: 30 pages. Accepted for publication in Space Science Reviews. Also to appear in hard cover in the Space Sciences Series of ISSI "The Physics of Accretion onto Black Holes" (Springer Publisher). Changes to Sections 5.2, 6.1 and 7.4. Section 7.4 responds to Russell et al. 2013 (MNRAS, 431, 405) who find no evidence for a correlation between the power of ballistic jets and black hole spi

Long XMM observation of the Narrow-Line Seyfert 1 galaxy IRAS13224-3809: rapid variability, high spin and a soft lag

Results are presented from a 500ks long XMM-Newton observation of the Narrow-Line Seyfert 1 galaxy IRAS13224-3809. The source is rapidly variable on timescales down to a few 100s. The spectrum shows strong broad Fe-K and L emission features which are interpreted as arising from reflection from the inner parts of an accretion disc around a rapidly spinning black hole. Assuming a power-law emissivity for the reflected flux and that the innermost radius corresponds to the innermost stable circular orbit, the black hole spin is measured to be 0.988 with a statistical precision better than one per cent. Systematic uncertainties are discussed. A soft X-ray lag of 100s confirms this scenario. The bulk of the power-law continuum source is located at a radius of 2-3 gravitational radii.Comment: 7 pages, 14 figures, submitted to MNRA