605 research outputs found
Development of Hemic Neoplasia in the Soft-Shell Clam (Mya arenaria) Along the East Coast of the United States
- Author
- Publication venue
- Digital Commons @ West Chester University
- Publication date
- 01/01/2022
- Field of study
Hemic neoplasia (HN) is a bivalve disease characterized by uncontrolled proliferation of abnormal hemocytes that invade solid tissue, similar to vertebrate leukemia, ultimately leading to death. High disease prevalence has been reported in many bivalve populations, yet disease etiology and development remain minimally understood. In this study, nine East Coast populations of soft-shell clams (Mya arenaria) were evaluated between 2011-2012 to identify environmental and health factors associated with HN. PCA analysis and statistical testing were used to compare data at and between each population based on HN status. The percentage of organisms with terminal stage 4 HN (76-100% neoplastic cells) was used to group sites into those of high and low disease incidence; with average terminal HN of 6.46% and 28.15% and organismal survival of 60.8% and 20.2% detected for low and high HN sites, respectively. Analysis revealed pollutants including PCBs (Aroclor 1221), PAHs (pyrene and fluoranthene), organochlorinated pesticides (methoxychlor, toxaphene, endrin, BHCs, aldrin, Endosulfan, and heptachlor) and heavy metals (iron, aluminum, chromium, copper, nickel, and zinc); as well as sediment organic content were strongly associated with HN prevalence and survival. On average, high HN sites displayed 1422 mg/kg total pollutants and 49.2% organic content, while low HN sites displayed 388 mg/kg and 36.5%, respectively. Water temperature was also associated with HN and mortality, emphasizing concerns about rising ocean temperatures associated with climate change. Overall, higher pollutant levels or elevated water temperatures increased HN incidence indicating disease transmission through viral infection is likely due to reduced immunity in M. arenaria
A critical evaluation of loss of heterozygosity detected in tumor tissues, blood serum and bone marrow plasma from patients with breast cancer
- Author
- B Taback
- B Taback
- CL Wu
- Cord Beeger
- D Niederacher
- F Coulet
- FKH Chun
- G Sourvinos
- H Nawroz
- H Schwarzenbach
- H Schwarzenbach
- Heidi Schwarzenbach
- HX An
- I Müller
- JH Lichy
- JM Silva
- JM Silva
- JM Silva
- K Driouch
- K Hibi
- K Pantel
- K Pantel
- K Yoshida
- Klaus Pantel
- M Colozza
- M Koldehoff
- M Nessling
- M Stroun
- M Stroun
- Miriam Gottberg
- MR Stratton
- MS Kopreski
- MW Beckmann
- Nicole Stahmann
- P Anker
- P Iniesta
- P O'Connell
- P Rimessi
- Q Wang
- QX Zhang
- RDG Dahiya
- RG Dumitrescu
- S Ingvarsson
- S Jahr
- S Seitz
- U Hannelius
- V Müller
- Volkmar Müller
- W Janni
- W Remmele
- X Yang
- XQ Chen
- Publication venue
- BioMed Central
- Publication date
- Field of study
Parallel Alterations of Functional Connectivity during Execution and Imagination after Motor Imagery Learning
- Author
- A Battaglia Mayer
- A Guillot
- A Isaac
- A Parkinson
- A Solodkin
- AD Lawrence
- AM Kelly
- B Haslinger
- C Büchel
- CH Kasess
- CR Hall
- CR Li
- D Coynel
- DM Wolperts
- E Gerardin
- E Hoshi
- F Cauda
- FT Sun
- FT Sun
- G Albouy
- G Luppino
- G Prabhu
- H Alkadhi
- H Zhang
- Hang Zhang
- J Fernandez-Ruiz
- J Jastorff
- J Rissman
- K Arfanakis
- K Doya
- K Ogawa
- K Sakai
- KM Stephan
- L Fogassi
- L López
- Lele Xu
- LG Ungerleider
- Li Yao
- LQ Uddin
- M Argyelan
- M Behrmann
- M Lotze
- M Lotze
- M Matelli
- MF Lafleur
- MG Lacourse
- Mingqi Hui
- MK Fleming
- MV Chafee
- N Hattori
- N Sharma
- N Wenderoth
- Nicole Wenderoth
- O Hikosaka
- P Dechent
- P Haggard
- P Peigneux
- P Soliveri
- PL Jackson
- RA Schmidt
- RA Schmidt
- RJ Seitz
- RS Johansson
- Rushao Zhang
- S Rozzi
- SS Kantak
- T Hanakawa
- T Jiang
- Xiaojie Zhao
- Zhiying Long
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
BACKGROUND: Neural substrates underlying motor learning have been widely investigated with neuroimaging technologies. Investigations have illustrated the critical regions of motor learning and further revealed parallel alterations of functional activation during imagination and execution after learning. However, little is known about the functional connectivity associated with motor learning, especially motor imagery learning, although benefits from functional connectivity analysis attract more attention to the related explorations. We explored whether motor imagery (MI) and motor execution (ME) shared parallel alterations of functional connectivity after MI learning. METHODOLOGY/PRINCIPAL FINDINGS: Graph theory analysis, which is widely used in functional connectivity exploration, was performed on the functional magnetic resonance imaging (fMRI) data of MI and ME tasks before and after 14 days of consecutive MI learning. The control group had no learning. Two measures, connectivity degree and interregional connectivity, were calculated and further assessed at a statistical level. Two interesting results were obtained: (1) The connectivity degree of the right posterior parietal lobe decreased in both MI and ME tasks after MI learning in the experimental group; (2) The parallel alterations of interregional connectivity related to the right posterior parietal lobe occurred in the supplementary motor area for both tasks. CONCLUSIONS/SIGNIFICANCE: These computational results may provide the following insights: (1) The establishment of motor schema through MI learning may induce the significant decrease of connectivity degree in the posterior parietal lobe; (2) The decreased interregional connectivity between the supplementary motor area and the right posterior parietal lobe in post-test implicates the dissociation between motor learning and task performing. These findings and explanations further revealed the neural substrates underpinning MI learning and supported that the potential value of MI learning in motor function rehabilitation and motor skill learning deserves more attention and further investigation
Diving into the vertical dimension of elasmobranch movement ecology
- Author
- Abrantes Katya
- Afonso Andre S.
- Ajemian Matthew J.
- Anderson Brooke N.
- Anderson Scot D.
- Andrzejaczek Samantha
- Araujo Gonzalo
- Armstrong Amelia J.
- Armstrong Asia O.
- Bach Pascal
- Barnett Adam
- Bennett Mike B.
- Bezerra Natalia P. A.
- Block Barbara A.
- Bonfil Ramon
- Boustany Andre M.
- Bowlby Heather D.
- Branco Ilka
- Braun Carmin D.
- Brooks Edward J.
- Brown Judith
- Burke Patrick J.
- Butcher Paul
- Carlisle Aaron B
- Castleton Michael
- Chapple Taylor K
- Chateau Olivier
- Clarke Maurice
- Coelho Rui
- Coffey Daniel M.
- Cortes Enric
- Couturier Lydie I. E.
- Cowley Paul D.
- Croll Donald A.
- Cuevas Juan M.
- Curnick David J.
- Curtis Tobey H.
- Dagorn Laurent
- Dale Jonathan J.
- Daly Ryan
- Dewar Heidi
- Doherty Philip D.
- Domingo Andres
- Dove Alistair D. M.
- Drew Michael
- Dudgeon Christine L.
- Duffy Clinton A. J.
- Elliott Riley G.
- Ellis Jim R.
- Erdmann Mark V.
- Farrugia Thomas J.
- Ferreira Luciana C
- Ferretti Francesco
- Filmalter John D
- Finucci Brittany
- Fischer Chris
- Fitzpatrick Richard
- Forget Fabien
- Forsberg Kerstin
- Francis Malcolm P.
- Franks Bryan R.
- Gallagher Austin J.
- Galva-Magana Felipe
- Garcia Mirta L.
- Gaston Troy F.
- Gillanders Bronwyn M.
- Gleiss Adrian C.
- Gollock Matthew J
- Goodman Maurice C.
- Green Jonathan R.
- Green Sofia
- Griffiths Christopher A.
- Hammerschlag Neil
- Hasan Abdi
- Hawkes Lucy A.
- Hazin Fabio H.V.
- Heard Matthew
- Hearn Alex
- Henderson Suzanne M.
- Holdsworth John C
- Holland Kim N.
- Howey Lucy A.
- Hueter Robert E.
- Humphries Nicolas E.
- Hussey Nigel E
- Hutchinson Melanie
- Huveneers Charlie
- Jacoby David M. P.
- Jaine Fabrice R. A.
- Jorgensen Salvador J.
- Kanive Paul E.
- Labaja Jessica
- Lana Fernanda O.
- Lassauce Hugo
- Lipscombe Rebecca S.
- Llewellyn Fiona
- Lucas Tim C. D.
- Macena Bruno C. L.
- Mambrasar Ronald
- McAllister Jaime D
- McCully Phillips Sophy R.
- McGregor Frazer
- McMillan Matthew N.
- McNaughton Lianne M.
- Meekan Mark G
- Mendonça Sibele A.
- Meyer Carl G.
- Meyers Megan
- Mohan John A.
- Montgomery John C.
- Mourier Johann
- Mucientes Gonzalo
- Musyl Michael K.
- Nasby-Lucas Nicole
- Natanson Lisa
- O\u27Sullivan John B.
- Oliveira Paulo
- Papastamatiou Yannis P
- Patterson Toby A.
- Peel Lauren R.
- Pierce Simon J.
- Queiroz Nuno
- Radford Craig A.
- Richardson Andy J.
- Richardson Anthony J.
- Righton David
- Rohner Christoph A
- Royer Mark A.
- Saunders Ryan A.
- Schaber Matthias
- Schallert Robert J.
- Scholl Michael C.
- Seitz Andrew C.
- Semmens Jayson M
- Setyawan Edy
- Shea Brendan D.
- Shidqi Rafid A.
- Shillinger George
- Shipley Oliver N.
- Shivji Mahmood
- Sianipar Abraham B.
- Silva Joana F.
- Sims David W.
- Skomal Gregory B
- Sousa Lara L.
- Southall Emily J
- Spaet Julia L. Y.
- Stehfest Killian M.
- Stevens Guy
- Stewart Joshua D.
- Sulikowski James
- Syakurachman Ismail
- Thorrold Simon R
- Thums Michele
- Tickler David
- Tolloti Mariana T.
- Townsend Kathy A.
- Travassos Paulo
- Tyminski John P
- Vaudo Jeremy
- Veras Drausio
- Wantiez Laurent
- Weber Sam B.
- Wells R.J. David
- Weng Kevin C.
- Wetherbee Bradley M.
- Williamson Jane E.
- Witt Matthew J.
- Wright Serena
- Zilliacus Kelly
- Publication venue
- NSUWorks
- Publication date
- 19/08/2022
- Field of study
Knowledge of the three-dimensional movement patterns of elasmobranchs is vital to understand their ecological roles and exposure to anthropogenic pressures. To date, comparative studies among species at global scales have mostly focused on horizontal movements. Our study addresses the knowledge gap of vertical movements by compiling the first global synthesis of vertical habitat use by elasmobranchs from data obtained by deployment of 989 biotelemetry tags on 38 elasmobranch species. Elasmobranchs displayed high intra- and interspecific variability in vertical movement patterns. Substantial vertical overlap was observed for many epipelagic elasmobranchs, indicating an increased likelihood to display spatial overlap, biologically interact, and share similar risk to anthropogenic threats that vary on a vertical gradient. We highlight the critical next steps toward incorporating vertical movement into global management and monitoring strategies for elasmobranchs, emphasizing the need to address geographic and taxonomic biases in deployments and to concurrently consider both horizontal and vertical movements
Diving into the vertical dimension of elasmobranch movement ecology
- Author
- Abrantes Katya
- Afonso Andre S.
- Ajemian Matthew J.
- Anderson Brooke N.
- Anderson Scot D.
- Andrzejaczek Samantha
- Araujo Gonzalo
- Armstrong Amelia J.
- Armstrong Asia O.
- Bach Pascal
- Barnett Adam
- Bennett Mike B.
- Bezerra Natalia A.
- Block Barbara A.
- Boustany Andre M.
- Bowlby Heather D.
- Branco Ilka
- Braun Camrin D.
- Brooks Edward J.
- Burke Patrick J.
- Butcher Paul
- Carlisle Aaron
- Castleton Michael
- Chapple Taylor K.
- Clarke Maurice
- Coelho Rui
- Cortes Enric
- Couturier Lydie I. E.
- Cowley Paul D.
- Croll Donald A.
- Cuevas Juan M.
- Curnick David J.
- Curtis Tobey H.
- Dagorn Laurent
- Dale Jonathan J.
- Daly Ryan
- Dewar Heidi
- Doherty Philip D.
- Domingo Andres
- Dove Alistair D. M.
- Drew Michael
- Dudgeon Christine L.
- Duffy Clinton A. J.
- Elliott Riley G.
- Ellis Jim R.
- Erdmann Mark
- Farrugia Thomas J.
- Ferreira Luciana C.
- Ferretti Francesco
- Filmalter John D.
- Finucci Brittany
- Fischer Chris
- Fitzpatrick Richard
- Forget Fabien
- Forsberg Kerstin
- Francis Malcolm P.
- Franks Bryan R.
- Gallagher Austin J.
- Galvan-Magana Felipe
- Garcia Mirta L.
- Gaston Troy F.
- Gillanders Bronwyn M.
- Gleiss Adrian C.
- Gollock Matthew J.
- Goodman Maurice C.
- Green Jonathan R.
- Green Sofia
- Griffiths Christopher
- Hammerschlag Neil
- Hasan Abdi
- Hawkes Lucy A.
- Hazin Fabio
- Heard Matthew
- Hearn Alex
- Hedges Kevin J.
- Henderson Suzanne M.
- Holdsworth John
- Holland Kim N.
- Howey Lucy A.
- Hueter Robert E.
- Humphries Nicholas E.
- Hussey Nigel E.
- Hutchinson Melanie
- Huveneers Charlie
- Jacoby David M. P.
- Jaine Fabrice R. A.
- Jorgensen Salvador J.
- Kanive Paul E.
- Labaja Jessica
- Lana Fernanda O.
- Lassauce Hugo
- Lipscombe Rebecca S.
- Llewellyn Fiona
- Lucas Tim C. D.
- Macena Bruno C. L.
- Mambrasar Ronald
- McAllister Jaime D.
- McGregor Frazer
- McMillan Matthew N.
- McNaughton Lianne M.
- Meekan Mark G.
- Mendonca Sibele A.
- Meyer Carl G.
- Meyers Megan
- Mohan John A.
- Montgomery John C.
- Mourier Johann
- Mucientes Gonzalo
- Musyl Michael K.
- Nasby-Lucas Nicole
- Natanson Lisa J.
- O'Sullivan John B.
- Oliveira Paulo
- Papastamtiou Yannis P.
- Patterson Toby A.
- Phillips Sophy R. McCully
- Pierce Simon J.
- Queiroz Nuno
- Radford Craig A.
- Richardson Anthony J.
- Righton David
- Rohner Christoph A.
- Royer Mark A.
- Saunders Ryan A.
- Schaber Matthias
- Schallert Robert J.
- Scholl Michael C.
- Seitz Andrew C.
- Semmens Jayson M.
- Setyawan Edy
- Shea Brendan D.
- Shidqi Rafid A.
- Shillinger George L.
- Shipley Oliver N.
- Shivji Mahmood S.
- Sianipar Abraham B.
- Silva Joana F.
- Sims David W.
- Skomal Gregory B.
- Sousa Lara L.
- Southall Emily J.
- Spaet Julia L. Y.
- Stehfest Kilian M.
- Stewart Joshua D.
- Sulikowski James A.
- Syakurachman Ismail
- Thorrold Simon R.
- Thums Michele
- Tickler David
- Tolloti Mariana T.
- Townsend Kathy A.
- Travassos Paulo
- Tyminski John P.
- Vaudo Jeremy J.
- Veras Drausio
- Wantiez Laurent
- Weber Sam B.
- Wells R. J. David
- Weng Kevin C.
- Wetherbee Bradley M.
- Williamson Jane E.
- Witt Matthew J.
- Wright Serena
- Zilliacus Kelly
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Knowledge of the three-dimensional movement patterns of elasmobranchs is vital to understand their ecological roles and exposure to anthropogenic pressures. To date, comparative studies among species at global scales have mostly focused on horizontal movements. Our study addresses the knowledge gap of vertical movements by compiling the first global synthesis of vertical habitat use by elasmobranchs from data obtained by deployment of 989 biotelemetry tags on 38 elasmobranch species. Elasmobranchs displayed high intra- and interspecific variability in vertical movement patterns. Substantial vertical overlap was observed for many epipelagic elasmobranchs, indicating an increased likelihood to display spatial overlap, biologically interact, and share similar risk to anthropogenic threats that vary on a vertical gradient. We highlight the critical next steps toward incorporating vertical movement into global management and monitoring strategies for elasmobranchs, emphasizing the need to address geographic and taxonomic biases in deployments and to concurrently consider both horizontal and vertical movements
The Human Phenotype Ontology in 2024: phenotypes around the world.
- Author
- Addo-Lartey Eunice B
- Anagnostopoulos Anna V
- Anderton Joel
- Avillach Paul
- Bagley Anita M
- Bakštein Eduard
- Balhoff James P
- Baynam Gareth
- Bello Susan M
- Berk Michael
- Bertram Holli
- Bishop Somer
- Blau Hannah
- Bodenstein David F
- Botas Pablo
- Boztug Kaan
- Callahan Tiffany J
- Cameron Rhiannon
- Carbon Seth J
- Carmody Leigh
- Castellanos Francisco
- Caufield J Harry
- Chan Lauren E
- Chute Christopher G
- Coleman Ben D
- Cruz-Rojo Jaime
- Dahan-Oliel Noémi
- Danis Daniel
- Davids Jon R
- de Dieuleveult Maud
- de Souza Vinicius
- de Vries Bert B A
- de Vries Esther
- DePaulo J Raymond
- Derfalvi Beata
- Dhombres Ferdinand
- Diaz-Byrd Claudia
- Dingemans Alexander J M
- Donadille Bruno
- Duyzend Michael
- Elfeky Reem
- Essaid Shahim
- Fabrizzi Carolina
- Fico Giovanna
- Firth Helen V
- Freudenberg-Hua Yun
- Fullerton Janice M
- Gabriel Davera L
- Gargano Michael
- Gilmour Kimberly
- Giordano Jessica
- Goes Fernando S
- Green Ian
- Griese Matthias
- Groza Tudor
- Gu Weihong
- Guthrie Julia
- Gyori Benjamin
- Haendel Melissa A
- Hamosh Ada
- Hanauer Marc
- Hanušová Kateřina
- Harris Nomi L
- He Yongqun Oliver
- Hegde Harshad
- Helbig Ingo
- Holasová Kateřina
- Hoyt Charles Tapley
- Huang Shangzhi
- Hurwitz Eric
- Jacobsen Julius O B
- Jiang Xiaofeng
- Joseph Lisa
- Keramatian Kamyar
- King Bryan
- Knoflach Katrin
- Koolen David A
- Kraus Megan L
- Kroll Carlo
- Kusters Maaike
- Köhler Sebastian
- Ladewig Markus S
- Lagorce David
- Lai Meng-Chuan
- Lapunzina Pablo
- Laraway Bryan
- Lewis-Smith David
- Li Xiarong
- Lucano Caterina
- Majd Marzieh
- Marazita Mary L
- Martinez-Glez Victor
- Matentzoglu Nicolas
- McHenry Toby H
- McInnis Melvin G
- McMurry Julie A
- Mihulová Michaela
- Millett Caitlin E
- Mitchell Philip B
- Moses Rachel Gore
- Moslerová Veronika
- Mungall Christopher J
- Munoz-Torres Monica C
- Narutomi Kenji
- Nematollahi Shahrzad
- Nevado Julian
- Nierenberg Andrew A
- Nurnberger John I
- Ogishima Soichi
- Olson Daniel
- Ortiz Abigail
- Pachajoa Harry
- Perez de Nanclares Guiomar
- Peters Amy
- Putman Tim
- Rapp Christina K
- Rath Ana
- Reese Justin
- Rekerle Lauren
- Roberts Angharad M
- Robinson Peter N
- Roy Suzy
- Sanders Stephan J
- Schuetz Catharina
- Schulte Eva C
- Schulze Thomas G
- Schwarz Martin
- Scott Katie
- Seelow Dominik
- Seitz Berthold
- Shen Yiping
- Similuk Morgan N
- Simon Eric S
- Singh Balwinder
- Smedley Damian
- Smith Cynthia
- Smolinsky Jake T
- Sperry Sarah
- Stafford Elizabeth
- Stefancsik Ray
- Steinhaus Robin
- Strawbridge Rebecca
- Sundaramurthi Jagadish Chandrabose
- Talapova Polina
- Tenorio Castano Jair A
- Tesner Pavel
- Thomas Rhys H
- Thurm Audrey
- Toro Sabrina
- Turnovec Marek
- van Gijn Marielle E
- Vasilevsky Nicole A
- Vlčková Markéta
- Walden Anita
- Wang Kai
- Wapner Ron
- Ware James S
- Wiafe Addo A
- Wiafe Samuel A
- Wiggins Lisa D
- Williams Andrew E
- Wu Chen
- Wyrwoll Margot J
- Xiong Hui
- Yalin Nefize
- Yamamoto Yasunori
- Yatham Lakshmi N
- Yocum Anastasia K
- Young Allan H
- Yüksel Zafer
- Zandi Peter P
- Zankl Andreas
- Zarante Ignacio
- Zvolský Miroslav
- Čady Jolana
- Čajbiková Nikola Novák
- Publication venue
- The Mouseion at the JAXlibrary
- Publication date
- 01/01/2024
- Field of study
The Human Phenotype Ontology (HPO) is a widely used resource that comprehensively organizes and defines the phenotypic features of human disease, enabling computational inference and supporting genomic and phenotypic analyses through semantic similarity and machine learning algorithms. The HPO has widespread applications in clinical diagnostics and translational research, including genomic diagnostics, gene-disease discovery, and cohort analytics. In recent years, groups around the world have developed translations of the HPO from English to other languages, and the HPO browser has been internationalized, allowing users to view HPO term labels and in many cases synonyms and definitions in ten languages in addition to English. Since our last report, a total of 2239 new HPO terms and 49235 new HPO annotations were developed, many in collaboration with external groups in the fields of psychiatry, arthrogryposis, immunology and cardiology. The Medical Action Ontology (MAxO) is a new effort to model treatments and other measures taken for clinical management. Finally, the HPO consortium is contributing to efforts to integrate the HPO and the GA4GH Phenopacket Schema into electronic health records (EHRs) with the goal of more standardized and computable integration of rare disease data in EHRs
Diving into the vertical dimension of elasmobranch movement ecology
- Author
- Afonso Andre S.
- Ajemian Matthew J.
- Anderson Brooke N.
- Anderson Scot D.
- Andrzejaczek Samantha
- Araujo Gonzalo
- Armstrong Amelia J.
- Armstrong Asia O.
- Bach Pascal
- Barnett Adam
- Bennett Mike B.
- Bezerra Natalia A.
- Block Barbara A.
- Bonfil Ramon
- Boustany Andre M.
- Bowlby Heather D.
- Branco Ilka
- Braun Camrin D.
- Brooks Edward J.
- Brown Judith
- Burke Patrick J.
- Butcher Paul
- Carlisle Aaron
- Castleton Michael
- Chapple Taylor K.
- Chateau Olivier
- Clarke Maurice
- Coelho Rui
- Coffey Daniel M.
- Cortes Enric
- Couturier Lydie I. E.
- Cowley Paul D.
- Croll Donald A.
- Cuevas Juan M.
- Curnick David J.
- Curtis Tobey H.
- Dagorn Laurent
- Dale Jonathan J.
- Daly Ryan
- Dewar Heidi
- Doherty Philip D.
- Domingo Andres
- dos Santos Abrantes Katya
- Dove Alistair D. M.
- Drew Michael
- Dudgeon Christine L.
- Duffy Clinton A. J.
- Elliott Riley G.
- Ellis Jim R.
- Erdmann Mark
- Farrugia Thomas J.
- Ferreira Luciana C.
- Ferretti Francesco
- Filmalter John D.
- Finucci Brittany
- Fischer Chris
- Fitzpatrick Richard
- Forget Fabien
- Forsberg Kerstin
- Francis Malcolm P.
- Franks Bryan R.
- Gallagher Austin J.
- Galvan-Magana Felipe
- Garcia Mirta L.
- Gaston Troy F.
- Gillanders Bronwyn M.
- Gleiss Adrian C.
- Gollock Matthew J.
- Goodman Maurice C.
- Green Jonathan R.
- Green Sofia
- Griffiths Christopher A.
- Hammerschlag Neil
- Hasan Abdi
- Hawkes Lucy A.
- Hazin Fabio
- Heard Matthew
- Hearn Alex
- Hedges Kevin J.
- Henderson Suzanne M.
- Holdsworth John
- Holland Kim N.
- Howey Lucy A.
- Hueter Robert E.
- Humphries Nicholas E.
- Hussey Nigel E.
- Hutchinson Melanie
- Huveneers Charlie
- Jacoby David M.P.
- Jaine Fabrice R. A.
- Jorgensen Salvador J.
- Kanive Paul E.
- Labaja Jessica
- Lana Fernanda O.
- Lassauce Hugo
- Lipscombe Rebecca S.
- Llewellyn Fiona
- Lucas Tim. C.D.
- Macena Bruno C. L.
- Mambrasar Ronald
- McAllister Jaime D.
- McGregor Frazer
- McMillan Matthew N.
- McNaughton Lianne M.
- Meekan Mark G.
- Mendonca Sibele A.
- Meyer Carl G.
- Meyers Megan
- Mohan John A.
- Montgomery John C.
- Mourier Johann
- Mucientes Gonzalo
- Musyl Michael K.
- Nasby-Lucas Nicole
- Natanson Lisa J.
- O'Sullivan John B.
- Oliveira Paulo
- Papastamtiou Yannis P.
- Patterson Toby A.
- Peel Lauren R.
- Phillips Sophy R. McCully
- Pierce Simon J.
- Queiroz Nuno
- Radford Craig A.
- Richardson Andy J.
- Richardson Anthony J.
- Righton David
- Rohner Christoph A.
- Royer Mark A.
- Saunders Ryan A.
- Schaber Matthias
- Schallert Robert J.
- Scholl Michael C.
- Seitz Andrew C.
- Semmens Jayson M.
- Setyawan Edy
- Shea Brendan D.
- Shidqi Rafid A.
- Shillinger George L.
- Shipley Oliver N.
- Shivji Mahmood S.
- Sianipar Abraham B.
- Silva Joana F.
- Sims David W.
- Skomal Gregory B.
- Sousa Lara L.
- Southall Emily J.
- Spaet Julia L. Y.
- Stehfest Kilian M.
- Stevens Guy
- Stewart Joshua D.
- Sulikowski James A.
- Syakurachman Ismail
- Thorrold Simon R.
- Thums Michele
- Tickler David
- Tolloti Mariana T.
- Townsend Kathy A.
- Travassos Paulo
- Tyminski John P.
- Vaudo Jeremy J.
- Veras Drausio
- Wantiez Laurent
- Weber Sam B.
- Wells R. J. David
- Weng Kevin C.
- Wetherbee Bradley M.
- Williamson Jane E.
- Witt Matthew J.
- Wright Serena
- Zilliacus Kelly
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 01/01/2022
- Field of study
Knowledge of the three-dimensional movement patterns of elasmobranchs is vital to understand their ecological roles and exposure to anthropogenic pressures. To date, comparative studies among species at global scales have mostly focused on horizontal movements. Our study addresses the knowledge gap of vertical movements by compiling the first global synthesis of vertical habitat use by elasmobranchs from data obtained by deployment of 989 biotelemetry tags on 38 elasmobranch species. Elasmobranchs displayed high intra- and interspecific variability in vertical movement patterns. Substantial vertical overlap was observed for many epipelagic elasmobranchs, indicating an increased likelihood to display spatial overlap, biologically interact, and share similar risk to anthropogenic threats that vary on a vertical gradient. We highlight the critical next steps toward incorporating vertical movement into global management and monitoring strategies for elasmobranchs, emphasizing the need to address geographic and taxonomic biases in deployments and to concurrently consider both horizontal and vertical movements
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
- Author
- Abdellaoui Abdel
- Abramova Liliya
- Adams Mark
- Adams Mark J.
- Adan Roger A. H.
- Adolfsson Rolf
- Adolfsson Rolf
- Adorjan Kristina
- Agartz Ingrid
- Agartz Ingrid
- Agerbo Esben
- Agerbo Esben
- Agerbo Esben
- Aguayo Samuel
- Ahuja Sunil
- Air Tracy M.
- Air Tracy M.
- Al Eissa Mariam
- Albani Diego
- Alda Martin
- Alda Martin
- Alfredsson Lars
- Alfredsson Lars
- Alfredsson Lars
- Alliey-Rodriguez Ney
- Als Thomas D.
- Andlauer Till F. M.
- Ando Tetsuya
- Andreassen Ole A.
- Andreassen Ole A.
- Andreassen Ole A.
- Anjorin Adebayo
- Anjorin Adebayo
- Antilla Verneri
- Antoniou Anastasia
- Appadurai Vivek
- Argyres Dean P.
- Arolt Volker
- Artigas Maria Soler
- Aschauer Harald
- Ashley-Koch Allison E.
- Aslan Mihaela
- Awasthi Swapnil
- Awasthi Swapnil
- Awasthi Swapnil
- Azevedo M. Helena
- Babadjanova Gulja
- Bacanu Silviu-Alin
- Backlund Lena
- Baek Ji Hyun
- Baker Jessica H.
- Ballas Zuhair
- Bass Nicholas
- Bass Nicholas
- Bau Claiton H. D.
- Bauer Michael
- Baune Bernhard T.
- Baune Bernhard T.
- Baune Bernhard T.
- Beckham Jean
- Beckham Jean
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- Bellivier Frank
- Bencko Vladimir
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- Berger Klaus
- Berrettini Wade H.
- Berrettini Wade H.
- Berrettini Wade H.
- Bhushan Sujata
- Biernacka Joanna M.
- Biernacka Joanna M.
- Bigdeli Tim B.
- Bigdeli Tim B.
- Bigdeli Tim B.
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- Birgegård Andreas
- Birner Armin
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- Breeling James
- Breen Gerome
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- Sun Yan
- Szatkiewicz Jin P.
- Sánchez-Mora Cristina
- Sánchez-Mora Cristina
- Tachmazidou Ioanna
- Tandon Neeraj
- Tansey Katherine E.
- Teismann Henning
- Tenconi Elena
- Terao Chikashi
- Teumer Alexander
- Thompson Wesley
- Thomson Pippa A.
- Thorgeirsson Thorgeir E.
- Thorgeirsson Thorgeir E.
- Thornton Laura M.
- Thornton Laura M.
- Tiemeier Henning
- Toma Claudio
- Tooney Paul
- Tortorella Alfonso
- Tozzi Federica
- Traylor Matthew
- Treasure Janet
- Treasure Janet
- Treutlein Jens
- Treutlein Jens
- Trubetskoy Vassily
- Trubetskoy Vassily
- Trzaskowski Maciej
- Trzaskowski Maciej
- Tsao Philip
- Tsao Philip S.
- Tsao Philip S.
- Tsao Philip S.
- Tsermpini Evangelia-Eirini
- Tsitsika Artemis
- Tsuang Ming T.
- Turecki Gustavo
- Turecki Gustavo
- Tyszkiewicz-Nwafor Marta
- Tziouvas Konstantinos
- Uher Rudolf
- Uitterlinden André G.
- Umbricht Daniel
- Ursano Robert J.
- Vaaler Arne E.
- Van der Auwera Sandra
- van Elburg Annemarie A.
- van Furth Eric F.
- van Hemert Albert M.
- Vawter Marquis P.
- Vedder Helmut
- Vieta Eduard
- Viktorin Alexander
- Vilar-Ribó Laura
- Villareal Gerardo
- Vincent John B.
- Vincent John B.
- Visscher Peter M.
- Völzke Henry
- Völzke Henry
- Wade Tracey D.
- Wagner Gudrun
- Waldman Irwin D.
- Wallbom Agnes
- Walters James T. R.
- Walters James T. R.
- Walton Esther
- Wang Yunpeng
- Ware Erin B.
- Wasserman Danuta
- Watson Hunna J.
- Watson Hunna J.
- Webb Bradley T.
- Weickert Cynthia Shannon
- Weickert Thomas W.
- Weickert Thomas W.
- Weinsheimer Shantel Marie
- Weissman Myrna M.
- Weissman Myrna M.
- Wellmann Jürgen
- Werge Thomas
- Werge Thomas
- Werge Thomas
- Werge Thomas
- Whitbourne Stacey B.
- Whiteman David C.
- Whiteman David C.
- Whittle Jeffrey
- Whooley Mary
- Wichmann H. Erich
- Widen Elisabeth
- Willemsen Gonneke
- Williams Leanne M.
- Willour Virginia
- Wilson Peter
- Winsvold Bendik S.
- Witt Stephanie H.
- Witt Stephanie H.
- Witt Stephanie H.
- Witt Stephanie H.
- Won Hong-Hee
- Woodside D. Blake
- Woodside D. Blake
- Wray Naomi R.
- Wray Naomi R.
- Wray Naomi R.
- Wu Yang
- Xi Hualin S.
- Xi Simon
- Xu Junzhe
- Xu Wei
- Yang Jian
- Yao Shuyang
- Yeh Shing Shing
- Yilmaz Zeynep
- Yilmaz Zeynep
- Young Allan H.
- Young Hannah
- Zablocki Clement J.
- Zai Clement C.
- Zandi Peter P.
- Zeggini Eleftheria
- Zerwas Stephanie
- Zhang Futao
- Zhao Hongyu
- Zhou Hang
- Zillich Lea
- Zillich Lea
- Zipfel Stephan
- Zwart John-Anker
- Świątkowska Beata
- Świątkowska Beata
- Świątkowska Beata
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. Methods We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) cases and 519,961 controls in the International Suicide Genetics Consortium (ISGC). The GWAS of SA was conditioned on psychiatric disorders using GWAS summary statistics via multitrait-based conditional and joint analysis, to remove genetic effects on SA mediated by psychiatric disorders. We investigated the shared and divergent genetic architectures of SA, psychiatric disorders, and other known risk factors. Results Two loci reached genome-wide significance for SA: the major histocompatibility complex and an intergenic locus on chromosome 7, the latter of which remained associated with SA after conditioning on psychiatric disorders and replicated in an independent cohort from the Million Veteran Program. This locus has been implicated in risk-taking behavior, smoking, and insomnia. SA showed strong genetic correlation with psychiatric disorders, particularly major depression, and also with smoking, pain, risk-taking behavior, sleep disturbances, lower educational attainment, reproductive traits, lower socioeconomic status, and poorer general health. After conditioning on psychiatric disorders, the genetic correlations between SA and psychiatric disorders decreased, whereas those with nonpsychiatric traits remained largely unchanged. Conclusions Our results identify a risk locus that contributes more strongly to SA than other phenotypes and suggest a shared underlying biology between SA and known risk factors that is not mediated by psychiatric disorders.Peer reviewe
Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abdulsalam Abdulla
- Abercrombie Daniel
- Abu Zeid Shimaa
- Ackert Andrew
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Jordon Rowe
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Agapitos Antonis
- Aggleton Robin
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahmed Ijaz
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Al-bataineh Ayman
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- Aldá Júnior Walter Luiz
- Aleksandrov Aleksandar
- Alexakhin Vadim
- Alexander James
- Alimena Juliette
- Allen Brandon
- Almond John
- Alunni Solestizi Luisa
- Alverson George
- Alves Fábio Lúcio
- Alves Gilvan
- Alyari Maral
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Anderson Ian
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Anelli Christopher
- Antonelli Louis
- Antropov Iurii
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Askew Andrew
- Attikis Alexandros
- Aubin Alexandre
- Auffray Etiennette
- Autermann Christian
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Aşılar Ece
- Baarmand Marc M
- Baber Mark
- Bacchetta Nicola
- Bachmair Felix
- Bachtis Michail
- Baden Drew
- Baffioni Stephanie
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakhshiansohi Hamed
- Ball Austin
- Ball Fionn
- Ban Yong
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Barbieri Richard
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Baron Owen
- Barone Luciano
- Barria Patrizia
- Barrio Luna Mar
- Bartek Rachel
- Barth Christian
- Bartosik Nazar
- Bartók Márton
- Baskakov Alexey
- Battilana Carlo
- Baty Austin
- Bauerdick Lothar AT
- Baumgartel Darin
- Baus Colin
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beck Lana
- Beernaert Kelly
- Behera Prafulla Kumar
- Behnamian Hadi
- Behnke Olaf
- Behrens Ulf
- Bein Samuel
- Beirão Da Cruz E Silva Cristóvão
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Beliy Nikita
- Belknap Donald
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Beluffi Camille
- Belyaev Alexander
- Belyaev Andrey
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benelli Gabriele
- Beni Noemi
- Benussi Luigi
- Benvenuti Alberto
- Beranek Sarah
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- Bernet Colin
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- Berryhill Jeffrey
- Bertl Willi
- Besancon Marc
- Betchart Burton
- Betts Russell Richard
- Bhandari Rohan
- Bhardwaj Ashutosh
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Rajarshi
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bhawandeep Bhawandeep
- Bhopatkar Vallary
- Bhowmik Sandeep
- Bi Ran
- Bialkowska Helena
- Bian Jian-Guo
- Bianchini Lorenzo
- Bianco Stefano
- Bierwagen Katharina
- Biino Cristina
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- Bornheim Adolf
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- Borzou Ahmad
- Bose Tulika
- Botta Cristina
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- Bourilkov Dimitri
- Bouvier Elvire
- Bowen James
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- Braghieri Alessandro
- Braibant-Giacomelli Sylvie
- Brandstetter Johannes
- Brandt Stephanie
- Branson James G
- Breedon Richard
- Breto Guillermo
- Brew Christopher
- Brianza Luca
- Brigliadori Luca
- Brigljevic Vuko
- Brinkerhoff Andrew
- Brinson Jessica
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- Brochero Cifuentes Javier Andres
- Brochet Sébastien
- Brodski Michael
- Brom Jean-Marie
- Brondolin Erica
- Brooke James John
- Brown Robert M
- Brun Hugues
- Bruner Christopher
- Bruno Giacomo
- Buchmuller Oliver
- Bucinskaite Inga
- Bundock Aaron
- Bunkowski Karol
- Bunn Julian
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- Burkett Kevin
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- Butler Philip H
- Buttignol Michael
- Butz Erik
- Bylinkin Alexander
- Bylsma Ben
- Byszuk Adrian
- Bäni Lukas
- Cabrera Andrés
- Cabrillo Iban Jose
- Cadamuro Luca
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- Calderon De La Barca Sanchez Manuel
- Calderon Alicia
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- Call Kenneth
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- Calpas Betty
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- Carpinteyro Severiano
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- Castle James
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- Cepeda Maria
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- Chabert Eric Christian
- Chadeeva Marina
- Chamizo Llatas Maria
- Chang Paoti
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- Chang Yu-Wei
- Chanon Nicolas
- Chao Yuan
- Chaparro Sierra Luisa Fernanda
- Chapon Emilien
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- Charlot Claude
- Chatterjee Kalyanmoy
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- Chaves Jorge
- Chawla Ridhi
- Chen Geng
- Chen Guo-Ming
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- Chenarani Shirin
- Cheng Tongguang
- Cherepanov Vladimir
- Chertok Maxwell
- Cheung Harry
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- Chierici Roberto
- Chinellato Jose
- Chiorboli Massimiliano
- Chistov Ruslan
- Chlebana Frank
- Cho Sungwoong
- Choi Minkyoo
- Choi Suyong
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C
- Choudhury Somnath
- Chtchipounov Leonid
- Chu Jennifer
- Chudasama Ruchi
- Chwalek Thorsten
- Ciangottini Diego
- Cieri Davide
- Cihangir Selcuk
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- Ciocci Maria Agnese
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- Cirkovic Predrag
- Citron Matthew
- Cittolin Sergio
- Ciulli Vitaliano
- Civinini Carlo
- Claes Daniel R
- Clare Robert
- Clarida Warren
- Clarke Christopher
- Clement Emyr
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- Cockerill David JA
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- Cooperstein Stephane
- Cornelis Tom
- Corpe Louie
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- Costa Marco
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- Coubez Xavier
- Couderc Fabrice
- Coughlan John A
- Courbon Benoit
- Cousins Robert
- Covarelli Roberto
- Cowden Christopher
- Cox Bradley
- Cox Peter Timothy
- Creanza Donato
- Cremonesi Matteo
- Cristella Leonardo
- Cuevas Javier
- Cuffiani Marco
- Cumalat John Perry
- Curras Esteban
- Curry David
- Cussans David
- Custódio Analu
- Cutts David
- Czellar Sandor
- D'Alessandro Raffaello
- D'Alfonso Mariarosaria
- D'Enterria David
- D'Hondt Jorgen
- D'imperio Giulia
- Da Silveira Gustavo Gil
- Dabrowski Anne
- Daci Nadir
- Dalchenko Mykhailo
- Dall'Osso Martino
- Dallavalle Gaetano-Marco
- Damarseckin Serdal
- Damgov Jordan
- Danilov Mikhail
- Daponte Vincenzo
- Das Souvik
- Daskalakis Georgios
- Dasu Sridhara
- Dauncey Paul
- David Tinoco Mendes Andre
- Davies Gavin
- Davignon Olivier
- de Barbaro Pawel
- De Boer Wim
- De Bruyn Isabelle
- De Castro Manzano Pablo
- De Cosa Annapaola
- De Filippis Nicola
- De Gruttola Michele
- De Guio Federico
- De Jesus Damiao Dilson
- De La Cruz Begona
- De La Cruz-Burelo Eduard
- De Lentdecker Gilles
- De Mattia Marco
- De Moraes Gregores Eduardo
- De Nardo Guglielmo
- De Oliveira Martins Carley
- De Palma Mauro
- De Remigis Paolo
- De Roeck Albert
- de Trocóniz Jorge F
- De Visscher Simon
- De Wit Adinda
- De Wolf Eddi A
- Degano Alessandro
- Deiters Konrad
- Dejardin Marc
- Del Re Daniele
- Delaere Christophe
- Delannoy Andrés G
- Delannoy Hugo
- Delcourt Martin
- Delgado Peris Antonio
- Delgado Andrea
- Dell'Orso Roberto
- Della Negra Michel
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- Demina Regina
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- Denegri Daniel
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- Deroover Kevin
- Dev Nabarun
- Devetak Damir
- Dewanjee Ram Krishna
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- Di Francesco Agostino
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- Di Marco Emanuele
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- Di Mattia Alessandro
- Diamond Brendan
- Diemoz Marcella
- Dierlamm Alexander
- Dietz Charles
- Dietz-Laursonn Erik
- Diez Pardos Carmen
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- Zaganidis Nicolas
- Zagoździńska Agnieszka
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zenoni Florian
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zeyrek Mehmet
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhao Jingzhou
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
- Zientek Margaret
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- Sunan Kalijaga State Islamic University
- Publication date
- 01/01/2012
- Field of study
Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
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- Ahmed Shahana
- Aimable Matthew
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- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
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- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
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- Amemiya Chris
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- Amin Amita G.
- Anderson Mechele
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- Antonarakis Stylianos E.
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- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
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- Gebreyesus Binyam
- Gelein Cynthia
- Gelpke Maartin
- Gench Stephanie L.
- Geng Jianing
- Georgescu Anca
- Geotina Amy
- Ghori Jilur
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- Gibbs Ben
- Gibbs Richard A.
- Gibson Diane
- Gibson Elizabeth
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- Gong Guanghui
- Gong Jinying
- Gonzales Eidelyn
- Gonzalez Guillermo B.
- Gooderham April
- Goodstadt Leo
- Goodstein David
- Goodwin Lynne A.
- Gordon Catherine
- Gordon Laurie A.
- Gordon Seth
- Gorton Matthew
- Gorvad Ann
- Gould Christine
- Goyea Ernest
- Goyette Audra
- Grady Deborah I.
- Grady Michelle L.
- Grafham Darren
- Graham Joe
- Grandbois Edward
- Grant Jennifer
- Grant Michael
- Grant Susan
- Graves Tina A.
- Gray Bruce
- Gray Emma
- Gray Lain
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- Gribble Susan
- Griffith Jeffrey K.
- Griffiths Coline
- Griffiths Ed
- Griffiths Mark
- Griffiths-Jones Sam
- Grigoriev Igor
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- Grocock Russell
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- Gu Jingli
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- Gu Wenyi
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- Guel Metzalli
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- Guevara Whitney V.
- Gui Qi
- Gunaratne Preethi
- Gunning Kate
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- Hammon Nancy
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- Hamza Khalid
- Han Guiqing
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- Hanak Vincent A.
- Hancock Julie
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- Harding Adam
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- Heyen Joshua
- Higgs Douglas
- Hildebrand Carl E.
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- Hillyard Guy
- Hines Sandra
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- Hinrichs Angela S.
- Hitchens Matthew Edward
- Ho Issac
- Ho Sara-Jane
- Hodgson Anne V.
- Hodgson David
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- Hoffs Michael
- Hogues Marilyn E.
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- Idlebird Devincent G.
- Iliev Ilian
- Imbro Paula
- Imo Kelvin C.
- Inacio Nicole
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- Ince Michael
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- Ishibashi Akiko
- Ishikawa Sabine K.
- Ishizaki Hinako
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- Jackson Terri
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- Jaeger Sara
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- Jaklevic Michael
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- Jia Jia
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- Khan Umer F.
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- Kosiura Anna
- Kou Zhaohui
- Kovar Christie L.
- Krawczyk Marie-Claude
- Kremitzki Colin
- Kremmidiotis Gabriel
- Krogh Anders
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- Kruchowski Scott S.
- Kube Michael
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- Lorensuhewa Lorna M.
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- Lowenstein Michael G.
- Lowry Stephen
- Lozado Ryan J.
- Lu Lingfeng
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- Lucier Raymond L.
- Ludeman Thom
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- MacLean Christine
- Madabhushi Ramki
- Madu Renita C.
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- Mareth David
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- Marra Marco
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- McMurray Kimberly
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- Meidi Patrick
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- Mercer Simon
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- Mesirov Jill P.
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- Mungall Andy
- Munidasa Mala
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- Murayama Yuji
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- Nair Seema R.
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- Nakagawa Masayo
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- Nusbaum Chad
- Nwaokelemeh Ogechi O.
- Nwokenkwo Stanley
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- O\u27Donovan Daniel
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- O\u27Loughlin Jennifer
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- Perez Agapito
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- Prathalingham Radhika
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- Thomas Daryl J.
- Thomas Karen
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- Thompson Linda S.
- Thorne Rachel Diane
- Thorpe Andrea
- Thorpe Karen
- Thoulutsang Yama
- Threadgold Glen
- Thurston Scott
- Tian Chaoguang
- Tian Chaoguang
- Tian Wei
- Tian Yan
- Tian Yong
- Tian Yuqing
- Tice Hope
- Tighe Damon
- Tin-Wollam Aye M.
- Tinsley Emma
- Tochigi Miwako
- Togashi Naoko
- Tomizawa Iori
- Tomlinson Chad
- Tong Jingli
- Topham Kerri
- Torcaso Bill
- Torney David C.
- Totoki Yasushi
- Towey Sarah
- Toyoda Atsushi
- Tracey Alan
- Tran Ly Thanh
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- Trani Lee
- Trankiem Margie
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- Travers Johnathan
- Trejos Zulma Y.
- Treuhaft Marianne
- Trevino Brenda Kaye
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- Trong Stephan
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- Tu Yuefeng
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- Xi Yan
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- Xu Jing
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- Xu Wei
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- Xu Yuning
- Xu Zhihong
- Xu Zuyuan
- Xuan Yali
- Xuan Zhenyu
- Xue Rui
- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
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- Yang Huanming
- Yang Huanming
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- Yang Shudong
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- Yao Zhijian
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- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
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