410 research outputs found

    Microwave-stimulated Raman adiabatic passage in a Bose-Einstein condensate on an atom chip

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    We report the achievement of stimulated Raman adiabatic passage (STIRAP) in the microwave frequency range between internal states of a Bose-Einstein condensate (BEC) magnetically trapped in the vicinity of an atom chip. The STIRAP protocol used in this experiment is robust to external perturbations as it is an adiabatic transfer, and power-efficient as it involves only resonant (or quasi-resonant) processes. Taking into account the effect of losses and collisions in a non-linear Bloch equations model, we show that the maximum transfer efficiency is obtained for non-zero values of the one- and two-photon detunings, which is confirmed quantitatively by our experimental measurements

    Women\u27s freedom of movement and participation in psychosocial support groups: Qualitative study in northern India

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    © 2019 The Author(s). Background: Depression, the world\u27s leading cause of disability, disproportionately affects women. Women in India, one of the most gender unequal countries worldwide, face systemic gender disadvantage that significantly increases the risk of common mental disorders. This study\u27s objective was to examine the factors influencing women\u27s participation in psychosocial support groups, within an approach where community members work together to collectively strengthen their community\u27s mental health. Methods: This community-based qualitative study was conducted from May to July 2016, across three peri-urban sites in Dehradun district, Uttarakhand, Northern India. Set within an NGO-run mental health project, data were collected through focus group discussions with individuals involved in psychosocial support groups including women with psychosocial disabilities as well as caregivers (N = 10, representing 59 women), and key informant interviews (N = 8) with community members and mental health professionals. Data were analyzed using a thematic analysis approach. Results: The principal barrier to participating in psychosocial support groups was restrictions on women\u27s freedom of movement. Women in the community are not normally permitted to leave home, unless going to market or work, making it difficult for women to leave their home to participate in the groups. The restrictions emanated from the overall community\u27s attitude toward gender relations, the women\u27s own internalized gender expectations, and most significantly, the decision-making power of husbands and mothers-in-law. Other factors including employment and education shaped women\u27s ability to participate in psychosocial support groups; however, the role of these additional factors must be understood in connection to a gender order limiting women\u27s freedom of movement. Conclusions: Mental health access and gender inequality are inseparable in the context of Northern India, and women\u27s mental health cannot be addressed without first addressing underlying gender relations. Community-based mental health programs are an effective tool and can be used to strengthen communities collectively; however, attention towards the gender constraints that restrict women\u27s freedom of movement and their ability to access care is required. To our knowledge, this is the first study to clearly document and analyze the connection between access to community mental health services in South Asia and women\u27s freedom of movement

    Cone beam computed tomography study of apical root resorption induced by Herbst appliance

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    Objective This study evaluated the frequency of root resorption during the orthodontic treatment with Herbst appliance by Cone Beam Computed Tomography (CBCT).Material and Methods The sample comprised 23 patients (11 men, 12 women; mean ages 15.76±1.75 years) with Class II division 1 malocclusion, treated with Herbst appliance. CBCT was obtained before treatment (T0) and after Herbst treatment (T1). All the dental roots, except third molars, were evaluated, and apical root resorption was determined using the axial guided navigation method. Paired t-tests and Wilcoxon T Test were used to compare the dependent samples in parametric and nonparametric cases, respectively. Chi-Square Test with Yates’ correction was used to evaluate the relationship between apical root resorption and gender. Results were considered at a significance level of 5%.Results Apical resorption was detected by CBCT in 57.96% of 980 roots that underwent Herbst appliance treatment. All patients had minimal resorption and there was no statistical significance between the genders.Conclusion CBCT three-dimensional evaluation showed association between Herbst appliance and minimal apical root resorption, mostly in the anchoring teeth, without clinical significance

    Source tracing of detrital serpentinite in the Oligocene molasse deposits from the western Alps (Barrême basin): implications for relief formation in the internal zone.

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    International audienceWe present the first contribution of tracing the source area of ophiolitic detritus in the Alpine molasses by Raman spectroscopy. The lower Oligocene molasse deposits preserved in the Barrême basin, in the SW foreland of the western Alpine arc, are known for the sudden arrival of the first "exotic" detritus coming from the internal Alpine zones. Among them, the pebbles of serpentinized peridotites have so far not been studied. We show that they only consist of antigorite serpentinite, implying that they originate from erosion of HT-blueschists. In contrast, the upper Oligocene/lower Miocene molasse, shows mixed clasts of serpentine including antigorite and lizardite without any evidence of chrysotile. This suggests that they were derived from a less metamorphosed unit such as the LT-blueschist unit. Taking into account the sediment transport direction in the basin and the varied metamorphic characteristics of the other ocean-derived detritus, we constrain the lithological nature of the source zones and the location of the relief zones, identified as the internal Alps, SE of the Pelvoux external crystalline massif. Available structural data and in situ thermochronological data allow reconstructing the Oligocene to early Miocene collisional geometry of the Paleogene subduction wedge. This phase corresponds to two major phases of uplift evolving from a single relief zone located above the Ivrea body during the early Oligocene and persisting up to the early Miocene; then during the late Oligocene/early Miocene a second relief zone developed above the Briançonnais zone. At that time, the internal western Alps acquired its double vergency

    Reverse production effect: Children recognize novel words better when they are heard rather than produced

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    This is the peer reviewed version of the following article: Tania S. Zamuner, Stephanie Strahm, Elizabeth Morin-Lessard, and Michael P. A. Page, 'Reverse production effect: children recognize novel words better when they are heard rather than produced', Developmental Science, which has been published in final form at DOI 10.1111/desc.12636. Under embargo until 15 November 2018. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.This research investigates the effect of production on 4.5- to 6-year-old children’s recognition of newly learned words. In Experiment 1, children were taught four novel words in a produced or heard training condition during a brief training phase. In Experiment 2, children were taught eight novel words, and this time training condition was in a blocked design. Immediately after training, children were tested on their recognition of the trained novel words using a preferential looking paradigm. In both experiments, children recognized novel words that were produced and heard during training, but demonstrated better recognition for items that were heard. These findings are opposite to previous results reported in the literature with adults and children. Our results show that benefits of speech production for word learning are dependent on factors such as task complexity and the developmental stage of the learner.Peer reviewedFinal Accepted Versio

    Progress and challenges in incorporating climate change information into transportation research and design

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    The vulnerability of our nation\u27s transportation infrastructure to climate change and extreme weather is now well documented and the transportation community has identified numerous strategies to potentially mitigate these vulnerabilities. The challenges to the infrastructure sector presented by climate change can only be met through collaboration between the climate science community, who evaluate what the future will likely look like, and the engineering community, who implement our societal response. To facilitate this process, the authors asked: what progress has been made and what needs to be done now in order to allow for the graceful convergence of these two disciplines? In late 2012, the Infrastructure and Climate Network (ICNet), a National Science Foundation-supported research collaboration network, was established to answer that question. This article presents examples of how the ICNet experience has shown the way toward a new generation of innovation and cross-disciplinary research, challenges that can be address by such collaboration, and specific guidance for partnerships and methods to effectively address complex questions requiring a cogeneration of knowledge

    Cone beam computed tomography study of apical root resorption induced by Herbst appliance

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    Objective This study evaluated the frequency of root resorption during the orthodontic treatment with Herbst appliance by Cone Beam Computed Tomography (CBCT).Material and Methods The sample comprised 23 patients (11 men, 12 women; mean ages 15.76±1.75 years) with Class II division 1 malocclusion, treated with Herbst appliance. CBCT was obtained before treatment (T0) and after Herbst treatment (T1). All the dental roots, except third molars, were evaluated, and apical root resorption was determined using the axial guided navigation method. Paired t-tests and Wilcoxon T Test were used to compare the dependent samples in parametric and nonparametric cases, respectively. Chi-Square Test with Yates’ correction was used to evaluate the relationship between apical root resorption and gender. Results were considered at a significance level of 5%.Results Apical resorption was detected by CBCT in 57.96% of 980 roots that underwent Herbst appliance treatment. All patients had minimal resorption and there was no statistical significance between the genders.Conclusion CBCT three-dimensional evaluation showed association between Herbst appliance and minimal apical root resorption, mostly in the anchoring teeth, without clinical significance

    Mammalian Small Nucleolar RNAs Are Mobile Genetic Elements

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    Small nucleolar RNAs (snoRNAs) of the H/ACA box and C/D box categories guide the pseudouridylation and the 2′-O-ribose methylation of ribosomal RNAs by forming short duplexes with their target. Similarly, small Cajal body–specific RNAs (scaRNAs) guide modifications of spliceosomal RNAs. The vast majority of vertebrate sno/scaRNAs are located in introns of genes transcribed by RNA polymerase II and processed by exonucleolytic trimming after splicing. A bioinformatic search for orthologues of human sno/scaRNAs in sequenced mammalian genomes reveals the presence of species- or lineage-specific sno/scaRNA retroposons (sno/scaRTs) characterized by an A-rich tail and an ∼14-bp target site duplication that corresponds to their insertion site, as determined by interspecific genomic alignments. Three classes of snoRTs are defined based on the extent of intron and exon sequences from the snoRNA parental host gene they contain. SnoRTs frequently insert in gene introns in the sense orientation at genomic hot spots shared with other genetic mobile elements. Previously characterized human snoRNAs are encoded in retroposons whose parental copies can be identified by phylogenic analysis, showing that snoRTs can be faithfully processed. These results identify snoRNAs as a new family of mobile genetic elements. The insertion of new snoRNA copies might constitute a safeguard mechanism by which the biological activity of snoRNAs is maintained in spite of the risk of mutations in the parental copy. I furthermore propose that retroposition followed by genetic drift is a mechanism that increased snoRNA diversity during vertebrate evolution to eventually acquire new RNA-modification functions
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