Microescultura de la superficie de las cipselas de Baccharis sect. Caulopterae (Asteraceae) de Brasil.

The aim of this study was to characterize the microsculpture of the cypselae surface of the Brazilian species of Baccharis L. sect. Caulopterae DC. (Asteraceae), and to compare this data it with the taxonomy of the group. Scanning electron microscopy was used to examine the cypsela surface of 25 taxa of Baccharis sect. Caulopterae from Brazil. According to the micromorphology of the cypsela surface, the species can be classified into five distinct groups. The cypselae of the species of the Baccharis trimera species complex (B. crispa, B. cylindrica, B. jocheniana, B. myriocephala, and B. trimera) share the same micromorphological features.Para examinar la superficie de cipselas de 25 táxones de Baccharis L. sect. Caulopterae DC. de Brasil se ha utilizado la microscopía electrónica de barrido. El objetivo del estudio fue caracterizar la microescultura de la superficie de cipselas de la sección y colaborar con la delimitación taxonómica a nivel específico. Las especies fueron clasificadas en cinco grupos distintos según la micromorfología y asignados a la terminología existente. El complejo Baccharis trimera (B. crispa, B. cylindrica, B. jocheniana, B. myriocephala y B. trimera) mostró afinidades micromorfológicas de las cipselas

Estudo florístico e fitossociológico de uma área às margens da lagoa do Armazém, Osório, Rio Grande do Sul, Brasil

O trabalho foi desenvolvido no município de Osório, em uma área com ca. de 10 hectares, constituída predominantemente por vegetação campestre e em menor proporção por vegetação florestal. O objetivo foi de conhecer a flora local, com ênfase para as espécies raras, endêmicas, ameaçadas de extinção e exóticas. O levantamento florístico foi realizado através do método do Caminhamento. Para o conhecimento das espécies mais freqüentes na vegetação de campo foi realizado levantamento fitossociológico utilizando-se o método de superfície, com 18 parcelas de 1m². Para a estimativa de cobertura foi utilizada a escala modificada de Braun-Blanquet. Foi registrada a ocorrência de 183 espécies distribuídas em 54 famílias. Dentre elas uma espécie endêmica dos campos litorâneos, duas em perigo de extinção, seis vulneráveis e duas imunes ao corte. Além disso, foram constatadas duas tipologias campestres, uma em área úmida com composição florística essencialmente nativa e outra de campo seco com vegetação alterada dominada principalmente por espécies exóticas e ruderais

Notas nomenclaturais em Baccharis L. sect. Caulopterae DC. (Asteraceae)

The work presents nomenclatural notes about some Brazilian species of Baccharis sect. Caulopterae DC. The study was based on literature and herbaria revision, including study of types, and field observations. As results, the lectotypification of Baccharis organensis Baker and eight heterotypic synonyms are proposed. Comments justifying the propositions are provided.O trabalho trata de notas nomenclaturais sobre espécies de Baccharis sect. Caulopterae DC. ocorrentes no Brasil. O estudo foi baseado em revisão de literatura, exame de coleções em herbários, incluindo tipos, e observações a campo. Como resultados, a lectotipificação de Baccharis organensis Baker é proposta e 14 sinônimos homotípicos e heterotípicos são aceitos, dos quais 11 são inéditos. Comentários justificando as proposições apresentadas são fornecidos

Isolation and characterization of twelve polymorphic microsatellite loci for Hypochaeris catharinensis (Asteraceae) and cross-amplification in related species

Fil: Chaves, Camila Lucas. Universidade Estadual de Londrina; BrasilFil: Ruas, Claudete Fátima. Universidade Estadual de Londrina; BrasilFil: Ruas, Paulo Maurício. Universidade Estadual de Londrina; BrasilFil: Schneider, Angelo Alberto. Centro Anacreonte Ávila de Araújo. Fundação Estadual de Pesquisa Agropecuária; BrasilFil: Rocha, Kátia Real. Universidade Estadual de Londrina; BrasilFil: Urtubey, Estrella. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Botánica Darwinion. Academia Nacional de Ciencias Exactas, Físicas y Naturales. Instituto de Botánica Darwinion; ArgentinaFil: Ruas, Eduardo Augusto. Universidade Estadual de Londrina; Brasi

A família Asteraceae no Parque Estadual de Itapuã, Viamão, Rio Grande do Sul, Brasil

The Parque Estadual de Itapuã, situated in the municipal district of Viamão, a important preservation area of Rio Grande do Sul state by sheltering remainders of original vegetation. The Asteraceae family presented a large number of species and wide distribution, principally in grassland habitat. The aim of this work is to register the Asteraceae species which occurrence in the study area, thus contributing for the better knowledge of this family. For this, a bibliographic and regional herbarium revision was realized involving others studies previously accomplished in Itapuã Park. Habit, habitats and phenology data ware registered for every species. We encountered 163 species, allotted in 13 tribes. The more numerous tribes were Astereae (36 species) and Eupatorieae (32 species). The collected examples flourish and fructify mostly in spring (51%) and autumn (46%). The large number of the species found, begin six menaced of extinction, denoted the importance this Conservation Unit to Rio Grande do Sul state.O Parque Estadual de Itapuã, localizado no município de Viamão, Rio Grande do Sul, é uma importante área de preservação do Estado, uma vez que abriga remanescentes da vegetação original da região. A família Asteraceae apresenta um grande número de espécies e uma ampla distribuição, sendo que no sul do Brasil ocorre em maior número nas formações campestres. O objetivo deste trabalho é inventariar as espécies de Asteraceae ocorrentes na área de estudo, contribuindo para o conhecimento da família. Para tanto, realizou-se uma revisão de trabalhos efetuados no Parque, além dos exemplares anteriormente coletados no local e depositados nos herbários da região. Foram registrados dados como hábito, hábitats, floração e frutificação para cada espécie coletada. Encontraram-se 163 espécies, distribuídas em 13 tribos. A tribo com o maior número de representantes é Astereae (36 espécies), seguida por Eupatorieae (32 espécies). Os exemplares coletados florescem e frutificam principalmente na primavera (51%) e no outono (46%). A ocorrência de um grande número de espécies da família, sendo que seis ameaçadas de extinção, indicam a importância desta Unidade de Conservação para o Estado

Impact of safety-related dose reductions or discontinuations on sustained virologic response in HCV-infected patients: Results from the GUARD-C Cohort

BACKGROUND: Despite the introduction of direct-acting antiviral agents for chronic hepatitis C virus (HCV) infection, peginterferon alfa/ribavirin remains relevant in many resource-constrained settings. The non-randomized GUARD-C cohort investigated baseline predictors of safety-related dose reductions or discontinuations (sr-RD) and their impact on sustained virologic response (SVR) in patients receiving peginterferon alfa/ribavirin in routine practice. METHODS: A total of 3181 HCV-mono-infected treatment-naive patients were assigned to 24 or 48 weeks of peginterferon alfa/ribavirin by their physician. Patients were categorized by time-to-first sr-RD (Week 4/12). Detailed analyses of the impact of sr-RD on SVR24 (HCV RNA <50 IU/mL) were conducted in 951 Caucasian, noncirrhotic genotype (G)1 patients assigned to peginterferon alfa-2a/ribavirin for 48 weeks. The probability of SVR24 was identified by a baseline scoring system (range: 0-9 points) on which scores of 5 to 9 and <5 represent high and low probability of SVR24, respectively. RESULTS: SVR24 rates were 46.1% (754/1634), 77.1% (279/362), 68.0% (514/756), and 51.3% (203/396), respectively, in G1, 2, 3, and 4 patients. Overall, 16.9% and 21.8% patients experienced 651 sr-RD for peginterferon alfa and ribavirin, respectively. Among Caucasian noncirrhotic G1 patients: female sex, lower body mass index, pre-existing cardiovascular/pulmonary disease, and low hematological indices were prognostic factors of sr-RD; SVR24 was lower in patients with 651 vs. no sr-RD by Week 4 (37.9% vs. 54.4%; P = 0.0046) and Week 12 (41.7% vs. 55.3%; P = 0.0016); sr-RD by Week 4/12 significantly reduced SVR24 in patients with scores <5 but not 655. CONCLUSIONS: In conclusion, sr-RD to peginterferon alfa-2a/ribavirin significantly impacts on SVR24 rates in treatment-naive G1 noncirrhotic Caucasian patients. Baseline characteristics can help select patients with a high probability of SVR24 and a low probability of sr-RD with peginterferon alfa-2a/ribavirin

Astrophysics with the Laser Interferometer Space Antenna

Laser Interferometer Space Antenna (LISA) will be a transformative experiment for gravitational wave astronomy as it will offer unique opportunities to address many key astrophysical questions in a completely novel way. The synergy with ground-based and other space-based instruments in the electromagnetic domain, by enabling multi-messenger observations, will add further to the discovery potential of LISA. The next decade is crucial to prepare the astrophysical community for LISA's first observations. This review outlines the extensive landscape of astrophysical theory, numerical simulations, and astronomical observations that are instrumental for modeling and interpreting the upcoming LISA datastream. To this aim, the current knowledge in three main source classes for LISA is reviewed: ultra-compact stellar-mass binaries, massive black hole binaries, and extreme or intermediate mass ratio inspirals. The relevant astrophysical processes and the established modeling techniques are summarized. Likewise, open issues and gaps in our understanding of these sources are highlighted, along with an indication of how LISA could help make progress in the different areas. New research avenues that LISA itself, or its joint exploitation with studies in the electromagnetic domain, will enable, are also illustrated. Improvements in modeling and analysis approaches, such as the combination of numerical simulations and modern data science techniques, are discussed. This review is intended to be a starting point for using LISA as a new discovery tool for understanding our Universe

Associations between depressive symptoms and disease progression in older patients with chronic kidney disease: results of the EQUAL study

Background Depressive symptoms are associated with adverse clinical outcomes in patients with end-stage kidney disease; however, few small studies have examined this association in patients with earlier phases of chronic kidney disease (CKD). We studied associations between baseline depressive symptoms and clinical outcomes in older patients with advanced CKD and examined whether these associations differed depending on sex. Methods CKD patients (&gt;= 65 years; estimated glomerular filtration rate &lt;= 20 mL/min/1.73 m(2)) were included from a European multicentre prospective cohort between 2012 and 2019. Depressive symptoms were measured by the five-item Mental Health Inventory (cut-off &lt;= 70; 0-100 scale). Cox proportional hazard analysis was used to study associations between depressive symptoms and time to dialysis initiation, all-cause mortality and these outcomes combined. A joint model was used to study the association between depressive symptoms and kidney function over time. Analyses were adjusted for potential baseline confounders. Results Overall kidney function decline in 1326 patients was -0.12 mL/min/1.73 m(2)/month. A total of 515 patients showed depressive symptoms. No significant association was found between depressive symptoms and kidney function over time (P = 0.08). Unlike women, men with depressive symptoms had an increased mortality rate compared with those without symptoms [adjusted hazard ratio 1.41 (95% confidence interval 1.03-1.93)]. Depressive symptoms were not significantly associated with a higher hazard of dialysis initiation, or with the combined outcome (i.e. dialysis initiation and all-cause mortality). Conclusions There was no significant association between depressive symptoms at baseline and decline in kidney function over time in older patients with advanced CKD. Depressive symptoms at baseline were associated with a higher mortality rate in men

Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

The production of tt‾ , W+bb‾ and W+cc‾ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓν , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of $t\overline{t}$, $W+b\overline{b}$ and $W+c\overline{c}$ is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 $\pm$ 0.02 \mbox{fb}^{-1}. The $W$ bosons are reconstructed in the decays $W\rightarrow\ell\nu$, where $\ell$ denotes muon or electron, while the $b$ and $c$ quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions