36 research outputs found

    Marina Abramović : from the artist to the present

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    Marina Abramovic: From the Artist to the Present mostra una investigació entom a l'artista serbia entre 2010 i 2014. El punt d'inici és The Artist is Present, la seva retrospectiva i obra homónima realitzada al Museum of Modern Art de Nova York, el punt de màxima consolidació d'una artista de performance a la historia de l'art i el reconeixement del públic i la crítica. El treball intenta mostrar la seva trajectoria posterior a l'obra per cobrir el buit bibliografic existent.Marina Abramovic: From the Artist to the Present muestra una investigación realizada entorno a la artista serbia entre 2010 y 2014. El punto de inicio es The Artist is Present, su retrospectiva y obra homónima en el Museum of Modern Art de Nueva York; el punto de máxima consolidación de una artista de performance en la historia del arte y el reconocimiento de público y crítica. El trabajo intenta mostrar la trayectoria posterior a esta obra para cubrir el vacío bibliográfico existente.Marina Abramovic: From the Artist to the Present is a research focused on the serbian artist between 2010 and 2014. The starting point is The Artist is Present, a retrospective in the Museum ofModem Art in New York and the main artwork of the exhibition. It was moment when a performance artist became most stablished by a big institution and art criticism. The main theme of the research is to create a documental resource to group all the artworks from 2010 in a single study

    Identification of regulatory variants associated with genetic susceptibility to meningococcal disease.

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    Non-coding genetic variants play an important role in driving susceptibility to complex diseases but their characterization remains challenging. Here, we employed a novel approach to interrogate the genetic risk of such polymorphisms in a more systematic way by targeting specific regulatory regions relevant for the phenotype studied. We applied this method to meningococcal disease susceptibility, using the DNA binding pattern of RELA - a NF-kB subunit, master regulator of the response to infection - under bacterial stimuli in nasopharyngeal epithelial cells. We designed a custom panel to cover these RELA binding sites and used it for targeted sequencing in cases and controls. Variant calling and association analysis were performed followed by validation of candidate polymorphisms by genotyping in three independent cohorts. We identified two new polymorphisms, rs4823231 and rs11913168, showing signs of association with meningococcal disease susceptibility. In addition, using our genomic data as well as publicly available resources, we found evidences for these SNPs to have potential regulatory effects on ATXN10 and LIF genes respectively. The variants and related candidate genes are relevant for infectious diseases and may have important contribution for meningococcal disease pathology. Finally, we described a novel genetic association approach that could be applied to other phenotypes

    MAGIC and H.E.S.S. detect VHE gamma rays from the blazar OT081 for the first time: a deep multiwavelength study

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    https://pos.sissa.it/395/815/pdfPublished versio

    Functional organization of human subgenual cortical areas: Relationship between architectonical segregation and connectional heterogeneity

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    Human subgenual anterior cingulate cortex (sACC) is involved in affective experiences and fear processing. Functional neuroimaging studies view it as a homogeneous cortical entity. However, sACC comprises several distinct cyto- and receptorarchitectonical areas: 25, s24, s32, and the ventral portion of area 33. Thus, we hypothesized that the areas may also be connectionally and functionally distinct. We performed structural post mortem and functional in vivo analyses. We computed probabilistic maps of each area based on cytoarchitectonical analysis of ten post mortem brains. Maps, publicly available via the JuBrain atlas and the Anatomy Toolbox, were used to define seed regions of task-dependent functional connectivity profiles and quantitative functional decoding. sACC areas presented distinct co-activation patterns within widespread networks encompassing cortical and subcortical regions. They shared common functional domains related to emotion, perception and cognition. A more specific analysis of these domains revealed an association of s24 with sadness, and of s32 with fear processing. Both areas were activated during taste evaluation, and co-activated with the amygdala, a key node of the affective network. s32 co-activated with areas of the executive control network, and was associated with tasks probing cognition in which stimuli did not have an emotional component. Area 33 was activated by painful stimuli, and co-activated with areas of the sensorimotor network. These results support the concept of a connectional and functional specificity of the cyto- and receptorarchitectonically defined areas within the sACC, which can no longer be seen as a structurally and functionally homogeneous brain region

    Probabilistic cytoarchitectonic map of Area hOc5 (LOC) (v2.4)

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    This dataset contains the distinct architectonic Area hOc5 (LOC) in the individual, single subject template of the MNI Colin 27 as well as the MNI ICBM 152 2009c nonlinear asymmetric reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to both reference spaces, where each voxel was assigned the probability to belong to Area hOc5 (LOC). The probability map of Area hOc5 (LOC) is provided in the NifTi format for each brain reference space and hemisphere. The Julich-Brain atlas relies on a modular, flexible and adaptive framework containing workflows to create the probabilistic brain maps for these structures. Note that methodological improvements and integration of new brain structures may lead to small deviations in earlier released datasets. Other available data versions of Area hOc5 (LOC): Malikovic et al. (2018) [Data set, v2.2] [DOI: 10.25493/BPG7-360](https://doi.org/10.25493%2FBPG7-360) The most probable delineation of Area hOc5 (LOC) derived from the calculation of a maximum probability map of all currently released Julich-Brain brain structures can be found here: Amunts et al. (2019) [Data set, v1.13] [DOI: 10.25493/Q3ZS-NV6](https://doi.org/10.25493%2FQ3ZS-NV6) Amunts et al. (2019) [Data set, v1.18] [DOI: 10.25493/8EGG-ZAR](https://doi.org/10.25493%2F8EGG-ZAR) Amunts et al. (2020) [Data set, v2.2] [DOI: 10.25493/TAKY-64D](https://doi.org/10.25493%2FTAKY-64D

    Probabilistic cytoarchitectonic map of Area Fo2 (OFC) (v3.4)

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    This dataset contains the distinct architectonic Area Fo2 (OFC) in the individual, single subject template of the MNI Colin 27 as well as the MNI ICBM 152 2009c nonlinear asymmetric reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to both reference spaces, where each voxel was assigned the probability to belong to Area Fo2 (OFC). The probability map of Area Fo2 (OFC) are provided in the NifTi format for each brain reference space and hemisphere. The Julich-Brain atlas relies on a modular, flexible and adaptive framework containing workflows to create the probabilistic brain maps for these structures. Note that methodological improvements and integration of new brain structures may lead to small deviations in earlier released datasets. Other available data versions of Area Fo2 (OFC): Henssen et al. (2018) [Data set, v3.2] [DOI: 110.25493/N14D-JQT](https://doi.org/10.25493%2FN14D-JQT) The most probable delineation of Area Fo2 (OFC) derived from the calculation of a maximum probability map of all currently released Julich-Brain brain structures can be found here: Amunts et al. (2019) [Data set, v1.13] [DOI: 10.25493/Q3ZS-NV6](https://doi.org/10.25493%2FQ3ZS-NV6) Amunts et al. (2019) [Data set, v1.18] [DOI: 10.25493/8EGG-ZAR](https://doi.org/10.25493%2F8EGG-ZAR) Amunts et al. (2020) [Data set, v2.2] [DOI: 10.25493/TAKY-64D](https://doi.org/10.25493%2FTAKY-64D
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