91 research outputs found
OLS data system/global survey of lightning
A global lightning climatology is being assembled from the nighttime imagery of the DMSP Optical Linescan Sensor (OLS). Lightning saturates the visible channel of the OLS at nighttime and can be identified as a horizontal streak on the order of 50-100 km in horizontal extent. Lightning streaks apparent in the film strips located at the National Snow and Ice Data Center (NSIDC) prior to 1991 are being digitized. An initial survey was completed for the F7 satellite observation period January 1986 - October 1987 and for the Q satellite for the period June-July 1973. Comparisons between the OLS lightning climatology with the Arkin GPI data set during the 1986-87 El Nino event shows similar regional variations in convective activity. The digital archive of global DMSP data began at the end of February. Software is being developed at both MSFC and NSIDC to extract, navigate, and view the OLS fine and smooth imagery
The Relationship Between Cognitive Functions and Sport-Specific Motor Skills in Elite Youth Soccer Players
The aim of the present study was to examine the relationship between basic cognitive functions and sport-specific motor skills in elite youth soccer players. A total of 15 elite youth soccer players aged 11–13 years performed a computer-based test battery measuring the attention window (AW), perceptual load (PL), working memory capacity (WMC), and multiple object tracking (MOT). Another set of tests was used to asses speed abilities and football-specific technical skills (sprint, change of direction, dribbling, ball control, shooting, and juggling). Spearman’s correlation tests showed that the diagonal AW was positively associated with dribbling skills (rs = 0.656) which indicates that a broader AW could be beneficial for highly demanding motor skills like dribbling. WMC was positively related to dribbling (rs = 0.562), ball control (rs = 0.669), and ball juggling (rs = 0.727). Additionally, the cumulated score of all cognitive tests was positively related to the cumulated motor test score (rs = 0.614) which supports the interplay of physical and psychological skills. Our findings highlight the need for more, and especially longitudinal, studies to enhance the knowledge of cognition-motor skill relationships for talent identification, talent development, and performance in soccer
Confining the Concept of Vascular Depression to Late-Onset Depression: A Meta-Analysis of MRI-Defined Hyperintensity Burden in Major Depressive Disorder and Bipolar Disorder
Background: The vascular depression hypothesis emphasizes the significance of vascular lesions in late-life depression. At present, no meta-analytic model has investigated whether a difference in hyperintensity burden compared to controls between late-life and late-onset depression is evident. By including a substantial number of studies, focusing on a meaningful outcome measure, and considering several moderating and control variables, the present meta-analysis investigates the severity of hyperintensity burden in major depressive disorder (MDD) and bipolar disorder (BD). A major focus of the present meta-analysis refers to the role of age at illness onset. It is analyzed whether late-onset rather than late-life depression characterizes vascular depression.Method: In total, 68 studies were included in the meta-analysis and a multilevel random effects model was calculated using Hedges' g as the effect size measure.Results: The severity of hyperintensity burden was significantly greater in the patient group compared to the control group. This effect was evident regarding the whole patient group (g = 0.229) as well as both depression subgroups, with a significantly greater effect in BD (g = 0.374) compared to MDD (g = 0.189). Hyperintensity burden was more pronounced in late-onset depression than in early-onset depression or late-life depression. A considerable heterogeneity between the included studies was observed, which is reflected by the large variability in effects sizes.Conclusion: In conclusion, the present meta-analysis underscores the association of hyperintensities with MDD and BD. Especially late-onset depression is associated with an increased hyperintensity burden, which is in line with the vascular depression hypothesis. The results suggest that it might be more feasible to confine the concept of vascular depression specifically to late-onset depression as opposed to late-life depression. Further research is needed to understand the causal mechanisms that might underlie the relation between hyperintensity burden and depression
Deliberate Soccer Practice Modulates Attentional Functioning in Children
We thank all the players, parents, coaches, and staff members
of Valencia C.F. and the students, parents, and teachers of the
Villar Palasí Primary Education School (Sagunto, Spain) for their
participation in this research project.The main purpose of this study was to explore the association between the
regular practice of open-skill sports (i.e., soccer) and executive control, along with
other attentional functions (i.e., alerting and orienting) during preadolescence. The
study was conducted on 131 participants (70 non-athletes and 61 soccer players).
To measure cognitive performance, participants performed the Attentional Network
Test—Interactions (ANT-I) task. Compared to non-athletes, soccer players showed
overall faster responses and better executive control (e.g., reduced interference from
distractors). Overall, our results provide new empirical evidence supporting the positive
association between regular sports practice and cognitive performance, and more
specifically executive functions. However, is important to note that the relationship
between regular sport practice and cognition is complex and multifactorial. Our findings
can be partly explained by the “cardiovascular fitness hypothesis” and the “cognitive
component skills approach,” suggesting that an externally paced sport environment
with high physical fitness and perceptual–cognitive demands may be an appropriate
setting to optimize the development of cognitive functioning during early adolescence.This research was supported by grants from San Vicente Mártir
Catholic University of Valencia (2019-158-003 to FH and 2018-
158-004 to CM) and the Spanish Ministry of Economy, Industry
and Competitiveness (PSI2017-84926-P) to JL and FH. The
funding bodies had no role in the study design, the data
collection and analysis, decision to publish, or preparation
of the manuscript
BCNU for recurrent glioblastoma multiforme: efficacy, toxicity and prognostic factors
<p>Abstract</p> <p>Background</p> <p>The prognosis for patients with recurrent glioblastoma is still poor with a median survival between 3 and 6 months. Reports about the application of carmustine (BCNU), one of the standard chemotherapeutic drugs in the treatment of newly diagnosed glioblastoma, in the recurrent situation are rare.</p> <p>Methods</p> <p>We performed a retrospective analysis of 35 patients with recurrent or progressive glioblastoma treated with 80 mg/m<sup>2 </sup>BCNU on days 1 on 3 intravenously at our department for efficacy, toxicity and prognostic factors. Progression free survival and overall survival were estimated by the Kaplan-Meier method. The influence of age, Karnofsky performance status (KPS), tumor burden, pretreatment with temozolomide (TMZ), type of surgery for initial diagnosis and number of previous relapses on outcome was analyzed in a proportional hazards regression model.</p> <p>Results</p> <p>The median age of the group was 53 years, median KPS was 70. Median progression free survival was 11 weeks (95% confidence interval [CI]: 8-15), median overall survival 22 weeks (95% CI: 18-27). The rate of adverse events, especially hematological toxicity, is relatively high, and in 3 patients treatment had to be terminated due to adverse events (one pulmonary embolism, one pulmonary fibrosis, and one severe bone marrow suppression). No influence of age, KPS, tumor burden, pre-treatment with TMZ and number of previous relapses on outcome could be demonstrated, while gross total resection prior to recurrence showed a borderline statistically significant negative impact on PFS and OS. These data compare well with historical survival figures. However prospective randomized studies are needed to evaluate BCNU efficacy against newer drugs like bevacizumab or the intensified temozolomide regime (one week on/one week off).</p> <p>Conclusion</p> <p>In summary, BCNU treatment appears to be a valuable therapeutic option for recurrent glioblastomas, where no other validated radio- and/or chemotherapy are available.</p
Effect of jenny milk addition on the inhibition of late blowing in semihard cheese
The occurrence of late blowing defects in cheese produces negative effects on the quality and commercial value of the product. In this work, we verified whether the addition of raw jenny milk to bulk cow milk reduced the late blowing defects in semihard cheeses. During cheesemaking, different aliquots of jenny milk were poured into 2 groups of 4 vats, each containing a fixed amount of cow milk. A group of cheeses was created by deliberately contaminating the 4 vats with approximately 3 log10 cfu/mL milk of Clostridium tyrobutyricum CLST01. The other 4 vats, which were
not contaminated, were used for a second group of cheeses. After 120 d of ripening, some physical, chemical, and microbiological parameters were evaluated on the obtained semihard cheeses. Differences in sensory properties among cheeses belonging to the uncontaminated group were evaluated by 80 regular consumers of cheese. Our results showed that the increasing addition
of jenny milk to cow milk led to a reduction of pH and total bacterial count in both cheese groups, as well as C. tyrobutyricum spores that either grew naturally or artificially inoculated. We observed a progressive reduction of the occurrence of late blowing defects in cheese as consequence of the increasing addition of jenny milk during cheese making. Moreover, the addition of jenny milk did not affect the acceptability of the product, as consumers found no difference among cheeses concerning sensorial aspects. In conclusion, the important antimicrobial activity of lysozyme contained in jenny milk has been confirmed in the current research. It is recommend for use as a possible and viable alternative to egg lysozyme for controlling late blowing defects in
cheese
Radiotherapeutic alternatives for previously irradiated recurrent gliomas
Re-irradiation for recurrent gliomas has been discussed controversially in the past. This was mainly due to only marginal palliation while being associated with a high risk for side effects using conventional radiotherapy
Iodine-125 brachytherapy for brain tumours - a review
Iodine-125 brachytherapy has been applied to brain tumours since 1979. Even though the physical and biological characteristics make these implants particularly attractive for minimal invasive treatment, the place for stereotactic brachytherapy is still poorly defined
Stereotactic iodine-125 brachytherapy for brain tumors: temporary versus permanent implantation
Diversity of the genus Frustulia in northern Europe
Genus Frustulia was chosen for this work due to the continuity of the previous research of our phycological group. Using molecular techniques, it was found that a number of morphologically defined species of diatoms is cryptic species complex, which may have limited dispersal. The aim of this study was to: 1) evaluate the diversity of the genus Frustulia in northern Europe by molecular methods and classify found species in the phylogenetic context of related species; 2) find out if it possible to identify the isolated species in natural samples by using morphological characters. There have been analyzed 234 strains by molecular methods. Isolated ones were in four clades. 86 % of the strains belonged to a generic complex F. crassinervia-saxonica. Two strains were identified as species F. gaertnerae and F. septentrionalis. The last line was not described yet so it was labeled as F. sp. This line is closely related to the species F. maoriana, which is considered to be endemic in New Zealand. Phylogeny of the genus was created based on a dataset of four molecular markers. Published morphometric data were then compared with 264 cells photos taken by scanning electron microscope. There was done surveillance comparison of the results of the analysis of quantitative and qualitative characters with..
- …