Truffaut’s L’Enfant sauvage (The Wild Child, 1970): Evoking Autism and the Nascent “Eugenic Atlantic”

This essay analyzes François Truffaut’s L’Enfant sauvage (The Wild Child, 1970) as an early representation of autism that metaphorizes the neurodiverse child as the colonial subject. The film takes place in 1798, only a decade after the French Revolution, and depicts the true events of the “wild boy of Aveyron,” a feral child found in the Southern French forest when he was twelve years old. Before the film’s production, Truffaut—who also plays the boy’s teacher, Dr. Jean-Marc Itard—collected articles and books on autism and viewed videos of autistic children to create his main character’s behavioral patterns. The film is thus an exceptionally early representation of autism in narrative film history. While several scholars have analyzed the film with this knowledge—and often through an autobiographical lens that uncritically celebrates the film’s auteur director—I merge the critical lenses of disability studies and postcolonial studies to examine it as an ableist white savior genre film. Drawing on archival research and considering L’Enfant sauvage’s narrative and production contexts, I explore how the film evokes what Snyder and Mitchell term the “Eugenic Atlantic”—the historical moment when racial and disability eugenics dovetailed at the end of the eighteenth century. The film not only maintains that the boy should be “civilized” in its representation of Itard as the narrative’s hero, but it also conflates disability and race via the following production and formal choices: the casting of a Romani boy (Jean-Pierre Cargol) despite Truffaut’s knowledge that the historical “wild child” was white; and the use of long and iris fade-out shots that work to distance the audience from identifying with the autistic child, most notably in scenes where he connects with nature as he stims (uses repetitive motions to self-stimulate). In its representation of autism-as-savagery only a year after May ’68—a key moment in postcolonial French history—L’Enfant sauvage reveals some of the ways in which colonialism and ableism are mutually imbricated historical methods of normalization that span centuries

Fast Color Quantization Using Weighted Sort-Means Clustering

Color quantization is an important operation with numerous applications in graphics and image processing. Most quantization methods are essentially based on data clustering algorithms. However, despite its popularity as a general purpose clustering algorithm, k-means has not received much respect in the color quantization literature because of its high computational requirements and sensitivity to initialization. In this paper, a fast color quantization method based on k-means is presented. The method involves several modifications to the conventional (batch) k-means algorithm including data reduction, sample weighting, and the use of triangle inequality to speed up the nearest neighbor search. Experiments on a diverse set of images demonstrate that, with the proposed modifications, k-means becomes very competitive with state-of-the-art color quantization methods in terms of both effectiveness and efficiency.Comment: 30 pages, 2 figures, 4 table

Histoplasmosis Cluster, Golf Course, Canada

We report a cluster of 4 cases of acute histoplasmosis (1 culture proven and 3 with positive serology, of which 2 were symptomatic) associated with exposure to soil during a golf course renovation. Patients in western Canada with compatible symptoms should be tested for histoplasmosis, regardless of their travel or exposure history

The secrets of T Pyxidis II. A recurrent nova that will not become a SN Ia

By various methods, we obtained L$_{disk}$ $\sim$ 70 L$_{\odot}$ and $\dot{M}$ $\sim$1.1 $\times$ 10$^{-8}$ M$_{\odot}$yr$^{-1}$. These values were about twice as high in the pre-1966-outburst epoch. This allowed the first direct estimate of the total mass accreted before outburst, M$_{accr}$=$\dot{M}_{pre-OB}$ $\cdot \Delta$t, and its comparison with the critical ignition mass M$_{ign}$. We found M$_{accr}$ and M$_{ign}$ to be in perfect agreement (with a value close to 5 $\times$ 10$^{-7}$M$_{\odot}$) for M$_1$ $\sim$ 1.37 M$_{\odot}$, which provides a confirmation of the thermonuclear runaway theory. The comparison of the observed parameters of the eruption phase, with the corresponding values in the grid of models by Yaron and collaborators, provides satisfactory agreement for values of M$_1$ close to 1.35 M$_{\odot}$ and log$\dot{M}$ between -8.0 and -7.0, but the observed value of the decay time t$_3$ is higher than expected. The long duration of the optically thick phase during the recorded outbursts of T Pyx, a spectroscopic behavior typical of classical novae, and the persistence of P Cyg profiles, constrains the ejected mass M$_{ign}$ to within 10$^{-5}$ - 10$^{-4}$ M$_{\odot}$. Therefore, T Pyx ejects far more material than it has accreted, and the mass of the white dwarf will not increase to the Chandrasekhar limit as generally believed in recurrent novae. A detailed study based on the UV data excludes the possibility that T Pyx belongs to the class of the supersoft X-ray sources, as has been postulated. XMM-NEWTON observations have revealed a weak, hard source and confirmed this interpretation

Improving the Performance of K-Means for Color Quantization

Color quantization is an important operation with many applications in graphics and image processing. Most quantization methods are essentially based on data clustering algorithms. However, despite its popularity as a general purpose clustering algorithm, k-means has not received much respect in the color quantization literature because of its high computational requirements and sensitivity to initialization. In this paper, we investigate the performance of k-means as a color quantizer. We implement fast and exact variants of k-means with several initialization schemes and then compare the resulting quantizers to some of the most popular quantizers in the literature. Experiments on a diverse set of images demonstrate that an efficient implementation of k-means with an appropriate initialization strategy can in fact serve as a very effective color quantizer.Comment: 26 pages, 4 figures, 13 table

Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the novel viral disease COVID-19. With no approved therapies, this pandemic illustrates the urgent need for broad-spectrum antiviral countermeasures against SARS-CoV-2 and future emerging CoVs. We report that remdesivir (RDV) potently inhibits SARS-CoV-2 replication in human lung cells and primary human airway epithelial cultures (EC50 = 0.01 μM). Weaker activity is observed in Vero E6 cells (EC50 = 1.65 μM) because of their low capacity to metabolize RDV. To rapidly evaluate in vivo efficacy, we engineered a chimeric SARS-CoV encoding the viral target of RDV, the RNA-dependent RNA polymerase of SARS-CoV-2. In mice infected with the chimeric virus, therapeutic RDV administration diminishes lung viral load and improves pulmonary function compared with vehicle-treated animals. These data demonstrate that RDV is potently active against SARS-CoV-2 in vitro and in vivo, supporting its further clinical testing for treatment of COVID-19

A systemic transformation of an arts and sciences curriculum to nurture inclusive excellence of all students through course-based research experiences

IntroductionWe describe herein a large-scale, multidisciplinary course-based undergraduate research experience program (CRE) developed at Lawrence Technological University (LTU). In our program, all students enrolled in CRE classes participate in authentic research experiences within the framework of the curriculum, eliminating self-selection processes and other barriers to traditional extracurricular research experiences.MethodsSince 2014, we have designed and implemented more than 40 CRE courses in our College of Arts and Sciences involving more than 30 instructors from computer science, mathematics, physics, biology, chemistry, English composition, literature, philosophy, media communication, nursing, and psychology.ResultsAssessment survey data indicates that students who participate in CRE courses have an enhanced attitude towards research and discovery, as well as increased self-efficacy. This intervention is particularly relevant for non-traditional students, such as students who commute and/or have significant work or childcare commitments, who often experience limited access to research activities.DiscussionHerein we highlight the importance of a systemic institutional change that has made this intervention sustainable and likely to outlast the external funding phase. Systemic change can emerge from a combination of conditions, including: (1) developing a critical mass of CRE courses by providing instructors with both incentives and training; (2) developing general principles on which instructors can base their CRE activities; (3) securing and maintaining institutional support to promote policy changes towards a more inclusive institution; and (4) diversifying the range of the intervention, both in terms of initiatives and disciplines involved

Internal control: Test your knowledge

The article presents a quiz aimed at helping companies improve their understanding of internal controls. Question topics include controls for faith-based organizations, the aim of internal control, enterprise risk management, controls for preventing duplicate payments, whether external auditors need to be familiar with a client\u27s internal controls, risks associated with financial reporting, the definition of control activities, and the monitoring component of the Committee of Sponsoring Organizations of the Treadway Commission

Leadership Challenges and Solutions over the Course of a Career

This interactive workshop will focus on challenges faced by women in leadership roles and women aspiring to leadership roles in the legal academy. Each of the three leaders – a law school dean, a full professor, and a newly tenured professor who also directs the legal clinic – will present relevant research that participants will apply to two hypothetical situations and then in small groups engage in a discussion of concrete reforms

Gender-Based Differences Of Partners In CPA Firms: Evidence From Kentucky

This paper investigates whether a relationship exists between situation-centered factors and the holding of partner status in a public accounting firm, and to determine if gender differences exist in the relationship between these variables. From a sample of 1227 Kentucky public accountants, it was found that the population of a county, number of other partners and associates in a firm, and years of experience are significantly related to the holding of partner status. However, women are less likely to be a partner in a firm with a larger number of associates and population does not appear to influence a womans chances of being a partner. The authors discuss the implications of these findings for practicing public accountants and provide suggestions for future research