364 research outputs found
Characterization of the evolution of noble metal particles in a commercial three‐way catalyst: Correlation between real and simulated ageing
Exomoon simulations
We introduce and describe our newly developed code that simulates light
curves and radial velocity curves for arbitrary transiting exoplanets with a
satellite. The most important feature of the program is the calculation of
radial velocity curves and the Rossiter-McLaughlin effect in such systems. We
discuss the possibilities for detecting the exomoons taking the abilities of
Extremely Large Telescopes into account. We show that satellites may be
detected also by their RM effect in the future, probably using less accurate
measurements than promised by the current instrumental developments. Thus, RM
effect will be an important observational tool in the exploration of exomoons.Comment: 5 pages, 2 figures with 9 figure panels, accepted by EM&
Virtual Noncontrast Abdominal Imaging with Photon-counting Detector CT.
Background Accurate CT attenuation and diagnostic quality of virtual noncontrast (VNC) images acquired with photon-counting detector (PCD) CT are needed to replace true noncontrast (TNC) scans. Purpose To assess the attenuation errors and image quality of VNC images from abdominal PCD CT compared with TNC images. Materials and Methods In this retrospective study, consecutive adult patients who underwent a triphasic examination with PCD CT from July 2021 to October 2021 were included. VNC images were reconstructed from arterial and portal venous phase CT. The absolute attenuation error of VNC compared with TNC images was measured in multiple structures by two readers. Then, two readers blinded to image reconstruction assessed the overall image quality, image noise, noise texture, and delineation of small structures using five-point discrete visual scales (5 = excellent, 1 = nondiagnostic). Overall image quality greater than or equal to 3 was deemed diagnostic. In a phantom, noise texture, spatial resolution, and detectability index were assessed. A detectability index greater than or equal to 5 indicated high diagnostic accuracy. Interreader agreement was evaluated using the Krippendorff α coefficient. The paired t test and Friedman test were applied to compare objective and subjective results. Results Overall, 100 patients (mean age, 72 years ± 10 [SD]; 81 men) were included. In patients, VNC image attenuation values were consistent between readers (α = .60), with errors less than 5 HU in 76% and less than 10 HU in 95% of measurements. There was no evidence of a difference in error of VNC images from arterial or portal venous phase CT (3.3 HU vs 3.5 HU, P = .16). Subjective image quality was rated lower in VNC images for all categories (all, P < .001). Diagnostic quality of VNC images was reached in 99% and 100% of patients for readers 1 and 2, respectively. In the phantom, VNC images exhibited 33% higher noise, blotchier noise texture, similar spatial resolution, and inferior but overall good image quality (detectability index >20) compared with TNC images. Conclusion Abdominal virtual noncontrast images from the arterial and portal venous phase of photon-counting detector CT yielded accurate CT attenuation and good image quality compared with true noncontrast images. © RSNA, 2022 Online supplemental material is available for this article See also the editorial by Sosna in this issue
A Case Study of Low-Mass Star Formation
This article synthesizes observational data from an extensive program aimed
toward a comprehensive understanding of star formation in a low-mass
star-forming molecular cloud. New observations and published data spanning from
the centimeter wave band to the near infrared reveal the high and low density
molecular gas, dust, and pre-main sequence stars in L1551.Comment: 24 pages, 21 figures, ApJS accepte
Severe hepatic sinusoidal obstruction associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer
Background: In advanced metastatic colorectal adenocarcinoma, the addition of a neo-adjuvant systemic treatment to surgery might translate into a survival advantage, although this is yet to be confirmed by ongoing randomized trials. The objective of this study was to assess the effects of preoperative systemic chemotherapy on the morphology of non-tumoral liver. Patients and methods: A large series of surgically resected liver metastases (n = 153) was selected. Light microscopy, electron microscopy, and immunohistochemistry using antibodies against endothelial cells (CD31) and hepatic stellate cells (α-SM actin, CRBP-1) were performed to identify sinusoidal wall integrity. Results: We found that 44 (51%) of the 87 post-chemotherapic liver resection specimens had sinusoidal dilatation and hemorrhage, related to rupture of the sinusoidal barrier. In contrast, the 66 livers treated by surgery alone remained normal. In 21 out of the 44 post-chemotherapy patients (48%), perisinusoidal and veno-occlusive fibrosis also developed. Sinusoidal injury persisted several months after end of chemotherapy, and fibrosis may progress. Development of lesions was strongly correlated to the use of oxaliplatin; 34 out of 43 patients (78%) treated with this drug showed striking sinusoidal alterations. Conclusions: Systemic neo-adjuvant chemotherapy in metastatic colorectal cancer frequently causes morphological lesions involving hepatic microvasculature. Sinusoidal obstruction, complicated by perisinusoidal fibrosis and veno-occlusive lesion of the non-tumoral liver revealed by this study, should be included in the list of the adverse side-effects of colorectal systemic chemotherapy, in particular related to the use of oxaliplati
Observations of T-Tauri Stars using HST-GHRS: I. Far Ultraviolet Emission Lines
We have analyzed GHRS data of eight CTTS and one WTTS. The GHRS data consists
of spectral ranges 40 A wide centered on 1345, 1400, 1497, 1550, and 1900 A.
These UV spectra show strong SiIV, and CIV emission, and large quantities of
sharp (~40 km/s) H2 lines. All the H2 lines belong to the Lyman band and all
the observed lines are single peaked and optically thin. The averages of all
the H2 lines centroids for each star are negative which may indicate that they
come from an outflow. We interpret the emission in H2 as being due to
fluorescence, mostly by Ly_alpha, and identify seven excitation routes within 4
A of that line. We obtain column densities (10^12 to 10^15 cm^-2) and optical
depths (~1 or less) for each exciting transition. We conclude that the
populations are far from being in thermal equilibrium. We do not observe any
lines excited from the far blue wing of Ly_alpha, which implies that the
molecular features are excited by an absorbed profile. SiIV and CIV (corrected
for H2 emission) have widths of ~200 km/s, and an array of centroids
(blueshifted lines, centered, redshifted). These characteristics are difficult
to understand in the context of current models of the accretion shock. For DR
Tau we observe transient strong blueshifted emission, perhaps the a result of
reconnection events in the magnetosphere. We also see evidence of multiple
emission regions for the hot lines. While CIV is optically thin in most stars
in our sample, SiIV is not. However, CIV is a good predictor of SiIV and H2
emission. We conclude that most of the flux in the hot lines may be due to
accretion processes, but the line profiles can have multiple and variable
components.Comment: 67 pages, 19 figures, Accepted in Ap
Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery
Background: The purpose of the study was to characterize histological response to chemotherapy of hepatic colorectal metastases (HCRM), evaluate efficacy of different chemotherapies on histological response, and determine whether tumor regression grading (TRG) of HCRM predicts clinical outcome. Patients and methods: TRG was evaluated on 525 HCRM surgically resected from 181 patients, 112 pretreated with chemotherapy. Disease-free survival (DFS) and overall survival (OS) were correlated to TRG. Results: Tumor regression was characterized by fibrosis overgrowing on tumor cells, decreased necrosis, and tumor glands (if present) at the periphery of HCRM. With irinotecan/5-fluorouracil (5-FU), major (MjHR), partial (PHR), and no (NHR) histological tumor regression were observed in 17%, 13%, and 70% of patients, respectively. With oxaliplatin/5-FU, MjHR, PHR, and NHR were observed in 37%, 45%, and 18% of patients, respectively. Five patients, treated with oxaliplatin, had complete response in all their metastases. MjHR was associated with an improved 3-year DFS compared with PHR or NHR. MjHR and PHR were associated with an improved 5-year OS compared with NHR. Conclusion: Histological tumor regression of HCRM to chemotherapy corresponds to fibrosis overgrowth and not to increase of necrosis. TRG should be considered when evaluating efficacy of chemotherapy for HCRM. Histological tumor regression was most common among oxaliplatin-treated patients and associated with better clinical outcom
The expected performance of stellar parametrization with Gaia spectrophotometry
Gaia will obtain astrometry and spectrophotometry for essentially all sources
in the sky down to a broad band magnitude limit of G=20, an expected yield of
10^9 stars. Its main scientific objective is to reveal the formation and
evolution of our Galaxy through chemo-dynamical analysis. In addition to
inferring positions, parallaxes and proper motions from the astrometry, we must
also infer the astrophysical parameters of the stars from the
spectrophotometry, the BP/RP spectrum. Here we investigate the performance of
three different algorithms (SVM, ILIUM, Aeneas) for estimating the effective
temperature, line-of-sight interstellar extinction, metallicity and surface
gravity of A-M stars over a wide range of these parameters and over the full
magnitude range Gaia will observe (G=6-20mag). One of the algorithms, Aeneas,
infers the posterior probability density function over all parameters, and can
optionally take into account the parallax and the Hertzsprung-Russell diagram
to improve the estimates. For all algorithms the accuracy of estimation depends
on G and on the value of the parameters themselves, so a broad summary of
performance is only approximate. For stars at G=15 with less than two
magnitudes extinction, we expect to be able to estimate Teff to within 1%, logg
to 0.1-0.2dex, and [Fe/H] (for FGKM stars) to 0.1-0.2dex, just using the BP/RP
spectrum (mean absolute error statistics are quoted). Performance degrades at
larger extinctions, but not always by a large amount. Extinction can be
estimated to an accuracy of 0.05-0.2mag for stars across the full parameter
range with a priori unknown extinction between 0 and 10mag. Performance
degrades at fainter magnitudes, but even at G=19 we can estimate logg to better
than 0.2dex for all spectral types, and [Fe/H] to within 0.35dex for FGKM
stars, for extinctions below 1mag.Comment: MNRAS, in press. Minor corrections made in v
Observational Constraints on the Formation and Evolution of Binary Stars
We present a high spatial resolution UV to NIR survey of 44 young binary
stars in Taurus with separations of 10-1000 AU. The primary results include:
(1) The relative ages of binary star components are more similar than the
relative ages of randomly paired single stars, supporting coeval formation. (2)
Only one of the companion masses is substellar, and hence the apparent
overabundance of T Tauri star companions relative to main-sequence star
companions can not be explained by a wealth of substellar secondaries that
would have been missed in main-sequence surveys. (3) Roughly 10% of T Tauri
binary star components have very red NIR colors (K-L > 1.4) and unusually high
mass accretion rates. This phenomenon does not appear to be restricted to
binary systems, however, since a comparable fraction of single T Tauri stars
exhibit the same properties. (4) Although the disk lifetimes of single stars
are roughly equal to their stellar ages, the disk lifetimes of binary stars are
an order of magnitude less than their ages. (5) The accretion rates for both
single and binary T Tauri stars appear to be moderately mass dependent. (6)
Although most classical T Tauri star binaries retain both a circumprimary and a
circumsecondary disk, there are several systems with only a circumprimary disk.
Together with the relative accretion rates, this suggests that circumprimary
disks survive longer, on average, than circumsecondary disks. (7) The disk
lifetimes, mass ratios, and relative accretion signatures of the closest
binaries (10-100 AU) suggest that they are being replenished from a
circumbinary reservoir with low angular momentum. Overall, these results
support fragmentation as the dominant binary star formation mechanism.Comment: 67 pages including 11 figures, LaTeX2e, accepted for publication in
Ap
An Infrared/X-ray Survey for New Members of the Taurus Star-Forming Region
We present the results of a search for new members of the Taurus star-forming
region using data from the Spitzer Space Telescope and the XMM-Newton
Observatory. We have obtained optical and near-infrared spectra of 44 sources
that exhibit red Spitzer colors that are indicative of stars with circumstellar
disks and 51 candidate young stars that were identified by Scelsi and coworkers
using XMM-Newton. We also performed spectroscopy on four possible companions to
members of Taurus that were reported by Kraus and Hillenbrand. Through these
spectra, we have demonstrated the youth and membership of 41 sources, 10 of
which were independently confirmed as young stars by Scelsi and coworkers. Five
of the new Taurus members are likely to be brown dwarfs based on their late
spectral types (>M6). One of the brown dwarfs has a spectral type of L0, making
it the first known L-type member of Taurus and the least massive known member
of the region (M=4-7 M_Jup). Another brown dwarf exhibits a flat infrared
spectral energy distribution, which indicates that it could be in the
protostellar class I stage (star+disk+envelope). Upon inspection of archival
images from various observatories, we find that one of the new young stars has
a large edge-on disk (r=2.5=350 AU). The scattered light from this disk has
undergone significant variability on a time scale of days in optical images
from the Canada-France-Hawaii Telescope. Using the updated census of Taurus, we
have measured the initial mass function for the fields observed by XMM-Newton.
The resulting mass function is similar to previous ones that we have reported
for Taurus, showing a surplus of stars at spectral types of K7-M1 (0.6-0.8
M_sun) relative to other nearby star-forming regions like IC 348, Chamaeleon I,
and the Orion Nebula Cluster
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