3,648 research outputs found

    Evaluating Communication Tools and Increasing Fruit and Vegetable Consumption in Vermont Head Start Classrooms

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    Introduction: We designed a program for four Head Start classrooms that aimed to: 1) Provide classrooms a tool that would facilitate communication with families about nutrition, 2) Educate families about the MyMeal tool, and 3) Increase fruit and vegetable consumption by providing families with fresh fruits and vegetables Fruit and vegetables are important components of a healthy diet, and sufficient consumption helps reduce the risk of developing cardiovascular disease, cancer, diabetes and obesity. Eating behaviors during childhood are highly parentally influenced and function as the foundation for future eating patterns. Studies have shown that the extent to which fruits and vegetables are present and accessible in the home correlates with the amount of fruit and vegetables eaten by children.https://scholarworks.uvm.edu/comphp_gallery/1210/thumbnail.jp

    EXTRAÇÃO DE ALUMINATO DE EMBALAGENS PLÁSTICAS METALIZADAS

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    O elevado volume de resíduos sólidos gerados atualmente suscita uma busca pelo reaproveitamento desses materiais a fim de minimizar os impactos socioambientais a que estão vinculados. O presente trabalho tem como objetivo a reciclagem de embalagens plásticas metalizadas, advindas do resíduo sólido, através da extração de alumínio (porção metálica) dessas embalagens, possibilitando o reaproveitamento das suas partes metálicas e poliméricas. A extração foi realizada imergindo-se as embalagens em soluções de hidróxido de sódio, cuja concentração da solução e a massa de plástico foram variadas. Foi estudada uma relação para otimizar o tempo de extração do alumínio em solução. Obteve-se a partir do processo de extração soluções de aluminato de sódio, que podem ser reutilizadas como coagulante para tratar águas residuárias de origem industrial. E o polímero resultante pode ser reutilizado como matéria prima na fabricação de novos produtos. Dessa forma, torna-se possível o reaproveitamento integral dessas embalagens, inserindo-as novamente ao ciclo produtivo.

    DIVULGANDO QUÍMICA, FÍSICA E ASTRONOMIA POR MEIO DE HISTÓRIAS EM QUADRINHOS

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    Este trabalho trata da elaboração, aplicação e análise de impacto de histórias em quadrinhos, com objetivo de popularizar conteúdos da Química, Física e Astronomia. O material foi integralmente elaborado pelos autores, sendo a personagem principal uma caricatura da primeira autora deste artigo. Todas as histórias foram desenvolvidas baseando-se em um enredo comum: pessoas que, durante atividades cotidianas, se depararam com fenômenos científicos, os quais são sequencialmente elucidados pela protagonista. O público-alvo selecionado para o desenvolvimento da pesquisa compreendeu quinze servidores do IFSP – SJC, excluindo-se professores e alunos. A pesquisa foi desenvolvida em três etapas: a aplicação de um formulário prévio (caracterização do público-alvo), a aplicação das histórias em quadrinhos produzidas e a aplicação de um formulário final (avaliação do impacto do material). Além disso, o formulário final serviu como um instrumento avaliativo dos quadrinhos, deixando-se aberto para que os entrevistados sugerissem alterações e avaliassem o material. 73% dos entrevistados alegaram ter aprendido bastante com a aplicação do material, 47% atribuíram nota 8 para o material e 46% atribuíram nota entre 9 e 10, evidenciando que o material foi bem recebido pelo público e que se enquadrou dentro dos objetivos esperados, mostrando-se principalmente como um facilitador do acesso aos conteúdos abordados. Palavras-chave: divulgação científica, histórias em quadrinhos, Física, Química, Astronomia

    Improved X-ray detection and particle identification with avalanche photodiodes

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    Avalanche photodiodes are commonly used as detectors for low energy x-rays. In this work we report on a fitting technique used to account for different detector responses resulting from photo absorption in the various APD layers. The use of this technique results in an improvement of the energy resolution at 8.2 keV by up to a factor of 2, and corrects the timing information by up to 25 ns to account for space dependent electron drift time. In addition, this waveform analysis is used for particle identification, e.g. to distinguish between x-rays and MeV electrons in our experiment.Comment: 6 pages, 6 figure

    Insight into the sulfur metabolism of Desulfurella amilsii by differential proteomics

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    Many questions regarding proteins involved in microbial sulfur metabolism remain unsolved. For sulfur respiration at low pH, the terminal electron acceptor is still unclear. Desulfurella amilsii is a sulfur-reducing bacterium that respires elemental sulfur (S0) or thiosulfate, and grows by S0 disproportionation. Due to its versatility, comparative studies on D. amilsii may shed light on microbial sulfur metabolism. Requirement of physical contact between cells and S0 was analyzed. Sulfide production decreased by around 50\% when S0 was trapped in dialysis membranes, suggesting that contact between cells and S0 is beneficial, but not strictly needed. Proteome analysis was performed under the aforementioned conditions. A Mo-oxidoreductase suggested from genome analysis to act as sulfur reductase was not detected in any growth condition. Thiosulfate and sulfite reductases showed increased abundance in thiosulfate-reducing cultures, while rhodanese-like sulfurtransferases were highly abundant in all conditions. DsrE and DsrL were abundantly detected during thiosulfate reduction, suggesting a modified mechanism of sulfite reduction. Proteogenomics suggest a different disproportionation pathway from what has been reported. This work points to an important role of rhodaneses in sulfur processes and these proteins should be considered in searches for sulfur metabolism in broader fields like meta-omics.This research was supported by the organization of the Brazilian Government for the development of Science and Technology CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico), by ERC project 323009 and a Gravitation project from the Netherlands Ministry of Education, Culture and Science (024.002.002). The authors thank Monika Jarzembowska (WUR, Wageningen, The Netherlands) for the support with the scanning electron microscopy analysisinfo:eu-repo/semantics/publishedVersio

    Multi-scale spatio-temporal analysis of human mobility

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    The recent availability of digital traces generated by phone calls and online logins has significantly increased the scientific understanding of human mobility. Until now, however, limited data resolution and coverage have hindered a coherent description of human displacements across different spatial and temporal scales. Here, we characterise mobility behaviour across several orders of magnitude by analysing ∼850 individuals' digital traces sampled every ∼16 seconds for 25 months with ∼10 meters spatial resolution. We show that the distributions of distances and waiting times between consecutive locations are best described by log-normal and gamma distributions, respectively, and that natural time-scales emerge from the regularity of human mobility. We point out that log-normal distributions also characterise the patterns of discovery of new places, implying that they are not a simple consequence of the routine of modern life

    Properties and controlled release of chitosan microencapsulated limonene oil

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    Chitosan microcapsules containing limonene essential oil as active ingredient were prepared by coacervation using three different concentrations of NaOH (0.50, 1.00, 1.45 wt%) and fixed concentrations of chitosan and surfactant of 0.50 wt%. The produced microcapsules were fully characterized in their morphology and chemical composition, and the kinetic release analysis of the active ingredient was evaluated after deposition in a non-woven cellulose fabric. The concentration of 1.00 and 1.45 wt% clearly show the best results in terms of dimension and shape of the microcapsules as well as in the volatility results. However, at the concentration of 1 wt% a higher number of microcapsules were produced as confirmed by FTIR and EDS analysis. Free microcapsules are spherical in size with disperse diameters between 2 and 12 μm. Immobilized microcapsules showed sizes from 4 to 7 μm, a rough surface and loss of spherical shape with pore formation in the chitosan walls. SEM analysis confirms that at higher NaOH concentrations, the larger the size of the microcapsules. This technique shows that by tuning NaOH concentration it is possible to efficiently control the release rate of encapsulated active agents demonstrating great potential as insect repellent for textiles.JMS and ALC acknowledge CAPES Foundation, the Ministry of Education of Brazil, Proc. no 8976/13-9 e Proc. No 1071/13-0, respectively, and the Department of Textile Engineering of the University of Minho, Portugal. J. Molina is grateful to the Conselleria d'Educacio, Formacio i Ocupacio (Generalitat Valenciana) for the Programa VALi+D Postdoctoral Fellowship. AZ (C2011-UMINHO-2C2T-01) acknowledges funding from Programa Compromisso para a Ciencia 2008, Portugal. Shafagh Dinparast Tohidi would like to thank the Portuguese Foundation of Science and Technology for providing the PhD grant SFRH/BD/94759/2013

    Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

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    Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN

    Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

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    This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin

    Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

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    Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts
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