UMA PROPOSTA DE PLANEJAMENTO DE ENSINO DE LÍNGUA INGLESA EM TORNO DE GÊNEROS TEXTUAIS

As English teachers of different teaching realities and researchers of the sociodiscursive interactionism perspective, we produced a didactic collection to Ensino Fundamental II. Therefore, for each school year we developed seven didactic sequences using a range of text genres, aiming at giving students the chance to broaden the possibility of social participation through the study of authentic texts and the development of practical activities. In this article, we are going to revisit the theoretical bases of our pedagogical proposal in order to make clear the paths taken and present our planning proposal for English teaching.Como  professores  de  língua  inglesa  de  diferentes  espaços  de  ensino  e pesquisadores da linha Interacionista Sociodiscursiva, nos propusemos a produzir uma coleção didática para o Ensino Fundamental II. assim, para cada ano escolar, elaboramos sete sequências didáticas usando gêneros textuais variados, visando possibilitar que o aluno, por meio do estudo de textos autênticos e do desenvolvimento de atividades práticas, amplie suas possibilidades de participação social, tanto pelo aprendizado da língua inglesa quanto pelas reflexões proporcionadas durante os trabalhos. Nesse artigo, retomaremos os pressupostos teóricos subjacentes a nossa proposta pedagógica para explicitar com mais clareza os caminhos trilhados e apresentar nossa proposta de planejamento de ensino

Biseugenol Exhibited Anti-Inflammatory and Anti-Asthmatic Effects in an Asthma Mouse Model of Mixed-Granulocytic Asthma

In the present work, the anti-inflammatory and antiasthmatic potential of biseugenol, isolated as the main component from n-hexane extract from leaves of Nectandra leucantha and chemically prepared using oxidative coupling from eugenol, was evaluated in an experimental model of mixed-granulocytic asthma. Initially, in silico studies of biseugenol showed good predictions for drug-likeness, with adherence to Lipinski’s rules of five (RO5), good Absorption, Distribution, Metabolism and Excretion (ADME) properties and no alerts for Pan-Assay Interference Compounds (PAINS), indicating adequate adherence to perform in vivo assays. Biseugenol (20 mg·kg−1) was thus administered intraperitoneally (four days of treatment) and resulted in a significant reduction in both eosinophils and neutrophils of bronchoalveolar lavage fluid in ovalbumin-sensitized mice with no statistical difference from dexamethasone (5 mg·kg−1). As for lung function parameters, biseugenol (20 mg·kg−1) significantly reduced airway and tissue damping in comparison to ovalbumin group, with similar efficacy to positive control dexamethasone. Airway hyperresponsiveness to intravenous methacholine was reduced with biseugenol but was inferior to dexamethasone in higher doses. In conclusion, biseugenol displayed antiasthmatic effects, as observed through the reduction of inflammation and airway hyperresponsiveness, with similar effects to dexamethasone, on mixed-granulocytic ovalbumin-sensitized miceFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)FAPESP: 2018/06088-

Percepção sobre qualidade de vida dos idosos de Portugal e do Brasil

Este estudo objetivou avaliar a percepção sobre qualidade de vida dos idosos de Portugal e do Brasile identificar a faceta do instrumento Whoqol-Old com maior escore avaliativo.Método:O estudo foi realizado com 508 idosos de Portugal e 349 idosos do Brasil. Para avaliação da qualidade de vida utilizou-se o instrumentoWhoqol-Old da OMS. Resultados:Identificou-se que as facetas com melhores escores avaliativos foram Família/Vida Familiar(74,05) para os idosos de Portugal e Morte e Morrer (75,37) para os idosos do Brasil.Conclusão:Os idosos que participaram deste estudo, tanto em Portugal quanto no Brasil, percepcionaram positivamente a sua qualidade de vida.Objective:This study aimed to evaluate the perception of life quality of the elderly in Portugal and Brazil, and to identify the facet of the WHOQOL-Old instrument with a higher evaluation score. Method:The study was conducted with 508 elderly from Portugal and 349elderly from Brazil. To evaluate the quality of life it was used the WHOQOL-Old instrument of WHO. Results:It was found that the facets with the best evaluative scores were Family/ FamilyLife(74.05) for the elderly in Portugal and DeathandDying(75.37) for the elderly in Brazil. Conclusion:The elderly in this study, both in Portugal and in Brazil, positively perceived their quality of life.Objetivo:Este estudio ha objetivado evaluar la percepción sobre calidad de vida de los viejos de Portugal y Brasil e identificar la faceta del instrumento WHOQOL-OLD con mayor puntuación de evaluación. Método:El estudio ha sido realizado con 508 viejos en Portugal y 349 en Brasil. Para evaluación de calidad de vida se ha utilizado el instrumento WHOQOL-OLD. Resultados:Se ha identificado que las facetas con mejores puntuaciones de evaluación han sido Familia/Vida familiar (74,05) para los de Portugal y Muerte y Morir (75,37) para los de Brasil. Conclusión:Los que han participado de este estudio, tanto en Portugal cuanto en Brasil, han tenido una percepción positiva en su calidad de vida.info:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Anais do V Encontro Brasileiro de Educomunicação: Educação midiática e políticas públicas

A presente coletânea, que chega ao público através de um suporte digital, tem como objetivo disponibilizar os papers, bem como os relatos de experiências educomunicativas apresentados durante o V ENCONTRO BRASILEIRO DE EDUCOMUNICAÇÃO, que teve como tema central: “Educação Midiática e Políticas Públicas”. O evento foi realizado em São Paulo, entre 19 e 21 de setembro de 2013, a partir de uma parceria entre o NCE/USP - Núcleo de Comunicação e Educação da USP, a Licenciatura em Educomunicação da ECA/USP, a ABPEducom – Associação Brasileira de Pesquisadores e Profissionais da Educomunicação e a FAPCOM – Faculdade Paulus de Tecnologia e Comunicação, que ofereceu seu campus, na Vila Mariana, para os atos do evento. Os presentes anais disponibilizam o texto de abertura, de autoria do coordenador geral do evento, denominado “Educação midiática e políticas públicas: vertentes históricas da emergência da Educomunicação na América Latina”. Na sequência, apresentam 61 papers sobre aspectos específicos da temática geral, resultantes de pesquisas na área, seguidos de 27 relatos de práticas educomunicativas, em nível nacional

Mapping density, diversity and species-richness of the Amazon tree flora

Using 2.046 botanically-inventoried tree plots across the largest tropical forest on Earth, we mapped tree species-diversity and tree species-richness at 0.1-degree resolution, and investigated drivers for diversity and richness. Using only location, stratified by forest type, as predictor, our spatial model, to the best of our knowledge, provides the most accurate map of tree diversity in Amazonia to date, explaining approximately 70% of the tree diversity and species-richness. Large soil-forest combinations determine a significant percentage of the variation in tree species-richness and tree alpha-diversity in Amazonian forest-plots. We suggest that the size and fragmentation of these systems drive their large-scale diversity patterns and hence local diversity. A model not using location but cumulative water deficit, tree density, and temperature seasonality explains 47% of the tree species-richness in the terra-firme forest in Amazonia. Over large areas across Amazonia, residuals of this relationship are small and poorly spatially structured, suggesting that much of the residual variation may be local. The Guyana Shield area has consistently negative residuals, showing that this area has lower tree species-richness than expected by our models. We provide extensive plot meta-data, including tree density, tree alpha-diversity and tree species-richness results and gridded maps at 0.1-degree resolution

Educomunicação e suas áreas de intervenção: Novos paradigmas para o diálogo intercultural

oai:omp.abpeducom.org.br:publicationFormat/1O material aqui divulgado representa, em essência, a contribuição do VII Encontro Brasileiro de Educomunicação ao V Global MIL Week, da UNESCO, ocorrido na ECA/USP, entre 3 e 5 de novembro de 2016. Estamos diante de um conjunto de 104 papers executivos, com uma média de entre 7 e 10 páginas, cada um. Com este rico e abundante material, chegamos ao sétimo e-book publicado pela ABPEducom, em seus seis primeiros anos de existência. A especificidade desta obra é a de trazer as “Áreas de Intervenção” do campo da Educomunicação, colocando-as a serviço de uma meta essencial ao agir educomunicativo: o diálogo intercultural, trabalhado na linha do tema geral do evento internacional: Media and Information Literacy: New Paradigms for Intercultural Dialogue

The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability

Chromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (ii) ≈500 ORFs for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) wide-spread utilization of quorum sensing for control of inducible systems, all of which underpin the versatility and adaptability of the organism. The genome also contains extensive but incomplete arrays of ORFs coding for proteins associated with mammalian pathogenicity, possibly involved in the occasional but often fatal cases of human C. violaceum infection. There is, in addition, a series of previously unknown but important enzymes and secondary metabolites including paraquat-inducible proteins, drug and heavy-metal-resistance proteins, multiple chitinases, and proteins for the detoxification of xenobiotics that may have biotechnological applications