120 research outputs found

    Fabricació d'un fibrociment altament sostenible a partir de residus de les indústries tèxtil i de la mineria

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    This project consists of manufacturing a highly sustainable fiber cement made of textile waste and mining industries and analyzing its properties.Aquest projecte consisteix en la fabricació d'un fibrociment altament sostenible a partir de residus de les indústries tèxtil i de la mineria i en analitzar les seves propietats.Este proyecto consiste en en la fabricación de un fibrocemento altamente sostenible a partir de residuos de las industrias textil y de la minería y en analizar sus propiedades.Objectius de Desenvolupament Sostenible::11 - Ciutats i Comunitats SosteniblesObjectius de Desenvolupament Sostenible::9 - Indústria, Innovació i Infraestructur

    El año milagroso de Einstein : movimiento, luz, whisky... y otros excesos

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    Fil: Cárdenas, Horacio. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Formación e Investigación en la Enseñanza de las Ciencias; Argentina.Fil: Gangui, Alejandro. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Formación e Investigación en la Enseñanza de las Ciencias; Argentina.Fil: Iglesias, María. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Formación e Investigación en la Enseñanza de las Ciencias; Argentina.Fil: Leschiutta, Ezequiel. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Formación e Investigación en la Enseñanza de las Ciencias; Argentina.Fil: Santamaria, Paula. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Formación e Investigación en la Enseñanza de las Ciencias; Argentina.Fue en 1905, entre los meses de marzo y septiembre, cuando luego de cumplir los 26 años Albert\nEinstein envió a publicar cinco trabajos que sacudieron los cimientos de la física y abrieron nuevas\nlíneas de investigación con un gran e insospechado futuro. Con un lenguaje práctico, este artículo\nrevela la obra del científico a través de la aplicación cotidiana de sus descubrimientos y nos acerca a\nuna faceta humana del gran genio del siglo pasado

    In Silico Exploration of Mycobacterium tuberculosis Metabolic Networks Shows Host-Associated Convergent Fluxomic Phenotypes

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    Mycobacterium tuberculosis, the causative agent of tuberculosis, is composed of several lineages characterized by a genome identity higher than 99%. Although the majority of the lineages are associated with humans, at least four lineages are adapted to other mammals, including different M. tuberculosis ecotypes. Host specificity is associated with higher virulence in its preferred host in ecotypes such as M. bovis. Deciphering what determines the preference of the host can reveal host-specific virulence patterns. However, it is not clear which genomic determinants might be influencing host specificity. In this study, we apply a combination of unsupervised and supervised classification methods on genomic data of ~27,000 M. tuberculosis clinical isolates to decipher host-specific genomic determinants. Host-specific genomic signatures are scarce beyond known lineage-specific mutations. Therefore, we integrated lineage-specific mutations into the iEK1011 2.0 genome-scale metabolic model to obtain lineage-specific versions of it. Flux distributions sampled from the solution spaces of these models can be accurately separated according to host association. This separation correlated with differences in cell wall processes, lipid, amino acid and carbon metabolic subsystems. These differences were observable when more than 95% of the samples had a specific growth rate significantly lower than the maximum achievable by the models. This suggests that these differences might manifest at low growth rate settings, such as the restrictive conditions M. tuberculosis suffers during macrophage infection

    FTIR-chemometric analytical methodology as a tool for clustering oils from centenarian olive trees grown in the Côa Valley region

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    The centenarian olive trees are part of the historical and cultural heritage of the Côa Valley region where a significant number of these specimens can be found. They have high importance in olive grove heritage; however, their genetic and phenotypic diversity is still poorly studied. Recently, Fourier Transform Infrared (FTIR) spectroscopy start to be widely used in several studies in the food field, becoming a powerful analytical tool for the analysis of edible oils and fats. This technique has numerous advantages, allowing a fast and non-destructive analysis, and requiring minimal sample preparation. In this context, FTIR has been applied to classify and identify different fats, detection of virgin olive oils adulteration, determination of trans fatty acids and evaluation of oil mixtures' composition in foods, all this based on the spectral profiles. Considering that there is a great diversity of centenarian olive trees in which the varieties are unknown, the objective of this work was to use the FTIR technique to identify groups of olive oils with similar chemical characteristics, thus reducing the time and required amount of samples for analysis.The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support by national funds FCT/MCTES to CIMO (UIDB/00690/2020) and to Associate Laboratory for Green Chemistry-LAQV (UIDB/50006/2020). Nuno Rodrigues and Aran Santamaria-Echar thanks to National funding by FCT- Foundation for Science and Technology, P.I., through the institutional scientific employment program-contract. This work was financially supported by the project “COA/BRB/0035/2019” OLIVECOA - Centenarian olive trees of Côa Valley region: rediscovering the past to valorise the future funded by the Foundation for Science and Technology (FCT, Portugal).info:eu-repo/semantics/publishedVersio

    Propolis application in food preservation: development of chitosan-based edible films

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    Edible films derived from chitosan highlight for its potential as coating packages, due to their antimicrobial activity and low oxygen permeability, while propolis has shown effective as a natural additive due to its antimicrobial and antioxidant properties. Thus, its combination to produce edible films, provides a promising approach to enhance the life spam of easily perishable foods. The present study describes the development of edible films based on chitosan produced from chitin extracted crawfish shell, modified with propolis. Chitosan-based films prepared incorporating different concentrations of poplar propolis extracts (0% to 20%), where characterized by FTIR, TGA and SEM. Additionally, mechanical properties, water-solubility, colour and optical transmittance tests were performed to assess the film specificities. The antioxidant and antimicrobial activity of the coating were also studied. The FTIR spectra of the extracted material enable the identification of all major peaks associated to chitosan, corroborating the extraction procedure of chitin/chitosan from crawfish. The addition of propolis to the films decreased the water solubility compared to control. Besides, all films exhibited antioxidant and antimicrobial activity. The output clear indicates that films enriched with propolis may be an alternative candidate for food packing.The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support by national funds FCT/MCTES to CIMO (UIDB/00690/2020). National funding by FCT- Foundation for Science and Technology, through the institutional scientific employment program-contract with Soraia I. Falcão.info:eu-repo/semantics/publishedVersio

    Simulación: un curso innovador en los estudios de Aeronáutica

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    Presentamos aquí una nueva metodología en la impartición de un curso de ciencias de la computación con énfasis particular en aspectos de dinámica de fluidos computacional (DFC) y las experiencias que se derivan de esta implementación. Las actividades principales que los estudiantes realizan en este curso son: el desarrollo de un proyecto inicial en la temática de ciencias de los materiales, la elaboración de un proyecto largo en DFC y una introducción al uso de un paquete de software específico de DFC. Los proyectos se realizan por grupos y consisten en la implementación (programación) de modelos matemáticos y una interfaz gráfica que permita la visualización de los resultados que se obtengan mediante la resolución numérica de los modelos considerados. La innovación en la asignatura se da en la utilización de técnicas de aprendizaje basado en proyectos o Project Based Learning y en el hecho que el curso es impartido de forma coordinada por varios profesores que provienen de áreas distintas. Otro aspecto novedoso lo constituye la oportunidad que presenta el curso para que los estudiantes redacten informes escritos, hagan presentaciones orales, utilicen el inglés y trabajen en un entorno Linux para el desarrollo de los proyectos.Postprint (published version

    Saponin-based natural nanoemulsions as alpha-tocopherol delivery systems for dermal applications

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    Nanoemulsions can be produced using simple methods and compounds from natural sources. They can increase water dispersibility and bioavailability and optimise active ingredient dispersion in particular skin layers. Lipophilic compounds of the vitamin E family (tocopherols and tocotrienols) are well-known for their high antioxidant activity and capacity to protect the skin from oxidative stress. In this context, oil-in-water (o/w) nanoemulsions with and without α-tocopherol (Vitamin E, VE) were formulated with two emulsifier alternatives, Quillaja saponin (QS), and a combination of QS with Tribulus terrestris (QSTT) (50/50, w/w). The emulsions were evaluated concerning stability, microstructure, droplet size, colour attributes, encapsulation efficiency, UV photostability, antioxidant activity, and in vitro permeation studies to assess the delivery potential. Results showed highly stable systems, with round-shape droplets of 80–121 nm size. QS and QSTT samples' colours were close to white and light brownish, respectively. The topical nano cream had the capacity to entrap VE, producing a protective effect from UV degradation, and very significant antioxidant activity, with IC50 values around 0.01 %wt. The skin permeation profiles showed the efficiency of the formulations in the delivery of VE, with permeabilities between 64 and 74 µg/cm2, while the control sample showed no VE permeation.info:eu-repo/semantics/publishedVersio

    Choroid Plexus Papilloma of the Fourth Ventricle: A Pediatric Patient.

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    Choroid plexus papilloma is a low-frequency entity in both the adult and pediatric populations. Its clinical presentation is very variable as it depends on its location and length. We must always do the differential diagnosis between papilloma and other intraventricular pathologies. This article is about a case report of a pediatric patient with a Choroid plexus papilloma located in the fourth ventricle, a location that is atypical for the pediatric population
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