456 research outputs found
Contrasting human perceptions of and attitudes towards two threatened small carnivores, Lycalopex fulvipes and Leopardus guigna, in rural communities adjacent to protected areas in Chile
Indexación: Scopus.The interaction between humans and small carnivores is a phenomenon especially frequent in rural fringes, as is the case of communities surrounding natural areas. In Chile, two species of threatened carnivores, the Darwin's Fox and the Guigna, have increased their contact with humans due to human-induced changes in their habitat. The objective of this study was to characterize the interactions of these species with humans by assessing human perceptions and attitudes toward them, and to assess livestock and poultry ownership and management practices in local communities to evaluate their possible roles in the phenomenon. We conducted semi-structured interviews in rural communities adjacent to natural protected areas of two different regions in southern Chile. We found that people have a more positive perception of Darwin's Foxes than Guignas, but both species are considered damaging due to poultry attacks. Livestock and poultry management was generally deficient. Improvements in animal management and education programs could lead to a significant decrease in negative interactions. © Sacristan et al. 2018.https://www.threatenedtaxa.org/index.php/JoTT/article/view/4030/442
What Matters Most to Patients and Rheumatologists? A Discrete Choice Experiment in Rheumatoid Arthritis
Introduction:
To determine patient and rheumatologist preferences for rheumatoid arthritis (RA) treatment attributes in Spain and to evaluate their attitude towards shared decision-making (SDM).
Methods:
Observational, descriptive, exploratory and cross-sectional study based on a discrete choice experiment (DCE). To identify the attributes and their levels, a literature review and two focus groups (patients [P] = 5; rheumatologists [R] = 4) were undertaken. Seven attributes with 2–4 levels were presented in eight scenarios. Attribute utility and relative importance (RI) were assessed using a conditional logit model. Patient preferences for SDM were assessed using an ad hoc questionnaire.
Results:
Ninety rheumatologists [52.2% women; mean years of experience 18.1 (SD: 9.0); seeing an average of 24.4 RA patients/week (SD: 15.3)] and 137 RA patients [mean age: 47.5 years (SD: 10.7); 84.0% women; mean time since diagnosis of RA: 14.2 years (SD: 11.8) and time in treatment: 13.2 years (SD: 11.2), mean HAQ score 1.2 (SD: 0.7)] participated in the study. In terms of RI, rheumatologists and RA patients viewed: time with optimal QoL: R: 23.41%/P: 35.05%; substantial symptom improvement: R: 13.15%/P: 3.62%; time to onset of treatment action: R: 16.24%/P: 13.56%; severe adverse events: R: 10.89%/P: 11.20%; mild adverse events: R: 4.16%/P: 0.91%; mode of administration: R: 25.23%/P: 25.00%; and added cost: R: 6.93%/P: 10.66%. Nearly 73% of RA patients were involved in treatment decision-making to a greater or lesser extent; however, 27.4% did not participate at all.
Conclusion:
Both for rheumatologists and patients, the top three decision-making drivers are time with optimal quality, treatment mode of administration and time to onset of action, although in different ranking order. Patients were willing to be more involved in the treatment decision-making process
Polarization-Resolved Near-Field Spectroscopy of Localized States in m-Plane InxGa1−xN/GaN Quantum Wells
Producción CientíficaWe present a polarization, spectrally, and spatially resolved near-field photoluminescence (PL) measurement technique and apply it to the study of wide m-plane InxGa1−xN/GaN quantum wells grown on on-axis and miscut GaN substrates. It is found that PL originates from localized states; nevertheless, its degree of linear polarization (DLP) is high with little spatial variation. This allows an unambiguous assignment of the localized states to InxGa1−xN composition-related band potential fluctuations. Spatial PL variations, occurring due to morphology features of the on-axis samples, play a secondary role compared to the variations of the alloy composition. The large PL peak wavelength difference for polarizations parallel and perpendicular to the c axis, the weak correlation between the peak PL wavelength and the DLP, and the temperature dependence of the DLP suggest that effective potential variations and the hole mass in the second valence-band level are considerably smaller than that for the first level. DLP maps for the long wavelength PL tails have revealed well-defined regions with a small DLP, which have been attributed to a partial strain relaxation around dislocations.Swedish Energy Agency (Contract No. 36652-1)Swedish Research Council (Contract No. 621-2013- 4096
EUPVSEC 2018
There are many characterization techniques available to evaluate the health of solar panels, such as I-V characterization, infrared thermography (IR), photoluminescence (PL) and electroluminescence (EL). EL imaging has become in recent years a powerful diagnostic tool to evaluate PV modules. EL images allow to detect several defects and degradation modes in the solar cells. The failures are observed as dark contrasted areas in the images. Broad dark regions can be detected even in a low resolution image, while a high resolution image is needed to detect some more specific problems such as cracks, multi-cracks or other line-shaped defects.PósterJunta de Castilla y León (programa de apoyo a proyectos de investigación - Ref. VA081U16)Ministerio de Economía, Industria y Competitividad (Proyect ENE2014-56069-C4-4-R
On natural metalinguistic abilities in aphasia: a preliminary study
Natural metalinguistic abilities, which are put into play without explicit instructions, constitute the cognitive basis for a 'reflexive' use of language, a particular manifestation of the executive function when applied to language and verbal behaviour. This reflexive use entails a specific attentional activity by speakers and hearers with regard to linguistic outputs, and an intentional experience-based control over the language use. Putting into play natural metalinguistic abilities can be considered a significant factor for explaining different kinds of adaptive processes. Our results permit us to conclude that an impairment of metalinguistic abilities is involved in aphasia to different degrees. Moreover, the examination of preserved metalinguistic abilities provides an alternative way for assessing the degree of severity of impaired communicative behaviour by people with aphasia. Our procedure, presumably, will also be useful for suggesting new factors when designing therapeutic programmes
Comprehensive overview of the analytical methods for determining pyrrolizidine alkaloids and their derived oxides in foods
Producción CientíficaPyrrolizidine alkaloids and their derived oxides are toxins naturally produced by plants when they are exposed to stress factors. In particular, the unsaturated pyrrolizidine alkaloids exhibiting a double bond between the 1,2-positions have caused great interest in recent years since they have pneumotoxic, genotoxic and carcinogenic effects upon ingestion. In this review, focus on their chemical structure justifying their toxicity is provided as well as insight on the recently adopted EU regulatory framework. In addition, to reveal current trends and highlight the research effort in the field, an all-time bibliometric analysis was performed for the first time. It was found that tea, infusions, honey, spices, and cereals are the most common foodstuffs in which pyrrolizidine alkaloids have been detected. In terms of pre-analytical steps, the application of efficient sample preparation is necessary to detect pyrrolizidine alkaloids in complex food matrices. Solvent extraction followed by a clean-up stage, e.g., solid-phase extraction was the most applied option. Focusing on the analytical methods, liquid chromatography combined with various mass spectrometry detectors has been the golden standard in the field. Gas chromatography methods were also applied, but the need for analyte derivatisation has hindered their application. All in all, this review provides an overview on the analysis of pyrrolizidine alkaloids and their derived oxides, comprehensively discussing the up-to-date advances and highlighting the analytical challenges to be faced.METROFOOD-CZ research infrastructure project (MEYS Grant No: LM2018100
Occurrence and Quantification of Antimicrobial Resistance Genes in the Gastrointestinal Microbiome of Two Wild Seabird Species With Contrasting Behaviors
Indexación ScopusAntimicrobial resistance genes (ARGs) are environmental pollutants and anthropization indicators. We evaluated human interference in the marine ecosystem through the ocurrence and quantification (real-time PCRs) of 21 plasmid-mediated ARGs in enema samples of 25 wild seabirds, upon admission into rehabilitation: kelp gull (Larus dominicanus, n = 14) and Magellanic penguin (Spheniscus magellanicus, n = 11). Overall, higher resistance values were observed in kelp gulls (non-migratory coastal synanthropic) in comparison with Magellanic penguins (migratory pelagic non-synanthropic). There were significant differences between species (respectively, kelp gull and Magellanic penguin): ARGs occurrence (blaTEM [p = 0.032]; tetM [p = 0.015]; tetA [p = 0.003]; and sulII [p = 0.007]), mean number of ARGs per sample (p = 0.031), ARGs mean load percentage (aadA [p = 0.045], tetA [p = 0.031], tetM [p = 0.016], blaTEM [p = 0.032], sulII [p = 0.008]), percentage of genes conferring resistance to an antimicrobial class (betalactams [p = 0.036] and sulfonamides [p = 0.033]), mean number of genes conferring resistance to one or more antimicrobial classes (p = 0.024]), percentage of multiresistant microbiomes (p = 0.032), and clustering (p = 0.006). These differences are likely due to these species' contrasting biology and ecology - key factors in the epidemiology of ARGs in seabirds. Additionally, this is the first report of mecA in seabirds in the Americas. Further studies are necessary to clarify the occurrence and diversity of ARGs in seabirds, and their role as potential sources of infection and dispersal within the One Health chain of ARGs. © Copyright © 2021 Ewbank, Esperón, Sacristán, Sacristán, Neves, Costa-Silva, Antonelli, Rocha Lorenço, Kolesnikovas and Catão-Dias.https://www.frontiersin.org/articles/10.3389/fvets.2021.651781/ful
Cross-species transmission of retroviruses among domestic and wild felids in human-occupied landscapes in Chile
Human transformation of natural habitats facilitates pathogen transmission between domestic and wild species. The guigna (Leopardus guigna), a small felid found in Chile, has experienced habitat loss and an increased probability of contact with domestic cats. Here, we describe the interspecific transmission of feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) between domestic cats and guignas and assess its correlation with human landscape perturbation. Blood and tissue samples from 102 free-ranging guignas and 262 domestic cats were collected and analyzed by PCR and sequencing. Guigna and domestic cat FeLV and FIV prevalence were very similar. Phylogenetic analysis showed guigna FeLV and FIV sequences are positioned within worldwide domestic cat virus clades with high nucleotide similarity. Guigna FeLV infection was significantly associated with fragmented landscapes with resident domestic cats. There was little evidence of clinical signs of disease in guignas. Our results contribute to the understanding of the implications of landscape perturbation and emerging diseases
Alternative polyadenylation and salicylic acid modulate root responses to low nitrogen availability
Nitrogen (N) is probably the most important macronutrient and its scarcity limits plant growth, development and fitness. N starvation response has been largely studied by transcriptomic analyses, but little is known about the role of alternative polyadenylation (APA) in such response. In this work, we show that N starvation modifies poly(A) usage in a large number of transcripts, some of them mediated by FIP1, a component of the polyadenylation machinery. Interestingly, the number of mRNAs isoforms with poly(A) tags located in protein-coding regions or 5 '-UTRs significantly increases in response to N starvation. The set of genes affected by APA in response to N deficiency is enriched in N-metabolism, oxidation-reduction processes, response to stresses, and hormone responses, among others. A hormone profile analysis shows that the levels of salicylic acid (SA), a phytohormone that reduces nitrate accumulation and root growth, increase significantly upon N starvation. Meta-analyses of APA-affected and fip1-2-deregulated genes indicate a connection between the nitrogen starvation response and salicylic acid (SA) signaling. Genetic analyses show that SA may be important for preventing the overgrowth of the root system in low N environments. This work provides new insights on how plants interconnect different pathways, such as defense-related hormonal signaling and the regulation of genomic information by APA, to fine-tune the response to low N availability
Educação, conflito e convivência democrática
Após uma caracterização sucinta da actual condição pós-moderna, serão desenvolvidas
algumas questões que, pela sua relevância actual no campo da educação,
merecem ser revisitadas de modo crítico, nomeadamente, e num primeiro momento,
a escola, o conflito e a convivência. Num segundo momento, apontar-se-ão algumas
características da escola que fazem dela uma organização com alguma perversidade,
hipocrisia e irracionalidade. O último aspecto a ser tratado irá compreender
a escola como organização comunicacional ou organização convivencial, onde os
conceitos de disciplina, violência, conflito e convivência assumem um sentido mais
profundamente democrático.After a succinct characterization of the current postmodern condition, some
questions might be developed, because of its current relevance in the education
field, they must to be reviewed in a critical way, namely, and firstly, the school, the
conflict and the conviviality. Secondly, this article underlines some school’s
characteristics that turns it into an organization with a little perversity, hypocrisy
and irrationality. The last aspect to be treated is the understanding of the school as
a communicative or convivial organization, in which the concepts of discipline,
violence, conflict and conviviality assume a more democratic orientation.Enseguida a una caracterización sucinta de la actual condición pos-moderna,
serán desarrolladas algunas cuestiones que, por su relevancia actual en el campo
de la educación, merecen ser visitadas de modo crítico, nombradamente, y en
primero momento, la escuela, el conflicto y la convivencia. En segundo momento,
se apuntarán algunas características de la escuela que la hacen una organización
con alguna perversidad, hipocresía e irracionalidad. El último aspecto a ser tratado irá comprender la escuela como organización de comunicación u
organización de convivencia, donde los conceptos de disciplina, violencia,
conflicto e convivencia asumen un sentido más profundamente democrático.(undefined
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