174 research outputs found
Boson gas in a periodic array of tubes
We report the thermodynamic properties of an ideal boson gas confined in an
infinite periodic array of channels modeled by two, mutually perpendicular,
Kronig-Penney delta-potentials. The particle's motion is hindered in the x-y
directions, allowing tunneling of particles through the walls, while no
confinement along the z direction is considered. It is shown that there exists
a finite Bose- Einstein condensation (BEC) critical temperature Tc that
decreases monotonically from the 3D ideal boson gas (IBG) value as the
strength of confinement is increased while keeping the channel's cross
section, constant. In contrast, Tc is a non-monotonic function of
the cross-section area for fixed . In addition to the BEC cusp, the
specific heat exhibits a set of maxima and minima. The minimum located at the
highest temperature is a clear signal of the confinement effect which occurs
when the boson wavelength is twice the cross-section side size. This
confinement is amplified when the wall strength is increased until a
dimensional crossover from 3D to 1D is produced. Some of these features in the
specific heat obtained from this simple model can be related, qualitatively, to
at least two different experimental situations: He adsorbed within the
interstitial channels of a bundle of carbon nanotubes and
superconductor-multistrand-wires NbSn.Comment: 9 pages, 10 figures, submitte
The dinophycean genus Azadinium and related species – morphological and molecular characterization, biogeography, and toxins
Peer-reviewed.Azaspiracids (AZAs) are the most recently discovered group of lipophilic marine biotoxins of microalgal origin. It took about twelve years from the first human poisoning event until a culprit for AZA production was unambiguously identified and described as a novel species, Azadinium spinosum, within a newly created genus. Since then, knowledge on the genus has increased considerably, and an update on the current circumscription of the genus is presented here including various aspects of morphology, phylogeny, biogeography, and toxin production. There are currently five described species: A. spinosum, A. obesum, A. poporum, A. caudatum, and A. polongum. As indicated by molecular sequence variation detected in field samples, there are probably more species to recognize. Moreover, Amphidoma languida has been described recently, and this species is the closest relative of Azadinium based on both molecular and morphological data. Amphidoma and Azadinium are now grouped in the family Amphidomataceae, which forms an independent lineage among other monophyletic major groups of dinophytes. Initially, azaspiracids have been detected in A. spinosum only, but AZA production within the Amphidomataceae appears complex and diverse: A new type of azaspiracid, with a number of structural variants, has been detected in A. poporum and Amphidoma languida, and AZA-2 has now been detected in Chinese strains of A. poporum
Topological and geometrical restrictions, free-boundary problems and self-gravitating fluids
Let (P1) be certain elliptic free-boundary problem on a Riemannian manifold
(M,g). In this paper we study the restrictions on the topology and geometry of
the fibres (the level sets) of the solutions f to (P1). We give a technique
based on certain remarkable property of the fibres (the analytic representation
property) for going from the initial PDE to a global analytical
characterization of the fibres (the equilibrium partition condition). We study
this analytical characterization and obtain several topological and geometrical
properties that the fibres of the solutions must possess, depending on the
topology of M and the metric tensor g. We apply these results to the classical
problem in physics of classifying the equilibrium shapes of both Newtonian and
relativistic static self-gravitating fluids. We also suggest a relationship
with the isometries of a Riemannian manifold.Comment: 36 pages. In this new version the analytic representation hypothesis
is proved. Please address all correspondence to D. Peralta-Sala
Biology of Bemisia tabaci (Genn.) B-biotype and parasitism by Encarsia formosa (Gahan) on collard, soybean and tomato plants
Genetic signatures of parental contribution in black and white populations in Brazil
Two hundred and three individuals classified as white were tested for 11 single nucleotide polymorphisms plus two insertion/deletions in their Y-chromosomes. A subset of these individuals (n = 172) was also screened for sequences in the first hypervariable segment of their mitochondrial DNA (mtDNA). In addition, complementary studies were done for 11 of the 13 markers indicated above in 54 of 107 black subjects previously investigated in this southern Brazilian population. The prevalence of Y-chromosome haplogroups among whites was similar to that found in the Azores (Portugal) or Spain, but not to that of other European countries. About half of the European or African mtDNA haplogroups of these individuals were related to their places of origin, but not their Amerindian counterparts. Persons classified in these two categories of skin color and related morphological traits showed distinct genomic ancestries through the country. These findings emphasize the need to consider in Brazil, despite some general trends, a notable heterogeneity in the pattern of admixture dynamics within and between populations/groups
PHENOLIC COMPOSITION AND ANTIOXIDANT CAPACITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF BLACKBERRIES
Identification of regulatory variants associated with genetic susceptibility to meningococcal disease
Non-coding genetic variants play an important role in driving susceptibility to complex diseases but their characterization remains challenging. Here, we employed a novel approach to interrogate the genetic risk of such polymorphisms in a more systematic way by targeting specific regulatory regions relevant for the phenotype studied. We applied this method to meningococcal disease susceptibility, using the DNA binding pattern of RELA - a NF-kB subunit, master regulator of the response to infection - under bacterial stimuli in nasopharyngeal epithelial cells. We designed a custom panel to cover these RELA binding sites and used it for targeted sequencing in cases and controls. Variant calling and association analysis were performed followed by validation of candidate polymorphisms by genotyping in three independent cohorts. We identified two new polymorphisms, rs4823231 and rs11913168, showing signs of association with meningococcal disease susceptibility. In addition, using our genomic data as well as publicly available resources, we found evidences for these SNPs to have potential regulatory effects on ATXN10 and LIF genes respectively. The variants and related candidate genes are relevant for infectious diseases and may have important contribution for meningococcal disease pathology. Finally, we described a novel genetic association approach that could be applied to other phenotypes
Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362
First M87 Event Horizon Telescope results. IX.: detection of near-horizon circular polarization
Galaxie
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