Pilot study to evaluate a tailored text message intervention for pregnant smokers (MiQuit): study protocol for a randomised controlled trial.

Background: Smoking in pregnancy is a public health problem. Self-help smoking cessation support can help pregnant women to stop smoking, but the effects of delivering this kind of support via SMS text message are not known. A previous randomised controlled trial (RCT) demonstrated the feasibility and acceptability of providing such support to pregnant smokers using an automated, tailored text message intervention called MiQuit. This larger RCT will estimate key parameters for and will test the feasibility of delivering a major trial run within the United Kingdom National Health Service settings aimed at providing definitive evidence on the utility of MiQuit for helping pregnant smokers to stop. Methods/Design: This will be a multi-centre, parallel group RCT. Participants are being identified in 16 English antenatal care settings and must be >16 years old, pregnant, 1 daily cigarette, have smoked >5 daily cigarettes before pregnancy, and able to understand texts in English. After consenting and the collection of baseline data, participants are randomised to control or intervention groups in a 1:1 ratio; randomisation is stratified by trial site and gestation and employs computer-generated pseudo-random code using random permuted blocks of randomly varying size, and held on a secure server. All participants receive a National Health Service (NHS) leaflet aimed at helping them to stop smoking. Intervention group women also receive the 12-week MiQuit programme of tailored, supportive, interactive text message, self-help cessation support. Women are followed up by telephone 4 weeks after randomisation and at 36 weeks gestation. The study aims to recruit 400 women, and with this sample we will be able to estimate trial centres’ recruitment rates to within +/−1% (margin of error = half width of 95% confidence interval); individual trial groups’ ascertainment of rates for smoking outcomes between 4 weeks after randomisation until approximately 36 weeks gestation to within +/−4%, and across both groups, the combined cessation rate at 36 weeks +/−3%. Discussion: Pilot trial completion will provide data to facilitate planning for a definitive trial investigating whether MiQuit works for smoking cessation in pregnancy. Trial registration: ClinicalTrials.gov NCT02043509 Registered 14 January 2014

Inter-Disciplinary Validation of Pre Earthquake Signals. Case Study for Major Earthquakes in Asia (2004-2010) and for 2011 Tohoku Earthquake

We carried out multi-sensors observations in our investigation of phenomena preceding major earthquakes. Our approach is based on a systematic analysis of several physical and environmental parameters, which we found, associated with the earthquake processes: thermal infrared radiation, temperature and concentration of electrons in the ionosphere, radon/ion activities, and air temperature/humidity in the atmosphere. We used satellite and ground observations and interpreted them with the Lithosphere-Atmosphere- Ionosphere Coupling (LAIC) model, one of possible paradigms we study and support. We made two independent continues hind-cast investigations in Taiwan and Japan for total of 102 earthquakes (M>6) occurring from 2004-2011. We analyzed: (1) ionospheric electromagnetic radiation, plasma and energetic electron measurements from DEMETER (2) emitted long-wavelength radiation (OLR) from NOAA/AVHRR and NASA/EOS; (3) radon/ion variations (in situ data); and 4) GPS Total Electron Content (TEC) measurements collected from space and ground based observations. This joint analysis of ground and satellite data has shown that one to six (or more) days prior to the largest earthquakes there were anomalies in all of the analyzed physical observations. For the latest March 11 , 2011 Tohoku earthquake, our analysis shows again the same relationship between several independent observations characterizing the lithosphere /atmosphere coupling. On March 7th we found a rapid increase of emitted infrared radiation observed from satellite data and subsequently an anomaly developed near the epicenter. The GPS/TEC data indicated an increase and variation in electron density reaching a maximum value on March 8. Beginning from this day we confirmed an abnormal TEC variation over the epicenter in the lower ionosphere. These findings revealed the existence of atmospheric and ionospheric phenomena occurring prior to the 2011 Tohoku earthquake, which indicated new evidence of a distinct coupling between the lithosphere and atmosphere/ionosphere

Phenomena of electrostatic perturbations before strong earthquakes (2005–2010) observed on DEMETER

International audienceDuring the DEMETER operating period in 2004– 2010, many strong earthquakes took place in the world. 69 strong earthquakes with a magnitude above 7.0 during January 2005 to February 2010 were collected and analysed. The orbits, recorded in local nighttime by satellite, were chosen by a distance of 2000 km to the epicentres during the 9 days around these earthquakes, with 7 days before and 1 day after. The anomaly is defined when the disturbances in the electric field PSD increased to at least 1 order of magnitude relative to the normal median level about 10 −2 µV 2 /m 2 /Hz at 19.5–250 Hz frequency band, and the starting point of perturbations not exceeding 10 • relative to the epicentral latitude. Among the 69 earthquakes, it is shown that electrostatic perturbations were detected at ULF-ultra low frequency and ELF-extremely low frequency band before the 32 earthquakes, nearly 46 %. Furthermore, we extended the searching scale of these perturbations to the globe, and it can be found that before some earthquakes, the electrostatic anomalies were distributed in a much larger area a few days before, and then they concentrated to the closest orbit when the earthquake would happen one day or a few hours later, which reflects the spatial developing feature during the seismic preparation process. The results in this paper contribute to a better description of the electromagnetic (EM) disturbances at an altitude of 660– 710 km in the ionosphere that can help towards a further understanding of the lithosphere-atmosphere-ionosphere (LAI) coupling mechanism

Evaluating the effectiveness of using personal tailored risk information and taster sessions to increase the uptake of smoking cessation services: study protocol for a randomised controlled trial

Although government-funded specialist smoking cessation services in England offer advice and support to smokers motivated to quit, only a small proportion of smokers make use of this service. Evidence suggests that if smokers are proactively and personally invited to use services, use will be higher than with a standard referral made by health professionals. Computer-based systems generating personalised tailored communications also have the potential to engage with a larger proportion of the smoking population. In this study smokers are proactively invited to use the NHS Stop Smoking Service (SSS), with a personal computer-tailored letter and the offer of a no-commitment introductory session designed to give more information about the service. The primary objective is to assess the relative effectiveness on attendance at the NHS SSS, of proactive recruitment by a brief personal letter, tailored to individual characteristics, and invitation to a taster session, over a standard generic letter advertising the service

Ionospheric disturbances generated by different natural processes and by human activity in Earth plasma environment

The magnetosphere-ionosphere-thermosphere subsystem is strongly coupled via the electric field, particle precipitation, heat flows and small scale interaction. Satellites in situ measurements and ground based complex diagnostics can provide comprehensive coverage of both time and geomagnetic place effects. Human activity also can perturb Earth s environment, but few are connected with controlled experiments in the ionosphere and are transient. Most of them are related to industrial activity and have increased in recent years. The most important power sources are broadcasting transmitters, power stations, power lines and heavy industry. At ionospheric altitude some disturbances and physical processes are related to seismic activity, thunderstorm activity and some global changes in the Earth environment such as ozone holes. Various natural and artificial indicators can affect satellite telecommunication quality. The aim of this presentation is to report progress in understanding the physical processes in the ionosphere described above and to assess the application of these considerations to the study of plasma effects on Earth-space and satellite-to-satellite communication

Atmospheric and ionospheric coupling phenomena related to large earthquakes

This paper explores multi-instrument space-borne observations in order to validate physical concepts of Lithosphere-Atmosphere-Ionosphere Coupling (LAIC) in relation to major seismic events. In this study we apply already validated observation to identify atmospheric and ionospheric precursors associated with some of recent most destructive earthquakes: M8.6 of March 25, 2005 and M8.5 September 15, 2007 in Sumatra, and M7.9 May 12, 2008 in Wenchuan, China. New investigations are also presented concerning these three earthquakes and for the M7.3 March 2008 in the Xinjiang-Xizang border region, China (the Yutian earthquake). It concerns the ionospheric density, the Global Ionospheric Maps (GIM) of the Total Electron Content (TEC), the Thermal Infra-Red (TIR) anomalies, and the Outgoing Longwave Radiation (OLR) data. It is shown that all these anomalies are identified as short-term precursors, which can be explained by the LAIC concept proposed by Pulinets and Ouzounov (2011)

Atmospheric and ionospheric coupling phenomena associated with large earthquakes

This paper explores multi-instrument space-borne observations in order to validate physical concepts of Lithosphere-AtmosphereIonosphere Coupling (LAIC) in relation to a selection of major seismic events. In this study we apply some validated techniques to observations in order to identify atmospheric and ionospheric precursors associated with some of recent most destructive earthquakes: M8.6 of March 28, 2005 and M8.5 of Sept. 12, 2007 in Sumatra, and M7.9 of May 12, 2008 in Wenchuan, China. New investigations are also presented concerning these three earthquakes and for the M7.2 of March 2008 in the Xinjiang-Xizang border region, China (the Yutian earthquake). It concerns the ionospheric density, the Global Ionospheric Maps (GIM) of the Total Electron Content (TEC), the Thermal InfraRed (TIR) anomalies, and the Outgoing Longwave Radiation (OLR) data. It is shown that all these anomalies are identified as short-term precursors, which can be explained by the LAIC concept proposed in [S. Pulinets, D. Ouzounov, J. Asian Earth Sci. 41, 371 (2011)]

Perbedaan Asupan Lemak, Lingkar Pinggang dan Persentase Lemak Tubuh pada Wanita Dislipidemia dan Non Dislipidemia

Differences of fat intake, waist circumference and percentage of bodt fat in dyslipidemia and non dyslipidemia adult women: Heart disease is the leading cause of death in several countries in the world . One of the major risk factors for heart disease is dyslipidemia . Dyslipidemia is a disorder of lipid metabolism characterized by an increase or decrease in plasma lipid fractions . Dyslipidemia has a strong relationship with the occurrence of central obesity . The purpose of this study was to analyze differences in the intake of fat , waist circumference and body fat percentage in dyslipidemia and non dyslipidemia adult women. This research is analytic study with cross sectional approach . The population in this study were adult women who examined their lipid profile in December 2013 in the Clinical Laboratory Cito Indraprasta Semarang . The total sample was 32 people . Independent test analysis of the differences using t-test for variables waist circumference and Mann Whitney test for variable fat intake and body fat percentage to 95 % and a significance level of 5% error. The results showed 17 adult women ( 53.1 % ) and 15 female adult dyslipidemia ( 46.9 % ) non- dyslipidemia. Average intake of fat, waist circumference and percentage body fat in adult women dyslipidemia higher than non dyslipidemia in adult women. Analysis of statistical tests showed difference in fat intake , waist circumference and body fat percentage in women adult dyslipidemia and non dyslipidemia (p value, respectively p = 0.002, p = 0.0001 and p = 0.0001