2,013 research outputs found
The Cratering History of Asteroid (2867) Steins
The cratering history of main belt asteroid (2867) Steins has been
investigated using OSIRIS imagery acquired during the Rosetta flyby that took
place on the 5th of September 2008. For this purpose, we applied current models
describing the formation and evolution of main belt asteroids, that provide the
rate and velocity distributions of impactors. These models coupled with
appropriate crater scaling laws, allow the cratering history to be estimated.
Hence, we derive Steins' cratering retention age, namely the time lapsed since
its formation or global surface reset. We also investigate the influence of
various factors -like bulk structure and crater erasing- on the estimated age,
which spans from a few hundred Myrs to more than 1Gyr, depending on the adopted
scaling law and asteroid physical parameters. Moreover, a marked lack of
craters smaller than about 0.6km has been found and interpreted as a result of
a peculiar evolution of Steins cratering record, possibly related either to the
formation of the 2.1km wide impact crater near the south pole or to YORP
reshaping.Comment: Accepted by Planetary and Space Scienc
Divergent effects of liraglutide, exendin-4, and sitagliptin on beta-cell mass and indicators of pancreatitis in a mouse model of hyperglycaemia
AIMS:Glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase-4 (DPP4) inhibitors improve glucose tolerance by still incompletely understood mechanisms. Each class of antihyperglycemic drugs has also been proposed to increase pancreatitis risk. Here, we compare systematically the effects of two widely-used GLP-1 analogues, liraglutide and exendin-4, and the DPP4 inhibitor, sitagliptin, in the mouse. METHODS:C57BL6 mice were maintained for 131 days on a normal diet (ND) or a diet comprising 60% fat (HFD) before measurements of fasting blood glucose and insulin, and intraperitoneal glucose tolerance. Beta- and alpha- cell volume, and Reg3b immunoreactivity, were measured by immunohistochemical analysis of pancreatic slices. RESULTS:Whereas liraglutide (200 µg/kg) and exendin-4 (10 µg/kg) treatment reduced body weight and/or improved glucose tolerance, sitagliptin (10 mg/kg) was without effect on either parameter. Liraglutide caused a sharp reduction in beta-cell mass in both ND and HFD mice, whereas exendin-4 exerted no effect. By contrast, sitagliptin unmasked an action of high fat diet to increase beta-cell mass. Reg3B positive area was augmented by all three agents in normal chow-fed mice, whilst sitagliptin and exendin-4, but not liraglutide, affected this parameter in HFD animals. Correspondingly sitagliptin, but not the GLP-1 analogues, increased circulating amylase levels in ND and HFD mice. CONCLUSIONS:Liraglutide improves glucose tolerance in the mouse whilst exerting relatively modest effects on pancreatitis risk. Conversely, exendin-4 and sitagliptin, at doses which exert, respectively, minor or no effects on metabolic parameters, lead to signs of pancreatitis
Implications of the Small Spin Changes Measured for Large Jupiter-Family Comet Nuclei
Rotational spin-up due to outgassing of comet nuclei has been identified as a possible mechanism for considerable mass-loss and splitting. We report a search for spin changes for three large Jupiter-family comets (JFCs): 14P/Wolf, 143P/Kowal-Mrkos, and 162P/Siding Spring. None of the three comets has detectable period changes, and we set conservative upper limits of 4.2 (14P), 6.6 (143P) and 25 (162P) minutes per orbit. Comparing these results with all eight other JFCs with measured rotational changes, we deduce that none of the observed large JFCs experiences significant spin changes. This suggests that large comet nuclei are less likely to undergo rotationally-driven splitting, and therefore more likely to survive more perihelion passages than smaller nuclei. We find supporting evidence for this hypothesis in the cumulative size distributions of JFCs and dormant comets, as well as in recent numerical studies of cometary orbital dynamics. We added 143P to the sample of 13 other JFCs with known albedos and phase-function slopes. This sample shows a possible correlation of increasing phase-function slopes for larger geometric albedos. Partly based on findings from recent space missions to JFCs, we hypothesise that this correlation corresponds to an evolutionary trend for JFCs. We propose that newly activated JFCs have larger albedos and steeper phase functions, which gradually decrease due to sublimation-driven erosion. If confirmed, this could be used to analyse surface erosion from ground and to distinguish between dormant comets and asteroids
Transiting Disintegrating Planetary Debris around WD 1145+017
More than a decade after astronomers realized that disrupted planetary
material likely pollutes the surfaces of many white dwarf stars, the discovery
of transiting debris orbiting the white dwarf WD 1145+017 has opened the door
to new explorations of this process. We describe the observational evidence for
transiting planetary material and the current theoretical understanding (and in
some cases lack thereof) of the phenomenon.Comment: Invited review chapter. Accepted March 23, 2017 and published October
7, 2017 in the Handbook of Exoplanets. 15 pages, 10 figure
Photometry of cometary nuclei: Rotation rates, colours and a comparison with Kuiper Belt Objects
We present time-series data on Jupiter Family Comets (JFCs) 17P/Holmes,
47P/Ashbrook-Jackson and 137P/Shoemaker-Levy 2. In addition we also present
results from `snap-shot' observations of comets 43P/Wolf-Harrington,
44P/Reinmuth 2, 103P/Hartley 2 and 104P/Kowal 2 taken during the same run. The
comets were at heliocentric distances of between 3 and 7 AU at this time. We
present measurements of size and activity levels for the snap-shot targets. The
time-series data allow us to constrain rotation periods and shapes, and thus
bulk densities. We also measure colour indices (V-R) and (R-I) and reliable
radii for these comets. We compare all of our findings to date with similar
results for other comets and Kuiper Belt Objects (KBOs). We find that the
rotational properties of nuclei and KBOs are very similar, that there is
evidence for a cut-off in bulk densities at ~ 0.6 g cm^{-3} in both
populations, and the colours of the two populations show similar correlations.
For JFCs there is no observational evidence for the optical colours being
dependant on either position in the orbit or on orbital parameters.Comment: 15 pages, 19 figures, accepted for publication in MNRA
Business experience and start-up size: buying more lottery tickets next time around?
This paper explores the determinants of start-up size by focusing on a cohort of 6247 businesses that started trading in 2004, using a unique dataset on customer records at Barclays Bank. Quantile regressions show that prior business experience is significantly related with start-up size, as are a number of other variables such as age, education and bank account activity. Quantile treatment effects (QTE) estimates show similar results, with the effect of business experience on (log) start-up size being roughly constant across the quantiles. Prior personal business experience leads to an increase in expected start-up size of about 50%. Instrumental variable QTE estimates are even higher, although there are concerns about the validity of the instrument
Observing the variation of asteroid thermal inertia with heliocentric distance
Thermal inertia is a useful property to characterise a planetary surface since it can be used as a qualitative measure of the regolith grain size. It is expected to vary with heliocentric distance because of its dependence on temperature. However, no previous investigation has conclusively observed a change in thermal inertia for any given planetary body. We have addressed this by using NEOWISE data and the Advanced Thermophysical Model to study the thermophysical properties of the near-Earth asteroids (1036) Ganymed, (1580) Betulia, and (276049) 2002 CE26 as they moved around their highly eccentric orbits. We confirm that the thermal inertia values of Ganymed and 2002 CE26 do vary with heliocentric distance, although the degree of variation observed depends on the spectral emissivity assumed in the thermophysical modelling. We also confirm that the thermal inertia of Betulia did not change for three different observations obtained at the same heliocentric distance. Depending on the spectral emissivity, the variations for Ganymed and 2002 CE26 are potentially more extreme than that implied by theoretical models of heat transfer within asteroidal regoliths, which might be explained by asteroids having thermal properties that also vary with depth. Accounting for this variation reduces a previously observed trend of decreasing asteroid thermal inertia with increasing size, and suggests that the surfaces of small and large asteroids could be much more similar than previously thought. Furthermore, this variation can affect Yarkovsky orbital drift predictions by a few tens of per cent
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