Fuentes de conocimiento externo en el sector arqueológico español: Mapeo de la fase emergente en una actividad empresarial

[EN] Recent studies of innovation highlight the importance of external knowledge sourcing. Existing empirical works are based on national surveys and specific industries. The present study contributes to the analysis of strategies for sourcing external knowledge, based on a specific case study and moment in time: the Spanish archaeological sector and its emergence as a new business activity. Our results show that external knowledge sourcing involves diverse mechanisms, agents and two main strategies: cooperation and knowledge acquisition. In an expanding knowledge-based sector emerging in an uncertain context and whose sources of knowledge are scattered, innovation strategy should focus on the search for external knowledge ¿cooperation and acquisition strategies-, rather than on internal sources.[ES] Estudios recientes señalan la importancia de las fuentes externas de conocimiento como estrategia para innovar. La evidencia empírica se fundamenta en encuestas nacionales y en industrias específicas. El presente estudio contribuye al análisis de las estrategias de incorporación de conocimiento externo mediante un caso de estudio y en un momento concreto: el sector arqueológico español y su emergencia como nueva actividad económica. Los resultados muestran que las fuentes de conocimiento externo implican diversos mecanismos, agentes y dos estrategias principalmente: cooperar y adquirir conocimiento. En un sector en expansión, basado en el conocimiento, que surge en un contexto incierto y cuyas fuentes de conocimiento están dispersas, el foco de la innovación puede encontrarse en las estrategias de búsqueda de conocimiento externo -cooperación y adquisición-, más que en fuentes internas.This work was supported by the ACE (Archaeology in Contemporary Europe) Project, funded by the European Commission Cultural Programme between 2008 and 2012. The authors are grateful to the archaeologists and archaeological firms that participated in the study. Special thanks go to the Institute of Heritage Sciences (Incipit-CSIC) and INGENIO (CSIC-UPV) for the support and help. We also thank the anonymous reviewers for their helpful comments. Finally, we appreciate the English text editing by Cynthia Little, a specialist in our area, which always helps us in this activity.Parga-Dans, E.; Castro-Martínez, E.; Sánchez-Barrioluengo, M. (2017). External knowledge sourcing in the Spanish archaeological sector: Mapping the emergent stage of a business activity. Revista española de Documentación Científica. 40(1):1-14. doi:10.3989/redc.2017.1.1380S114401Langvall, O. (2011). Impact of climate change, seedling type and provenance on the risk of damage to Norway spruce (Picea abies (L.) Karst.) seedlings in Sweden due to early summer frosts. Scandinavian Journal of Forest Research, 26(S11), 56-63. doi:10.1080/02827581.2011.564399Nielsen, U. B., Madsen, P., Hansen, J. K., Nord-Larsen, T., & Nielsen, A. T. (2014). Production potential of 36 poplar clones grown at medium length rotation in Denmark. Biomass and Bioenergy, 64, 99-109. doi:10.1016/j.biombioe.2014.03.03

Prevención de Riesgos Psicosociales en época de pandemia

El objetivo de este trabajo es analizar la influencia de los riesgos psicosociales en el nivel de bienestar psicológico de empleados con discapacidad modulada por la autodeterminación y la autoeficacia. Para ello, se analizan 67 trabajadores de una empresa social del sector de la discapacidad, distribuida por Andalucía, Aragón, Asturias y Madrid. Los resultados muestran que las medias de los trabajadores con mayores exigencias cuantitativas, emocionales, y exigencias consideradas de manera global tienen mayores niveles de estrés de forma significativa. Además, los trabajadores con niveles de estrés por encima de la media tienen mayores niveles de conflicto familia-trabajo que los trabajadores con estrés percibido por debajo de la media. Asimismo, la media de las personas con apoyo fue significativamente mayor en los trabajadores con niveles bajos de estrés. También se encontró, que la media de reconocimiento fue más alta en los trabadores con bajos niveles de estrés. No obstante, la autoeficacia y autodeterminación no modularon la relación entre riesgo psicosocial y estrés. <br /

Phytochemical evaluation of white (Morus alba L.) and black (Morus nigra L.) mulberry fruits, a starting point for the assessment of their beneficial properties

Abstract This study evaluated, for the first time, the phenolic content of white ( Morus alba ) and black mulberry ( Morus nigra ) fruits with proven market aptitudes and grown in Spain, one of the main European producers. The antioxidant activity and mineral composition of these promising berry fruits were also assessed. Black mulberry clones showed higher antioxidant activity and amounts of phenolic compounds than white mulberry clones, although a wide intra-species variability was noted, according to principal component analysis. The total anthocyanins varied significantly among clones of M. nigra . These results are keys for the design of future dietary intervention studies examining the role of mulberry fruits in disease risk reduction. They can also be used for the development of mulberry derived-products rich in phenolic compounds

(Poly)phenolic compounds and antioxidant activity of white (Morus alba) and black (Morus nigra) mulberry leaves: Their potential for new products rich in phytochemicals

Abstract The (poly)phenolic fingerprint and antioxidant activities of the leaves of white and black mulberry clones grown in Spain, one of the main European producers, were evaluated for the first time in order to examine their phytochemical potential. Data showed that mulberry leaves are rich in caffeoylquinic acids (6.8–8.5 mg/g dw) and flavonols (3.7–9.8 mg/g dw). It was also evidenced that a wide intra-species variability existed according to principal component analysis. These results can be useful for value-added utilisation of this underused vegetal matrix by the food/pharma industries. In addition, owing to their (poly)phenolic composition with proven biological activities, these data can serve as starting point for further nutritional studies with mulberry leaf-derived products

Bayesian reasoning with emotional material in patients with schizophrenia.

Delusions are one of the most classical symptoms described in schizophrenia. However, despite delusions are often emotionally charged, they have been investigated using tasks involving non-affective material, such as the Beads task. In this study we compared 30 patients with schizophrenia experiencing delusions with 32 matched controls in their pattern of responses to two versions of the Beads task within a Bayesian framework. The two versions of the Beads task consisted of one emotional and one neutral, both with ratios of beads of 60:40 and 80:20, considered, respectively, as the “difficult” and “easy” variants of the task. Results indicate that patients showed a greater deviation from the normative model, especially in the 60:40 ratio, suggesting that more inaccurate probability estimations are more likely to occur under uncertainty conditions. Additionally, both patients and controls showed a greater deviation in the emotional version of the task, providing evidence of a reasoning bias modulated by the content of the stimuli. Finally, a positive correlation between patients’ deviation and delusional symptomatology was found. Impairments in the 60:40 ratio with emotional content was related to the amount of disruption in life caused by delusions. These results contribute to the understanding of how cognitive mechanisms interact with characteristics of the task (i.e., ambiguity and content) in the context of delusional thinking. These findings might be used to inform improved intervention programs in the domain of inferential reasoning.post-print700 K

Influence of anthopometric variables on the mechanical properties of human rib cortical bone

Objective. The mechanical properties of ribs from a large number of post-mortem human subjects (PMHS) were analyzed to search for variation according to age, sex or BMI in the sample. A large sample of specimens from different donors (N = 64) with a very wide range of ages and anthropometric characteristics was tested. Methods. Uniaxial tensile tests were used for a sample of coupons machined from cortical bone tissue in order to isolate the purely mechanical properties from the geometrically influenced properties of the rib. Each coupon is about 25 mm long and has a thickness of about 0.5 mm. The mechanical properties measured for each specimen/coupon include YM, yield stress, ultimate stress (maximum failure stress), ultimate strain, and resilience (energy to fracture of SED). The study provides new methodological improvements in DIC techniques. Results. This study is notable for using an atypically large sample of number of PMHS. The size of the sample allowed the authors to determine that age has a significant effect on failure stress (p < 0.0001), yield stress (p = 0.0047), ultimate strain (p < 0.0001) and resilience (p < 0.0001) [numbers in parentheses represent the corresponding p - values]. Finally, there is a combined effect, so that for a given age, an increase of BMI leads to a decrease of the maximum strain (i.e. cortical bone is less stiff when both age and BMI are higher).Peer ReviewedPostprint (author's final draft

Sleep quality among inpatients of Spanish public hospitals

Sleep is a complex process and is needed both in health and illness. Deprivation of sleep is known to have multiple negative physiological effects on people's bodies and minds. Despite the awareness of these harmful effects, previous studies have shown that sleep is poor among hospitalised patients. We utilized an observational design with 343 patients recruited from medical and surgical units in 12 hospitals located in nine Spanish regions. Sociodemographic and clinical characteristics of patients were collected. Sleep quality at admission and during hospitalisation was measured by the Pittsburgh Sleep Quality Index. Sleep quantity was self-reported by patients in hours and minutes. Mean PSQI score before and during hospitalisation were respectively 8.62 ± 4.49 and 11.31 ± 4.04. Also, inpatients slept about an hour less during their hospital stay. Lower educational level, sedative medication intake, and multi-morbidity was shown to be associated with poorer sleep quality during hospitalisation. A higher level of habitual physical activity has shown to correlate positively with sleep quality in hospital. Our study showed poor sleep quality and quantity of inpatients and a drastic deterioration of sleep in hospital versus at home. These results may be helpful in drawing attention to patients' sleep in hospitals and encouraging interventions to improve sleep.This project received a research grant from the Carlos III Institute of Health, Ministry of Economy and Competitiveness (Spain), awarded on the 2018 call under the Health Strategy Action 2013–2016, with reference PI18/00732, PI18/00743, PI18CIII/0012, co-funded with the European Union ERDF funds (European Reginal Development Fund “a way to make Europe) and the Predoctoral staff in training program from the University of Lleida, Jade Plus and La Caixa Bank Foundation 2019.S

Tin perovskite solar cells with >1,300 h of operational stability in N2 through a synergistic chemical engineering approach

Despite the promising properties of tin-based halide perovskites, one clear limitation is the fast Sn+2 oxidation. Consequently, the preparation of long-lasting devices remains challenging. Here, we report a chemical engineering approach, based on adding Dipropylammonium iodide (DipI) together with a well-known reducing agent, sodium borohydride (NaBH4), aimed at preventing the premature degradation of Sn-HPs. This strategy allows for obtaining efficiencies (PCE) above 10% with enhanced stability. The initial PCE remained unchanged upon 5 h in air (60% RH) at maximum-power-point (MPP). Remarkably, 96% of the initial PCE was kept after 1,300 h at MPP in N2. To the best of our knowledge, these are the highest reported values for Sn-based solar cells. Our findings demonstrate a beneficial synergistic effect when additives are incorporated, highlight the important role of iodide in the performance upon light soaking, and, ultimately, unveil the relevance of controlling the halide chemistry for future improvement of Sn-based perovskite devices

Azure A embedded in carbon dots as NADH electrocatalyst: Development of a glutamate electrochemical biosensor

Carbon nanodots modified with azure A (AA-CDs) have been synthesized and applied as redox mediator of bioelectrocatalytic reactions. A deep characterization of AA-CDs nanomaterial has been carried out, proving the covalent attachment of azure A molecules into the carbon dots nanostructure. Disposable screen-printed carbon electrodes (SPCE) have been modified with AA-CDs, through the action of chitosan polymer (Chit-AA-CDs/SPCE). The Chit-AA-CDs/SPCE electrocatalytic activity towards the oxidation of NADH has been proved, obtaining excellent results regarding the low oxidation potential achieved (−0.15 V vs. Ag) and low detection and quantification limits (LOD and LOQ) for NADH, 16 and 53 µM, respectively. The developed electrochemical platform has been applied for the construction of a glutamate biosensor by immobilizing L-glutamic dehydrogenase (GLDH/Chit-AA-CDs/SPCE). The morphology of GLDH/Chit-AA-CDs/SPCE platform was analysed by AFM at each different step of the electrode modification process. The resulting biosensing platform is capable of detect NADH enzymatically generated by GLDH in the presence of glutamate and NAD+. Good analytical parameters were obtained for glutamate analysis using GLDH/Chit-AA-CDs/SPCE, as LOD and LOQ of 3.3 and 11 µM, respectively. The biosensor has been successfully applied to the analysis of food and biological samplesThis work has been supported by the Spanish Ministerio de Ciencia e Innovacion (PID2020–116728RB-I00) and Comunidad Autonoma de Madrid (SI3/PJI/2021–00341, P2018/NMT-4349 TRANSNANOAVANSENS Program

Alteration of cell wall xylan acetylation triggers defense responses that counterbalance the immune deficiencies of plants impaired in the β‐subunit of the heterotrimeric G‐protein

[EN] Arabidopsis heterotrimeric G-protein complex modulates pathogen-associated molecular pattern-triggeredimmunity (PTI) and disease resistance responses to different types of pathogens. It also plays a role in plantcell wall integrity as mutants impaired in the Gb-(agb1-2)orGc-subunits have an altered wall compositioncompared with wild-type plants. Here we performed a mutant screen to identify suppressors ofagb1-2(sgb) that restore susceptibility to pathogens to wild-type levels. Out of the foursgbmutants (sgb10–sgb13)identified,sgb11is a new mutant allele ofESKIMO1(ESK1), which encodes a plant-specific polysaccharideO-acetyltransferase involved in xylan acetylation. Null alleles (sgb11/esk1-7)ofESK1restore to wild-typelevels the enhanced susceptibility ofagb1-2to the necrotrophic fungusPlectosphaerella cucumerina BMM(PcBMM), but not to the bacteriumPseudomonas syringaepv.tomatoDC3000 or to the oomyceteHyaloper-onospora arabidopsidis. The enhanced resistance toPcBMMof theagb1-2 esk1-7double mutant was notthe result of the re-activation of deficient PTI responses inagb1-2. Alteration of cell wall xylan acetylationcaused byESK1impairment was accompanied by an enhanced accumulation of abscisic acid, the constitu-tive expression of genes encoding antibiotic peptides and enzymes involved in the biosynthesis of trypto-phan-derived metabolites, and the accumulation of disease resistance-related secondary metabolites anddifferent osmolites. Theseesk1-mediated responses counterbalance the defective PTI andPcBMMsuscepti-bility ofagb1-2plants, and explain the enhanced drought resistance ofesk1plants. These results suggestthat a deficient PTI-mediated resistance is partially compensated by the activation of specific cell-wall-trig-gered immune responses.SISpanish Ministry of Economy and Competitiveness (MINECO) grants BIO2012-32910 to A.M.The Australian Research Council Centre of Excellence in Plant Cell Walls and matching funding from KTH (grants to V.B) and NIGMS (R01GM065989) and NSF (MCB-1713880) to A.M.J. The Division of Chemical Sciences, Geosciences, and Biosciences, Office of Basic Energy Sciences of the US Department of Energy through the grant DE-FG02-05er15671 to A.M.J. funded technical support in this study. H.M. was supported by an IEF grant (SignWALLINg-624721) from the European Union, E.M. by a Juan de la Cierva Postdoctoral Fellow from MINECO, S.S. by the BRAVE Erasmus Mundi Program (European Union), and A.M.-B. was the recipient of a PIF fellow from Universidad Politécnica de Madrid