Understanding the Cultural-Linguistic Divide in American Classrooms: Language Learning Strategies for a Diverse Student Population

This article addresses critical factors that impact learning for a growing population of students in American classrooms, the English Language Learner (ELL). Even in the smallest school districts, it is common for teachers to have one or more students with limited or no command of the English language in their classrooms. Many students in schools with specialized ELL programs spend the majority of their day in regular classrooms trying to fit in with their peers as they struggle to learn a new language. This article focuses on the five stages of language acquisition and proficiency along with corresponding research-based strategies teachers can use at each stage. Elements of an effective language program described in this article are based on an asset model of instruction where students’ differences are valued, respected, and utilized. When cultural-linguistic differences are used as assets rather than problems, all students, native and non-native English speakers, benefit

Survivors of Aortic Dissection: Activity, Mental Health, and Sexual Function

BackgroundCurrently no research exists assessing lifestyle modifications and emotional state of acute aortic dissection (AAD) survivors. We sought to assess activity, mental health, and sexual function in AAD survivors.HypothesisPhysical and sexual activity will decrease in AAD survivors compared to pre‐dissection. Incidence of anxiety and depression will be significant after AAD.MethodsA cross sectional survey was mailed to 197 subjects from a single academic medical center (part of larger IRAD database). Subjects were ≥18 years of age surviving a type A or B AAD between 1996 and 2011. 82 surveys were returned (overall response rate 42%).ResultsMean age ± SD was 59.5 ± 13.7 years, with 54.9% type A and 43.9% type B patients. Walking remained the most prevalent form of physical activity (49 (60%) pre‐dissection and 47 (57%) post‐dissection). Physical inactivity increased from 14 (17%) before AAD to 20 (24%) after AAD; sexual activity decreased from 31 (38%) to 9 (11%) mostly due to fear. Most patients (66.7%) were not exerting themselves physically or emotionally at AAD onset. Systolic blood pressure (SBP) at 36 months post‐discharge for patients engaging in ≥2 sessions of aerobic activity/week was 126.67 ± 10.30 vs. 141.10 ± 11.87 (p‐value 0.012) in those who did not. Self‐reported new‐onset depression after AAD was 32% and also 32% for new‐onset anxiety.ConclusionsAlterations in lifestyle and emotional state are frequent in AAD survivors. Clinicians should screen for unfounded fears or beliefs after dissection that may reduce function and/or quality of life for AAD survivors.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/116073/1/clc22418_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/116073/2/clc22418.pd

Halo globular clusters observed with AAOmega: dark matter content, metallicity and tidal heating

Globular clusters have proven to be essential to our understanding of many important astrophysical phenomena. Here we analyse spectroscopic observations of ten Halo globular clusters to determine their dark matter content, their tidal heating by the Galactic disc and halo, describe their metallicities and the likelihood that Newtonian dynamics explain their kinematics. We analyse a large number of members in all clusters, allowing us to address all these issues together, and we have included NGC 288 and M30 to overlap with previous studies. We find that any flattening of the velocity dispersion profiles in the outer regions of our clusters can be explained by tidal heating. We also find that all our GCs have M/L_V < 5, therefore, we infer the observed dynamics do not require dark matter, or a modification of gravity. We suggest that the lack of tidal heating signatures in distant clusters indicates the Halo is not triaxial. The isothermal rotations of each cluster are measured, with M4 and NGC 288 exhibiting rotation at a level of 0.9 +/- 0.1 km/s and 0.25 +/- 0.15 km/s, respectively. We also indirectly measure the tidal radius of NGC 6752, determining a more realistic figure for this cluster than current literature values. Lastly, an unresolved and intriguing puzzle is uncovered with regard to the cooling of the outer regions of all ten clusters.Comment: 12 pages, 8 figures, 1 table. Accepted for publication in MNRAS

Radial Velocity and Metallicity of the Globular Cluster IC4499 Obtained with AAOmega

We present radial velocity and metallicity measurements for the far-southern Galactic globular cluster IC4499. We selected several hundred target red giant stars in and around the cluster from the 2MASS point source catalog, and obtained spectra at the near-infrared calcium triplet using the AAOmega spectrograph. Observations of giants in globular clusters M4, M22, and M68 were taken to provide radial velocity and metallicity comparison objects. Based on velocity data we conclude that 43 of our targets are cluster members, by far the largest sample of IC4499 giants spectroscopically studied. We determine the mean heliocentric radial velocity of the cluster to be 31.5 plus or minus 0.4 km/s, and find the most likely central velocity dispersion to be 2.5 plus or minus 0.5 km/s. This leads to a dynamical mass estimate for the cluster of 93 plus or minus 37 thousand solar masses. We are sensitive to cluster rotation down to an amplitude of about 1 km/s, but no evidence for cluster rotation is seen. The cluster metallicity is found to be [Fe/H] = -1.52 plus or minus 0.12 on the Carretta-Gratton scale. The radial velocity of the cluster, previously highly uncertain, is consistent with membership in the Monoceros tidal stream, but also with a halo origin. The horizontal branch morphology of the cluster is slightly redder than average for its metallicity, but it is likely not unusually young compared to other clusters of the halo. The new constraints on the cluster kinematics and metallicity may give insight into its extremely high specific frequency of RR Lyrae stars.Comment: Accepted to MNRAS, 13 pages, 9 figure

Limited Liability Companies in Kentucky: Applications & New Topics for the LLC

Materials from the Limited Liability Companies in Kentucky conference held by UK/CLE in October 1999

Specific MRI abnormalities reveal severe perrault syndrome due to CLPP defects

In establishing a genetic diagnosis in heterogeneous neurological disease, clinical characterization and whole exome sequencing (WES) go hand-in-hand. Clinical data are essential, not only to guide WES variant selection and define the clinical severity of a genetic defect but also to identify other patients with defects in the same gene. In an infant patient with sensorineural hearing loss, psychomotor retardation, and epilepsy, WES resulted in identification of a novel homozygous CLPP frameshift mutation (c.21delA). Based on the gene defect and clinical symptoms, the diagnosis Perrault syndrome type 3 (PRLTS3) was established. The patient's brain-MRI revealed specific abnormalities of the subcortical and deep cerebral white matter and the middle blade of the corpus callosum, which was used to identify similar patients in the Amsterdam brain-MRI database, containing over 3000 unclassified leukoencephalopathy cases. In three unrelated patients with similar MRI abnormalities the CLPP gene was sequenced, and in two of them novel missense mutations were identified together with a large deletion that covered part of the CLPP gene on the other allele. The severe neurological and MRI abnormalities in these young patients were due to the drastic impact of the CLPP mutations, correlating with the variation in clinical manifestations among previously reported patients. Our data show that similarity in brain-MRI patterns can be used to identify novel PRLTS3 patients, especially during early disease stages, when only part of the disease manifestations are present. This seems especially applicable to the severely affected cases in which CLPP function is drastically affected and MRI abnormalities are pronounced

Specific MRI Abnormalities Reveal Severe Perrault Syndrome due to CLPP Defects

In establishing a genetic diagnosis in heterogeneous neurological disease, clinical characterization and whole exome sequencing (WES) go hand-in-hand. Clinical data are essential, not only to guide WES variant selection and define the clinical severity of a genetic defect but also to identify other patients with defects in the same gene. In an infant patient with sensorineural hearing loss, psychomotor retardation, and epilepsy, WES resulted in identification of a novel homozygous CLPP frameshift mutation (c.21delA). Based on the gene defect and clinical symptoms, the diagnosis Perrault syndrome type 3 (PRLTS3) was established. The patient's brain-MRI revealed specific abnormalities of the subcortical and deep cerebral white matter and the middle blade of the corpus callosum, which was used to identify similar patients in the Amsterdam brain-MRI database, containing over 3000 unclassified leukoencephalopathy cases. In three unrelated patients with similar MRI abnormalities the CLPP gene was sequenced, and in two of them novel missense mutations were identified together with a large deletion that covered part of the CLPP gene on the other allele. The severe neurological and MRI abnormalities in these young patients were due to the drastic impact of the CLPP mutations, correlating with the variation in clinical manifestations among previously reported patients. Our data show that similarity in brain-MRI patterns can be used to identify novel PRLTS3 patients, especially during early disease stages, when only part of the disease manifestations are present. This seems especially applicable to the severely affected cases in which CLPP function is drastically affected and MRI abnormalities are pronounce

Companions of old brown dwarfs, and very low mass stars

Up to now, most planet search projects have concentrated on F to K stars. In order to considerably widen the view, we have stated a survey for planets of old, nearby brown dwarfs and very low mass stars. Using UVES, we have observed 26 brown dwarfs and very low mass stars. These objects are quite inactive and are thus highly suitable for such a project. Two objects were found to be spectroscopic binaries. Another object shows significant radial velocity variations. From our measurements, we conclude that this object either has a planetary-mass companion, or the variations are caused by surface features. Within the errors of the measurements, the remaining objects are constant in radial velocity. While it is impossible to strictly exclude an orbiting planet from sparsely sampled RV data, we conclude that it is unlikely that these objects are orbited by massive planets with periods of 40 days or less.Comment: 7 pages (Latex), 2 figures. accepted for publication in Astronomy & Astrophysic

Women, but not men, have prolonged QT interval if depressed after an acute coronary syndrome

Aims Depression is a mortality risk marker for acute coronary syndrome (ACS) patients. We hypothesized that the QT interval, a predictor for risk of sudden cardiac death, was related to depressive symptoms in ACS. Methods and results We performed an analysis of admission electrocardiograms from hospitalized patients with unstable angina or non-ST elevation myocardial infarction from two prospective observational studies of depression in ACS. Depressive symptoms were assessed with the Beck Depression Inventory (BDI), and depression was defined as BDI score ≥10, compared with <5. Patients with QRS duration ≥120 ms and/or who were prescribed antidepressants were excluded. QT intervals were adjusted for heart rate by two methods. Our analyses included 243 men (40.0% with BDI ≥10) and 139 women (62.0% with BDI ≥ 10). Among women, average QT corrected by Fridericia's method (QTcF) was 435.4 ± 26.6 ms in the depressed group, vs. 408.6 ± 24.3 ms in the non-depressed group (P< 0.01). However, among men, average QTcF was not significantly different between the depressed and non-depressed groups (415.4 ± 23.6 vs. 412.0 ± 25.8 ms, P= 0.29). In multivariable analyses that included hypertension, diabetes, ACS type, left ventricular ejection fraction <0.40, and use of QT-prolonging medication, there was a statistically significant interaction between depressive symptoms and gender (P< 0.001). Conclusions In this ACS sample, prolongation of the QT interval was associated with depressive symptoms in women, but not in men. Further investigation of the mechanism of the relationship between depression and abnormal cardiac repolarization, particularly in women, is warranted to develop treatment strategies

Low-resolution spectroscopy of main sequence stars belonging to 12 Galactic globular clusters. I. CH and CN band strength variations

Globular clusters show abundance variations for light elements that are not yet well understood. The preferred explanation involves a self-enrichment scenario, with two subsequent generations of stars. Observations of main sequence stars allow us to investigate the signature of this chemically processed material without the complicating effects of internal mixing. Our goal is to investigate the C-N anti-correlation with low-resolution spectroscopy of 20-50 stars fainter than the first dredge-up in seven globular clusters (NGC288, NGC1851, NGC5927, NGC6352, NGC6388, and Pal12) with different properties. We complemented our observations with 47~Tuc archival data, with four additional clusters from the literature (M15, M22, M55, NGC362), and with additional literature data on NGC288. In this first paper, we measured the strength of CN and CH band indices, and we investigated the anti-correlation and bimodality of these indices. We compared r_CN, the ratio of stars belonging to the CN-strong and weak groups, with 15 different cluster parameters. We clearly see bimodal anti-correlation of the CH and CN band stregths in the metal-rich clusters (Pal12, 47Tuc, NGC6352, NGC5927). Only M15 among the metal-poor clusters shows a clearly bimodal anti-correlation. We found weak correlations (sligthly above 1 sigma) of r_CN with the cluster orbital parameters, present-day total mass, cluster concentration, and age. Our findings support the self-enrichment scenario, and suggest that the occurrence of more than two major generations of stars in a GGC should be rare. Small additional generations (<10-20% of the total) would be difficult to detect with our samples. The first generation, which corresponds to the CN-weak stars, usually contains more stars than the second one (=0.82+/-0.29), as opposed to results based on the Na-O anti-correlations.Comment: 18 pages, 10 figures, 1 electronic table, accepted for publication in A&A (language edited version