15 research outputs found
<span style="font-size:10.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-US">Flavones and triterpenes from the leaves of <i style="mso-bidi-font-style: normal">Vitex peduncularis</i></span>
279-282A new flavone,
4'-acetoxy-5-hydroxy-6,7-dimethoxyflavone 1
together with four known compounds, cirsimaritin <b style="mso-bidi-font-weight:
normal">2, genkwanin 3, 3α-friedelinol <b style="mso-bidi-font-weight:
normal">4 and 3β-friedelinol
5 have been isolated from the leaves
of Vitex peduncularis Wall.
(Verbenaceae). The structure of the new flavone was elucidated by detailed
spectral (including 2D-NMR) and chemical studies.
</span
γ-Carboline AC190 analogues via palladium catalysed allene insertion stereo and regioselective 3- and 5- component cascades
γ-Carbolines were prepared from pyrido[4,3-b]-5H-indoles via Pd(0)-catalysed, stereo and regioselective allene/uridine allene insertion 3- and 5- component cascades. This versatile reaction sequence gives a range of structurally diverse carboline derivatives and tolerates a broad range of substrates. The power of this approach has been harnessed to produce γ-carboline based HDAC inhibitors