15 research outputs found

    <span style="font-size:10.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-US">Flavones and triterpenes from the leaves of <i style="mso-bidi-font-style: normal">Vitex peduncularis</i></span>

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    279-282A new flavone, 4'-acetoxy-5-hydroxy-6,7-dimethoxyflavone 1 together with four known compounds, cirsimaritin <b style="mso-bidi-font-weight: normal">2, genkwanin 3, 3α-friedelinol <b style="mso-bidi-font-weight: normal">4 and 3β-friedelinol 5 have been isolated from the leaves of Vitex peduncularis Wall. (Verbenaceae). The structure of the new flavone was elucidated by detailed spectral (including 2D-NMR) and chemical studies. </span

    γ-Carboline AC190 analogues via palladium catalysed allene insertion stereo and regioselective 3- and 5- component cascades

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    γ-Carbolines were prepared from pyrido[4,3-b]-5H-indoles via Pd(0)-catalysed, stereo and regioselective allene/uridine allene insertion 3- and 5- component cascades. This versatile reaction sequence gives a range of structurally diverse carboline derivatives and tolerates a broad range of substrates. The power of this approach has been harnessed to produce γ-carboline based HDAC inhibitors
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