Objetos Virtuales de Aprendizaje y su contribución a las competencias matemáticas de los estudiantes de tercer grado

Maestría en Educación - Modalidad VirtualOne of the areas with the highest academic mortality in the educational institutions of San Andre is mathematics. Considering this problem, this article aims to show what has been the contribution of virtual learning objects in the teaching of mathematics to students of the educational institutions Brooks Hill Bilingual School and Flowers Hill Bilingual School of San Andres, Islands. The study is structured as follows: description of the research problem, theoretical and conceptual review through a framework of reference, the methodological aspects and the presentation, interpretation and analysis of the results. It is concluded that the pedagogical accompaniment with the use of virtual learning objects, for the acquisition of mathematics for third grade students, is an effective educational strategy, which favors the acquisition of mathematical concepts in students, improving interest in the subject and favoring the conditions for their learningUna de las áreas que presenta mayor mortalidad académica en las instituciones educativas en San Andrés, es la de matemáticas. Considerando esta problemática, el presente artículo, pretende mostrar cual ha sido la contribución de los objetos virtuales de aprendizaje (OVA) en la enseñanza de las matemáticas, a estudiantes de las Instituciones Educativas Brooks Hill Bilingual School y Flowers Hill Bilingual School de San Andrés, Islas. El estudio, se encuentra estructurado así: descripción del problema de investigación, revisión teórica y conceptual a través de un marco referencia, los aspectos metodológicos y la presentación, interpretación y análisis de resultados. Se concluye que el acompañamiento pedagógico con la utilización del OVA, para la enseñanza de la matemática en los estudiantes de 3 grado, es una estrategia educativa eficaz, que favorece la adquisición de los conceptos matemáticos en los alumnos, mejorando el interés por la materia y favoreciendo las condiciones para su aprendizaje

Acompañamiento pedagógico en el logro de aprendizaje de la evaluación censal en los estudiantes de las Instituciones Educativas Públicas del distrito de Salas - Ica

La tesis Acompañamiento pedagógico en el logro de los aprendizajes de la Evaluación Censal en los estudiantes de las instituciones educativas públicas del distrito de Salas – Ica demuestra cómo las estrategias pedagógicas concretas, las prácticas continuas y el trabajo colaborativo de los docentes logra resultados favorables en la lectura y la matemática en los estudiantes. El trabajo es una investigación no experimental de diseño transaccional correlacional, con una muestra no probabilística de 6 docentes y 174 estudiantes del segundo grado de primaria. Como instrumento se utilizó la lista de cotejo, la ficha de autoevaluación docente y el registro de Evaluación Censal. Como resultado de ambas variables tienen una correlación buena según el coeficiente de Rho Spearman de 0,719.Universidad Nacional de Educación Enrique Guzmán y Valle.Tesi

Aportes a la formación docente desde comunidades de aprendizaje

Advertimos que los procesos de prácticas en los profesorados parecieran conservar una tendencia en los modos y formas de desarrollar las mismas, sostenidas en una perspectiva aplicacionista y hetero-formativa. Por nuestra parte, sostenemos que las prácticas suelen constituirse en un territorio propicio para que los estudiantes de formación docente desplieguen una mirada crítica y reflexiva sobre las actuaciones y decisiones a desempeñar, fortaleciendo la autoformación y emancipación. Con ese propósito desarrollamos una  experiencia compartida en el marco de la propuesta de Comunidades de Aprendizaje y prácticas de estudiantes del Profesorado de Educación Primaria del IES N°6001 y del Profesorado en Ciencias de la Educación de la Universidad de la Nacional de Salta, cuyos aprendizajes iniciales aquí presentamos. Se trata de una experiencia formativa que propicia que los estudiantes se desempeñen en las fases de transformación que vive una escuela, asumiendo distintos desempeños en el marco del proyecto mencionado. Comunidades de Aprendizaje es propuesto por el CREA (Centro de Teorías y Prácticas Superadoras de las Desigualdades, de la Universidad de Barcelona). Sus principios fundamentan la necesidad de la transformación social y cultural de una escuela y su entorno para responder de forma igualitaria a los retos y necesidades que plantea la sociedad actual.

Reconceptualizing zoos through Mille-Oeille : A posthuman techno-architecture to sustain a human/non-human/culture continuum

Technological mediation expands and multiplies our bodily capacities, since it influences the way we relate to our environment. This directly affects our notion of architecture, its scope and practice. From the body-machine to super-bodies and enhanced senses, to the virtual, or the de-codification of data into visual and physical experience, we nowadays require new ethical arguments and considered awareness. This architectural proposal presents a sensitive use of technology that supports and encourages environmental and social sustainability. Supported by scientific literature, it anticipates a novel use of augmented reality and proposes future architectural scenarios which include new materializations and forms of spatial and sensorial experiences.acceptedVersionPeer reviewe

Systematic Analysis of Transrectal Prostate Biopsies Using an Ink Method and Specific Histopathologic Protocol: A Prospective Study

Background. Transrectal prostate biopsy is the standard protocol for the screening for prostate cancer. It helps to locate prostatic adenocarcinoma and plan treatment. However, the increasing number of prostate biopsies leads to considerably greater costs for the pathology laboratories. In this study, we compare the traditional method with an ink method in combination with a systematic histopathologic protocol. Methods. Two hundred consecutive transrectal prostate biopsy specimens were received from the radiology department. They were separated into two groups: one hundred were processed as six different specimens in the usual manner. The other one hundred were submitted in six containers, the apex, base, and middle section of which were stained different colours. The samples subject to the ink method were embedded in paraffin and placed in two cassettes which were sectioned using a specific protocol. Results. The comparative study of the nonink and ink methods for histopathologic diagnosis showed no statistical differences as far as diagnostic categories were concerned (P  value < .005). The number of PIN diagnoses increased when the ink method was used, but no statistical differences were found. The ink method led to a cost reduction of 48.86%. Conclusions. Our ink method combined with a specific histopathologic protocol provided the same diagnostic quality, tumor location information as the traditional method, and lower pathology expenses

Modeling Pathogenic Mutations of Human Twinkle in Drosophila Suggests an Apoptosis Role in Response to Mitochondrial Defects

The human gene C10orf2 encodes the mitochondrial replicative DNA helicase Twinkle, mutations of which are responsible for a significant fraction of cases of autosomal dominant progressive external ophthalmoplegia (adPEO), a human mitochondrial disease caused by defects in intergenomic communication. We report the analysis of orthologous mutations in the Drosophila melanogaster mitochondrial DNA (mtDNA) helicase gene, d-mtDNA helicase. Increased expression of wild type d-mtDNA helicase using the UAS-GAL4 system leads to an increase in mtDNA copy number throughout adult life without any noteworthy phenotype, whereas overexpression of d-mtDNA helicase containing the K388A mutation in the helicase active site results in a severe depletion of mtDNA and a lethal phenotype. Overexpression of two d-mtDNA helicase variants equivalent to two human adPEO mutations shows differential effects. The A442P mutation exhibits a dominant negative effect similar to that of the active site mutant. In contrast, overexpression of d-mtDNA helicase containing the W441C mutation results in a slight decrease in mtDNA copy number during the third instar larval stage, and a moderate decrease in life span in the adult population. Overexpression of d-mtDNA helicase containing either the K388A or A442P mutations causes a mitochondrial oxidative phosphorylation (OXPHOS) defect that significantly reduces cell proliferation. The mitochondrial impairment caused by these mutations promotes apoptosis, arguing that mitochondria regulate programmed cell death in Drosophila. Our study of d-mtDNA helicase overexpression provides a tractable Drosophila model for understanding the cellular and molecular effects of human adPEO mutations

P38 MAPK expression and activation predicts failure of response to CHOP in patients with Diffuse Large B-Cell Lymphoma

The p38 MAPK is constitutively activated in B-NHL cell lines and regulates chemoresistance. Accordingly, we hypothesized that activated p38 MAPK may be associated with the in vivo unresponsiveness to chemotherapy in B-NHL patients.Tissue microarrays generated from eighty untreated patients with Diffused Large B Cell Lymphoma (DLBCL) were examined by immunohistochemistry for the expression of p38 and phospho p38 (p-p38) MAPK. In addition, both Bcl-2 and NF-κB expressions were determined. Kaplan Meier analysis was assessed.Tumor tissues expressed p38 MAPK (82 %) and p-p38 MAPK (30 %). Both p38 and p-p38 MAPK expressions correlated with the high score performance status. A significant correlation was found between the expression p-p38 and poor response to CHOP. The five year median follow-up FFS was 81 % for p38(-) and 34 % for p38(+) and for OS was 83 % for p38(-) and 47 % for p38(+). The p-p38(+) tissues expressed Bcl-2 and 90 % of p-p38(-) where Bcl-2(-). The coexpression of p-p38 and Bcl-2 correlated with pool EFS and OS. There was no correlation between the expression of p-p38 and the expression of NF-κB.The findings revealed, for the first time, that a subset of patients with DLBCL and whose tumors expressed high p-p38 MAPK responded poorly to CHOP therapy and had poor EFS and OS. The expression of p38, p-p38, Bcl2 and the ABC subtype are significant risk factors both p38 and p-p38 expressions remain independent prognostic factors