BIRDS AND SUSTAINABLE MANAGEMENT IN MEDITERRANEAN RIPARIAN AREAS: Bird studies in the RIPIDURABLE project

RIPIDURABLE is an INTERREG IIIC European Program involving 10 partners from Portugal, Spain, France and Greece. Scientists, technicians and local/regional authorities worked together to integrate knowledge, knowhow and practice, towards a rational conservation management of riparian zones. Birds can be used to characterize ecosystems, to monitor environmental changes or to assess results of restoration measures. We have conducted field surveys in order to assess breeding bird communities associated to riparian galleries in several watercourses, including issues as the relation with natural vegetation profiles, the influence of the surrounding matrix, the evolution with time or with habitat degradation, the effects of rehabilitation measures, and/or the importance of riparian galleries as ecological corridors for birds. Surveys at different space and time scales were carried out using standardised point count methods, on 8 watercourses in Portugal and France. We focused on different aspects of riparian breeding bird community variation: along a decreasing gradient of vegetal complexity (Tagus Basin), along an upstream-downstream gradient (Allier), with different surrounding landscapes (Sado, Guadiana and Tagus Basin), with time (Alcáçovas at a 10 years interval, Allier at 16 years interval), with management status (Vidourle), with time & management status (Rhône delta at a 12 years intervals), before & after river rehabilitation (Gandum). In addition we studied the dispersal of Barn Owls from upper Tagus Estuary along riparian corridors (TytoTagus Project), and also the importance of riparian habitats of the Guadiana basin on the autumn migration of trans-Saharan birds across the Iberian Peninsula. The RIPIDURABLE project offered the opportunity for further research currently included in national programs such as the Plan Loire Grandeur Nature which allows long term studies on riparian birds. Herein we briefly present some of the preliminary results of the bird studies carried out by partners from Portugal and France

Las fake news y la actitud de los usuarios del fanpage “Chiclayo al minuto”, 2021

La investigación se realizó con el objetivo de determinar la relación que existe entre las fake news y la actitud de los usuarios de la fanpage “Chiclayo al Minuto”, 2021. El estudio fue de tipo básica, de enfoque cuantitativo, diseño no experimental, descriptivo correlacional: la muestra fue probabilística de 383 usuarios de la fanpage “Chiclayo al Minuto” que interactúan en este medio, aplicándoseles dos cuestionarios para recolección de datos. Los instrumentos fueron validados por juicio de expertos y sometidos a una confiablidad con alfa de Cronbach resultando 0,871 y 0,830. Indicando una buena confiabilidad. Los resultados descriptivos determinaron que existe una asociación directa entre las variables de estudio demostrado por el estadístico chi cuadrado = 135,110 y p valor =0,000, es así que si la variable fake news tiende a ser regularmente perjudicial entonces la actitud de los usuarios es medianamente positiva, afectándolo de alguna manera, esto viene representado por el 43,3% que considera que la variable fake news es Regularmente perjudicial y por ello viene repercutiendo en la forma de Actitud Medianamente positiva. Se comprobó que existe una relación directa y significativa (p=0,000<0,05) entre las variables de estudio, cuyo coeficiente de correlación de spearman de rs= 0,659, determinando una relación significativa positiva alta; por ello, rechazamos la hipótesis nula (H0 de no relación) y aceptamos la alterna (H1) concluyendo que: Las fake news se relacionan directa y significativamente con la actitud de los usuarios de la fanpage “Chiclayo al Minuto”, 2021.TesisComunicación y desarrollo human

Deep Submarine Giant Scours in northern Gulf of Cadiz (offshore SW Iberia) : a singular case of sedimentary and tectonic coupling

European Geosciences Union General Assembly 2007 (EGU 2007), Vienna, Austria, 15-20 April 200

More rapid blood interferon α2 decline in fatal versus surviving COVID-19 patients

BackgroundThe clinical outcome of COVID-19 pneumonia is highly variable. Few biological predictive factors have been identified. Genetic and immunological studies suggest that type 1 interferons (IFN) are essential to control SARS-CoV-2 infection.ObjectiveTo study the link between change in blood IFN-α2 level and plasma SARS-Cov2 viral load over time and subsequent death in patients with severe and critical COVID-19.MethodsOne hundred and forty patients from the CORIMUNO-19 cohort hospitalized with severe or critical COVID-19 pneumonia, all requiring oxygen or ventilation, were prospectively studied. Blood IFN-α2 was evaluated using the Single Molecule Array technology. Anti-IFN-α2 auto-Abs were determined with a reporter luciferase activity. Plasma SARS-Cov2 viral load was measured using droplet digital PCR targeting the Nucleocapsid gene of the SARS-CoV-2 positive-strand RNA genome.ResultsAlthough the percentage of plasmacytoid dendritic cells was low, the blood IFN-α2 level was higher in patients than in healthy controls and was correlated to SARS-CoV-2 plasma viral load at entry. Neutralizing anti-IFN-α2 auto-antibodies were detected in 5% of patients, associated with a lower baseline level of blood IFN-α2. A longitudinal analysis found that a more rapid decline of blood IFN-α2 was observed in fatal versus surviving patients: mortality HR=3.15 (95% CI 1.14–8.66) in rapid versus slow decliners. Likewise, a high level of plasma SARS-CoV-2 RNA was associated with death risk in patients with severe COVID-19.ConclusionThese findings could suggest an interest in evaluating type 1 IFN treatment in patients with severe COVID-19 and type 1 IFN decline, eventually combined with anti-inflammatory drugs.Clinical trial registrationhttps://clinicaltrials.gov, identifiers NCT04324073, NCT04331808, NCT04341584

Taxonomy based on science is necessary for global conservation

Peer reviewe

Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049