Vertebrate fossils (Pisces and Reptilia) of the Burdigalian deposits from Cala Sant Vicenç (Pollença, Mallorca)

Abstract not availabl

Cabals màxims al Llevant i Migjorn de Mallorca durant les revingudes del setembre de 1989

Abstract not availabl

L’il·lusionista de les alternatives, l’atractiu d’un home intel·ligent: Antonio Estevan (1948-2008)

Abstract not availabl

Unidades deposicionales del Neógeno menorquín

En el Neógeno de Menorca se han diferenciado cinco Unidades deposicionales integradas en dos secuencias. La secuencia inferior comprende una Unidad Basal y una Unidad Detrítica, que registran un ciclo transgresivo - regresivo contemporáneo de una fase diastrófica. Se atribuye al Mioceno inferior y se correlaciona con los depósitos de la misma edad existentes en Mallorca. La secuencia superior comprende tres Unidades. La Unidad Inferior de Barras, discordante sobre la secuencia inferior y sobre el basamento, registra un rápido episodio transgresivo, seguido de una ligera regresión; comprende facies de plataforma progradante hacia el Sur y se atribuye al Tortoniense. Una importante ruptura sedimentaria marca el inicio de la Unidad Arrecifal, que comprende facies de plataforma "off-shore", talud y pared arrecifal y "lagoon"; se atribuye al Tortoniense superior-Messiniense y se correlaciona con el Complejo Arrecifal definido por Esteban (1979). La Unidad Superior de Barras se adosa y/o recubre tanto los taludes de la Unidad Arrecifal como las megalaminas de progradación de la Unidad Inferior de Barras; sus facies corresponden a barras de plataforma y presentan una posición cronoestratigráfica incierta, pudiéndose atribuir tanto al Complejo Terminal messiniense, como incluso al Plioceno.Five depositional units, arranged in two sequences, have been recognized in the Neogene at the island Menorca. The Lower Sequence comprises the "Unidad Basal" (Basal Unit) and the "Unidad Detrítica" (Detritic Unit). This sequence displays a transgressive-regresive cycle coeval with a diastrophic phase. It is a ascribed to Lower Miocene and has been correlated with deposits of the same age at Mallorca. The Upper Sequence comprises three units. The "Unidad Inferior de Barras" (Lower Bar Unit) lies unconformable over the Lower Sequence and over the basement. This unit records a fast transgressive episode followed by a slight regression. The "Unidad Inferior de Barras" comprises facies of a southprograding shelf ascribed to Tortonian. A significant sedimentary break underlines the beginning of the "Unidad Arrecifal" (Reef Unit). This unit comprises offshore shelf facies, reef-talus, reef-wall and lagoon facies. The unit is ascribed to Upper Tortonian-Messinian and is correlated with the Reef Complex defined by ESTEBAN (1979). The "Unidad Superior de Barras" (Upper Bar Unit) is leant against or recoveririg both the talusses of the "Unidad Arrecifal" and the mega-fore:,ets of the prograding "Unidad Inferior de Barras". The facies ccrrespond to shelf bars, displaying an uncertain cronostratigraphic position. They can be attributed to the Messinian Terminal Con-plex or even to the Pliocene

El paleocarst a Mallorca

[cat] Els dipòsits que conformen l’illa de Mallorca són roques carbonatades en una proporció del tot majoritària, principalment calcaries i dolomies. La forta tectonització soferta per aquests materials dins de la complexa estructuració que ha afectat la Mediterrània occidental (corn a part del Tethys) des dels inicis de l’era mesozoica, ha propiciat al llarg dels temps geològics diverses etapes d'emersió del materials carbonatats que han donat lloc al desenvolupament d'importants fenòmens paleocàrstics. Entre aquests períodes destaca -a part de puntuals emersions d'edat intrajuràssica- la fi del Cretaci i el començament del Paleogen, quan va tenir lloc la carstificació de bona part de les calcaries del Juràssic inferior. Aquest paleocarst desenvolupat bàsicament sobre el Lias, així com el desenvolupat al Miocè superior i que afecta les calcaries esculloses del Miocè terminal, són els exemples més espectaculars que poden ser estudiats a Mallorca.[eng] The deposits building up the island of Mallorca are nearly on the whole of limestone and dolomite lithologies. These materials underwent a strong tectonization due to the complex structuration that affected the western Mediterranean (as part of the Tethys) since the beginning of the Mesozoic era. These processes have propitiated, throughout the geological times, some events of emersion of the carbonate materials, which have given way to the development of important paleokarstic phenomena. Among these periods -apart from eventual emersions of intrajurassic age- the final Cretaceous and most of the Paleogene stand out, when great part of the Lower Jurassic limestones were karstified. Such paleokarsts developed basically on Lias deposits, as well as that formed during the Upper Miocene, which affected the reefal limestones from the terminal Miocene, are the most spectacular examples to be studied in Mallorca

Comparison of global responses to mild deficiency and excess copper levels in Arabidopsis seedlings

[EN] Copper is an essential micronutrient in higher plants, but it is toxic in excess. The fine adjustments required to fit copper nutritional demands for optimal growth are illustrated by the diverse, severe symptoms resulting from copper deficiency and excess. Here, a differential transcriptomic analysis was done between Arabidopsis thaliana plants suffering from mild copper deficiency and those with a slight copper excess. The effects on the genes encoding cuproproteins or copper homeostasis factors were included in a CuAt database, which was organised to collect additional information and connections to other databases. The categories overrepresented under copper deficiency and copper excess conditions are discussed. Different members of the categories overrepresented under copper deficiency conditions were both dependent and independent of the general copper deficiency transcriptional regulator SPL7. The putative regulatory elements in the promoter of the copper deficiency overrepresented genes, particularly of the iron superoxide dismutase gene FSD1, were also analysed. A 65 base pair promoter fragment, with at least three GTAC sequences, was found to be not only characteristic of them all, but was responsible for most of the FSD1 copper-dependent regulations. Moreover, a new molecular marker for the slight excess copper nutritional status is proposed. Taken together, these data further contribute to characterise copper nutritional responses in higher plants.We thank Dr Toshiharu Shikanai for the spl7 mutant and the Unitat d'Analisi Elemental, Serveis Cientificotecnics at the Universitat de Barcelona. This work has been supported by Grants BIO2011-24848 and CSD2007-00057 to L.P. from the Spanish Ministry of Economy and Competitiveness, and by FEDER funds from the European Union and the Generalitat Valenciana (Regional Valencian Government; ACOMP07-159). N.A.-C., A.G.-M. and A.P.-G were recipients of predoctoral fellowships from the Spanish Ministry of Economy and Competitiveness.Andres-Colas, N.; Perea García, A.; Mayo, S.; Garcia-Molina, A.; Dorcey, E.; Rodríguez-Navarro, S.; Perez Amador, MA.... (2013). Comparison of global responses to mild deficiency and excess copper levels in Arabidopsis seedlings. Metallomics. 5(9):1234-1246. https://doi.org/10.1039/c3mt00025g123412465

A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

Funder: Fundación Científica Asociación Española Contra el Cáncer (ES)Funder: Cancer Focus Northern Ireland and Department for Employment and LearningFunder: Intramural Research Program of the Division of Cancer Epidemiology and Genetics, National Cancer Institute, USAAbstract: Background: Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% of the phenotypic variance. Methods: We complemented a new conventional PC GWAS (1D) with genome spatial autocorrelation analysis (2D) permitting to prioritize low frequency variants not detected by GWAS. These were further expanded via Hi-C map (3D) interactions to gain additional insight into the inherited basis of PC. In silico functional analysis of public genomic information allowed prioritization of potentially relevant candidate variants. Results: We identified several new variants located in genes for which there is experimental evidence of their implication in the biology and function of pancreatic acinar cells. Among them is a novel independent variant in NR5A2 (rs3790840) with a meta-analysis p value = 5.91E−06 in 1D approach and a Local Moran’s Index (LMI) = 7.76 in 2D approach. We also identified a multi-hit region in CASC8—a lncRNA associated with pancreatic carcinogenesis—with a lowest p value = 6.91E−05. Importantly, two new PC loci were identified both by 2D and 3D approaches: SIAH3 (LMI = 18.24), CTRB2/BCAR1 (LMI = 6.03), in addition to a chromatin interacting region in XBP1—a major regulator of the ER stress and unfolded protein responses in acinar cells—identified by 3D; all of them with a strong in silico functional support. Conclusions: This multi-step strategy, combined with an in-depth in silico functional analysis, offers a comprehensive approach to advance the study of PC genetic susceptibility and could be applied to other diseases

Unidades deposicionales del Neógeno menorquín

En el Neógeno de Menorca se han diferenciado cinco Unidades deposicionales integradas en dos secuencias. La secuencia inferior comprende una Unidad Basal y una Unidad Detrítica, que registran un ciclo transgresivo - regresivo contemporáneo de una fase diastrófica. Se atribuye al Mioceno inferior y se correlaciona con los depósitos de la misma edad existentes en Mallorca. La secuencia superior comprende tres Unidades. La Unidad Inferior de Barras, discordante sobre la secuencia inferior y sobre el basamento, registra un rápido episodio transgresivo, seguido de una ligera regresión; comprende facies de plataforma progradante hacia el Sur y se atribuye al Tortoniense. Una importante ruptura sedimentaria marca el inicio de la Unidad Arrecifal, que comprende facies de plataforma "off-shore", talud y pared arrecifal y "lagoon"; se atribuye al Tortoniense superior-Messiniense y se correlaciona con el Complejo Arrecifal definido por Esteban (1979). La Unidad Superior de Barras se adosa y/o recubre tanto los taludes de la Unidad Arrecifal como las megalaminas de progradación de la Unidad Inferior de Barras; sus facies corresponden a barras de plataforma y presentan una posición cronoestratigráfica incierta, pudiéndose atribuir tanto al Complejo Terminal messiniense, como incluso al Plioceno.Five depositional units, arranged in two sequences, have been recognized in the Neogene at the island Menorca. The Lower Sequence comprises the "Unidad Basal" (Basal Unit) and the "Unidad Detrítica" (Detritic Unit). This sequence displays a transgressive-regresive cycle coeval with a diastrophic phase. It is a ascribed to Lower Miocene and has been correlated with deposits of the same age at Mallorca. The Upper Sequence comprises three units. The "Unidad Inferior de Barras" (Lower Bar Unit) lies unconformable over the Lower Sequence and over the basement. This unit records a fast transgressive episode followed by a slight regression. The "Unidad Inferior de Barras" comprises facies of a southprograding shelf ascribed to Tortonian. A significant sedimentary break underlines the beginning of the "Unidad Arrecifal" (Reef Unit). This unit comprises offshore shelf facies, reef-talus, reef-wall and lagoon facies. The unit is ascribed to Upper Tortonian-Messinian and is correlated with the Reef Complex defined by ESTEBAN (1979). The "Unidad Superior de Barras" (Upper Bar Unit) is leant against or recoveririg both the talusses of the "Unidad Arrecifal" and the mega-fore:,ets of the prograding "Unidad Inferior de Barras". The facies ccrrespond to shelf bars, displaying an uncertain cronostratigraphic position. They can be attributed to the Messinian Terminal Con-plex or even to the Pliocene

Effects of a polysaccharide-based multiingredient supplement on salivary immunity in non-elite marathon runners

Peer Reviewe

Atles de les Illes Balears

Resumen tomado parcialmente del propio recursoSe presenta un atlas en formato multimedia, el primero editado en la comunidad autónoma de las Islas Baleares, destinado a conocer desde el punto de vista geográfico el territorio insular y a recoger en formato digital buena parte del trabajo realizado y editado bajo el mismo título, en soporte tradicional, en el año 1995. Se pretende construir un currículum propio sobre el medio y las ciencias sociales en las Islas Baleares. Incluye mapas topográficos, geografía física y humana y materiales didácticos. Se analizan las características físicas y humanas del territorio insular, tanto el medio como las interrelaciones económicas, sociales y culturales, entre otras, que se generan a partir de la huella humana. Constituye una herramienta didáctica tanto en la educación universitaria como no-universitaria, por parte del alumno y como material de trabajo del profesorado puesto que en la mayoría de temas se llega a un nivel de profundidad elevado.BalearesES