131 research outputs found

    Biblioteca UniCosta y REDICUC conservan el patrimonio material e inmaterial del Departamento

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    Los motivos que enmarcan la formulación de este proyecto es el peligro al que está expuesto el pueblo indígena Mokaná, en Tubará (Atlántico). El riesgo de la pérdida total de sus vestigios y legados ancestrales está latente: ya perdieron la lengua, y líderes culturales como el señor Evaristo Mendoza y su familia han abanderado significativos procesos de corte patrimonial hasta hoy invisibilizados. Por la edad del señor Evaristo Mendoza -mejor conocido como ‘El último gaitero Mokaná’, urge un reconocimiento y estudio de su herencia musical…es un tesoro vivo, ¡un ícono de la riqueza atlanticense! Además, no se hallan referencias bibliográficas actualizadas sobre este grupo humano y es muy poco el material de rigurosidad técnica y científica disponible. El más reciente es de inicios de 2018, realizado por estudiantes de pregrado de la Pontificia Universidad Javeriana (Bogotá) titulado ‘Cantos de monte: resonancias audiovisuales del encuentro entre los paisajes sonoros de tres comunidades indígenas en el Atlántico colombiano’

    Effect of carob (Ceratonia siliqua L.) seed in broiler chick diets on nutrient digestibility and intestinal viscosity.

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    La inclusión de garrofín a niveles de 60 (ración CS-60) y 90 g/kg (ración CS-90) en una ración referencia produjo una marcada (P<O.O1) disminución de la utilización de los nutrientes. La reducción en la digestibilidad aparente de la proteína bruta y de la grasa bruta fue del 12.7 y 20.9% en la ración CS-60, y del 29.5 y 23.8% en la ración CS-90, respectivamente. La energía metabolizable aparente disminuyó siguiendo una tendencia similar a la observada en la digestibilidad de la grasa bruta. La viscosidad de la digesta en el yeyuno se incrementó acusadamente por la presencia de garrofín en la ración, lo que podría explicar la mayoría de los resultados obtenidos en este estudio.// lnclusion of carob seed at levels of 60 (CS-60 diet) and 90 glkg (CS-90 diet) in a reference diet caused a marked (P<O.Ol) depression in the utilization of nutrients. The reduction in the apparent digestibility of crude protejo and crude fat was 12.7 and 20.9% for CS-60 diet, and 29.5 and 23.8% for CS-90 diet, respectively. The apparent metabolizable energy value followed a similar depressing trend than that observed for crude fat digestibility. Viscosity of the jejunal digesta was drastically increased by the presence of carob seed in the diet, and it might explain most of the results obtained in this study

    Deep Sequential Models for Suicidal Ideation from Multiple Source Data

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    This paper presents a novel method for predicting suicidal ideation from electronic health records (EHR) and ecological momentary assessment (EMA) data using deep sequential models. Both EHR longitudinal data and EMA question forms are defined by asynchronous, variable length, randomly sampled data sequences. In our method, we model each of them with a recurrent neural network, and both sequences are aligned by concatenating the hidden state of each of them using temporal marks. Furthermore, we incorporate attention schemes to improve performance in long sequences and time-independent pre-trained schemes to cope with very short sequences. Using a database of 1023 patients, our experimental results show that the addition of EMA records boosts the system recall to predict the suicidal ideation diagnosis from 48.13% obtained exclusively from EHR-based state-of-the-art methods to 67.78%. Additionally, our method provides interpretability through the t-distributed stochastic neighbor embedding (t-SNE) representation of the latent space. Furthermore, the most relevant input features are identified and interpreted medically.This work was supported in part by the Spanish MINECO under Grants TEC2015-69868-C2-1-R, TEC2016-78434-C3-3-R, and TEC2017-92552-EXP, in part by Spanish MICINN under Grant RTI2018-099655-B-I00, in part by Comunidad de Madrid under Grants IND2017/TIC-7618, IND2018/TIC-9649, Y2018/TCS-4705, and B2017/BMD-3740 AGES-CM 2CM, in part by BBVA Foundation under Deep-DARWiN - FBBVA Grant for scientific research teams 2018, in part by ISCIII under Grant PI16/01852, and in part by AFSP under Grant LSRG-1-005-16

    Biomasa de Eucalyptus globulus como materia prima en la obtención de biocombustible líquido

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    Atmospheric pollution and accelerated environmental deterioration for the increasing use of fossil fuels have directed research in&nbsp;the&nbsp;energy field towards the search for alternative, renewable, efficient and, above all, more environmentally friendly sources. Among the raw materials that are of great interest in the generation of biofuels are lignocellulosic residues, which are currently produced in abundant quantities, either by the simple action of nature or because they are part of the agro-industrial chain of a given region. For this reason, in the present work, the biomass of&nbsp;Eucalyptus globulus&nbsp;was evaluated as a low-cost and widely available source for obtaining liquid biofuel, for which a preliminary physical and chemical characterization was carried out, by considering established standard specifications. Thermochemical conversion tests were carried out by pyrolysis in an N2&nbsp;atmosphere and through the application of a factorial experimental design (22) contemplating the influence of experimental variables such as residence time and temperature, it was possible to obtain at 550 ºC and during 20 min of reaction, a bio-oil with a maximum yield of 45,2% and whose physical and chemical properties are within the range estimated in the literature for biofuels of lignocellulosic origin, such as the calorific value (16,7 MJ /kg). Therefore, the biomass of&nbsp;Eucalyptus globulus&nbsp;can be considered as a raw material with potential to be explored in the generation of energy.&nbsp;La contaminación atmosférica y el acelerado deterioro ambiental por el creciente uso de combustibles fósiles, ha direccionado las investigaciones en el campo energético hacía la búsqueda de fuentes alternativas, renovables, eficientes y sobre todo más amigables con el medio ambiente. Entre la materia prima que cobra gran interés en la generación de biocombustibles, se encuentran los residuos lignocelulósicos que actualmente se producen en abundantes cantidades, ya sea por simple acción de la naturaleza o porque hacen parte de la cadena agroindustrial de una región dada. Es por ello que en el presente trabajo se evaluó la biomasa de Eucalyptus globulus, como fuente de bajo costo y amplia disponibilidad en la obtención de biocombustible líquido, para lo cual se llevó a cabo una caracterización física y química preliminar teniendo en cuenta especificaciones establecidas en normatividad del sector. Se realizaron ensayos de conversión termoquímica por medio de una pirólisis en atmósfera de N2 y a través de la aplicación de un diseño experimental factorial ( ) contemplando la influencia de variables experimentales tales como tiempo de residencia y temperatura, fue posible obtener a 550 ºC y durante 20 min de reacción, un bioaceite con un rendimiento máximo del 45,2 % y cuyas propiedades físicas y químicas se encuentran dentro del rango estimado en literatura para biocombustibles de origen lignocelulósico, tal es el caso del poder calorífico (16,7 MJ/kg). Por lo tanto, la biomasa de Eucalyptus globulus puede ser considerada como materia prima con potencial a ser explorado en la generación de energéticos. 

    Momento Económico (50)

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    En este número: Historia y Modernización. El Programa de Ciencia y Modernización Tecnológica, 1990-1994. Algunos comentarios generales al Programa de Ciencia y Modernización Tecnológica 1990-1994. Los objetivos del Programa Nacional de Población 1989-1994. La movilidad urbana en la Ciudad de México. Importación de leche en polvo en México: la utopía de la autosuficiencia lechera. América Latina: aspectos de la década perdida. Notas sobre la modernización agroindustrial. ¿Qué es el Estado ex-socialista ?. La investigación nacional y el Congreso Universitario. Temas de hoy

    Effect of dietary high-oleic acid and conventional sunflower seeds and their refined oils on fatty acid composition of adipose tissue and meat in broiler chickens

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    The influence of different dietary fat source on performance, tissue fatty acid composition (abdominal fat, thigh and breast muscles) and abdominal fat melting point was evaluated in femaJe broiler chickens. Birds were red diets containing 80 g/kg of added fat by the inclusion ofhigh-oJeic acid sunflower secd (HOASS) and conventionaJ sunflower seed (CSS), their respective refined oiJs (HOASO and CSO) and lard during three weeks (from 2\ to 42 d of agc). Feed efficiency was significantly impaired by the inclusion ofHOASS and CSS in diet when compared with HOASO, CSO and lard. The levcls of the majar fatty acids (palmitic, oleic and linoleic) in cach animal tissue reflectcd the fatty acid profilc of the dietary fat (r2 >0.83). The linear regression analysis between fatty acid content ami mclting point of abdominal fat gave the highest coefficient of determination for thc saturated fatty acid contcnt (r2=0.80). It is concluded that the seeds ofhigh-oleic acid and conventional varieties orsunflower might be used in poultry feeding in arder to increase, rcspectively, monounsaturated and polyunsaturatcd fatty acid contents in both abdominal adipose tissue and intramuscular fato The feeding ofboth types of seeds had similar effects to their respective refined oils on the unsaturated to saturatcd rally acid ratio ofthe chicken tissues and on the melting point of abdominal fato NevcrtheJess, thcy showed a ncgative influence on fat firmness when compared with the dietary inclusion of lard

    Aproximación a la Geografía del despilfarro en España: balance de las últimas dos décadas

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    Este trabajo pretende ser una primera aproximación a la dimensión del despilfarro de recursos públicos en infraestructuras en España desde 1995 hasta la actualidad en los distintos niveles de gobierno. A partir de algunas precisiones sobre los conceptos de despilfarro y corrupción, se analiza, de una parte, la inversión y los sobrecostes en infraestructuras innecesarias impulsadas y ejecutadas por la Administración General del Estado en el ámbito de sus competencias, y de otra, infraestructuras, proyectos, eventos e inversiones fallidas, vacías o infrautilizadas acometidas por las Comunidades Autónomas y los gobiernos locales. Se abordan los déficit de marco institucional y de gobernanza territorial y se sugiere una posible agenda de reformas a partir de unas conclusiones generales

    Increased risk of MAFLD and liver fibrosis in inflammatory bowel disease independent of classic metabolic risk factors

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    ackground & Aims There is conflicting evidence regarding the prevalence of and risk factors for metabolic-associated fatty liver disease (MAFLD) in patients with inflammatory bowel disease (IBD). We aimed to determine MAFLD prevalence and risk factors in IBD patients. Methods Cross-sectional, case-control study included all consecutive IBD patients treated at 2 different university hospitals. Controls were subjects randomly selected from the general population and matched by age, sex, type 2 diabetes status, and body mass index in a 1:2 ratio. MAFLD was confirmed by controlled attenuation parameter. Liver biopsies were collected when MAFLD with significant liver fibrosis was suspected. In addition, age- and fibrosis stage-paired non-IBD patients with biopsy-proven MAFLD served as a secondary control group. Results Eight hundred thirty-one IBD patients and 1718 controls were included. The prevalence of MAFLD and advanced liver fibrosis (transient elastography ≥9.7 kPa) was 42.00% and 9.50%, respectively, in IBD patients and 32.77% and 2.31%, respectively, in the general population (P < .001). A diagnosis of IBD was an independent predictor of MAFLD (adjusted odds ratio, 1.99; P < .001) and an independent risk factor for advanced liver fibrosis (adjusted odds ratio, 5.55; P < .001). Liver biopsies were obtained from 40 IBD patients; MAFLD was confirmed in all cases, and fibrosis of any degree was confirmed in 25 of 40 cases (62.5%). Body mass index and type 2 diabetes prevalence were significantly lower in IBD-MAFLD patients than in severity-paired patients with biopsy-proven MAFLD. Conclusions MAFLD and liver fibrosis are particularly prevalent in IBD patients, regardless of the influence of classic metabolic risk factors.Acknowledgements: The authors report funding support from the Spanish Instituto de Salud Carlos III-FEDER Grant (FIS - PI18/01304) related to this manuscript

    Late gadolinium enhancement distribution patterns in non-ischemic dilated cardiomyopathy: Genotype-phenotype correlation.

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    AIMS Late gadolinium enhancement (LGE) is frequently found in patients with dilated cardiomyopathy (DCM), there is little information about its frequency and distribution pattern according to underlying genetic substrate. We sought to describe LGE patterns according to genotype and to analyze the risk of major ventricular arrhythmias (MVA) according to patterns. METHODS AND RESULTS Cardiac magnetic resonance findings and LGE distribution according to genetics was performed in a cohort of 600 DCM patients followed at 20 Spanish centers. After exclusion of individuals with multiple causative gene variants or with variants in infrequent DCM-causing genes, 577 patients (34% females, mean age 53.5 years, LVEF 36.9 ± 13.9%) conformed the final cohort. A causative genetic variant was identified in 219 (38%) patients and 147 (25.5%) had LGE. Significant differences were found comparing LGE patterns between genes (P < 0.001). LGE was absent or rare in patients with variants in TNNT2, RBM20 and MYH7 (0%, 5% and 20%, respectively). Patients with variants in DMD, DSP and FLNC showed predominance of LGE subepicardial pattern (50%, 41% and 18%, respectively) whereas patients with variants in TTN, BAG3, LMNA and MYBPC3 showed unspecific LGE patterns. Genetic yield differed according to LGE pattern. Patients with subepicardial, lineal midwall, transmural, right ventricular insertion points or with combination of LGE patterns showed increased risk of MVA compared with patients without LGE. CONCLUSION LGE patterns in DCM has a specific distribution according to the affected gene. Certain LGE patterns are associated with increased risk of MVA and with increased yield of genetic testing.This study has been funded by Instituto Salud Carlos III (ISCIII) through the projects ‘PI18/0004, PI19/01283, and PI20/0320’ (co-funded by the European Regional Development Fund/European Social Fund ‘A way to make Europe’/‘Investing in your future’). The Hospital Universitario Puerta de Hierro, the Hospital Universitario Vall Hebrón, the Hospital General Universitario Gregorio Marañón, and the Hospital Universitario Virgen de la Arrixaca are members of the European Reference Network for Rare, Low Prevalence, and Complex Diseases of the Heart (ERN GUARD-Heart). F.d.F. receives grant support from ISCIII (CM20/00101). R.B. receives funding from the Obra Social la Caixa Foundation. M.B. receives funding from ISCIII (PI19/01283). The CNIC is supported by the ISCIII, Ministerio de Ciencia e Innovación of the Spanish Government (MCIN), and Pro CNIC Foundation.S
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