Cambios en la discapacidad de las personas mayores entre 1999 y 2008 en España

Utilizando los microdatos de las encuestas de discapacidad del INE, este trabajo analiza cómo ha cambiado la prevalencia total y según categorías de la discapacidad de las personas mayores en España, entre 1999 y 2008, y cómo lo hace en los distintos grupos de edad. Se observa un aumento de la prevalencia entre ambos años, pero una mejora respecto a lo esperado. Esta mejora relativa no es homogénea: se ha reducido mucho la prevalencia de discapacidad instrumental (la más frecuente), y ello en todas las edades, pero ha aumentado la prevalencia en la categoría más severa de actividades básicas y especialmente entre las personas muy mayores.Peer reviewe

CIMAR, NIMAR, and LMMA: novel algorithms for thread and memory migrations in user space on NUMA systems using hardware counters

This paper introduces two novel algorithms for thread migrations, named CIMAR (Core-aware Interchange and Migration Algorithm with performance Record –IMAR–) and NIMAR (Node-aware IMAR), and a new algorithm for the migration of memory pages, LMMA (Latency-based Memory pages Migration Algorithm), in the context of Non-Uniform Memory Access (NUMA) systems. This kind of system has complex memory hierarchies that present a challenging problem in extracting the best possible performance, where thread and memory mapping play a critical role. The presented algorithms gather and process the information provided by hardware counters to make decisions about the migrations to be performed, trying to find the optimal mapping. They have been implemented as a user space tool that looks for improving the system performance, particularly in, but not restricted to, scenarios where multiple programs with different characteristics are running. This approach has the advantage of not requiring any modification on the target programs or the Linux kernel while keeping a low overhead. Two different benchmark suites have been used to validate our algorithms: The NAS parallel benchmark, mainly devoted to computational routines, and the LevelDB database benchmark focused on read–write operations. These benchmarks allow us to illustrate the influence of our proposal in these two important types of codes. Note that those codes are state-of-the-art implementations of the routines, so few improvements could be initially expected. Experiments have been designed and conducted to emulate three different scenarios: a single program running in the system with full resources, an interactive server where multiple programs run concurrently varying the availability of resources, and a queue of tasks where granted resources are limited. The proposed algorithms have been able to produce significant benefits, especially in systems with higher latency penalties for remote accesses. When more than one benchmark is executed simultaneously, performance improvements have been obtained, reducing execution times up to 60%. In this kind of situation, the behaviour of the system is more critical, and the NUMA topology plays a more relevant role. Even in the worst case, when isolated benchmarks are executed using the whole system, that is, just one task at a time, the performance is not degradedThis research work has received financial support from the Ministerio de Ciencia e Innovación, Spain within the project PID2019-104834GB-I00. It was also funded by the Consellería de Cultura, Educación e Ordenación Universitaria of Xunta de Galicia (accr. 2019–2022, ED431G 2019/04 and reference competitive group 2019–2021, ED431C 2018/19)S

The Structural and Intercultural Competence for Epidemiological Studies (SICES) guidelines: A 22-item checklist

Structural and intercultural competence approaches have been widely applied to fields such as medical training, healthcare practice, healthcare policies and health promotion. Nevertheless, their systematic implementation in epidemiological research is absent. Based on a scoping review and a qualitative analysis, in this article we propose a checklist to assess cultural and structural competence in epidemiological research: the Structural and Intercultural Competence for Epidemiological Studies guidelines. These guidelines are organised as a checklist of 22 items and consider four dimensions of competence (awareness and reflexivity, cultural and structural validation, cultural and structural sensitivity, and cultural and structural representativeness), which are applied to the different stages of epidemiological research: (1) research team building and research questions; (2) study design, participant recruitment, data collection and data analysis; and (3) dissemination. These are the first guidelines addressing structural and cultural competence in epidemiological inquiryThis project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement no 825884 (SYNergies for Cohorts in Health: integrating the ROle of all Stakeholders, SYNCHROS). AM-H acknowledges the financial support from Institut Català de la Recerca i Estudis Avançats (ICREA) under the ICREA Academia Awar

Worldwide mapping of initiatives that integrate population cohorts

[Resumen no disponible

Wideband channel modeling for mm-wave inside trains for 5G-related applications

Passenger trains and especially metro trains have been identified as one of the key scenarios for 5G deployments. The wireless channel inside a train car is reported in the frequency range between 26.5GHz and 40GHz. These bands have received a lot of interest for high-density scenarios with a high-traffic demand, two of the most relevant aspects of a 5G network. In this paper we provide a full description of the wideband channel estimating Power-Delay Profiles (PDP), Saleh-Valenzuela model parameters, time-of-arrival (TOA) ranging, and path-loss results.Moreover, the performance of an automatic clustering algorithm is evaluated. The results show a remarkable degree of coherence and general conclusions are obtained.Enabling 5G TEC2014-55735-C3-2-R is funded by the Spanish Ministry of Economy and Competitiveness and also is funded by the Chinese Strategic International Cooperative Project of National key R&D Plan, 2016YFE0200200

Automatic imagine analyzer to assess retinal vessel caliber (Altair) tool validation for the analysis of retinal vessels

Objective: To assess the reliability and validity of the tool Automatic image analyzer to assess retinal vessel caliber (ALTAIR) to analyze the vascularization of the retina and cardiovascular risk prediction. Design and method: Cross-sectional of tools validation study. We included 250 subjects in total, aged 62 +/- 9 years, 51% males. We have made a validation of reliability analyzing the intraclass correlation (ICC) intra observer, inter observer and inter device (compared with AVindex calculator) to the thickness, area and length of arteries and veins of the retina in 3 concentric circles from the disc in 120 retinographies. The concurrent validity was performed with 250 subjects and 497 retinographies, analyzing the relationship with age, blood pressure, parameters of vascular structure and function, renal function and cardiovascular risk estimated with scales. Results: In the sample, the 32% are obese, 68% hypertensive and 17% diabetic. The interobserver ICC for thickness, area and length of veins and arteries ranged from 0.809 to length of arteries to 0.916 to veins area. The intra observer ICC for intra thickness, area and length of veins and arteries ranged from 0.640 for the length of the veins and 0.906 for the area of the arteries and the inter device ICC was for arteriovenous ratio (AVR) 0.887, thickness of arteries 0.590 and veins thickness 0.677. We found a moderate correlation of the age (r between 0.30 and 0.50, p < 0.001) with the retinal vascular parameters analyzed. In multiple linear regression analysis after adjusting for age and sex, the association of AVR and arterial thickness with the diastolic blood pressure and albumin creatinine ratio and arterial area and length with systolic arterial blood pressure and carotid intima-media thickness remains. Also the thickness area and length of the vessels show an association with cardiovascular risk estimated SCORE scale. Conclusions: The ALTAIR tool shows a good reliability in the concordance inter observers, intra observer and inter device measurements and a concordant validity to show an association with vascular parameters, target organ damage and cardiovascular risk

Prevalence of dementia and major dementia subtypes in Spanish populations: A reanalysis of dementia prevalence surveys, 1990-2008

Background This study describes the prevalence of dementia and major dementia subtypes in Spanish elderly. Methods We identified screening surveys, both published and unpublished, in Spanish populations, which fulfilled specific quality criteria and targeted prevalence of dementia in populations aged 70 years and above. Surveys covering 13 geographically different populations were selected (prevalence period: 1990-2008). Authors of original surveys provided methodological details of their studies through a systematic questionnaire and also raw age-specific data. Prevalence data were compared using direct adjustment and logistic regression. Results The reanalyzed study population (aged 70 year and above) was composed of Central and North-Eastern Spanish sub-populations obtained from 9 surveys and totaled 12,232 persons and 1,194 cases of dementia (707 of Alzheimer's disease, 238 of vascular dementia). Results showed high variation in age- and sex-specific prevalence across studies. The reanalyzed prevalence of dementia was significantly higher in women; increased with age, particularly for Alzheimer's disease; and displayed a significant geographical variation among men. Prevalence was lowest in surveys reporting participation below 85%, studies referred to urban-mixed populations and populations diagnosed by psychiatrists. Conclusion Prevalence of dementia and Alzheimer's disease in Central and North-Eastern Spain is higher in females, increases with age, and displays considerable geographic variation that may be method-related. People suffering from dementia and Alzheimer's disease in Spain may approach 600,000 and 400,000 respectively. However, existing studies may not be completely appropriate to infer prevalence of dementia and its subtypes in Spain until surveys in Southern Spain are conductedFinancial aid was obtained from the Spanish RECSP C03-09, CIEN C03-06 and CIBERNED networks, and from the Pfizer Foundation in particularS

Transitions and trajectories in frailty states over time: a systematic review of the European Joint Action ADVANTAGE

Introduction. Frailty is a dynamic syndrome and may be reversible. Despite this, little is known about trajectories or transitions between different stages of frailty. Methods. A systematic review was conducted, selecting studies reporting frailty trajectories or transition states for adults in any settings in European ADVANTAGE Joint Action Member States. Results. Only three papers were included. Data were from longitudinal communitybased cohorts in the United Kingdom, Netherlands and Italy. The English study investigated the effect of physical activity on the progression of frailty over a 10-year period. Two presented data on the proportion of participants experiencing at least one frailty transition over time (32.6% in the Italian sample aged ≥ 65 years followed for 4.4 years; 34.3% in the Dutch sample aged 65-75 years, followed for 2 years). Conclusions. Data on frailty trajectories and transition states were limited and heterogeneous. Well-designed prospective studies and harmonized approaches to data collection are now needed

Incidence of frailty: a systematic review of scientific literature from a public health perspective

Introduction. Because of the dynamic nature of frailty, prospective epidemiological data are essential to calibrate an adequate public health response. Methods. A systematic review of literature on frailty incidence was conducted within the European Joint Action ADVANTAGE. Results. Of the 6 studies included, only 3 were specifically aimed at estimating frailty incidence, and only 2 provided disaggregated results by at least gender. The mean followup length (1-22.2 years; median 5.1), sample size (74-6306 individuals), and age of participants (≥ 30-65) varied greatly across studies. The adoption of incidence proportions rather than rates further limited comparability of results. After removing one outlier, incidence ranged from 5% (follow-up 22.2 years; age ≥ 30) to 13% (follow-up 1 year, age ≥ 55). Conclusions. Well-designed prospective studies of frailty are necessary. To facilitate comparison across studies and over time, incidence should be estimated in person-time rate. Analyses of factors associated with the development of frailty are needed to identify high-risk groups

Prevalence of frailty at population level in European ADVANTAGE Joint Action Member States: a systematic review and meta-analysis

Introduction. Although frailty is common among community-dwelling older adults, its prevalence in Europe and how this varies between countries is unclear. Methods. A systematic review and meta-analysis of literature on frailty prevalence in 22 European countries involved in the Joint Action ADVANTAGE was conducted. Results. Sixty-two papers, representing 68 unique datasets were included. Meta-analysis showed an overall estimated frailty prevalence of 18% (95% confidence interval, CI, 15- 21%). The prevalence in community (n = 53) vs non-community based studies (n = 15) was 12% (95% CI 10-15%) and 45% (95% CI 27-63%), respectively. Pooled prevalence in community studies adopting a physical phenotype was 12% (95% CI 10-14%, n = 45) vs 16% (95% CI 7-29%, n = 8) for all other definitions. Sub-analysis of a subgroup of studies assessed as high-quality (n = 47) gave a pooled estimate of 17% (95% CI 13-21%). Conclusions. The considerable and significant heterogeneity found warrants the development of common methodological approaches to provide accurate and comparable frailty prevalence estimates at population-level