Fantasmas: un tema común y dos desarrollos diferentes en las tradiciones literarias japonesa e hispánica

RESUMEN: los cuentos de fantasmas han tenido un gran número de lectores a lo largo de la historia y se han producido en todas las culturas. En el presente trabajo, a partir de una selección de relatos, analizaremos la figura del fantasma desde la perspectiva de dos tradiciones literarias diferentes: la de los cuentos de terror hispánicos decimonónicos y la de los kaidan del período Edo japonés. De este modo, conoceremos con qué rasgos han dotado a sus espectros los autores de cada tradición con el fin de alcanzar un objetivo último que trasciende sus diferencias espaciales y temporales: provocar el terror en el lector

Cytochrome cM is probably a membrane protein similar to the C subunit of the bacterial nitric oxide reductase

Cytochrome cM was first described in 1994 and its sequence has been found in the genome of manifold cyanobacterial species ever since. Numerous studies have been carried out with the purpose of determining its function, but none of them has given place to conclusive results so far. Many of these studies are based on the assumption that cytochrome cM is a soluble protein located in the thylakoid lumen of cyanobacteria. In this work, we have reevaluated the sequence of cyto-chrome cM, with our results showing that its most probable 3D structure is strongly similar to that of the C subunit of the bacterial nitric oxide reductase. The potential presence of an α-helix tail, which could locate this protein in the thylakoid membrane, further supports this hypothesis, thus providing a new, unexpected role for this redox protein.Fundación Investigación Universidad de Sevilla FIUS0571000

Fagus sylvatica and Quercus pyrenaica: Two neighbors with few things in common

[EN] The Iberian Peninsula comprises one of the largest boundaries between Mediterranean and Eurosiberian vegetation, known as sub-Mediterranean zone. This ecotone hosts many unique plant species and communities and constitutes the low-latitude (warm) margin of numerous central European species which co-occur with Mediterranean vegetation. Two of the main species found in this region are the Eurosiberian European beech (Fagus sylvatica L.) and the Mediterranean Pyrenean oak (Quercus pyrenaica Willd.). It remains unclear how the different physiological and adaptive strategies of these two species reflect their niche partitioning within a sub-Mediterranean community and to what extent phenotypic variation (intraspecific variability) is driving niche partitioning across Eurosiberian and Mediterranean speciesS

Propuestas didácticas de carácter interdisciplinar para la enseñanza/Aprendizaje del espacio y el tiempo en la educación infantil

En este artículo se desarrollan propuestas didácticas de carácter interdisciplinar que el maestro de educación infantil puede aplicar en su práctica educativa para conseguir que niños y niñas interioricen las nociones de espacio y tiempo. Estas propuestas se enmarcan en el ámbito del conocimiento del entorno natural y social, que en esta etapa educativa no se configura como un área independiente. Se parte de la idea de que el propio cuerpo es el primer punto de referencia de la percepción y que desde la percepción del propio esquema corporal se llegará a dominar la percepción del espacio representativo. En la segunda parte, ampliamos el horizonte espacial e introducimos las nociones temporales, en base a la percepción que el niño tiene de los cambios que se producen en su entorno cercano, especialmente de los cambios rítmicos (rutinas en el día, cambios estacionales, cambios en la familia…). Por último, en la tercera parte, se plantea el descubrimiento, correcta percepción y comprensión por parte del niño, de un espacio más amplio: en la calle, el barrio, el pueblo o la ciudad. Cada uno de los tres apartados se acompaña de propuestas didácticas que permiten implementar y llevar a la práctica con facilidad, las argumentaciones teóricasIn this article we present interdisciplinary educational proposals that young children teachers could apply in their educational practice to ensure that children internalize the notions of space and time. These proposals concern the natural and the social environments, which in this level of education are not considered independent areas but one complex field. Each proposal contains specific activities with a theoretical basis which justifies them. We start in the first part from the concept that for human beings the body is the first benchmark of perception. From the perception of the body scheme itself, we finally acknowledge representative space. Then, in the second part, we expand the field and introduce temporal notions, taking into account the perception that children have of changes that occur in their immediate environment, especially recurrent changes (routines during the day, seasonal changes, within the family...). Finally, in the third part, we elaborate on the discovery, correct perception and understanding by the child, of a wider space: the street, the neighborhood, the town or cit

Effect of rowing on mobility, functionality, and quality of life in women with and without breast cancer: a 4-month intervention

Purpose: Of the different modalities of rowing, dragon boat training is the most analyzed in breast cancer (BC). However, other types of boats, such as the felucca, use different biomechanical techniques, which have not been studied in the scientific literature. Consequently, in this study, we sought to determine the benefits of felucca rowing on the physical, psychological, and emotional well-being of patients with BC and healthy persons. Methods: A pre- and post-intervention, single-arm study without a control group with a 4-month intervention was carried out in Spain in 2019. The study sample included six women with BC and 15 healthy women. The following questionnaires were administered before and after the intervention: Disabilities of the Arm, Shoulder, and Hand (DASH), Constant-Murley score (CMS), and the European Quality of Life 5 Dimensions (EQ-5D, rate your health today). Differences were determined before and after the intervention using the paired t test. Results: Significant differences (p < 0.05) were found in the results of all the questionnaires for the women with BC and for the healthy women: DASH (- 13.8 BC and - 6.7 healthy), CMS (+ 12.0 BC and 9.2 healthy), and EQ-5D (+ 8.5 BC and 10.5 healthy). Conclusion: Felucca rowing showed benefits in health and quality of life in both women with BC and healthy women. In future studies with controlled design, values regarding clinical relevance, such as effect sizes/confidence intervals, are needed to corroborate our results

Zepa beltzezko hormigoi armatuz fabrikatutako habeen makurdura-esfortzuaren aurreko analisia

Bizi garen mundua zaintzeko erronka dugu aurrean. Garapen jasangarrirako helburuak 2030 Agendan bildu dira, eta, 12. erronkari begira, "Kontsumo- eta ekoizpen-modalitate jasangarriak bermatzea", funtsezkoa da hondakinen kudeaketa lantzea. Altzairugintza-industria garrantzitsua da Euskal Herrian, ezinbestekoa ekonomiaren garapenerako. Horregatik, sektore horrek sortzen dituen hondakinei bizitza berri bat bilatzeko beharra dago. Hondakin nagusiak zepa beltzak dira eta eraikuntza-sektorean erabiltzen dira batik bat. Urte askotan, masa-hormigoietan agregakin bezala aztertu izan da zepa beltzaren portaera, eta oso emaitza onak lortu dira. Horregatik, lan honetan pauso bat aurrerago emango da, eta hormigoi armatuzko egiturak eraikitzeko aztertuko da zepa beltzaren erabilera. Laborategiko lan txikiak alde batera utzita, 600 l-ko bolumena egingo da, eraikuntza-prozedura arrunt batean edozein sendotasuneko zepa beltzez eginiko hormigoia nola fabrika daitekeen baieztatzeko. Lan honen erronka 4 m-ko hormigoi armatuzko habeak fabrikatzea da, makurduraren aurreko portaera aztertzeko. Erabiliko diren hormigoiak autotrinkotzaileak izango dira. Lortutako balio esperimentalak araudietan oinarritutako balio analitikoekin alderatu dira, eta emaitza onak lortu dira.; We are facing the challenge of preserving the world where we live. The sustainable development goals have been collected in agenda 2030. Taking into account the 12 goal “Assessing the modalities of sustainable consumption and production”, waste management is a process in which is mandatory to worked out. Iron and steel industry is an important industry in the Basque Country, necessary for the development of the economy. That 's why it 's important to look for a new life for the waste produced by this sector. For many years, the behavior of electric arc furnace slag has been studied as an aggregate in mass concrete. The results were very good. Therefore, a step further in this work will be taken, and the use of the electric arc furnace slag will be considered in the construction of reinforced concrete structures. Aside from small laboratory work, 600l mass will be made. To confirm how electric arc furnace slag concrete can be manufactured in a common construction procedure. The challenge with this work was to get self compacting concrete. On the other hand, 4m long reinforced concrete beams will be manufactured to analyze its bending behavior. The experimental values obtained have been compared to the analytical values, in accordance with the standards and the obtained results have been good

Melatonin Targets Metabolism in Head and Neck Cancer Cells by Regulating Mitochondrial Structure and Function

This study was funded by grants from the Ministerio de Economia, Industria y Competitividad y por el Fondo de Desarrollo Regional FEDER, Spain nº SAF2013-49019, SAF2017-85903-P, and from the Consejería de Innovación, Ciencia y Empresa, Junta de Andalucía (P07- CTS- 03135, P10- CTS- 5784, and CTS- 101), Spain. J.F. and L.M. have FPU fellowships from the Ministerio de Educación Cultura y Deporte, Spain. C.R.S. was a schorlarship holder from the Plan Propio de Investigación of the University of Granada.We wish to thank Michael O’Shea for proofreading the paper.Metabolic reprogramming, which is characteristic of cancer cells that rapidly adapt to the hypoxic microenvironment and is crucial for tumor growth and metastasis, is recognized as one of the major mechanisms underlying therapeutic resistance. Mitochondria, which are directly involved in metabolic reprogramming, are used to design novel mitochondria-targeted anticancer agents. Despite being targeted by melatonin, the functional role of mitochondria in melatonin's oncostatic activity remains unclear. In this study, we aim to investigate the role of melatonin in mitochondrial metabolism and its functional consequences in head and neck cancer. We analyzed the effects of melatonin on head and neck squamous cell carcinoma (HNSCC) cell lines (Cal-27 and SCC-9), which were treated with 100, 500, and 1500 mu M of melatonin for 1, 3, and 5 days, and found a connection between a change of metabolism following melatonin treatment and its effects on mitochondria. Our results demonstrate that melatonin induces a shift to an aerobic mitochondrial metabolism that is associated with changes in mitochondrial morphology, function, fusion, and fission in HNSCC. We found that melatonin increases oxidative phosphorylation (OXPHOS) and inhibits glycolysis in HNSCC, resulting in increased ROS production, apoptosis, and mitophagy, and decreased cell proliferation. Our findings highlight new molecular pathways involved in melatonin's oncostatic activity, suggesting that it could act as an adjuvant agent in a potential therapy for cancer patients. We also found that high doses of melatonin, such as those used in this study for its cytotoxic impact on HNSCC cells, might lead to additional effects through melatonin receptors.Ministerio de Economia, Industria y Competitividad y por el Fondo de Desarrollo Regional FEDER, Spain SAF2013-49019 SAF2017-85903-PJunta de Andalucia P07-CTS-03135 P10-CTS-5784 CTS-101Ministerio de Educacion Cultura y Deporte, SpainPlan Propio de Investigacion of the University of Granad

Registro paleoclimático del Pleistoceno Medio en el valle del rio Tajo.

The central region of the Iberian Peninsula has specific climatic characteristics that have affected the vegetation evolution along the Quaternary period. The scarce available paleoclimatic information has shown that the vegetation evolution did not follow the valid patterns for other regions, not only those for Europe regions but also those for other regions into the Iberian Peninsula. We present in this work three palynological records from alluvial deposits of the river Tajo that correspond, by datation and/or correlation with other well-dated deposits, to the Middle Pleistocene. The vegetation during this period was open mediterranean formations made up of mainly evergreen Quercus, Olea, Juniperus and Cistaceae, indicating the existence of a dry mediterranean climate. The vegetation evolution along the Middle Pleistocene, reconstructed from the three palynological records, also shows the development of more humid or more arid pulses into a general trend of increasing aridity during the Middle Pleistocene

Etología. Introducción a la ciencia del comportamiento

1ª ed., 3ª reimp.El objetivo de este libro es proporcionar una introducción a la Etología. Ésta ciencia responde al interés por profundizar en el conocimiento de las costumbres animales; por comprender la variedad de comportamientos que en diferentes situaciones exhiben los individuos de diferentes especies. Una posible definición de Etología podría ser: el estudio científico del comportamiento de los seres vivos. A lo largo de esta obra se analizan todos los aspectos que tienen que ver con el comportamiento animal, desde las causas y mecanismos de actuación o la adaptación y evolución y el bienestar animal.The purpose of this book is to provide an introduction to Ethology. This science responds to the interest in deepening the knowledge of animal customs; to understand the variety of behaviour that in different situations exhibit individuals of different species. A possible definition of ethology could be: the scientific study of the behavior of living beings. Throughout this book all aspects related to animal behavior, from the causes and mechanisms of action or adaptation and evolution and animal welfare, are analyzed