A meta-synthesis about the study of men's sexual behavior through the lens of hegemonic masculinity

The aim of this study is to understand how men experience sexual behavior in relation to dominant masculine norms in heteronormative social organizations. After a systematic search and a careful study selection process, we analyzed 15 scientific qualitative studies on men's sexual practices that draw on hegemonic masculinity. We then carried out a thematic synthesis of the results that collectively covered 438 male narratives ranging in age from 11 to 71. The results include (hetero)sex as a signifier of manhood, male sexual collectivity; sexual hierarchies; sexual risk; and the invisibility of sexual diversity. This meta- synthesis emphasizes the complex relationship between male sexuality and the influence of hegemonic masculinity, revealing important health and well-being effects on men. Also, this highlights a dynamic relationship that affects not only men but also their partners in sexual relationships.O objetivo deste estudo é compreender o modo como os homens experienciam o comportamento sexual em relação com as normas da masculinidade e de uma organização social heteronormativa. Após uma pesquisa sistemática e um detalhado processo de seleção, analisámos 15 estudos qualitativos sobre práticas sexuais masculinas e que se baseiam na teoria da masculinidade hegemónica. Depois, realizámos uma síntese temática dos resultados que coletivamente contemplam 438 narrativas de homens com idades entre os 11 e os 71 anos. Os resultados incluem sexo(hetero) como significante da masculinidade; coletividade sexual masculina; hierarquias sexuais; risco sexual; e invisibilidade da diversidade sexual. Esta meta-síntese enfatiza a complexa relação entre a sexualidade masculina e a influência da masculinidade hegemónica, revelando importantes efeitos ao nível da saúde e do bem-estar nos homens. Além disso, destaca uma relação dinâmica que afeta não apenas os homens, mas também as/os seus/suas parceiras/os nas relações sexuais.info:eu-repo/semantics/publishedVersio

Informação sobre o risco cambial: o caso de grandes empresas

Trabalho apresentado XXIII Jornadas Hispano Lusas de Gestão Cientifica, 7-9 fevereiro 2013, Málaga, EspanhaNo contexto de crise económica e financeira em que vivemos atualmente, cada vez mais as empresas recorrem aos mercados externos, enfrentando, com frequência, uma exposição significativa à volatilidade das divisas em que as suas operações são denominadas. É objetivo deste estudo verificar as práticas de divulgação de informação sobre o risco cambial e a sua gestão por empresas marcadamente expostas a este tipo de risco. Especificamente pretende-se verificar se as empresas apresentam informação relacionada com a política de gestão do risco cambial adotada, com os instrumentos usados nessa gestão e a conformidade da divulgação com o normativo aplicável. Verificamos que as empresas selecionadas podem constituir uma referência pois, de facto, gerem o risco cambial e divulgam informação sobre esta questão, em conformidade com as normas do IASB. Além de que a gestão efetuada produziu, em geral, no período considerado, resultados positivos.N/

Dystrophic calcinosis cutis associated with systemic lupus erythematosus: a case report

Calcinosis cutis is a rare and potentially disabling condition characterized by calcium deposition in soft tissues. When associated with autoimmune connective tissue diseases, calcinosis cutis is classified as Dystrophic Calcinosis Cutis (DCC), being its occurrence in systemic lupus erythematosus (SLE) patients fairly uncommon. We report a case of DCC in a 49 years old woman with eleven years evolution SLE that presented with a two years history of multiple painful skin lesions, some of them ulcerated and exhibiting a chalky white-yellow floor, in both hands, forearms, thighs, buttocks, abdomen and left breast. The pelvic X-ray showed soft tissue calcifications and the skin biopsy confirmed the diagnosis of DCC. The patient was treated with diltiazem 240mg/day and a significant regression of the lesions and associated pain was observed. Dystrophic calcinosis cutis is often a painful and disrupting condition in which timely diagnosis and treatment may be quite challenging

Exploring new pathways in endocrine-resistant breast cancer

Copyright: © The Author(s) 2022. This is an Open Access article licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The most common breast cancer (BC) subtypes are hormone-dependent, being either estrogen receptor-positive (ER+), progesterone receptor-positive (PR+), or both, and altogether comprise the luminal subtype. The mainstay of treatment for luminal BC is endocrine therapy (ET), which includes several agents that act either directly targeting ER action or suppressing estrogen production. Over the years, ET has proven efficacy in reducing mortality and improving clinical outcomes in metastatic and nonmetastatic BC. However, the development of ET resistance promotes cancer survival and progression and hinders the use of endocrine agents. Several mechanisms implicated in endocrine resistance have now been extensively studied. Based on the current clinical and pre-clinical data, the present article briefly reviews the well-established pathways of ET resistance and continues by focusing on the three most recently uncovered pathways, which may mediate resistance to ET, namely receptor activator of nuclear factor kappa B ligand (RANKL)/receptor activator of nuclear factor kappa B (RANK), nuclear factor kappa B (NFκB), and Notch. It additionally overviews the evidence underlying the approval of combined therapies to overcome ET resistance in BC, while highlighting the relevance of future studies focusing on putative mediators of ET resistance to uncover new therapeutic options for the disease.info:eu-repo/semantics/publishedVersio

Internações por condições sensíveis à atenção primária, Minas Gerais, 2000 e 2010

OBJECTIVE To analyze hospitalization rates and the proportion of deaths due to ambulatory care-sensitive hospitalizations and to characterize them according to coverage by the Family Health Strategy, a primary health care guidance program. METHODS An ecological study comprising 853 municipalities in the state of Minas Gerais, under the purview of 28 regional health care units, was conducted. We used data from the Hospital Information System of the Brazilian Unified Health System. Ambulatory care-sensitive hospitalizations in 2000 and 2010 were compared. Population data were obtained from the demographic censuses. RESULTS The number of ambulatory care-sensitive hospitalizations declined from 20.75/1,000 inhabitants [standard deviation (SD) = 10.42) in 2000 to 14.92/thousand inhabitants (SD = 10.04) in 2010 Heart failure was the most frequent cause in both years. Hospitalizations rates for hypertension, asthma, and diabetes mellitus, decreased, whereas those for angina pectoris, prenatal and birth disorders, kidney and urinary tract infections, and other acute infections increased. Hospitalization durations and the proportion of deaths due to ambulatory care-sensitive hospitalizations increased significantly. CONCLUSIONS Mean hospitalization rates for sensitive conditions were significantly lower in 2010 than in 2000, but no correlation was found with regard to the expansion of the population coverage of the Family Health Strategy. Hospitalization rates and proportion of deaths were different between the various health care regions in the years evaluated, indicating a need to prioritize the primary health care with high efficiency and quality.OBJETIVO Analisar taxas de permanência hospitalar e de proporção de óbitos por internações por condições sensíveis à atenção primária em saúde, caracterizando-as segundo cobertura pela Estratégia de Saúde da Família. MÉTODOS Trata-se de estudo ecológico que teve como unidade de análise os 853 municípios do estado de Minas Gerais, estratificados pelas 28 regionais de saúde. Foram utilizados dados do Sistema de Informação Hospitalar do Sistema Único de Saúde. As internações por condições sensíveis de 2000 foram comparadas às de 2010. Dados populacionais foram obtidos dos censos demográficos. RESULTADOS As internações por condições sensíveis à atenção primária apresentaram queda de 20,75/mil hab (DP = 10,42) em 2000 para 14,92/mil hab (DP = 10,04) em 2010. A insuficiência cardíaca foi a causa mais frequente em ambos os períodos. Houve redução nas taxas de internações por hipertensão arterial, asma e diabetes mellitus, bem como aumento nas internações por angina pectoris, doenças relacionadas ao pré-natal e parto, infecções de rim e trato urinário, além de outras infecções agudas. A permanência hospitalar e a proporção de óbitos por internações por condições sensíveis aumentaram significativamente. CONCLUSÕES A taxa média de internações por condições sensíveis foi significativamente menor em 2010 do que em 2000, mas não foi observada correlação com a expansão de cobertura populacional da Estratégia de Saúde da Família. As taxas de permanência hospitalar e proporção de óbitos entre os anos avaliados comportaram-se de forma distinta entre as diversas regionais de saúde, apontando necessidade de priorização de atenção primária resolutiva e de qualidade

The dualistic model of passion in adapted sport: a double-serial mediation analysis on satisfaction with life

Adapted sports practice has increased in recent years, and has now put an additional demand on research to further explore and understand the characteristics of this field of practice. The main aim of this study was to examine the serial mediation effects of motivation and affective activation in relationships between passion and satisfaction with life in adapted sports athletes. The study sample comprised 143 adapted sports athletes (male = 107) aged between 15 and 59 years (M = 29.21; SD = 10.45) enrolled in distinct modalities. Double serial mediation models were developed according to hypothetical associations, and were analyzed using PROCESS macro v. 3.3. In both models, no direct effect between the types of passion and satisfaction with life emerged. However, positive indirect effects through self-determined motivation have emerged in the harmonious and obsessive passion models, as for a distinct and positive effect of relatedness in satisfaction with lifeinfo:eu-repo/semantics/publishedVersio

Anais do VI SIMELP – Da união à diversidade

"No VI Simpósio Mundial de Estudos da Língua Portuguesa (SIMELP) “Da união à diversidade”, que teve lugar na Escola Superior de Educação do Instituto Politécnico de Santarém, pretendeu-se proporcionar um espaço aglutinador de discussões entre professores, pesquisadores, estudantes, em áreas como a linguística, a literatura, a cultura, a tradução, a educação, e, ainda, profissionais de outras áreas para quem a língua portuguesa se traduziu num ponto de interesse"info:eu-repo/semantics/publishedVersio

Knowledge and practices of community pharmacists in topical dermatological treatments

The connection between pharmacists’ knowledge and practice on the provided information to patients about dermatoses and their treatment is insufficiently characterized. Furthermore, pharmacists’ contributions in counselling and in promoting adherence to topical treatment is not fully understood. This study has three main objectives. It aims to identify the knowledge and practices of pharmacists about dermatoses and their treatment, and to compare the perspective of pharmacists with that of patients regarding treatment information, with the future goal of establishing guidelines on the communication of dosage regimen instructions to dermatological patients and promotion of adherence to treatment, filling a gap. A cross-sectional, exploratory, and descriptive study was carried out. Based on experts’ prior knowledge and extensive collected literature information, two questionnaire protocols, one for pharmacists and another one for patients, were designed. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were carried out in relation to the pharmacists’ questionnaire for instrument validation. The results indicate that knowledge of pharmacists regarding dermatoses and their treatment is considered acceptable. Most of the pharmacists were reported to provide information to patients. Oppositely, patients reported not to have receive it. This is an important issue because pharmacists play a primary role in the management of several diseases. As non-adherence can be triggered by poor understanding of the dosing instructions, pharmacists’ communication practices play an important role in improving this hinderance. Results from this study identified pharmacist–patient communication gaps, so the development of guidelines to improve the transmission of clear dosage regimen instructions and knowledge about patient’s disease are of paramount importance. Training programs for continuous education of pharmacist should be implemented to solve the identified communication problems found in this study.info:eu-repo/semantics/publishedVersio