60 research outputs found

    Contato fílmico: relaçÔes tåteis no cinema argentino contemporùneo

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    Este trabalho tem como objetivo investigar como as imagens cinematogrĂĄficas reverberam no corpo, as tentativas de definir suas medidas e seus limites no contato entre o filme e o espectador promovido pela experiĂȘncia cinematogrĂĄfica. A capacidade do filme de tocar, emular as sensaçÔes em nosso corpo revela como ele tambĂ©m Ă© um ser perceptivo e expressivo, com capacidade de movimento e tatilidade. E, a partir disso, procurar essas experiĂȘncias corporais no cinema argentino recente, com comentĂĄrios sobre os filmes Jauja e O auge do humano (El auge del humano)

    Comparison of Cognitive Performance between Elderly Training Practices with Weights and Sedentaria

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    Comparison of cognitive performance among elderly people practicing training with weights and sedentary lifestyle. Estudy descriptive, cross-sectional and comparative, composition for 24 elderly between 60 and 70 years, divided into 2 groups, (G1) submitted to weight training and sedentary (G2). The G1 was submitted to 32 training sessions with traditional weight. Both groups were submitted to CogStateÂź computerized cognitive testing batteries. The data were not parametric, using the Kolmogorov-Smirnov test for the analysis of the dispersion curve and the Mann-Whitney test in the comparison of the cognitive performance variables. The results were performed with a significance level of 0.05 by the Statistical Package for the Social Sciences (SPSSÂź), version 16.0. The best cognitive performance was observed among the elderly practicing resistance exercises, as well as significant differences in the TRS and TRE variables. Elderly people who exercise with weights when compared with cognitive performance demonstrate results of the paradigms when compared to the elderly. With this, he concludes that weight training is effective in improving cognitive performance

    Trombose mesentĂ©rica: aspectos clĂ­nicos e manejo terapĂȘutico

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    A Isquemia MesentĂ©rica Aguda (IMA) Ă© uma patologia que, devido a interrupção sĂșbita do fluxo sanguĂ­neo oxigenado para o intestino delgado, leva a lesĂ”es isquĂȘmicas, reversĂ­veis ou irreversĂ­veis, dos segmentos intestinais. Quanto Ă  epidemiologia, a IMA atinge 1 a em 100.000 indivĂ­duos e possui maior prevalĂȘncia em homens e em pessoas com fatores de risco, como idade avançada, fatores que levam Ă  lesĂŁo endotelial vascular, trombofilias e estase sanguĂ­nea. Acerca das manifestaçÔes clĂ­nicas, a doença apresenta dor abdominal intensa e sĂșbita, mas tambĂ©m pode estar associada a sintomas inespecĂ­ficos como nĂĄuseas, vĂŽmitos e/ou diarreia. Sua identificação depende de uma anamnese minuciosa, um exame fĂ­sico bem detalhado e exames complementares. No que tange ao diagnĂłstico clĂ­nico, o reconhecimento de fatores predisponentes da doença e um exame fĂ­sico acurado sĂŁo essenciais para identificação da patologia. Para diagnĂłstico definitivo, lança-se mĂŁo da Angiotomografia Computadorizada (ATC), ferramenta diagnĂłstica de escolha na suspeita de IMA, angiografia por cateter, radiografia simples e Ultrassonografia (US) de abdome, Tomografia Computadorizada (TC) e a RessonĂąncia Nuclear MagnĂ©tica (RNM), fornecendo mais detalhes com melhor acurĂĄcia para, juntamente com os dados clĂ­nicos, obter o diagnĂłstico. JĂĄ a abordagem terapĂȘutica, apresenta-se atravĂ©s do manejo farmacolĂłgico e cirĂșrgico. Na abordagem farmacolĂłgica, lança-se mĂŁo da suplementação com oxigĂȘnio e reidratação adequada com infusĂŁo de soro cristalĂłide, agentes vasoconstritores, heparina e antagonistas da vitamina K. A abordagem cirĂșrgica utiliza laparotomia primĂĄria, laparotomia planejada, embolectomia aberta, restauração do vaso afetado, podendo ser por bypass ou enxerto e opçÔes de tĂ©cnicas endovasculares de tratamento

    A IMPORTÂNCIA DO LEITE MATERNO PARA O CRESCIMENTO E DESENVOLVIMENTO INFANTIL

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    To analyze the importance of breast milk for infant growth and development using scientific evidence. Methods: This is a qualitative integrative literature review. The search for studies involved in the research was carried out in the following databases: SCIELO, LILACS, BDENF and MEDLINE, using the health sciences descriptors: "Breastfeeding", "Health promotion" and "Child health". The inclusion criteria were: published between 2014 and 2024, with free access to full texts, articles in Portuguese, English and Spanish and related to the theme. Exclusion criteria were: duplicate articles, incomplete articles, abstracts, reviews, debates, articles published in event proceedings and unavailable in full. Results: Through breastfeeding, physical well-being can be established, where the child feels cozy, in addition to this feeling of protection and skin-to-skin contact, this practice has a very positive impact. Conclusion: It can be concluded that breastfeeding is important for the child's development, especially in the first six months of life. It also provides the right nutrients in the right quantities for the child.Analisar por meio das evidĂȘncias cientificas a importĂąncia do leite materno para o crescimento e desenvolvimento infantil. MĂ©todos: Trata-se de uma revisĂŁo integrativa da literatura de carĂĄter qualitativo. A busca dos trabalhos envolvidos na pesquisa foi realizada nas seguintes bases de dados: SCIELO, LILACS, BDENF e MEDLINE, a partir dos descritores em ciĂȘncias da saĂșde: “Aleitamento materno”, “Promoção da saĂșde” e “SaĂșde da criança”. Os critĂ©rios de inclusĂŁo foram: publicados no perĂ­odo entre 2014 e 2024, cujo acesso ao periĂłdico era livre aos textos completos, artigos em idioma portuguĂȘs, inglĂȘs e espanhol e relacionados a temĂĄtica. CritĂ©rios de exclusĂŁo foram: artigos duplicados, incompletos, resumos, resenhas, debates, artigos publicados em anais de eventos e indisponĂ­veis na Ă­ntegra. Resultados: Por meio da amamentação pode se estabelecer o bem estar fĂ­sico, onde a criança se sente aconchegado, alĂ©m dessa sensação de proteção e contato pele a pele, essa prĂĄtica exercer um impacto bastante positivo. ConclusĂŁo: Conclui-se que a prĂĄtica do aleitamento materno Ă© importante para o desenvolvimento da criança principalmente nos primeiros seis meses de vida. AlĂ©m disso, ele possui os nutrientes corretos e em quantidades certas para a criança

    IAPT chromosome data 40

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    Pervasive gaps in Amazonian ecological research

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    Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

    Pervasive gaps in Amazonian ecological research

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    COMPLICAÇÕES DA DERIVAÇÃO VENTRÍCULO-PERITONEAL EM PACIENTES PEDIÁTRICOS: UMA REVISÃO INTEGRATIVA

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    Introduction: Hydrocephalus is characterized by the accumulation of cerebrospinal fluid (CSF) in the cerebral ventricular system, leading to increased intracranial pressure and dilatation of the ventricles. In children, it is manifested by irritability, accelerated growth of the head circumference, and signs of intracranial hypertension. Ventriculoperitoneal shunt (PVD) is a common surgical technique for CSF drainage. Objective: To analyze the complications associated with PVD in pediatric patients, identifying risk factors, patterns of occurrence, and clinical outcomes, to improve care and clinical outcomes. Methodology: An integrative review was carried out in consultation with PubMed and SciELO. Descriptors such as "ventriculoperitoneal shunt," "complications," "hydrocephalus," "infection," and "malfunction" were used. Articles from the last five years, in Portuguese and English, addressing complications of PVD were included. Out-of-scope, full-text, and duplicate studies were excluded. A total of 11 articles were selected for analysis. Results: We included 11 articles that highlighted complications such as infections, device malfunctions, obstructions, and abdominal complications. Shunt infections occur in up to 15% of pediatric cases, often within the first 6 to 12 months postoperatively. Distal catheter malfunction is common and requires frequent surgical revisions. Rare complications include abdominal pseudocysts, distal catheter extrusion, and gram-negative bacterial infections, with high rates in the first few days after shunt insertion. Frequent revisions increase the risk of complications. Conclusions: PVD, although effective, has several complications that impact the quality of life of pediatric patients. Infections and system malfunctions are the most common complications. Multidisciplinary management and preventive strategies are essential to optimize clinical outcomes and quality of life for patients.IntroducciĂłn: La hidrocefalia se caracteriza por la acumulaciĂłn de lĂ­quido cefalorraquĂ­deo (LCR) en el sistema ventricular cerebral, lo que conduce a un aumento de la presiĂłn intracraneal y a la dilataciĂłn de los ventrĂ­culos. En los niños, se manifiesta por irritabilidad, crecimiento acelerado de la circunferencia cefĂĄlica y signos de hipertensiĂłn intracraneal. La derivaciĂłn ventriculoperitoneal (PVD, por sus siglas en inglĂ©s) es una tĂ©cnica quirĂșrgica comĂșn para el drenaje del LCR. Objetivo: Analizar las complicaciones asociadas a la EVP en pacientes pediĂĄtricos, identificando factores de riesgo, patrones de ocurrencia y resultados clĂ­nicos, para mejorar la atenciĂłn y los resultados clĂ­nicos. MetodologĂ­a: Se realizĂł una revisiĂłn integradora en consulta con PubMed y SciELO. Se utilizaron descriptores como "derivaciĂłn ventriculoperitoneal", "complicaciones", "hidrocefalia", "infecciĂłn" y "disfunciĂłn". Se incluyeron artĂ­culos de los Ășltimos cinco años, en portuguĂ©s e inglĂ©s, que abordaron las complicaciones de la EVP. Se excluyeron los estudios fuera de alcance, de texto completo y duplicados. Se seleccionaron un total de 11 artĂ­culos para el anĂĄlisis. Resultados: Se incluyeron 11 artĂ­culos que destacaron complicaciones como infecciones, mal funcionamiento del dispositivo, obstrucciones y complicaciones abdominales. Las infecciones por derivaciĂłn ocurren hasta en el 15% de los casos pediĂĄtricos, a menudo dentro de los primeros 6 a 12 meses despuĂ©s de la operaciĂłn. El mal funcionamiento del catĂ©ter distal es comĂșn y requiere revisiones quirĂșrgicas frecuentes. Las complicaciones raras incluyen pseudoquistes abdominales, extrusiĂłn de catĂ©ter distal e infecciones bacterianas gramnegativas, con tasas altas en los primeros dĂ­as despuĂ©s de la inserciĂłn de la derivaciĂłn. Las revisiones frecuentes aumentan el riesgo de complicaciones. Conclusiones: La EVP, aunque efectiva, tiene varias complicaciones que impactan en la calidad de vida de los pacientes pediĂĄtricos. Las infecciones y el mal funcionamiento del sistema son las complicaciones mĂĄs comunes. El manejo multidisciplinario y las estrategias preventivas son esenciales para optimizar los resultados clĂ­nicos y la calidad de vida de los pacientes.Introdução: A hidrocefalia Ă© caracterizada pelo acĂșmulo de lĂ­quido cefalorraquidiano (LCR) no sistema ventricular cerebral, levando ao aumento da pressĂŁo intracraniana e dilatação dos ventrĂ­culos. Em crianças, manifesta-se por irritabilidade, crescimento acelerado do perĂ­metro cefĂĄlico e sinais de hipertensĂŁo intracraniana. A derivação ventrĂ­culo-peritoneal (DVP) Ă© uma tĂ©cnica cirĂșrgica comum para drenagem do LCR. Objetivo: Analisar as complicaçÔes associadas Ă  DVP em pacientes pediĂĄtricos, identificando fatores de risco, padrĂ”es de ocorrĂȘncia e desfechos clĂ­nicos, para melhorar os cuidados e resultados clĂ­nicos. Metodologia: Realizou-se uma revisĂŁo integrativa consultando PubMed e SciELO. Utilizaram-se descritores como "ventriculoperitoneal shunt," "complications," "hydrocephalus," "infection," e "malfunction". Foram incluĂ­dos artigos dos Ășltimos cinco anos, em portuguĂȘs e inglĂȘs, abordando complicaçÔes da DVP. ExcluĂ­ram-se estudos fora do escopo, nĂŁo disponĂ­veis em texto completo e duplicados. Selecionaram-se 11 artigos para anĂĄlise. Resultados: Foram integrados 11 artigos que destacaram complicaçÔes como infecçÔes, mau funcionamento do dispositivo, obstruçÔes e complicaçÔes abdominais. InfecçÔes de shunt ocorrem em atĂ© 15% dos casos pediĂĄtricos, frequentemente nos primeiros 6 a 12 meses pĂłs-cirurgia. O mau funcionamento do cateter distal Ă© comum e requer revisĂ”es cirĂșrgicas frequentes. ComplicaçÔes raras incluem pseudocistos abdominais, extrusĂŁo distal do cateter e infecçÔes bacterianas gram-negativas, com altas taxas nos primeiros dias apĂłs a inserção do shunt. RevisĂ”es frequentes aumentam o risco de complicaçÔes. ConclusĂ”es: A DVP, embora eficaz, apresenta vĂĄrias complicaçÔes que impactam a qualidade de vida dos pacientes pediĂĄtricos. InfecçÔes e mau funcionamento do sistema sĂŁo as complicaçÔes mais comuns. A gestĂŁo multidisciplinar e estratĂ©gias preventivas sĂŁo essenciais para otimizar os resultados clĂ­nicos e a qualidade de vida dos pacientes

    Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

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    Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period. Methods: 22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, antenatal clinic serosurveillance, and other data sources. Excess mortality due to the COVID-19 pandemic in 2020 and 2021 was determined by subtracting observed all-cause mortality (adjusted for late registration and mortality anomalies) from the mortality expected in the absence of the pandemic. Expected mortality was calculated based on historical trends using an ensemble of models. In location-years where all-cause mortality data were unavailable, we estimated excess mortality rates using a regression model with covariates pertaining to the pandemic. Population size was computed using a Bayesian hierarchical cohort component model. Life expectancy was calculated using age-specific mortality rates and standard demographic methods. Uncertainty intervals (UIs) were calculated for every metric using the 25th and 975th ordered values from a 1000-draw posterior distribution. Findings: Global all-cause mortality followed two distinct patterns over the study period: age-standardised mortality rates declined between 1950 and 2019 (a 62·8% [95% UI 60·5–65·1] decline), and increased during the COVID-19 pandemic period (2020–21; 5·1% [0·9–9·6] increase). In contrast with the overall reverse in mortality trends during the pandemic period, child mortality continued to decline, with 4·66 million (3·98–5·50) global deaths in children younger than 5 years in 2021 compared with 5·21 million (4·50–6·01) in 2019. An estimated 131 million (126–137) people died globally from all causes in 2020 and 2021 combined, of which 15·9 million (14·7–17·2) were due to the COVID-19 pandemic (measured by excess mortality, which includes deaths directly due to SARS-CoV-2 infection and those indirectly due to other social, economic, or behavioural changes associated with the pandemic). Excess mortality rates exceeded 150 deaths per 100 000 population during at least one year of the pandemic in 80 countries and territories, whereas 20 nations had a negative excess mortality rate in 2020 or 2021, indicating that all-cause mortality in these countries was lower during the pandemic than expected based on historical trends. Between 1950 and 2021, global life expectancy at birth increased by 22·7 years (20·8–24·8), from 49·0 years (46·7–51·3) to 71·7 years (70·9–72·5). Global life expectancy at birth declined by 1·6 years (1·0–2·2) between 2019 and 2021, reversing historical trends. An increase in life expectancy was only observed in 32 (15·7%) of 204 countries and territories between 2019 and 2021. The global population reached 7·89 billion (7·67–8·13) people in 2021, by which time 56 of 204 countries and territories had peaked and subsequently populations have declined. The largest proportion of population growth between 2020 and 2021 was in sub-Saharan Africa (39·5% [28·4–52·7]) and south Asia (26·3% [9·0–44·7]). From 2000 to 2021, the ratio of the population aged 65 years and older to the population aged younger than 15 years increased in 188 (92·2%) of 204 nations. Interpretation: Global adult mortality rates markedly increased during the COVID-19 pandemic in 2020 and 2021, reversing past decreasing trends, while child mortality rates continued to decline, albeit more slowly than in earlier years. Although COVID-19 had a substantial impact on many demographic indicators during the first 2 years of the pandemic, overall global health progress over the 72 years evaluated has been profound, with considerable improvements in mortality and life expectancy. Additionally, we observed a deceleration of global population growth since 2017, despite steady or increasing growth in lower-income countries, combined with a continued global shift of population age structures towards older ages. These demographic changes will likely present future challenges to health systems, economies, and societies. The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better understand and address the profound changes that have occurred in the global health landscape following the first 2 years of the COVID-19 pandemic, and longer-term trends beyond the pandemic

    Pervasive gaps in Amazonian ecological research

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    Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost
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