Basic Phytotherapy and Podiatry

Este trabajo pretende ofrecer una serie de conocimientos o premisas básicas sobre la Fitoterapia y como su uso nos puede ser de ayuda en Podología. Presentamos una serie de conclusiones sobre las plantas medicinales y su farmacología, así como los principios activos más importantes, los grupos en que se divide…etc. No Obstante, hablamos de las realidades fundamentales de la fitoterapia sin despreciar la Medicina Tradicional, y por supuesto, también hablamos de los inconvenientes que tiene. Intentamos aplicar la Fitoterapia a la Podología mostrando aquí una pequeña, mínima, serie de plantas medicinales que nos pueden ser de utilidad, una forma de pequeño compendio que nos muestra sus propiedades. Luego aplicamos éstos conocimientos a determinadas patologías muy frecuentes en el pie como la gota, esguinces, verrugas…etc. Y para finalizar, algunos remedios caseros y las conclusiones.This work tries to offer a series of knowledge or basic premises on the fitotherapy and as its use can help us in chiropody. We present a series of conclusions on the medicinal plants and their pharmacology, as well as the most important active elements, the groups in that is divided…Despite, we speak of the fundamental realities of the fitotherapy without despising the traditional medicine, and by all means, also we speak of the disadvantages that it has. We try to apply the fitotherapy to the chiropody, showing here a small, minimum series of medicinal plants that can come in useful, a form of small compendium that shows its properties to us. Then, we applied these knowledges to certain very frequent pathologies in the foot, as the disease in the smaller bones of the ffetgout-, the sprains-wrench or twist the ligaments of an ankle violently, warts- small bening qrowth on the skin. And to finalize, some domestic remedies and the conclusions

Retrograde Approach for Endovascular Salvage of an Infrapopliteal Vein Bypass

Producción CientíficaEndovascular treatment through femoropopliteal and infragenicular percutaneous transluminal angioplasty, both in native vessels and in bypass salvage, has been an emerging technique in recent years. However, in some cases, a difficult anterograde access in distal occlusions has limited the technical success of this procedure. Combined subintimal arterial flossing with antegradeeretrograde intervention is used as a resource technique to obtain precise recanalization in these cases. Here, we present the case of a retromalleolar access of the posterior tibial artery, based on subintimal arterial flossing with antegradeeretrograde intervention technique, to achieve femoraleposterior tibial bypass salvage

Humoral and Cellular Immune Responses After a 3-dose Course of mRNA-1273 COVID-19 Vaccine in Kidney Transplant Recipients: A Prospective Cohort Study.

In kidney transplant recipients, there is discordance between the development of cellular and humoral response after vaccination against SARS-CoV-2. We sought to determine the interplay between the 2 arms of adaptive immunity in a 3-dose course of mRNA-1273 100 μg vaccine. Methods: Humoral (IgG/IgM) and cellular (N- and S-ELISpot) responses were studied in 117 kidney and 12 kidney-pancreas transplant recipients at the following time points: before the first dose, 14 d after the second dose' and before and after the third dose, with a median of 203 and 232 d after the start of the vaccination cycle, respectively. Results: After the second dose, 26.7% of naive cases experienced seroconversion. Before the third dose and in the absence of COVID-19, this percentage increased to 61.9%. After the third dose, seroconversion occurred in 80.0% of patients. Naive patients who had at any time point a detectable positivity for S-ELISpot were 75.2% of the population, whereas patients who maintained S-ELISpot positivity throughout the study were 34.3%. S-ELISpot positivity at 42 d was associated with final seroconversion (odds ratio' 3.14; 95% confidence interval' 1.10-8.96; P = 0.032). Final IgG titer was significantly higher in patients with constant S-ELISpot positivity (P < 0.001). Conclusions: A substantial proportion of kidney transplant recipients developed late seroconversion after 2 doses. Cellular immunity was associated with the development of a stronger humoral respons

The striking geographical pattern of gastric cancer mortality in Spain: environmental hypotheses revisited

<p>Abstract</p> <p>Background</p> <p>Gastric cancer is decreasing in most countries. While socioeconomic development is the main factor to which this decline has been attributed, enormous differences among countries and within regions are still observed, with the main contributing factors remaining elusive. This study describes the geographic distribution of gastric cancer mortality at a municipal level in Spain, from 1994-2003.</p> <p>Methods</p> <p>Smoothed relative risks of stomach cancer mortality were obtained, using the Besag-York-Molliè autoregressive spatial model. Maps depicting relative risk (RR) estimates and posterior probabilities of RR being greater than 1 were plotted.</p> <p>Results</p> <p>From 1994-2003, 62184 gastric cancer deaths were registered in Spain (7 percent of all deaths due to malignant tumors). The geographic pattern was similar for both sexes. RRs displayed a south-north and coast-inland gradient, with lower risks being observed in Andalusia, the Mediterranean coastline, the Balearic and Canary Islands and the Cantabrian seaboard. The highest risk was concentrated along the west coast of Galicia, broad areas of the Castile & Leon Autonomous community, the province of Cáceres in Extremadura, Lleida and other areas of Catalonia.</p> <p>Conclusion</p> <p>In Spain, risk of gastric cancer mortality displays a striking geographic distribution. With some differences, this persistent and unique pattern is similar across the sexes, suggesting the implication of environmental exposures from sources, such as diet or ground water, which could affect both sexes and delimited geographic areas. Also, the higher sex-ratios found in some areas with high risk of smoking-related cancer mortality in males support the role of tobacco in gastric cancer etiology.</p

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Suitability study of structure-from-motion for the digitisation of architectural (Heritage) spaces to apply divergent photograph collection

The digitisation of architectural heritage has experienced a great development of low-cost and high-definition data capture technologies, thus enabling the accurate and effective modelling of complex heritage assets. Accordingly, research has identified the best methods to survey historic buildings, but the suitability of Structure-from-Motion/Multi-view-Stereo (SfM/MVS) for interior square symmetrical architectural spaces is unexplored. In contrast to the traditional SfM surveying for which the camera surrounds the object, the photograph collection approach is divergent in courtyards. This paper evaluates the accuracy of SfM point clouds against Terrestrial Laser Scanning (TLS) for these large architectural spaces with a symmetrical configuration, with the main courtyard of Casa de Pilatos in Seville, Spain, as a case study. Two different SfM surveys were conducted: (1) Without control points, and (2) referenced using a total station. The first survey yielded unacceptable results: A standard deviation of 0.0576 m was achieved in the northwest sector of the case study, mainly because of the difficulty of aligning the SfM and TLS data due to the way they are produced. This value could be admissible depending on the purpose of the photogrammetric model.Universidad de Sevill

La educación para la salud del siglo XXI : comunicación y salud

El libro introduce al estudio de los grandes problemas que se perfilan para el siglo XXI que afectan a la Salud de los hombres y mujeres de toda edad y condición y que son, en gran medida, educativos. Resalta los rasgos y señas de identidad de esta generación y el papel que van a jugar las nuevas tecnologías y las estructuras mediáticas, tanto en el lenguaje, la comunicación y las relaciones humanas, como en la manera de aprender y enfermar de las generaciones que van surgiendo. Son campos obligados y novedades en un libro de estas características la Metodología de Investigación en Educación para la Salud: la recreación del método de trabajo -ver, juzgar, actuar- el marco teórico de la educación para la salud junto con los instrumentos, clave para su desarrollo en el siglo XXI, los grandes cambios socio sanitarios, el papel de la educación, el reto de la autoestima como caldo de cultivo del crecimiento de las personas sanas, la fuerza del trabajo en grupo y el dinamismo ético de una educación en valores.Castilla y LeónES