Fertilización nitrogenada con estiércol bovino en la producción de maíz

El maíz chipa (Zea mays L. subsp. amylacea Sturtev.) en Paraguay es un cultivo tradicional de la agricultura familiar. El bajo rendimiento nacional de este rubro, puede ser en parte corregido, con aplicaciones adecuadas de enmiendas orgánicas y nitrógeno. El experimento se realizó en el Distrito de Caaguazú, con el objetivo de evaluar el efecto de la aplicación de estiércol bovino y nitrógeno en el maíz chipa en siembra directa. Fue desarrollado en un diseño de bloques completamente al azar con disposición en parcelas divididas, donde el factor A que fue tres dosis de estiércol bovino (0, 7,5 y 15 t ha-1 ) ocuparon las parcelas y el factor B que consistió en 5 dosis de N (0, 40, 80, 120 y 160 kg ha-1 ) ocuparon las sub parcelas. Se contó con 15 tratamientos y 4 repeticiones totalizando 60 unidades experimentales, cada unidad experimental tuvo una dimensión de 5 m de largo y 3 m de ancho (15 m2 ). Se determinó variables de crecimiento y rendimiento en el maíz, siendo los datos sometidos a análisis de varianza, comparación de medias y análisis de regresión. La aplicación de estiércol bovino incremento los parámetros analizados a excepción de la población de plantas, aumentaron, en 0,79 m de altura del maíz, en 0,55 cm el diámetro del tallo, en 5,34 cm la longitud de la mazorca, en 0,95 cm el diámetro de la mazorca, en 48,67 g el peso mil semillas, en 2.534 kg ha-1 la masa seca aérea, en 3.102 kg ha-1 el rendimiento en granos, cuando comparado los resultados de mayor dosis de estiércol y el testigo. La aplicación de N aumento únicamente las variables, altura de la planta, diámetro del tallo y materia seca aérea. No se observó interacción entre los factores estudiados. El uso de estiércol bovino genera efecto favorable en variables de crecimiento y rendimiento del maíz; el N no incrementó variables del rendimiento del maíz.CONACYT – Consejo Nacional de Ciencia y TecnologíaPROCIENCI

Evaluation of organic and inorganic residues for organic production systems and small properties of Paraguay

The objective of this study was to evaluate the effect of organic and inorganic residues in the soil and agricultural products of the small property. Were evaluated doses of ash obtained from the soybean processing industry, doses of compost made from residues of the sugar industry and dose of bovine manure from the farm itself.CONACYT – Consejo Nacional de Ciencia y TecnologíaPROCIENCI

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyper-activity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette syndrome. Genetic correlation analyses revealed a meaningful structure within the eight disorders, identifying three groups of inter-related disorders. Meta-analysis across these eight disorders detected 109 loci associated with at least two psychiatric disorders, including 23 loci with pleiotropic effects on four or more disorders and 11 loci with antagonistic effects on multiple disorders. The pleiotropic loci are located within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes. These findings have important implications for psychiatric nosology, drug development, and risk prediction.Peer reviewe

Effective universality in quantum gravity

We investigate the asymptotic safety scenario for a scalar-gravity system. This system contains two avatars of the dynamical Newton coupling, a gravitational self-coupling and a scalar-graviton coupling. We uncover an effective universality for the dynamical Newton coupling on the quantum level: its momentum-dependent avatars are in remarkable quantitative agreement in the scaling regime of the UV fixed point. For the background Newton coupling, this effective universality is not present, but qualitative agreement remains

Universal gravitational-wave signatures from heavy new physics in the electroweak sector

We calculate the gravitational-wave spectra produced by the electroweak phase transition with TeV-scale Beyond-Standard-Model physics in the early universe. Our study captures the effect of quantum and thermal fluctuations within a non-perturbative framework. We discover a universal relation between the mean bubble separation and the strength parameter of the phase transition, which holds for a wide range of new-physics contributions. The ramifications of this result are three-fold: first, they constrain the gravitational-wave spectra resulting from heavy (TeV-scale) new physics. Second, they contribute to distinguishing heavy from light new physics directly from the gravitational-wave signature. Third, they suggest that a concerted effort of gravitational-wave observations together with collider experiments could be required to distinguish between different models of heavy new physics

Confronting existing knowledge on ecological preferences of stream macroinvertebrates with independent biomonitoring data using a Bayesian multi-species distribution model

Contains fulltext : 231389pub.pdf (publisher's version ) (Open Access

Recurrent necrotizing cellulitis, multi-organ autoimmune disease and humoral immunodeficiency due to a novel NFKB1 frameshift mutation

Background: Mutations in NFKB1(nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) are associated with a variety of clinical symptoms, including lymphadenopathy, splenomegaly, hepatomegaly, autoimmune haemolytic anaemia, arthralgia, recurrent respiratory tract infections and post-operative necrotizing cellulitis. Case presentation: We describe a case of a 47-year-old man, who presented with deep necrotizing cellulitis after incision of a submucous abscess by a dentist. Surgical intervention led to a massive progress. Pyoderma gangraenosum (PG) was diagnosed clinically and confirmed histopathologically. High dose corticosteroids and intravenous immunoglobulins (IVIG) improved wound healing dramatically. Until now, immune mediated inflammation events not only affected the skin, but also multiple inner organs, i.e. the heart, lungs and gut. Sequencing of all coding exons of NFKB1 revealed a heterozygous 1bp deletion in exon 23 predicting a frameshift starting at codon Ala891 and resulting in a subsequent stop codon at position 6 in the new reading frame: NM_003998.4: c.2671del; p.(Ala891Glnfs*6) Acute episodes were always successfully treated with corticosteroids, IVIG and concomitant antibiotics. To prevent further exacerbations, the patient receives IVIG once a month, low-dose corticosteroids and methotrexate. Conclusion: This is the first case of a patient with recurrent necrotizing cellulitis and immune mediated multi organ involvement (heart, lungs, intestine) carrying the novel frameshift mutation c.2671del (p. Ala891Glnfs*6) in NFKB1 effectively treated with IVIG, low-dose corticosteroids and methotrexate