Potential of the next generation VHE instruments to probe the EBL (I): the low- and mid-VHE

The diffuse meta-galactic radiation field at ultraviolet to infrared wavelengths - commonly labeled extragalactic background light (EBL) - contains the integrated emission history of the universe. Difficult to access via direct observations indirect constraints on its density can be derived through observations of very-high energy (VHE; E>100 GeV) gamma-rays from distant sources: the VHE photons are attenuated via pair-production with the low energy photons from the EBL, leaving a distinct imprint in the VHE spectra measured on earth. Discoveries made with current generation VHE observatories like H.E.S.S. and MAGIC enabled strong constraints on the density of the EBL especially in the near-infrared. In this article the prospect of future VHE observatories to derive new constraints on the EBL density are discussed. To this end, results from current generation instruments will be extrapolated to the future experiment's sensitivity and investigated for their power to enable new methods and improved constraints on the EBL density.Comment: Accepted for publication in Astroparticle Physics; v2: extended discussion following referees comments, conclusions unchange

Potential of EBL and cosmology studies with the Cherenkov Telescope Array

Very high energy (VHE, E >100 GeV) gamma-rays are absorbed via interaction with low-energy photons from the extragalactic background light (EBL) if the involved photon energies are above the threshold for electron-positron pair creation. The VHE gamma-ray absorption, which is energy dependent and increases strongly with redshift, distorts the VHE spectra observed from distant objects. The observed energy spectra of the AGNs carry, therefore, an imprint of the EBL. The detection of VHE gamma-ray spectra of distant sources (z = 0.11 - 0.54) by current generation Imaging Atmospheric Cherenkov Telescopes (IACTs) enabled to set strong upper limits on the EBL density, using certain basic assumptions about blazar physics. In this paper it is studied how the improved sensitivity of the Cherenkov Telescope Array (CTA) and its enlarged energy coverage will enlarge our knowledge about the EBL and its sources. CTA will deliver a large sample of AGN at different redshifts with detailed measured spectra. In addition, it will provide the exciting opportunity to use gamma ray bursts (GRBs) as probes for the EBL density at high redshifts.Comment: 12 pages, 9 figures, to appear in Astroparticle Physics. arXiv admin note: text overlap with arXiv:1005.119

Probing the peak of the star formation rate density with the extragalactic background light

The extragalactic background light (EBL), i.e., the diffuse meta-galactic photon field in the ultraviolet to infrared, is dominated by the emission from stars in galaxies. It is, therefore, intimately connected with the integrated star formation rate density (SFRD). In this paper, the SFRD is constrained using recent limits on the EBL density derived from observations of distant sources of high and very-high energy gamma-rays. The stellar EBL contribution is modeled utilizing simple stellar population spectra including dust attenuation and emission. For modeling the SFRD up to z=4 a broken power law function in z+1 is assumed. A wide range of values for the different model parameters (SFRD(z), metallicity, dust absorption) is investigated and their impact on the resulting EBL is studied. The calculated EBL densities are compared with the specific EBL density limits and constraints on the SFRD are derived. For the fiducial model, adopting a Chabrier initial mass function (IMF) and a second power law index for the SFRD of beta=0.3, the SFRD is constrained to <~ 0.1 M_solar yr^-1 Mpc^-3 and < 0.2 M_solar yr^-1 Mpc^-3 for a redshift of z~1 and z~2, respectively. The limits for a redshift of z~1 are in tension with SFRD measurements derived from instantaneous star formation tracers. While the tension for the conservative fiducial model in this study is not yet overly strong, the tension increases when applying plausible changes to the model parameters, e.g., using a Salpeter instead of a Chabrier IMF or a adopting a sub-solar metallicity.Comment: 10 pages, 12 figure, accepted for publication in MNRAS, v3: clarifications following referee's comments, conclusions unchange

The H.E.S.S. extragalactic sky

The H.E.S.S. Cherenkov telescope array, located on the southern hemisphere in Namibia, studies very high energy (VHE; E>100 GeV) gamma-ray emission from astrophysical objects. During its successful operations since 2002 more than 80 galactic and extra-galactic gamma-ray sources have been discovered. H.E.S.S. devotes over 400 hours of observation time per year to the observation of extra-galactic sources resulting in the discovery of several new sources, mostly AGNs, and in exciting physics results e.g. the discovery of very rapid variability during extreme flux outbursts of PKS 2155-304, stringent limits on the density of the extragalactic background light (EBL) in the near-infrared derived from the energy spectra of distant sources, or the discovery of short-term variability in the VHE emission from the radio galaxy M 87. With the recent launch of the Fermi satellite in 2008 new insights into the physics of AGNs at GeV energies emerged, leading to the discovery of several new extragalactic VHE sources. Multi-wavelength observations prove to be a powerful tool to investigate the production mechanism for VHE emission in AGNs. Here, new results from H.E.S.S. observations of extragalactic sources will be presented and their implications for the physics of these sources will be discussed.Comment: 8 pages, 6 figures, invited review talk, in the proceedings of the "International Workshop on Beamed and Unbeamed Gamma-Rays from Galaxies" 11-15 April 2011, Lapland Hotel Olos, Muonio, Finland, Journal of Physics: Conference Series Volume 355, 201

Investigating generalizability of results from a randomized controlled trial of the management of chronic widespread pain : the MUSICIAN study

The MUSICIAN trial was supported by an award from Arthritis Research UK, Chesterfield, UK. Grant number: 17292. Ethical approval for the study was granted by Cheshire NHS Research Ethics Committee; reference number: 07/Q1506/61. All participants provided written consent.Peer reviewedPublisher PD

Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range

Quantitative analysis of time-resolved data in primary erythroid progenitor cells reveals that a dual negative transcriptional feedback mechanism underlies the ability of STAT5 to respond to the broad spectrum of physiologically relevant Epo concentrations

Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma

The American Thyroid Association appointed a Task Force of experts to revise the original Medullary Thyroid Carcinoma: Management Guidelines of the American Thyroid Association

First detection of a VHE gamma-ray spectral maximum from a Cosmic source: H.E.S.S. discovery of the Vela X nebula

The Vela supernova remnant (SNR) is a complex region containing a number of sources of non-thermal radiation. The inner section of this SNR, within 2 degrees of the pulsar PSR B0833-45, has been observed by the H.E.S.S. gamma-ray atmospheric Cherenkov detector in 2004 and 2005. A strong signal is seen from an extended region to the south of the pulsar, within an integration region of radius 0.8 deg. around the position (RA = 08h 35m 00s, dec = -45 deg. 36' J2000.0). The excess coincides with a region of hard X-ray emission seen by the ROSAT and ASCA satellites. The observed energy spectrum of the source between 550 GeV and 65 TeV is well fit by a power law function with photon index = 1.45 +/- 0.09(stat) +/- 0.2(sys) and an exponential cutoff at an energy of 13.8 +/- 2.3(stat) +/- 4.1(sys) TeV. The integral flux above 1 TeV is (1.28 +/- 0.17 (stat) +/- 0.38(sys)) x 10^{-11} cm^{-2} s^{-1}. This result is the first clear measurement of a peak in the spectral energy distribution from a VHE gamma-ray source, likely related to inverse Compton emission. A fit of an Inverse Compton model to the H.E.S.S. spectral energy distribution gives a total energy in non-thermal electrons of ~2 x 10^{45} erg between 5 TeV and 100 TeV, assuming a distance of 290 parsec to the pulsar. The best fit electron power law index is 2.0, with a spectral break at 67 TeV.Comment: 5 pages, 4 figures, accepted for publication in Astronomy and Astrophysics letter

A possible association of the new VHE gamma-ray source HESS J1825--137 with the pulsar wind nebula G18.0--0.7

We report on a possible association of the recently discovered very high-energy $\gamma$-ray source HESS J1825--137 with the pulsar wind nebula (commonly referred to as G 18.0--0.7) of the $2.1\times 10^{4}$ year old Vela-like pulsar PSR B1823--13. HESS J1825--137 was detected with a significance of 8.1 $\sigma$ in the Galactic Plane survey conducted with the H.E.S.S. instrument in 2004. The centroid position of HESS J1825--137 is offset by 11\arcmin south of the pulsar position. \emph{XMM-Newton} observations have revealed X-ray synchrotron emission of an asymmetric pulsar wind nebula extending to the south of the pulsar. We argue that the observed morphology and TeV spectral index suggest that HESS J1825--137 and G 18.0--0.7 may be associated: the lifetime of TeV emitting electrons is expected to be longer compared to the {\it XMM-Newton} X-ray emitting electrons, resulting in electrons from earlier epochs (when the spin-down power was larger) contributing to the present TeV flux. These electrons are expected to be synchrotron cooled, which explains the observed photon index of $\sim 2.4$, and the longer lifetime of TeV emitting electrons naturally explains why the TeV nebula is larger than the X-ray size. Finally, supernova remnant expansion into an inhomogeneous medium is expected to create reverse shocks interacting at different times with the pulsar wind nebula, resulting in the offset X-ray and TeV $\gamma$-ray morphology.Comment: 5 pages, 3 figures, to appear in Astronomy and Astrophysics Letter