10 research outputs found
Ethnobotanique de la Nation crie d'Eeyou Istchee et variation géographique des plantes médicinales antidiabétiques
Le diabète de type 2 affecte en moyenne 29% de la population adulte crie d’Eeyou Istchee (CEI). Afin d’identifier les plantes médicinales possédant un potentiel antidiabétique, des interviews ont été réalisés dans les communautés CEI de Wemindji et Oujé-Bougoumou. Utilisant une approche quantitative, les espèces mentionnées ont été classées et comparées à la pharmacopée des communautés avoisinantes. Seize et 25 plantes ont été mentionné à Wemindji et Oujé-Bougoumou, respectivement. Sept nouvelles espèces de plantes et une de champignon se sont ajoutées à la liste des espèces à potentiel antidiabétique, bien que la plupart de celles mentionnées pendant les interviews soit en communes à la pharmacopée CEI générale, démontrant ainsi leur importance culturelle. Des analyses phytochimiques sur deux de ces espèces, Rhododendron groenlandicum et Sarracenia purpurea, ont été réalisées à partir d’échantillons récoltés à différents endroits du territoire eeyouch. Bien qu’aucun patron n’ait été détecté dans la variation des composantes biologiquement actives chez S. purpurea, les composés phénoliques chez R. groenlandicum, particulièrement la (+)-catéchine, l’(-)-epicatéchine et la quercétine-3-galactoside, varient spatialement en fonction de paramètres d’insolation telles la radiation solaire ou la photopériode. Les échantillons de cette dernière espèce, testés in vitro dans le bioessai de l’adipogenèse des cellules adipocytes murines 3T3-L1, augmentent l’accumulation intracellulaire des triglycérides, leur conférant ainsi une activité diabétique semblable à la rosiglitazone. Cependant, cette activité était plus faible dans les échantillons à haute teneur en quercétine, cela pouvant ainsi avoir un impact sur la qualité d'un produit de santé naturel fabriqué à partir de cette espèce.Type 2 diabetes has reached epidemic proportions among Canada’s aboriginal populations and affects on average 29% of adult Cree of Eeyou Istchee (CEI). In collaboration with the Cree Board of Health and Social Services of James Bay and the CIHR team in Traditional Antidiabetic Aboriginal Medicines, interviews were held in the CEI communities of Wemindji and Oujé-Bougoumou to identify potential antidiabetic plants. Using a quantitative approach, species mentioned were ranked and compared to the pharmacopoeia of other participating communities. Sixteen and 25 plants were mentioned in Wemindji and Oujé-Bougoumou respectively. Seven new plant and one fungal species were added to the list of potential antidiabetic species, although most of those mentioned were common to the general CEI pharmacopoeia, thus supporting the cultural importance that they hold. Phytochemical analyses of two of these species, Rhododendron groenlandicum and Sarracenia purpurea, were made from accessions harvested throughout Eeyou Istchee. While no pattern was detected in the variation of S. purpurea’s biologically active compounds, phenolic compounds from R. groenlandicum, specifically (+)-catchin, (-)-epicatechin and quercetin-3-galactoside, varied spatially as a function of insolation parameters such as solar radiation or photoperiod. Samples from the latter, tested in vitro in the 3T3-L1 murine adipocytes adipogenesis bioassay, increased the intracellular accumulation of triglycerides, thus conferring it a glitazone-like antidiabetic activity. This activity, however, was weaker in accessions with high quercetin content, which could have an impact on the quality of a natural health product made from this species
Access to Indigenous and allopathic medicines: A systematic review of barriers and facilitators
Background: Globally, Indigenous peoples are the victims of social inequalities in health. Their state of health is much lower than the health of the general population. Colonialism, living conditions and access to care are the main determinants of observed health conditions. The scientific objective of this systematic literature review is to study the facilitators and barriers to access healthcare for both, traditional and allopathic medicines.
Methods: An inclusive search of electronic databases (e.g ProQuest, Ovid, Medline, CINAHL PLUS, Cochrane Library, ApaPsyNet, PsyINFO and Sociological Abstracts databases) of the past 20 years was performed. We retained studies discussing (1) traditional medicine (TM) or allopathic medicine (AM) or both and occurring (2) within Indigenous population worldwide. We made no distinction between research carried out in rural as opposed to urban areas.
Results: A total of 45 studies published between 1996 and 2016 met our inclusion criteria and this speaks to the high interest and contemporary pertinence of accessing both systems of healthcare for Indigenous populations worldwide. Our thematic analysis enabled us to group barriers and facilitators into five categories, namely related to personal, relational, cultural, structural and policy components. As far as barriers and facilitators are concerned, the category that encompasses the most themes is the structural category.
Conclusions: Mutual respect, trust and understanding of each other’s modalities is essential to offer the best healthcare options from both AM and TM to Indigenous peoples and hence pave the way to reducing health inequities. Wellness and strength-based approaches must also be favoured
Access to Indigenous and allopathic medicines: A systematic review of barriers and facilitators
Background: Globally, Indigenous peoples are the victims of social inequalities in health. Their state of health is much lower than the health of the general population. Colonialism, living conditions and access to care are the main determinants of observed health conditions. The scientific objective of this systematic literature review is to study the facilitators and barriers to access healthcare for both, traditional and allopathic medicines.
Methods: An inclusive search of electronic databases (e.g ProQuest, Ovid, Medline, CINAHL PLUS, Cochrane Library, ApaPsyNet, PsyINFO and Sociological Abstracts databases) of the past 20 years was performed. We retained studies discussing (1) traditional medicine (TM) or allopathic medicine (AM) or both and occurring (2) within Indigenous population worldwide. We made no distinction between research carried out in rural as opposed to urban areas.
Results: A total of 45 studies published between 1996 and 2016 met our inclusion criteria and this speaks to the high interest and contemporary pertinence of accessing both systems of healthcare for Indigenous populations worldwide. Our thematic analysis enabled us to group barriers and facilitators into five categories, namely related to personal, relational, cultural, structural and policy components. As far as barriers and facilitators are concerned, the category that encompasses the most themes is the structural category.
Conclusions: Mutual respect, trust and understanding of each other’s modalities is essential to offer the best healthcare options from both AM and TM to Indigenous peoples and hence pave the way to reducing health inequities. Wellness and strength-based approaches must also be favoured
Adipogenic Activity of Wild Populations of Rhododendron groenlandicum, a Medicinal Shrub from the James Bay Cree Traditional Pharmacopeia
The traditional medicinal plant, Labrador tea (Rhododendron groenlandicum (Oeder) Kron & Judd; Ericaceae), present in the pharmacopoeia of the Cree of Eeyou Istchee, has shown glitazone-like activity in the 3T3-L1 adipogenesis bioassay. This activity has been attributed to phenolic compounds, which have been shown to vary in this plant as a function of insolation parameters. The goal of this study was to determine if these changes in phenolic content were pharmacologically significant. Leaves were harvested in 2006 throughout the James Bay region of Northern Quebec and ethanol extracts were tested in vitro using the 3T3-L1 murine cell line adipogenesis bioassay. This traditional medicinal plant was found active in the assay. However, there was no detectable spatial pattern in the accumulation of intracellular triglycerides, suggesting that such patterns previously observed in the phenolic profile of Labrador tea were not pharmacologically significant. Nonetheless, a reduction in the adipogenic activity was observed and associated with higher concentrations of quercetin for which selected environmental variables did not appropriately explain its variation
Nunatsiavut, ‘Our beautiful land’: Inuit landscape ethnoecology in Labrador, Canada
For Inuit in the subarctic transition zone of northeastern Canada, an intimate knowledge of the environment and local biodiversity is crucial for successful traditional activities. This study examines what kinds of landscape features and habitats Inuit of Nunatsiavut recognize and name. During interviews, community members (mostly Elders) were shown photographs from the region, and were asked to describe and name salient types of places in Labrador Inuttitut. The most frequently reported geographical units dealt with the region’s topography (e.g., ‘mountain’, ‘island’, ‘flat-place’), hydrology (e.g., ‘river’, ‘bay’), and superficial characteristics (e.g., ‘bedrock’, ‘permanent snow patch’). Ecological considerations were also prominent, such as plant associations and animal habitats (e.g., ‘shrubby-place’, wetland’, ‘caribou-return-to-place’). Areas were often characterized by a dominant species or substrate type, being named using the plural form of the species/substrate (e.g., napâttuk ‘tree’/ napâttuit ‘forest’, siugak ‘sand’/siugalak ‘sandy-area’). Some types of places reported by Inuit were significant mainly for traditional activities (e.g., ‘berry-patch’, ‘seal-place’, ‘dry-wood-place’, ‘danger-place’), aiding navigation and resource finding. Integrating Inuit conceptions of ecosystems and their component landscape units with those of contemporary science can improve our understanding of subarctic ecology, benefit climate change adaptation strategies and Inuit language/culture conservation initiatives
Listening to Inuit and Naskapi peoples in the eastern Canadian Subarctic: a quantitative comparison of local observations with gridded climate data
International audienc
Ethnobotanical study of medicinal plants by population of Valley of Juruena Region, Legal Amazon, Mato Grosso, Brazil
Ethnopharmacological importance The use of medicinal plants for treatment, cure and prevention of diseases has been described by many people since time immemorial. Because of this use, commercial and scientific interests have emerged, making it necessary to realize ethnobotanical surveys of medicinal plants species, which is important for subsequent chemical and pharmacological bioprospections. Aim of the study This study aimed at surveying, identifying, cataloging and documenting the medicinal plants species used in the Valley of Juruena, Northwestern Mato Grosso, Legal Amazon Brazil for the treatment of various human diseases, as well as assessed the species of interest for bioprospecting potential. Materials and methods Informants were interviewed using semi-structured form to capture information on socio-demographic and ethnopharmacological data of medicinal plants such as vernacular name, uses, geographic origin, habit, form of preparation and part used. Results were analyzed using descriptive and quantitative means: indices of use-report (Ur) and informant consensus factor (ICF), for the selection of plant species with therapeutic potential. Results Three hundred and thirty two (332) plants species belonging to 90 families were reported for medicinal purposes and totaling 3973 use-reports were reported by 365 (92.9%) of the people interviewed. Asteraceae (32.2%), Fabaceae (26.7%) and Lamiaceae (24.4%) families were the most represented, with majority being species native (64.45%) to Brazil. Leaves (64.5%) were the part of the plant most used and infusion (45.7%) was the most utilized form. Gastrointestinal disorders followed by respiratory complaints topped the list of use-reports. The native or naturalized plants with the highest use reports in the order of decreasing absolute frequency per each emic-category are Cymbopogon citratus (DC.) Stapfc (104), Mentha pulegium L. (94), Arrabidaea chica (Humb. & Bonpl.) B. Verl. (97), Alternanthera brasiliana (L.) Kuntze (71), Baccharis crispa Spreng (57), Phyllanthus niruri L. (48), Gossypium barbadense L. (44), Solidago microglossa DC. (40) and Bauhinia forficata L. (20). And the most cited exotics are: Chenopodium ambrosioides L. (151), Aloe vera (L.) Burm. f., (89) and Rosmarinus officinalis L. (72). In some cases, high ICF values were found, which reflects high degree of homogeneity of consensus among informants in this region on medicinal plants. Conclusion The population of Valle of Juruena makes use of a wide array of medicinal plants distributed in all use categories with predominance of those use in the treatments of gastrointestinal and respiratory ailments. The therapeutic potential of some of the species of medicinal importance extensively utilized by the population of the region have been scientifically validated, and are therefore promising prototype of new drugs. However, there are some of these species whose ethnomedicinal uses are yet to be scientifically verified and thus constitute an unexplored terrain for future biological/pharmacological studies