Strategic Study for Sustainable Development of Freshwater Aquaculture in Camagüey

A strategic study of biological-fishing behavior of the main variables determined for extensive freshwater aquaculture was made in facilities of the Camagüey Fishing Company, province of Camagüey, Cuba. The purpose of the study was to evaluate the organizational insertion within the current Cuban social and economic scenario. Several variable sequence graphs were made, and the degree of dependence and ratio among them was determined through the Pearson coefficient. The highest sustainable catch was also calculated, and the state of technical and productive facilities was evaluated as well. Therefore, it was concluded that the current situation of aquaculture does not favor sustainable development, though a number of priority actions were identified: renovation of technical and production facilities, strategic orientation of the fishing efforts in all the water reservoirs, and diversification of fishing produc-tions

A Dynamic Kinetic Asymmetric Heck Reaction for the Simultaneous Generation of Central and Axial Chirality

A highly diastereo- and enantioselective, scalable Pd-catalyzed dynamic kinetic asymmetric Heck reaction of heterobiaryl sulfonates with electron-rich olefins is described. The coupling of 2,3-dihydrofuran or N-boc protected 2,3-dihydropyrrole with a variety of quinoline, quinazoline, phthalazine, and picoline derivatives takes place with simultaneous installation of central and axial chirality, reaching excellent diastereo- and enantiomeric excesses when in situ formed [Pd0/DM-BINAP] was used as the catalyst, with loadings reduced down to 2 mol % in large scale reactions. The coupling of acyclic, electron-rich alkenes can also be performed using a [Pd0/Josiphos ligand] to obtain axially chiral heterobiaryl α-substituted alkenes in high yields and enantioselectivities. Products from Boc-protected 2,3-dihydropyrrole can be easily transformed into N,N ligands or appealing axially chiral, bifunctional proline-type organocatalysts. Computational studies suggest that a β-hydride elimination is the stereocontrolling step, in agreement with the observed stereochemical outcome of the reaction.Ministerio de Ciencia e Innovación (Grants CTQ2016-76908-C2-1-P; CTQ2016-76908-C2-2-P; CTQ2016-78083-P; RYC-2013-12585)European Commission (FEDER Programme)Junta de Andalucía (Grant 2012/FQM 10787)Universidad de Sevilla (Grant No. 1800511201)European Union - Marie Skłodowska-Curie (COFUND—Grant Agreement nº 291780

Estudio estratégico para el desarrollo sostenible de la acuicultura de agua dulce en Camagüey

En el presente trabajo se desarrolló un estudio estratégico del comportamiento biológico-pesquero de las principales variables que intervienen en el proceso de explotación acuícola extensiva en la Empresa Pesquera de Camagüey, Cuba, con fines de evaluar posibilidades y obstáculos para lograr la inserción organizacional en el actual escenario socio-económico cubano; para ello se elaboraron gráficos de secuencia de las variables y se determinó el grado de relación y dependencia de las mismas mediante el coeficiente de correlación de Pearson, además se calculó la captura máxima sostenible y se evaluó el estado de la infraestructura técnico-productiva. Todo ello permitió apreciar que el estado actual de la explotación acuícola no favorece un desarrollo sostenible, pero se identificó un orden de acciones prioritarias en este sentido: renovar la infraestructura técnico-productiva, lograr una orientación estratégica del esfuerzo pesquero en todos los embalses y diversificar las producciones pesqueras.AbstractA strategic study of biological-fishing behavior of the main variables determined for extensive fresh water aquaculture was made in facilities of the Camaguey Fishing Company, province of Camaguey, Cuba. The purpose of the study was to evaluate the organizational insertion within the current Cuban social and economic scenario. Several variable sequence graphs were made, and the degree of dependence and relation among them was determined, through the Pearson coefficient. The highest sustainable capture was also calculated, and the state of technical and productive facilities was evaluated as well. Therefore, it was concluded that the current situation of aquaculture does not favor sustainable development, though a number of priority actions were identified: renovation of technical and production facilities, strategic orientation of the fishing effort in all the water reservoirs, and diversification of fishing productions

Preferencias tróficas de Pterois volitans (Scorpaenidae) en el área costera de Holguín, Cuba

El pez león (Pterois volitans) es una especie arrecifal que ha invadido de una manera vertiginosa el Atlántico Occidental. Este estudio tuvo como objetivo caracterizar la dieta del pez león en la zona costera de Holguín, Cuba. Para ello, se realizaron ocho campañas de muestreo durante el período abril-noviembre de 2016 en seis sitios costeros, incluyendo arrecifes frontales, artificiales y bahías, ubicados entre los 14 y 35 m de profundidad. Se analizó un total de 250 ejemplares con tallas entre 8 y 33 cm de longitud estándar. A través del análisis de sus contenidos estomacales se identificaron 27 tipos de presa, las cuales se agruparon en las categorías tróficas de peces, crustáceos y moluscos. Los peces fueron el componente preferencial en la dieta del pez león en base a los métodos numérico, frecuencia de ocurrencia, gravimétrico e índice de importancia relativa. Dentro de las presas, las especies de peces Holocentrus rufus y Monocanthus tuckeri fueron las más representativas. La dieta del pez león en el área de estudio reflejó la disponibilidad de las presas en cada sitio, lo que sugiere que es un predador oportunista (Índice de Levin = 0.91). No se encontró diferencias estadísticas en relación a la similitud entre los sitios de muestreo a partir del aporte del peso de los diferentes componentes consumidos

Spatiotemporal variations of organochlorine pesticides in an apex predator: Influence of government regulations and farming practices

Background: Intensification of agricultural practices has caused several negative effects to the environment. The use of fertilizers and pesticides may alter geochemical cycles or cause direct wildlife intoxication. Detrimental effects of organochlorine pesticides (OCPs) have forced the authorities to ban or restrict its use. This study evaluates the variation in levels of OCPs in a sentinel species in relation to changes in government regulations and the spatial configuration of agricultural practices around the nests. Methods: Between 2003 and 2007, we analysed OCP levels in 256 blood samples of Eurasian Eagle-owl (Bubo bubo) chicks nesting in area of intensive commercial agriculture with historical frequent use of pesticides, in South-eastern Spain. We studied year-to-year variations in OCP concentrations and their relation with land use configuration around raptor nests by Generalized Linear Mixed Models (GLMM). Results: OCPs were detected in 100% samples surveyed in 2003 and 2004, while dropped to 27% in 2005, 6.8% in 2006 and 6.3% in 2007, coinciding with the ban of OCPs. The presence of the main OCPs was related to agricultural practices. In particular, endosulfan and lindane were related to irrigated crops and urban areas, while DDT-related compounds and dieldrin were associated with dry land farming. Conclusions: OCP concentrations in blood samples of Eurasian Eagle-owls may respond quickly to the implementations of new regulations about the use of agricultural products. This raptor was confirmed as a good sentinel species allowing rapid detection of changes in pesticides use

Entramados emocionales: cuidados, vivencias y redes sociales virtuales

Este volumen explora las emociones a partir de las narrativas y prácticas del cuidado, su relación estrecha y compleja con la vivencia y la experiencia o en sus nexos con las redes virtuales. Los autores, en su estudio, colocan en el centro el análisis del trabajo y regulación emocional de cuidadoras y cuidadores. Dirigido a profesionistas, investigadoras e investigadores, así como estudiantes de las ciencias sociales y humanidades, este libro aborda la virtualidad en las emociones, un ámbito poco explorado por lo que los expertos ensayan propuestas sobre su vinculación con las lógicas mercantiles o sobre el papel del humor virtual en la configuración de la política nacional.ITESO, A.C

Temas Socio-Jurídicos. Volumen 20 No. 42 Junio 2002

Arribamos a la edición número 42 de la revista Temas Socio- Jurídicos tras veinte años de persistente presencia en el medio académico del país, y de haber obtenido nuevamente la homologación como publicación científica por parte del comité de Colciencias. Al cierre de la edición registramos el deceso de tres juristas vinculados a los orígenes de nuestra facultad de derecho, los doctores Carlos Alberto Zuluaga Soto, Hernán Prada Niño y Alvaro Rey Ramírez, así como del humanista Jorge Enrique Valderrama en cuya memoria dedicamos este esfuerzo de la comunidad académica.We arrive at the 42nd edition of the Socio-Legal Issues magazine after twenty years of persistent presence in the media of the country, and having again obtained approval as a scientific publication by the committee of Colciencias. At the close of the edition we recorded the death of three jurists linked to the origins of our law school, doctors Carlos Alberto Zuluaga Soto, Hernán Prada Niño and Álvaro Rey Ramírez, as well as the humanist Jorge Enrique Valderrama in whose memory we dedicate this effort of the academic community

A deletion at Adamts9-magi1 Locus is associated with psoriatic arthritis risk

Objective: Copy number variants (CNVs) have been associated with the risk to develop multiple autoimmune diseases. Our objective was to identify CNVs associated with the risk to develop psoriatic arthritis (PsA) using a genome-wide analysis approach. Methods: A total of 835 patients with PsA and 1498 healthy controls were genotyped for CNVs using the Illumina HumanHap610 BeadChip genotyping platform. Genomic CNVs were characterised using CNstream analysis software and analysed for association using the χ2 test. The most significant genomic CNV associations with PsA risk were independently tested in a validation sample of 1133 patients with PsA and 1831 healthy controls. In order to test for the specificity of the variants with PsA aetiology, we also analysed the association to a cohort of 822 patients with purely cutaneous psoriasis (PsC). Results: A total of 165 common CNVs were identified in the genome-wide analysis. We found a highly significant association of an intergenic deletion between ADAMTS9 and MAGI1 genes on chromosome 3p14.1 (p=0.00014). Using the independent patient and control cohort, we validated the association between ADAMTS9-MAGI1 deletion and PsA risk (p=0.032). Using next-generation sequencing, we characterised the 26 kb associated deletion. Finally, analysing the PsC cohort we found a lower frequency of the deletion compared with the PsA cohort (p=0.0088) and a similar frequency to that of healthy controls (p>0.3). Conclusions: The present genome-wide scan for CNVs associated with PsA risk has identified a new deletion associated with disease risk and which is also differential from PsC risk

Effectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy:Study protocol of a cluster randomized clinical trial (Multi-PAP project)

This study was funded by the Fondo de Investigaciones Sanitarias ISCIII (Grant Numbers PI15/00276, PI15/00572, PI15/00996), REDISSEC (Project Numbers RD12/0001/0012, RD16/0001/0005), and the European Regional Development Fund ("A way to build Europe").Background: Multimorbidity is associated with negative effects both on people's health and on healthcare systems. A key problem linked to multimorbidity is polypharmacy, which in turn is associated with increased risk of partly preventable adverse effects, including mortality. The Ariadne principles describe a model of care based on a thorough assessment of diseases, treatments (and potential interactions), clinical status, context and preferences of patients with multimorbidity, with the aim of prioritizing and sharing realistic treatment goals that guide an individualized management. The aim of this study is to evaluate the effectiveness of a complex intervention that implements the Ariadne principles in a population of young-old patients with multimorbidity and polypharmacy. The intervention seeks to improve the appropriateness of prescribing in primary care (PC), as measured by the medication appropriateness index (MAI) score at 6 and 12months, as compared with usual care. Methods/Design: Design:pragmatic cluster randomized clinical trial. Unit of randomization: family physician (FP). Unit of analysis: patient. Scope: PC health centres in three autonomous communities: Aragon, Madrid, and Andalusia (Spain). Population: patients aged 65-74years with multimorbidity (≥3 chronic diseases) and polypharmacy (≥5 drugs prescribed in ≥3months). Sample size: n=400 (200 per study arm). Intervention: complex intervention based on the implementation of the Ariadne principles with two components: (1) FP training and (2) FP-patient interview. Outcomes: MAI score, health services use, quality of life (Euroqol 5D-5L), pharmacotherapy and adherence to treatment (Morisky-Green, Haynes-Sackett), and clinical and socio-demographic variables. Statistical analysis: primary outcome is the difference in MAI score between T0 and T1 and corresponding 95% confidence interval. Adjustment for confounding factors will be performed by multilevel analysis. All analyses will be carried out in accordance with the intention-to-treat principle. Discussion: It is essential to provide evidence concerning interventions on PC patients with polypharmacy and multimorbidity, conducted in the context of routine clinical practice, and involving young-old patients with significant potential for preventing negative health outcomes. Trial registration: Clinicaltrials.gov, NCT02866799Publisher PDFPeer reviewe