AN ONTOLOGY-BASED KNOWLEDGE REPRESENTATION USING ANALYTIC HIERARCHY PROCESS FOR ENHANCING SELECTION OF PRODUCT PREFERENCES

Product alternatives, which emerges from large number of websites during searching, accounts for some hesitation experienced by customers in selecting satisfying product. As a result, making useful decision with many trade-off considerations becomes a major cause of such problem. Several approaches have been employed for product selection such as, fuzzy logic, Neuro-fuzzy, and weighted least square. However, these could not solve the problem of inconsistency and irrelevant judgement that occur in decision making. In this study, Ontology-based Analytic Hierarchy Process (AHP) was used for enhancing selection of product preferences. The model involved three fundamental components: product gathering, selection and decision making. Ontology Web Language (OWL) was utilized to define ontology in expressing product information gathering in a standard and structured manner for the purpose of interoperability while AHP was employed in making optimal choices. The procedure accepts customers’ perspectives as inputs which are classified into criteria and sub-criteria. Owl was created to foster customers’ interaction and priority estimation tool for AHP in order to generate the consistency ratio of individual judgements. The model was benchmarked with Geometric Mean (GM), Eigenvector (EV), Normalized Column Sum (NCS) Weighted Least Square (WLS) and Fuzzy Preference Programming (FPP). First and second order total deviations and violation rate were the performance parameters evaluation with AHP. The results showed that the minimum and maximum units of products are 2,452and 3,574, respectively. These implied that the proposed model was consistent, relevant and reflected a non-violation of judgment in selection of product preferences. &nbsp

Solid Waste Management in a Leprosarium in Southwestern Nigeria

Waste from healthcare institutions generally ought to be treated and disposed hygienically. However, the type of institution normally determines the material component and the nature of the waste generated whether it is hazardous or non-hazardous, infectious or non-infectious waste. Also health status of an individual or community is a function of standard of living, medical services available, social amenities and hygienic environment normally determined through impact assessment. These have been examined in relation to the leprosarium in Ogbomosho, Southwestern Nigeria. The leprosarium under study consists of a clinic and three camps located at about 1000m from the clinic. The leprosarium housed 30 patients, while the camps served as home for about 140 people under rehabilitation together including their children. As one of the health institutions, it is apparent that the waste generated is heterogeneous mixture of both general municipal waste and bio-medical waste. The percentage of biomedical waste which is hazardous in nature is low about 1.0% with average generation rate of 0.13kg/day while that of non-hazardous, non-infectious general waste is 0.288kg/person/day. The average waste generation rate in term of mass is determined to be between 0.084 – 0.095kg/person/day which reveals the poor status and rural nature of these leper settlements. The waste components consist of bandages and swabs, paper, nylon and plastic, domestic waste, animal waste (mostly goat manure), wood ash and yard trimmings which are being disposed on open dump sites and sometimes by open burning which are unhygienic causing health hazards. Accumulation of these waste components without proper disposal initiates its putrefaction which produces offensive odour. In addition, absence of adequate sanitary facilities has promoted open defecation which is a source of infectious, diseases. As an economical, appropriate and useful method of waste disposal, composting was proposed since it is found relevant and acceptable  for the leprosarium and the settlements around as the waste generated is predominantly biodegradable and decomposable materials. Key words: Solid waste, bio-medical waste, characterization, waste disposal, compostin

Community perception of school-based mass drug administration program for soil-transmitted helminths and Schistosomiasis in Ogun State, Nigeria

BACKGROUND: Neglected tropical diseases, such as soil-transmitted helminths and Schistosomiasis, are prevalent in sub-Saharan Africa, particularly Ogun State, Nigeria. School-based mass drug administration program is the primary control intervention, but the coverage and uptake of this intervention have been inadequate. This study aimed to investigate community perceptions of school-based mass drug administration programs for these infections in Ogun State, Nigeria, and identify the barriers to their uptake and coverage. METHODOLOGY/PRINCIPAL FINDINGS: The study used a qualitative research approach involving focus group discussions and in-depth interviews with community members and stakeholders engaged in neglected tropical disease control programs in Ogun State, Nigeria. A semi-structured questionnaire guided the exploration of ideas, and the data were analyzed using the QRS Nvivo 12 software package. The study found several barriers, such as the influence of parents, lack of sufficient knowledge, and side effects. The study recommended strategies such as improving community sensitization and engagement, drug distribution and performance, and enhancing partner collaboration and coordination to improve the school-based mass drug administration programs. CONCLUSIONS/SIGNIFICANCE: The study revealed correct perceptions of transmission but some misconceptions about disease causation, transmission, and drug safety. Participants expressed a desire for better sensitization campaigns and more assurances of their safety. The study recommends strengthening health education messages and increasing the visibility of on-site medical personnel. The findings have implications for improving the performance of these programs and reducing the burden of intestinal parasitic infections in the community. The study highlights the need for community engagement and education, health system support, and partner collaboration to successfully implement mass drug administration programs

Physical losses could partially explain modest carotenoid retention in dried food products from biofortified cassava

Gari, a fermented and dried semolina made from cassava, is one of the most common foods in West Africa. Recently introduced biofortified yellow cassava containing provitamin A carotenoids could help tackle vitamin A deficiency prevalent in those areas. However there are concerns because of the low retention of carotenoids during gari processing compared to other processes (e.g. boiling). The aim of the study was to assess the levels of true retention in trans–β-carotene during gari processing and investigate the causes of low retention. Influence of processing step, processor (3 commercial processors) and variety (TMS 01/ 1371; 01/1368 and 01/1412) were assessed. It was shown that low true retention (46% on average) during gari processing may be explained by not only chemical losses (i.e. due to roasting temperature) but also by physical losses (i.e. due to leaching of carotenoids in discarded liquids): true retention in the liquid lost from grating negatively correlated with true retention retained in the mash (R = -0.914). Moreover, true retention followed the same pattern as lost water at the different processing steps (i.e. for the commercial processors). Variety had a significant influence on true retention, carotenoid content, and trans-cis isomerisation but the processor type had little effect. It is the first time that the importance of physical carotenoid losses was demonstrated during processing of biofortified crops

Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.

BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700

Microsatellite Variability of Two Populations of Clarias gariepinus (Siluriformes, Clariidae) in Nigeria

The study evaluated the genetic signatures of the fishes from the two populations and compared the pattern of differentiation of the two populations with a view to separating the species from the different populations into possible sub-species. Forty (40) specimens were collected from River Niger (Lokoja) and Asejire Resevoir. The DNA of the twenty (20) specimens from each population extracted from the muscle tissue using phenol-chloroform extraction (PCE) method was subjected to microsatellite DNA analysis. Seven (7) microsatellite markers (Cga01, Cga02, Cga03, Cga05, Cga06, Cga09 and Cga10) were used in the analysis. Microsatellite DNA analysis of the two populations revealed significant differentiation between the two populations as shown by the high values of heterozygosity, low level of inbreeding and non-conformance to Hardy-Weinberg’s equilibrium. It is concluded from the study that microsatellite analysis showed a high potentiality for separation of the populations

Wastewater management in a Nigerian leper colony

Wastewater from infected leprosy patients is expected to contain considerably higher concentrations of pathogens than standard domestic wastewater and, therefore, is more infectious. Isolation of lepers' is thought to prevent the spread of a wide range of infectious diseases that could potentially be contacted through direct or indirect exposure from an infected person's wastewater in the surrounding environment. However, inappropriate management of wastewater and sewage from these camps has led to contamination of the surrounding environment, typical in Nigeria. This study aims to recommend safe, efficient and sustainable management of wastewater and sewage in a lepers' colony in Ogbomosho, south west Nigeria. The case study is privately owned, with three camps and a leprosarium. Information and data (primary and secondary) were collected from medical personnel (doctors, matrons and nurses), management staff and lepers in each camp, through hand- delivered and orally explained questionnaires and physical observations. Wastewater samples could not be collected for analysis because there were no septic tanks or drainage for sewage and wastewater disposal. Two of the camps have no sanitary disposal system, with the remaining camp occupying one pit latrine, which is inadequate in prevention of environmental pollution. The leprosarium itself uses the pit latrine as an improvised bathroom and for defecation. Therefore, a further aim of this work is to provide a sewage treatment facility to cope with the problem of unsanitary disposal of excreta. The majority of wastewater is generated from bathing, personal washing, ward clean-ups, patients' services and general house-keeping activities. The approximate quantity of water being used per head per day was found to be 64-79 litres, resulting in ~60 litres of wastewater that was discharged without treatment. To ameliorate environmental risks that leper colonies are responsible for, the pour-flush toilet was recommended based on its suitability for the physical condition of lepers, its ease of operation, maintenance and sustainability, minimum water usage for flushing and low construction costs. However, this must be fed into a well designed and sited septic tank and soak-away pit to receive foul sewage and sullage, respectively. Ideally, construction of a proper in-built bathroom is recommended for both the leprosarium and camps. © 2011 Vilnius Gediminas Technical University (VGTU) Press Technika

Genetic analysis of grain yield and resistance of extra‐early‐maturing maize inbreds to northern corn leaf blight

Maize (Zea mays L.) is a food security crop in sub-Saharan Africa (SSA). Incidence of northern corn leaf blight (NCLB), caused by Exserohilum turcicum, in lowlands of SSA during the past decade has caused 30–70% reduction in maize yield. This study (a) examined the combining abilities of extra-early maize (EEM) inbreds and classified them into heterotic groups; (b) elucidated gene action controlling resistance to NCLB; (c) assessed grain yield (GYLD) and yield stability of EEM hybrids underNCLB infection; and (d) identified testers. One hundred and fiftyEEMhybrids, obtained by crossing 15 inbreds each of white- and yellow-endosperm maize using the North Carolina Design II, plus six checks, were evaluated in nine environments, six of which were inoculated with an isolate of E. turcicum and three of which were non-inoculated in 2018 and 2019. The white and yellow inbreds were placed in three heterotic groups using the heterotic grouping based on general combining ability (GCA) of multiple traits and stability of GYLD using the genotype plus genotype × environment (GGE) biplot analysis. The GCA, specific combining ability (SCA) and genotype × environment (G×E) interactions were significant for GYLD, disease severity, and other measured traits. The GCA effects were more important than the SCA effects for GYLD and NCLB severity scores across environments, implying that recurrent selection could facilitate improvement for GYLD and NCLB resistance. Three inbred testers and four single-cross testers were identified for developing high-yielding NCLB-resistant hybrids. Four white and five yellow single-cross hybrids were identified for on-farm testing and possible commercialization