Thirumantiram and Prasada Yoga

Mystic syllable is the god of all universes. It includes both living and non-living things. Among them, the universal law is that what is born dies and what dies is born. Siddhas are those who have a different lifestyle and they followed some kind of Thavam in their life. They believed Thavam is the only solution to attain God. All these are the constituents of the Agamas given by God. Overall, there are 28 agamas. Thavam is the only way to merge with God. Shiva is the one who first preached to Parvati. Subsequently, Nandi received nine Agamas among them. Among them Thirumular provides Thirumantram. Among them Atanga Yoga, Kesari Yoga, Parianga Yoga, Kundalini Yoga, Prasada Yoga are the ways to reach God. Among these Prasada Yoga gives a blissful life. With reference with the texts given by Thirumoolar and Siddhars this article briefly explains Prasada Yoga its duration of meditation, sound, spiritual experience, benefits, etc

Results on Möbius index for standard graphs

This paper is concerned with calculating the Möbius index values and arrived results for a few standard graphs. Some standard graphs which we considered are Path graph, Cycle graph, Complete Graph, Star Graph, Shell graph, Wheel Graph, Gear graph, Helm Graph, the Web graph, Flower Graph.Publisher's Versio

Assessing growth performance and agro-meteorological indices of green gram (Vigna radiata L.) varieties influenced by soil amendments and foliar application under sodic soil in Cauvery delta zone of Tamil Nadu

Green gram prefers neutral soil reactions and is sensitive to saline and alkaline soil conditions. Around 2.1 % of the country's geographical area is salt-affected, of which 3.77 million ha is sodic soil. Rehabilitation of salt-affected soil using drainage is expensive and leaching with good quality water is not feasible. To overcome this, a field experiment was conducted at Anbil Dharmalingam Agricultural College and Research Institute, Tiruchirappalli, during summer 2022 to study the effect of soil amendments and foliar nutrition under sodic soil. The experiment was laid out in a split-plot design with three replications. The treatments comprised of different varieties in main plots (M1, M2, M3, M4, M5 and M6)  and different soil amendments with foliar application in sub plots (S1, S2 and S3). The results showed that VBN (Gg) 4 + gypsum @ 50 % GR + pressmud @ 10 t ha-1 + FS of brassinosteroid 0.2 ppm (M4S1) registered higher plant height (18.31, 31.52 & 60.63 cm), DMP (907, 1932 & 2969 kg ha-1), CGR (3.02, 6.83 & 4.15 g m-2 d-1) and SPAD value (37.56, 41.62 & 30.57) at 30, 45 DAS and harvest. The same treatments increased grain and haulm yield of 997 and 2232 kg ha-1. It also increased all agro-meteorological indices viz., GDD, HTU, PTU, RTD and HUE of green gram. However, comparable results were obtained with VBN (Gg) 4 + gypsum @ 50 % GR + CSR GROMOR @ 25 kg ha-1 + FS of brassinosteroid 0.2 ppm (M4S2)

Comparative Evaluation of Various Statistical Models and Its Accuracy for Landslide Risk Mapping: A Case Study on Part of Himalayan Region, India

Among other natural hazards, Landslides are the most prominent and frequently occurring natural disaster in the state of Himachal Pradesh with higher socio-economical losses. About 0.42 million sq.kms of area are prone to landslide activities in our country that is excluding the snow covered areas. The current research focuses on estimating the landslide risk zones of the Shimla Tehsil, Himachal Pradesh using various statistical models. Landslide contributing factors as such Landuse Landcover, Elevation, Slope, Lithology, Soil, Geology and Geomorphology has been used to assess the Landslide risk factors. Data obtained from LANDSAT 8 OLI sensors, SRTM DEM, Soil and Land Use Survey of India and SOI Toposheets have been used as sources. Weighted Overlay, Fuzzy logic and Analytical Hierarchical Process models will be used to categorize the Vulnerability and risk Zones of the study area. The causative factors were analyzed and processed in GIS environment. These values will be then being integrated using various studied models to produce individual landslide vulnerability and risk zones. The results reveal that most of the study area falls under Very Low risk category with a total coverage of 67.34%. Low and Moderate area covers about 23% and 9.13% of the study area. Higher risk areas only account for about 0.46%. Higher percent of the study area is mostly covered by settlements. National highways, Metal roads, Slopes and Denser settlements are located along the Moderate and low risk areas. The results retrieved from the WOM model reveals a total of 55% of the area comes under very low category. Low and Moderate category covers about 31.4% and 10.6% of the study area. High and Very High category cover a total of 1.9% together

Experimental investigation on no fines concrete by addition of natural fibres

No fines concrete is a type of lightweight concrete that is made without the use of fine aggregates. In this experimental investigation, the effect of adding bamboo and sugarcane fibres on the mechanical properties of no fines concrete was studied. The specimens were prepared by replacing a portion of the coarse aggregates with 1.5% of bamboo and sugarcane fibres by volume. The specimens were tested for compressive strength and splitting tensile strength at 7, 14, and 28 days of curing. The results showed that the addition of bamboo and sugarcane fibres improved the mechanical properties of no fines concrete. The optimal percentage of fibre content was found to be 1.5% by volume, which improved the compressive strength and splitting tensile strength by 23% and 18% respectively, compared to the control specimens. Additionally, the use o natural fibres in no-fine concrete can result in a more sustainable and eco-friendly construction material

Performance assessment on manufacturing of unfired bricks using industrial wastes

This paper presents eco-friendly unburnt bricks made up of fly ash, waste plastic powder, waste glass powder, lime, gypsum and crusher sand as alternatives to conventional burnt clay bricks for sustainable development. The research focuses on the maximum utilization of industrial waste in eco-friendly unburnt brick production. Materials are characterized according to their chemical and geotechnical properties. In this research, we use a milled waste glass powder of size less than 600μm and plastic powder obtained from plastic waste of size less than 600μm are added along with crushed sand, gypsum, lime and fly ash with various mix proportions concerning FaL-G mix concept. All the proportions were taken on a weight basis. Compressive strength, water absorption, and efflorescence are the key parameters chosen for comparing the innovative brick with conventional fly ash brick. There are five different mixes (Type A, B, C, D & E) are made in this research. The plastic and glass powders are replaced by crusher sand at the increased rate of 2% in every mix whereas 2%,4%,6%,8%, and 10%. It was found that the type B bricks have 17.63% strength was increased when compared to base mix. From the test results, type B bricks have enhanced mechanical performance when compared to all other mixes

Malnutrition, nutritional interventions and clinical outcomes of patients with acute small bowel obstruction : results from a national, multicentre, prospective audit

Objective: The aim of this study was to assess the nutritional status of patients presenting with small bowel obstruction (SBO), along with associated nutritional interventions and clinical outcomes. Design: Prospective cohort study. Setting: 131 UK hospitals with acute surgical services. Participants: 2069 adult patients with a diagnosis of SBO were included in this study. The mean age was 67.0 years and 54.7% were female. Primary and secondary outcome measures: Primary outcome was in-hospital mortality. Secondary outcomes recorded included: major complications (composite of in-hospital mortality, reoperation, unplanned intensive care admission and 30-day readmission), complications arising from surgery (anastomotic leak, wound dehiscence), infection (pneumonia, surgical site infection, intra-abdominal infection, urinary tract infection, venous catheter infection), cardiac complications, venous thromboembolism and delirium. Results: Postoperative adhesions were the most common cause of SBO (49.1%). Early surgery (<24 hours postadmission) took place in 30.0% of patients, 22.0% underwent delayed operation and 47.9% were managed non-operatively. Malnutrition as stratified by Nutritional Risk Index was common, with 35.7% at moderate risk and 5.7% at severe risk of malnutrition. Dietitian review occurred in just 36.4% and 55.9% of the moderate and severe risk groups. In the low risk group, 30.3% received nutritional intervention compared with 40.7% in moderate risk group and 62.7% in severe risk group. In comparison to the low risk group, patients who were at severe or moderate risk of malnutrition had 4.2 and 2.4 times higher unadjusted risk of in-hospital mortality, respectively. Propensity-matched analysis found no difference in outcomes based on use or timing of parenteral nutrition. Conclusions: Malnutrition on admission is associated with worse outcomes in patients with SBO, and marked variation in management of malnutrition was observed. Future trials should focus on identifying effective and cost-effective nutritional interventions in SBO

Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell Recruitment to the Human Colon but Is Not Responsible for Differences Observed in Dendritic Cell Subsets, Phenotype, and Function Between the Proximal and Distal Colon.

BACKGROUND & AIMS: Most knowledge about gastrointestinal (GI)-tract dendritic cells (DC) relies on murine studies where CD103+ DC specialize in generating immune tolerance with the functionality of CD11b+/- subsets being unclear. Information about human GI-DC is scarce, especially regarding regional specifications. Here, we characterized human DC properties throughout the human colon. METHODS: Paired proximal (right/ascending) and distal (left/descending) human colonic biopsies from 95 healthy subjects were taken; DC were assessed by flow cytometry and microbiota composition assessed by 16S rRNA gene sequencing. RESULTS: Colonic DC identified were myeloid (mDC, CD11c+CD123-) and further divided based on CD103 and SIRPα (human analog of murine CD11b) expression. CD103-SIRPα+ DC were the major population and with CD103+SIRPα+ DC were CD1c+ILT3+CCR2+ (although CCR2 was not expressed on all CD103+SIRPα+ DC). CD103+SIRPα- DC constituted a minor subset that were CD141+ILT3-CCR2-. Proximal colon samples had higher total DC counts and fewer CD103+SIRPα+ cells. Proximal colon DC were more mature than distal DC with higher stimulatory capacity for CD4+CD45RA+ T-cells. However, DC and DC-invoked T-cell expression of mucosal homing markers (β7, CCR9) was lower for proximal DC. CCR2 was expressed on circulating CD1c+, but not CD141+ mDC, and mediated DC recruitment by colonic culture supernatants in transwell assays. Proximal colon DC produced higher levels of cytokines. Mucosal microbiota profiling showed a lower microbiota load in the proximal colon, but with no differences in microbiota composition between compartments. CONCLUSIONS: Proximal colonic DC subsets differ from those in distal colon and are more mature. Targeted immunotherapy using DC in T-cell mediated GI tract inflammation may therefore need to reflect this immune compartmentalization

Outcomes following small bowel obstruction due to malignancy in the national audit of small bowel obstruction

Introduction Patients with cancer who develop small bowel obstruction are at high risk of malnutrition and morbidity following compromise of gastrointestinal tract continuity. This study aimed to characterise current management and outcomes following malignant small bowel obstruction. Methods A prospective, multicentre cohort study of patients with small bowel obstruction who presented to UK hospitals between 16th January and 13th March 2017. Patients who presented with small bowel obstruction due to primary tumours of the intestine (excluding left-sided colonic tumours) or disseminated intra-abdominal malignancy were included. Outcomes included 30-day mortality and in-hospital complications. Cox-proportional hazards models were used to generate adjusted effects estimates, which are presented as hazard ratios (HR) alongside the corresponding 95% confidence interval (95% CI). The threshold for statistical significance was set at the level of P ≤ 0.05 a-priori. Results 205 patients with malignant small bowel obstruction presented to emergency surgery services during the study period. Of these patients, 50 had obstruction due to right sided colon cancer, 143 due to disseminated intraabdominal malignancy, 10 had primary tumours of the small bowel and 2 patients had gastrointestinal stromal tumours. In total 100 out of 205 patients underwent a surgical intervention for obstruction. 30-day in-hospital mortality rate was 11.3% for those with primary tumours and 19.6% for those with disseminated malignancy. Severe risk of malnutrition was an independent predictor for poor mortality in this cohort (adjusted HR 16.18, 95% CI 1.86 to 140.84, p = 0.012). Patients with right-sided colon cancer had high rates of morbidity. Conclusions Mortality rates were high in patients with disseminated malignancy and in those with right sided colon cancer. Further research should identify optimal management strategy to reduce morbidity for these patient groups

National prospective cohort study of the burden of acute small bowel obstruction

Background Small bowel obstruction is a common surgical emergency, and is associated with high levels of morbidity and mortality across the world. The literature provides little information on the conservatively managed group. The aim of this study was to describe the burden of small bowel obstruction in the UK. Methods This prospective cohort study was conducted in 131 acute hospitals in the UK between January and April 2017, delivered by trainee research collaboratives. Adult patients with a diagnosis of mechanical small bowel obstruction were included. The primary outcome was in‐hospital mortality. Secondary outcomes included complications, unplanned intensive care admission and readmission within 30 days of discharge. Practice measures, including use of radiological investigations, water soluble contrast, operative and nutritional interventions, were collected. Results Of 2341 patients identified, 693 (29·6 per cent) underwent immediate surgery (within 24 h of admission), 500 (21·4 per cent) had delayed surgery after initial conservative management, and 1148 (49·0 per cent) were managed non‐operatively. The mortality rate was 6·6 per cent (6·4 per cent for non‐operative management, 6·8 per cent for immediate surgery, 6·8 per cent for delayed surgery; P = 0·911). The major complication rate was 14·4 per cent overall, affecting 19·0 per cent in the immediate surgery, 23·6 per cent in the delayed surgery and 7·7 per cent in the non‐operative management groups (P < 0·001). Cox regression found hernia or malignant aetiology and malnutrition to be associated with higher rates of death. Malignant aetiology, operative intervention, acute kidney injury and malnutrition were associated with increased risk of major complication. Conclusion Small bowel obstruction represents a significant healthcare burden. Patient‐level factors such as timing of surgery, acute kidney injury and nutritional status are factors that might be modified to improve outcomes