Modeling photonic links in Verilog-A

Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (pages 59-60).Integrated photonic links are a promising emerging technology that can relieve the interconnect bottleneck in core-to-core and core-to-memory communications of modern processors. Developing and optimizing photonic link systems requires simulation of integrated photonic devices side-by-side with electronic devices at the device, circuit, and system level. In previous efforts to simulate photonic links, the optical and the electrical signals were treated in separate simulators, which resulted in some loss of accuracy. In this thesis, a library of photonic device models is developed in Verilog-A for use in seamless simulation of opto-electronic circuits in Cadence.by Ekaterina Kononov.M. Eng

Photon-mediated long range coupling of two Andreev level qubits

In a superconducting weak link, the supercurrent is carried by Andreev bound states (ABSs) formed by the phase-coherent reflection of electrons and their time-reversed partners. A single, highly transmissive ABS can serve as an ideal, compact two-level system, due to a potentially large energy difference to the next ABS. While the coherent manipulation of such Andreev levels qubits (ALQs) has been demonstrated, a long-range coupling between two ALQs, necessary for advanced qubit architectures, has not been achieved, yet. Here, we demonstrate a coherent remote coupling between two ALQs, mediated by a microwave photon in a novel superconducting microwave cavity coupler. The latter hosts two modes with different coupling rates to an external port. This allows us to perform fast readout of each qubit using the strongly coupled mode, while the weakly coupled mode is utilized to mediate the coupling between the qubits. When both qubits are tuned into resonance with the latter mode, we find excitation spectra with avoided-crossings, in very good agreement with the Tavis-Cummings model. Based on this model, we identify highly entangled two-qubit states for which the entanglement is mediated over a distance of six millimeters. This work establishes ALQs as compact and scalable solid-state qubits.Comment: 13 pages, 7 figure

The seasonal cycle of the greenhouse gas balance of a continental tundra site in the Indigirka lowlands, NE Siberia

International audienceCarbon dioxide and methane fluxes were measured at a tundra site near Chokurdakh, in the lowlands of the Indigirka river in north-east Siberia. This site is one of the few stations on Russian tundra and it is different from most other tundra flux stations in its continentality. A suite of methods was applied to determine the fluxes of NEE, GPP, Reco and methane, including eddy covariance, chambers and leaf cuvettes. Net carbon dioxide fluxes were unusually high, compared with other tundra sites, with NEE=?92 g C m?2 yr?1, which is composed of an Reco=+141 g C m?2 yr?1 and GPP=?232 g C m?2 yr?1. This large carbon dioxide sink may be explained by the continental climate, that is reflected in low winter soil temperatures (?14°C), reducing the respiration rates, and short, relatively warm summers, stimulating high photosynthesis rates. Interannual variability in GPP was dominated by the frequency of light limitation (Rg ?2), whereas Reco depends most directly on soil temperature and time in the growing season, which serves as a proxy of the combined effects of active layer depth, leaf area index, soil moisture and substrate availability. The methane flux, in units of global warming potential, was +28 g C-CO2e m?2 yr?1, so that the greenhouse gas balance was ?64 g C-CO2e m?2 yr?1. Methane fluxes depended only slightly on soil temperature and were highly sensitive to hydrological conditions and vegetation composition

Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis

Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy with a complex microenvironment. Dichotomous tumour-promoting and -restrictive roles have been ascribed to the tumour microenvironment, however the effects of individual stromal subsets remain incompletely characterised. Here, we describe how heterocellular Oncostatin M (OSM) - Oncostatin M Receptor (OSMR) signalling reprograms fibroblasts, regulates tumour growth and metastasis. Macrophage-secreted OSM stimulates inflammatory gene expression in cancer-associated fibroblasts (CAFs), which in turn induce a pro-tumourigenic environment and engage tumour cell survival and migratory signalling pathways. Tumour cells implanted in Osm-deficient (Osm(−/−)) mice display an epithelial-dominated morphology, reduced tumour growth and do not metastasise. Moreover, the tumour microenvironment of Osm(−/−) animals exhibit increased abundance of α smooth muscle actin positive myofibroblasts and a shift in myeloid and T cell phenotypes, consistent with a more immunogenic environment. Taken together, these data demonstrate how OSM-OSMR signalling coordinates heterocellular interactions to drive a pro-tumourigenic environment in PDA

Standalone vertex finding in the ATLAS muon spectrometer

A dedicated reconstruction algorithm to find decay vertices in the ATLAS muon spectrometer is presented. The algorithm searches the region just upstream of or inside the muon spectrometer volume for multi-particle vertices that originate from the decay of particles with long decay paths. The performance of the algorithm is evaluated using both a sample of simulated Higgs boson events, in which the Higgs boson decays to long-lived neutral particles that in turn decay to bbar b final states, and pp collision data at √s = 7 TeV collected with the ATLAS detector at the LHC during 2011