6 research outputs found
Exploring Relationship Description: A Report from the Describing Relationships Workshop, Simmons College, February 2018
Archivists have included relationship information as a component of contextual and content description; however, they have not been called on to formalize that information. Rather, relationships have been identified and defined through informal narrative contexts, and depend on the archivist’s interpretative work and determination. Additionally, descriptive standards provide little guidance on the explicit description of relationships. To begin to address these issues, a group of archivists gathered in Boston to explore the challenges and opportunities in describing relationships. This paper serves as an account of that workshop from two perspectives: first, it documents the results of the day\u27s discussions and provides some preliminary recommendations, and second, it provides an account and evaluation of the strategy of a local, face-to-face event to explore the inherently complex and interpretive activity of the description of relationships
Remembering Ada Long, May 20, 1945–February 4, 2024
As part of the National Collegiate Honors Council’s collection of essays honoring the life and work of Dr. Ada Long (1945–2024), the authors reflect on the personal and professional impact she has made in the honors experience. See https://youtube.com/live/EwdleBW1Rf8?feature=share to view the entire Celebration of Life that was held June 8, 2024
A New Chicken Genome Assembly Provides Insight into Avian Genome Structure
The importance of the Gallus gallus (chicken) as a model organism and agricultural animal merits a continuation of sequence assembly improvement efforts. We present a new version of the chicken genome assembly (Gallus_gallus-5.0; GCA_000002315.3), built from combined long single molecule sequencing technology, finished BACs, and improved physical maps. In overall assembled bases, we see a gain of 183 Mb, including 16.4 Mb in placed chromosomes with a corresponding gain in the percentage of intact repeat elements characterized. Of the 1.21 Gb genome, we include three previously missing autosomes, GGA30, 31, and 33, and improve sequence contig length 10-fold over the previous Gallus_gallus-4.0. Despite the significant base representation improvements made, 138 Mb of sequence is not yet located to chromosomes. When annotated for gene content, Gallus_gallus-5.0 shows an increase of 4679 annotated genes (2768 noncoding and 1911 protein-coding) over those in Gallus_gallus-4.0. We also revisited the question of what genes are missing in the avian lineage, as assessed by the highest quality avian genome assembly to date, and found that a large fraction of the original set of missing genes are still absent in sequenced bird species. Finally, our new data support a detailed map of MHC-B, encompassing two segments: one with a highly stable gene copy number and another in which the gene copy number is highly variable. The chicken model has been a critical resource for many other fields of study, and this new reference assembly will substantially further these efforts
Controlled Shape Memory Behavior of a Smectic Main-Chain Liquid Crystalline Elastomer
A smectic
main-chain liquid crystalline elastomer (LCE), with controlled
shape memory behavior, is synthesized by polymerizing a biphenyl-based
epoxy monomer with an aliphatic carboxylic acid curing agent. Microstructures
of the LCEs, including their liquid crystallinity and cross-linking
density, are modified by adjusting the stoichiometric ratio of the
reactants to tailor the thermomechanical properties and shape memory
behavior of the material. Thermal and liquid crystalline properties
of the LCEs, characterized using differential scanning calorimetry
and dynamic mechanical analysis, and structural analysis, performed
using small-angle and wide-angle X-ray scattering, show that liquid
crystallinity, cross-linking density, and network rigidity are strongly
affected by the stoichiometry of the curing reaction. With appropriate
structural modifications it is possible to tune the thermal, dynamic
mechanical, and thermomechanical properties as well as the shape memory
and thermal degradation behavior of LCEs
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A New Chicken Genome Assembly Provides Insight into Avian Genome Structure
The importance of the Gallus gallus (chicken) as a model organism and agricultural animal merits a continuation of sequence assembly improvement efforts. We present a new version of the chicken genome assembly (Gallus_gallus-5.0; GCA_000002315.3), built from combined long single molecule sequencing technology, finished BACs, and improved physical maps. In overall assembled bases, we see a gain of 183 Mb, including 16.4 Mb in placed chromosomes with a corresponding gain in the percentage of intact repeat elements characterized. Of the 1.21 Gb genome, we include three previously missing autosomes, GGA30, 31, and 33, and improve sequence contig length 10-fold over the previous Gallus_gallus-4.0. Despite the significant base representation improvements made, 138 Mb of sequence is not yet located to chromosomes. When annotated for gene content, Gallus_gallus-5.0 shows an increase of 4679 annotated genes (2768 noncoding and 1911 protein-coding) over those in Gallus_gallus-4.0. We also revisited the question of what genes are missing in the avian lineage, as assessed by the highest quality avian genome assembly to date, and found that a large fraction of the original set of missing genes are still absent in sequenced bird species. Finally, our new data support a detailed map of MHC-B, encompassing two segments: one with a highly stable gene copy number and another in which the gene copy number is highly variable. The chicken model has been a critical resource for many other fields of study, and this new reference assembly will substantially further these efforts