31 research outputs found
ICT in schools survey 2004
This document is the presentation and analysis of the findings of the ICT in schools survey in 2004 with attention given to computer-pupil ratios, staff use of ICT, e-confidence, e-safety and utilisation of specific technologies such as digital projectors
Microwave-assisted hydrothermal synthesis of carbon monolith via a soft-template method using resorcinol and formaldehyde as carbon precursor and pluronic F127 as template
A new microwave-assisted hydrothermal synthesis of carbon monolith is reported in this work. The process uses microwave heating at 100 °C under acidic condition by employing a triblock copolymer F127 as the template, and resorcinol–formaldehyde as the carbon precursor. Scanning electron microscopy, Fourier transform infrared spectroscopy, nitrogen sorption measurements, transmission electron microscopy, X-ray studies and thermogravimetic analysis were used to characterize the synthesized material. The carbon monolith is crack-free, mesoporous and has a high surface area of 697 m²/g. The results demonstrate that the microwave-assisted hydrothermal synthesis is a fast and simple approach to obtain carbon monoliths, as it reduces effectively the synthesis time from hours to a few minutes which could be an advantage in the large scale production of the material
Perception des avantages offerts par les TIC dans les bibliothèques publiques en France : le point de vue des usagers (La)
TNS, une société indépendante spécialisée dans les études, présente à l’international, a été mandatée par la Bill & Melinda Gates foundation (fondation Bill & Melinda Gates) pour mener une étude auprès de 17 pays de l’Union européenne. Cette étude est destinée à évaluer la perception des bibliothèques publiques et l’usage qui en est fait. Son objectif est de comprendre l’influence des bibliothèques publiques sur la vie de leurs usagers, au niveau de l’Union européenne
Enquête paneuropéenne destinée à évaluer les perceptions des utilisateurs à l’égard des avantages liés aux technologies de l’information et de la communication dans les bibliothèques publiques
TNS, une société indépendante spécialisée dans les études, présente à l’international, a été mandatée par la Bill & Melinda Gates foundation (fondation Bill & Melinda Gates) pour mener une étude auprès de 17 pays de l’Union européenne afin d\u27évaluer les perceptions des utilisateurs à l’égard des avantages liés aux technologies de l’information et de la communication dans les bibliothèques publique. La Bpi en a été le relais en France
Light Curve Templates and Galactic Distribution of RR Lyrae Stars from Sloan Digital Sky Survey Stripe 82
We present an improved analysis of halo substructure traced by RR Lyrae stars
in the SDSS stripe 82 region. With the addition of SDSS-II data, a revised
selection method based on new ugriz light curve templates results in a sample
of 483 RR Lyrae stars that is essentially free of contamination. The main
result from our first study persists: the spatial distribution of halo stars at
galactocentric distances 5--100 kpc is highly inhomogeneous. At least 20% of
halo stars within 30 kpc from the Galactic center can be statistically
associated with substructure. We present strong direct evidence, based on both
RR Lyrae stars and main sequence stars, that the halo stellar number density
profile significantly steepens beyond a Galactocentric distance of ~30 kpc, and
a larger fraction of the stars are associated with substructure. By using a
novel method that simultaneously combines data for RR Lyrae and main sequence
stars, and using photometric metallicity estimates for main sequence stars
derived from deep co-added u-band data, we measure the metallicity of the
Sagittarius dSph tidal stream (trailing arm) towards R.A.2h-3h and Dec~0 deg to
be 0.3 dex higher ([Fe/H]=-1.2) than that of surrounding halo field stars.
Together with a similar result for another major halo substructure, the
Monoceros stream, these results support theoretical predictions that an early
forming, smooth inner halo, is metal poor compared to high surface brightness
material that have been accreted onto a later-forming outer halo. The mean
metallicity of stars in the outer halo that are not associated with detectable
clumps may still be more metal-poor than the bulk of inner-halo stars, as has
been argued from other data sets.Comment: Submitted to ApJ, 68 pages, 26 figures, supplemental material (light
curves, templates, animation) can be downloaded from
http://www.astro.washington.edu/bsesar/S82_RRLyr.htm
Collecting and exploiting data to understand a nation's sexual health needs: Implications for the British National Surveys of Sexual Attitudes and Lifestyles (Natsal).
No abstract available
Adherent Human Alveolar Macrophages Exhibit a Transient Pro-Inflammatory Profile That Confounds Responses to Innate Immune Stimulation
Alveolar macrophages (AM) are thought to have a key role in the immunopathogenesis of respiratory diseases. We sought to test the hypothesis that human AM exhibit an anti-inflammatory bias by making genome-wide comparisons with monocyte derived macrophages (MDM). Adherent AM obtained by bronchoalveolar lavage of patients under investigation for haemoptysis, but found to have no respiratory pathology, were compared to MDM from healthy volunteers by whole genome transcriptional profiling before and after innate immune stimulation. We found that freshly isolated AM exhibited a marked pro-inflammatory transcriptional signature. High levels of basal pro-inflammatory gene expression gave the impression of attenuated responses to lipopolysaccharide (LPS) and the RNA analogue, poly IC, but in rested cells pro-inflammatory gene expression declined and transcriptional responsiveness to these stimuli was restored. In comparison to MDM, both freshly isolated and rested AM showed upregulation of MHC class II molecules. In most experimental paradigms ex vivo adherent AM are used immediately after isolation. Therefore, the confounding effects of their pro-inflammatory profile at baseline need careful consideration. Moreover, despite the prevailing view that AM have an anti-inflammatory bias, our data clearly show that they can adopt a striking pro-inflammatory phenotype, and may have greater capacity for presentation of exogenous antigens than MDM
Recommended from our members
Nursing considerations to complement the Surviving Sepsis Campaign guidelines
Objectives: To provide a series of recommendations based on the best available evidence to guide clinicians providing nursing care to patients with severe sepsis.
Design: Modified Delphi method involving international experts and key individuals in subgroup work and electronic-based discussion among the entire group to achieve consensus.
Methods: We used the Surviving Sepsis Campaign guidelines as a framework to inform the structure and content of these guidelines. We used the Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) system to rate the quality of evidence from high (A) to very low (D) and to determine the strength of recommendations, with grade 1 indicating clear benefit in the septic population and grade 2 indicating less confidence in the benefits in the septic population. In areas without complete agreement between all authors, a process of electronic discussion of all evidence was undertaken until consensus was reached. This process was conducted independently of any funding.
Results: Sixty-three recommendations relating to the nursing care of severe sepsis patients are made. Prevention recommendations relate to education, accountability, surveillance of nosocomial infections, hand hygiene, and prevention of respiratory, central line-related, surgical site, and urinary tract infections, whereas infection management recommendations related to both control of the infection source and transmission-based precautions. Recommendations related to initial resuscitation include improved recognition of the deteriorating patient, diagnosis of severe sepsis, seeking further assistance, and initiating early resuscitation measures. Important elements of hemodynamic support relate to improving both tissue oxygenation and macrocirculation. Recommendations related to supportive nursing care incorporate aspects of nutrition, mouth and eye care, and pressure ulcer prevention and management. Pediatric recommendations relate to the use of antibiotics, steroids, vasopressors and inotropes, fluid resuscitation, sedation and analgesia, and the role of therapeutic end points.
Conclusion: Consensus was reached regarding many aspects of nursing care of the severe sepsis patient. Despite this, there is an urgent need for further evidence to better inform this area of critical care