316 research outputs found

    Comets at radio wavelengths

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    Comets are considered as the most primitive objects in the Solar System. Their composition provides information on the composition of the primitive solar nebula, 4.6 Gyr ago. The radio domain is a privileged tool to study the composition of cometary ices. Observations of the OH radical at 18 cm wavelength allow us to measure the water production rate. A wealth of molecules (and some of their isotopologues) coming from the sublimation of ices in the nucleus have been identified by observations in the millimetre and submillimetre domains. We present an historical review on radio observations of comets, focusing on the results from our group, and including recent observations with the Nan\c{c}ay radio telescope, the IRAM antennas, the Odin satellite, the Herschel space observatory, ALMA, and the MIRO instrument aboard the Rosetta space probe.Comment: Proceedings of URSI France scientific days, "Probing Matter with Electromagnetic Waves", 24-25 March 2015, Paris. To be published in C. R. Physiqu

    Observations of the 18-cm OH lines of comet 103P/Hartley 2 at Nan\c{c}ay in support to the EPOXI and Herschel missions

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    The 18-cm radio lines of the OH radical were observed in comet 103P/Hartley 2 with the Nan\c{c}ay radio telescope in support to its flyby by the EPOXI mission and to observations with the Herschel Space Observatory. The OH lines were detected from 24 September to 15 December 2010. These observations are used to estimate the gas expansion velocity within the coma to 0.83 \pm 0.08 km/s in October 2010. The water production increased steeply but progressively before perihelion, and reached 1.9 \pm 0.3 X 10E28 s-1 just before the EPOXI flyby.Comment: Accepted for publication in Icarus (6 pages, 4 figures

    RFI mitigation strategies for phased-array SKA concepts

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    Proceedings available on http://www.skads-eu.org/PDF/limelette2_v1.1.pdf ISBN : 978-90-805434-5-4International audienceAlthough the Square Kilometer Array (SKA) will be located in remote areas, astronomical observations may be hampered by man-made radio frequency interference (RFI). In this paper we consider possible interference mitigation options in relation to complexity and cost. As RFI signals will be present even in remote places (e.g. satellite signals and signals from airplanes), SKA design has to consider and take into account effects of interference. These effects may concern linearity of the analogue and digital signal processing chain, such as the number of (analogue-digital converter, ADC) bits, low-noise amplifier (LNA) dynamic range, and (fibre) signal transport dynamic range. RFI signals may also influence the astronomical end-product as additive noise with certain spectral, temporal and spatial properties. As these properties usually differ from the astronomical signal properties, interference can in principle be mitigated. Mitigation however, always includes a cost both in terms of money and often also in terms of signal integrity. RFI mitigation counter measures therefore should be balanced in the sense that the cost of including RFI measures in the design is justified in terms of regained spectrum

    The chemical diversity of comets

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    A fundamental question in cometary science is whether the different dynamical classes of comets have different chemical compositions, which would reflect different initial conditions. From the ground or Earth orbit, radio and infrared spectroscopic observations of a now significant sample of comets indeed reveal deep differences in the relative abundances of cometary ices. However, no obvious correlation with dynamical classes is found. Further results come, or are expected, from space exploration. Such investigations, by nature limited to a small number of objects, are unfortunately focussed on short-period comets (mainly Jupiter-family). But these in situ studies provide "ground truth" for remote sensing. We discuss the chemical differences in comets from our database of spectroscopic radio observations, which has been recently enriched by several Jupiter-family and Halley-type comets.Comment: In press in Earth, Moon and Planets (proceedings of the workshop "Future Ground-based Solar System Research: Synergies with Space Probes and Space Telescopes", Portoferraio, Isola d'Elba, Livorno (Italy), 8-12 September 2008). 6 pages with 2 figure

    Gas and dust productions of Comet 103P/Hartley 2 from millimetre observations: Interpreting rotation-induced time variations

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    Comet 103P/Hartley 2 made a close approach to the Earth in October 2010. It was the target of an extensive observing campaign including ground- and orbit-based observatories and was visited by the Deep Impact spacecraft in the framework of its mission extension EPOXI. We present observations of HCN and CH_3OH emission lines conducted with the IRAM Plateau de Bure interferometer on 22–23, 28 October and 4, 5 November 2010 at 1.1, 1.9 and 3.4 mm wavelengths. The thermal emission from the dust coma and nucleus is detected simultaneously. Interferometric images with unprecedented spatial resolution of ∌100 to ∌500 km are obtained. A sine–wave like variation of the thermal continuum is observed in the 23 October data, that we associate with the nucleus thermal light curve. The nucleus contributes up to 30–55% of the observed continuum emission. The dust thermal emission is used to measure the dust production rate. The inferred large dust-to-gas ratio (in the range 2–6) can be explained by the unusual activity of the comet for its size, which allows decimeter size particles and large boulders to be entrained by the gas due to the small nucleus gravity. The rotational temperature of CH_3OH is measured with beam radii from ∌150 km to ∌1500 km. We attribute the increase from ∌35 K to ∌46 K with increasing beam size to radiative processes. The HCN production rate displays strong rotation-induced temporal variations, varying from ∌0.3 × 10^(25) s^(−1) to ∌2.0 × 10^(25) s^(−1) in the 4–5 November period. The HCN production curve, as well as the CO_2 and H_2O production curves measured by EPOXI, are interpreted with a geometric model which takes into account the complex rotational state of 103P/Hartley 2 and its shape. The HCN and H_2O production curves are in phase, showing that these molecules have common sources. The ∌1.7 h delay, in average, of the HCN and H_2O production curves with respect to the CO_2 production curve suggests that HCN and H_2O are mainly produced by subliming icy grains. The scale length of production of HCN is determined to be on the order of 500–1000 km, implying a mean velocity of 100–200 m s^(−1) for the icy grains producing HCN. From the time evolution of the insolation of the nucleus, we show that the CO_2 production is modulated by the insolation of the small lobe of the nucleus. The three-cycle pattern of the production curves reported earlier is best explained by an overactivity of the small lobe in the longitude range 0–180°. The good correlation between the insolation of the small lobe and CO_2 production is consistent with CO_2 being produced from small depths below the surface. The time evolution of the velocity offset of the HCN lines, as well as the displacement of the HCN photocenter in the interferometric maps, are overall consistent with this interpretation. Other localized sources of gas on the nucleus surface are also suggested

    Ethyl alcohol and sugar in comet C/2014 Q2 (Lovejoy)

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    The presence of numerous complex organic molecules (COMs; defined as those containing six or more atoms) around protostars shows that star formation is accompanied by an increase of molecular complexity. These COMs may be part of the material from which planetesimals and, ultimately, planets formed. Comets represent some of the oldest and most primitive material in the solar system, including ices, and are thus our best window into the volatile composition of the solar protoplanetary disk. Molecules identified to be present in cometary ices include water, simple hydrocarbons, oxygen, sulfur, and nitrogen-bearing species, as well as a few COMs, such as ethylene glycol and glycine. We report the detection of 21 molecules in comet C/2014 Q2 (Lovejoy), including the first identification of ethyl alcohol (ethanol, C_2H_5OH) and the simplest monosaccharide sugar glycolaldehyde (CH_2OHCHO) in a comet. The abundances of ethanol and glycolaldehyde, respectively 5 and 0.8% relative to methanol (0.12 and 0.02% relative to water), are somewhat higher than the values measured in solar-type protostars. Overall, the high abundance of COMs in cometary ices supports the formation through grain-surface reactions in the solar system protoplanetary disk

    Changes in resting-state functionally connected parieto-frontal networks after videogame practice

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    Neuroimaging studies provide evidence for organized intrinsic activity under task-free conditions. This activity serves functionally relevant brain systems supporting cognition. Here, we analyze changes in resting-state functional connectivity after videogame practice applying a test–retest design. Twenty young females were selected from a group of 100 participants tested on four standardized cognitive ability tests. The practice and control groups were carefully matched on their ability scores. The practice group played during two sessions per week across 4 weeks (16 h total) under strict supervision in the laboratory, showing systematic performance improvements in the game. A group independent component analysis (GICA) applying multisession temporal concatenation on test–retest resting-state fMRI, jointly with a dual-regression approach, was computed. Supporting the main hypothesis, the key finding reveals an increased correlated activity during rest in certain predefined resting state networks (albeit using uncorrected statistics) attributable to practice with the cognitively demanding tasks of the videogame. Observed changes were mainly concentrated on parietofrontal networks involved in heterogeneous cognitive functions

    Type-3 Secretion System-induced pyroptosis protects Pseudomonas against cell-autonomous immunity

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    Inflammasome-induced pyroptosis comprises a key cell-autonomous immune process against intracellular bacteria, namely the generation of dying cell structures. These so-called pore-induced intracellular traps (PITs) entrap and weaken intracellular microbes. However, the immune importance of pyroptosis against extracellular pathogens remains unclear. Here, we report that Type-3 secretion system (T3SS)-expressing Pseudomonas aeruginosa ( P. aeruginosa ) escaped PIT immunity by inducing a NLRC4 inflammasome-dependent macrophage pyroptosis response in the extracellular environment. To the contrary, phagocytosis of Salmonella Typhimurium promoted NLRC4-dependent PIT formation and the subsequent bacterial caging. Remarkably, T3SS-deficient Pseudomonas were efficiently sequestered within PIT-dependent caging, which favored exposure to neutrophils. Conversely, both NLRC4 and caspase-11 deficient mice presented increased susceptibility to T3SS-deficient P. aeruginosa challenge, but not to T3SS-expressing P. aeruginosa. Overall, our results uncovered that P. aeruginosa uses its T3SS to overcome inflammasome-triggered pyroptosis, which is primarily effective against intracellular invaders. Importance Although innate immune components confer host protection against infections, the opportunistic bacterial pathogen Pseudomonas aeruginosa ( P. aeruginosa ) exploits the inflammatory reaction to thrive. Specifically the NLRC4 inflammasome, a crucial immune complex, triggers an Interleukin (IL)-1ÎČ and -18 deleterious host response to P. aeruginosa . Here, we provide evidence that, in addition to IL-1 cytokines, P. aeruginosa also exploits the NLRC4 inflammasome-induced pro-inflammatory cell death, namely pyroptosis, to avoid efficient uptake and killing by macrophages. Therefore, our study reveals that pyroptosis-driven immune effectiveness mainly depends on P. aeruginosa localization. This paves the way toward our comprehension of the mechanistic requirements for pyroptosis effectiveness upon microbial infections and may initiate targeted approaches in order to ameliorate the innate immune functions to infections. Graphical abstract Macrophages infected with T3SS-expressing P. aeruginosa die in a NLRC4-dependent manner, which allows bacterial escape from PIT-mediated cell-autonomous immunity and neutrophil efferocytosis. However, T3SS-deficient P. aeruginosa is detected by both NLRC4 and caspase-11 inflammasomes, which promotes bacterial trapping and subsequent efferocytosis of P. aeruginosa -containing-PITs by neutrophils

    The International College of Neuro-Psychopharmacology (CINP) treatment guidelines for Bipolar disorder in adults (CINP-BD-2017), part 2:Review, grading of the evidence and a precise algorithm

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