Mass balance of the Greenland Ice Sheet from 1992 to 2018

In recent decades, the Greenland Ice Sheet has been a major contributor to global sea-level rise1,2, and it is expected to be so in the future3. Although increases in glacier flow4–6 and surface melting7–9 have been driven by oceanic10–12 and atmospheric13,14 warming, the degree and trajectory of today’s imbalance remain uncertain. Here we compare and combine 26 individual satellite measurements of changes in the ice sheet’s volume, flow and gravitational potential to produce a reconciled estimate of its mass balance. Although the ice sheet was close to a state of balance in the 1990s, annual losses have risen since then, peaking at 335 ± 62 billion tonnes per year in 2011. In all, Greenland lost 3,800 ± 339 billion tonnes of ice between 1992 and 2018, causing the mean sea level to rise by 10.6 ± 0.9 millimetres. Using three regional climate models, we show that reduced surface mass balance has driven 1,971 ± 555 billion tonnes (52%) of the ice loss owing to increased meltwater runoff. The remaining 1,827 ± 538 billion tonnes (48%) of ice loss was due to increased glacier discharge, which rose from 41 ± 37 billion tonnes per year in the 1990s to 87 ± 25 billion tonnes per year since then. Between 2013 and 2017, the total rate of ice loss slowed to 217 ± 32 billion tonnes per year, on average, as atmospheric circulation favoured cooler conditions15 and as ocean temperatures fell at the terminus of Jakobshavn Isbræ16. Cumulative ice losses from Greenland as a whole have been close to the IPCC’s predicted rates for their high-end climate warming scenario17, which forecast an additional 50 to 120 millimetres of global sea-level rise by 2100 when compared to their central estimate

CD4 T Cell Antigens from Staphylococcus aureus Newman Strain Identified following Immunization with Heat-Killed Bacteria

Staphylococcus aureus is a commensal bacterium associated with the skin and mucosal surfaces of humans and animals that can also cause chronic infection. The emergence of antibiotic-resistant strains such as methicillin-resistant S. aureus (MRSA) and strains causing chronic intramammary infections (IMI) in cows results in severe human and livestock infections. Conventional approaches to vaccine development have yielded only a few noneffective vaccines against MRSA or IMI strains, so there is a need for improved vaccine development. CD4 T lymphocytes are required for promoting gamma interferon (IFN-γ) mediated immunoglobulin isotype switching in B lymphocytes to produce high-affinity IgG antibodies and IFN-γ-mediated phagocyte activation for an effective resolution of bacterial infection. However, the lack of known CD4 T cell antigens from S. aureus has made it difficult to design effective vaccines. The goal of this study was to identify S. aureus proteins recognized by immune CD4 T cells. Using a reverse genetics approach, 43 antigens were selected from the S. aureus Newman strain. These included lipoproteins, proteases, transcription regulators, an alkaline shock protein, conserved-domain proteins, hemolysins, fibrinogen-binding protein, staphylokinase, exotoxin, enterotoxin, sortase, and protein A. Screening of expressed proteins for recall T cell responses in outbred, immune calves identified 13 proteins that share over 80% sequence identity among MRSA or IMI strains. These may be useful for inclusion in a broadly protective multiantigen vaccine against MRSA or IMI

Mass balance of the Greenland Ice Sheet from 1992 to 2018

The Greenland Ice Sheet has been a major contributor to global sea-level rise in recent decades1,2, and it is expected to continue to be so3. Although increases in glacier flow4,5,6 and surface melting7,8,9 have been driven by oceanic10,11,12 and atmospheric13,14 warming, the magnitude and trajectory of the ice sheet’s mass imbalance remain uncertain. Here we compare and combine 26 individual satellite measurements of changes in the ice sheet’s volume, flow and gravitational potential to produce a reconciled estimate of its mass balance. The ice sheet was close to a state of balance in the 1990s, but annual losses have risen since then, peaking at 345 ± 66 billion tonnes per year in 2011. In all, Greenland lost 3,902 ± 342 billion tonnes of ice between 1992 and 2018, causing the mean sea level to rise by 10.8 ± 0.9 millimetres. Using three regional climate models, we show that the reduced surface mass balance has driven 1,964 ± 565 billion tonnes (50.3 per cent) of the ice loss owing to increased meltwater runoff. The remaining 1,938 ± 541 billion tonnes (49.7 per cent) of ice loss was due to increased glacier dynamical imbalance, which rose from 46 ± 37 billion tonnes per year in the 1990s to 87 ± 25 billion tonnes per year since then. The total rate of ice loss slowed to 222 ± 30 billion tonnes per year between 2013 and 2017, on average, as atmospheric circulation favoured cooler conditions15 and ocean temperatures fell at the terminus of Jakobshavn Isbræ16. Cumulative ice losses from Greenland as a whole have been close to the rates predicted by the Intergovernmental Panel on Climate Change for their high-end climate warming scenario17, which forecast an additional 70 to 130 millimetres of global sea-level rise by 2100 compared with their central estimate

Mass balance of the Greenland Ice Sheet from 1992 to 2018

In recent decades, the Greenland Ice Sheet has been a major contributor to global sea-level rise1,2, and it is expected to be so in the future3. Although increases in glacier flow4–6 and surface melting7–9 have been driven by oceanic10–12 and atmospheric13,14 warming, the degree and trajectory of today’s imbalance remain uncertain. Here we compare and combine 26 individual satellite measurements of changes in the ice sheet’s volume, flow and gravitational potential to produce a reconciled estimate of its mass balance. Although the ice sheet was close to a state of balance in the 1990s, annual losses have risen since then, peaking at 335 ± 62 billion tonnes per year in 2011. In all, Greenland lost 3,800 ± 339 billion tonnes of ice between 1992 and 2018, causing the mean sea level to rise by 10.6 ± 0.9 millimetres. Using three regional climate models, we show that reduced surface mass balance has driven 1,971 ± 555 billion tonnes (52 of the ice loss owing to increased meltwater runoff. The remaining 1,827 ± 538 billion tonnes (48 of ice loss was due to increased glacier discharge, which rose from 41 ± 37 billion tonnes per year in the 1990s to 87 ± 25 billion tonnes per year since then. Between 2013 and 2017, the total rate of ice loss slowed to 217 ± 32 billion tonnes per year, on average, as atmospheric circulation favoured cooler conditions15 and as ocean temperatures fell at the terminus of Jakobshavn Isbræ16. Cumulative ice losses from Greenland as a whole have been close to the IPCC’s predicted rates for their high-end climate warming scenario17, which forecast an additional 50 to 120 millimetres of global sea-level rise by 2100 when compared to their central estimate

Mass balance of the Greenland Ice Sheet from 1992-2018

This dataset consists of the time series of mass change of the Greenland Ice Sheet and its contribution to global sea level between 1980 and 2018 derived from satellite measurements. The dataset presented here is a reconciled estimate of mass balance estimates from three independent satellite-based techniques - gravimetry, altimetry and input-output method - and its associated uncertainty. This dataset is part of the Ice Sheet Mass Balance Inter-comparison Exercise (IMBIE). The total mass change as well as the partition between surface and dynamics mass balance are provided in this dataset. This work is an outcome of the Ice Sheet Mass Balance Inter-Comparison Exercise (IMBIE) supported by the ESA Climate Change Initiative and the NASA Cryosphere Program. Andrew Shepherd was additionally supported by a Royal Society Wolfson Research Merit Award and the UK Natural Environment Research Council Centre for Polar Observation and Modelling (cpom30001)

Antarctic and Greenland Ice Sheet mass balance 1992-2020 for IPCC AR6

This dataset contains rates of mass change and cumulative mass change and their associated uncertainty for the Antarctic Ice Sheet (in its entirety and split into West Antarctica, East Antarctica and the Antarctic Peninsula), the Greenland Ice Sheet, and their sum between 1992 and 2020. The data are reconciled estimates of mass balance from three independent satellite-based techniques: altimetry, gravimetry and input-output method. This dataset is part of the Ice Sheet Mass Balance Intercomparison Exercise (IMBIE). This work is an outcome of the Ice Sheet Mass Balance Inter-Comparison Exercise IMBIE) supported by the ESA Climate Change Initiative and the NASA Cryosphere Program. Andrew Shepherd was additionally supported by a Royal Society Wolfson Research Merit Award and the UK Natural Environment Research Council Centre for Polar Observation and Modelling (cpom30001)