People as agents of the neoliberal project: A longitudinal study of school to work transitions in Spain

Abstract:The main purpose of this paper is to describe and analyse some of the processes through which people acquire labour dispositions working for the neoliberal project promotion in a natural and legitimate way. The authors believe that the transitions from school to work provide an ideal opportunity to study such processes. The research took place in the Spanish village of Colindres from 2013 to 2015. We developed the investigation through an anthropological methodolo gy and used different tools as longitudinal interviews and ethnographic fieldwork. In this way, we selected high school students who share significant features related to their family origins and formative period. The authors conclude by discussing how the salaried classes impose upon themselves those labour mechanics and techniques applied by advocates of neoliberal policies: job insecurity, salary precariousness, labour mobility, time flexibility, and job rotation. In this case, we have found that family, peer group and close community in Colindres establish a framework in which young people naturally learn how to face up to their precarious labour experiences without conflict. Finally, the labour marketplace obtains what it needs: an adult who makes his own free decisions as a precarious worker and a low-level consumer

Attitudes towards the effects of COVID-19 on the environment.

Ante los cambios biopsicosociales de la adolescencia algunas personas presentan alteraciones psicológicas asociadas al peso, alimentación e imagen corporal. Por tal motivo, el presente estudio tuvo como objetivo, identificar la insatisfacción corporal y el nivel de riesgo de trastornos alimentarios, así como, analizar la relación de la imagen corporal con las actitudes y conductas alimentarias de riesgo en adolescentes de ambos sexos, habitantes del Estado de México. Participaron 131 adolescentes de ambos sexos, que contestaron tres instrumentos: Cuestionario de imagen corporal, Cuestionario de actitudes alimentarias y Cuestionario de conductas alimentarias de riesgo. Los resultados indican no existen diferencias significativas en las variables evaluadas entre mujeres y hombres. Se encontró un 8.4% de insatisfacción corporal y 6.1% actitudes alimentarias de riesgo, no existieron casos de riesgo alto en las conductas alimentarias de riesgo, ni conductas compensatoria; la insatisfacción corporal se relaciona con la preocupación por peso y figura y la dieta restrictiva. Se concluye, que la sobrevaloración de la imagen corporal se asocia con actitudes y conductas que pueden perjudicar el desarrollo saludable del adolescente. Se requieren intervenciones de promoción desarrollo saludable del adolescente y prevención de trastornos alimentarios en ambientes educativos y comunitarios factorial que explicaba el 35% de la varianza total, aunque el diseño de la investigación limitó los resultados al entorno del estudio, lo que sugiere la extensión del trabajo hacia el contraste del modelo propuesto

Attitudes towards the effects of COVID-19 on the enviroment

Resumen: La pandemia del SARS CoV-2 y la enfermedad Covid-19 han matado alrededor de dos millones y propiciado subregistros identi cados como portadores asintoma?ticos, pero sus efectos tambie?n han sido pronunciados en las actitudes de las personas ante esta problema?tica, la gestio?n de los gobiernos y efectos en el medio ambiente, principalmente en aquellos entornos donde los i?ndices de contagio y letalidad han sido desproporcionados a los escenarios fatalistas, generando expectativas de contagio y contaminacio?n inusitadas. Es el caso de Me?xico en donde se esperaban 65 mil muertes y hasta enero de 2021 se contabilizan 150 mil vi?ctimas. El objetivo del presente trabajo fue especi car un modelo para el estudio de actitudes hacia los efectos de la pandemia en el medio ambiente. Se realizo? un trabajo exploratorio, transversal y correlacional con 100 estudiantes, considerando su con namiento y uso intensivo de tecnologi?as, dispositivos y redes electro?nicas. Se encontro? una estructura factorial que explicaba el 35% de la varianza total, aunque el disen?o de la investigacio?n limito? los resultados al entorno del estudio, lo que sugiere la extensio?n del trabajo hacia el contraste del modelo propuesto.Abstract: The SARS CoV-2 pandemic and the Covid-19 disease have killed around two million and led to under-registrations identified as asymptomatic carriers, but their effects have also been pronounced on people?s attitudes to this problem, government management, and Effects on the environment, mainly in those environments where contagion and lethality rates have been disproportionate to fatalistic scenarios, generating unusual expectations of contagion and contamination. This is the case of Mexico, where 65 thousand deaths were expected and until January 2021 there are 150 thousand victims. The objective of the present work was to specify a model for the study of attitudes towards the effects of the pandemic on the environment. An exploratory, cross-sectional and correlational work was carried out with 100 students, considering their confinement and intensive use of electronic technologies, devices and networks. A factorial structure was found that explained 35% of the total variance, although the research design limited the results to the study environment, suggesting the extension of the work towards the contrast of the proposed model

Governance of electoral preferences: Contrast of a model of consensus expectations and intention to vote in students of a public university

Resumen: El sistema político en el que es posible observar las similitudes y diferencias entre grupos a favor y en contra de candidatos presidenciales con base en procesos de negociación, mediación, conciliación y arbitraje en torno a la gestión y administración de Tecnologías de Información y Comunicación es conocido como gobernanza. Se trata de un fenómeno creciente en la medida en que se aproximan las elecciones locales o federales y se exacerban las redes digitales como instrumentos de promoción o disuasión de un candidato. En ese sentido, el objetivo del presente estudio fue explorar la relación entre las preferencias y expectativas con respecto a las intenciones de voto en una muestra no probabilística de estudiantes usuarios de redes digitales. A partir de un modelo estructural [?2 = 214,35 (47gl) p = 0,007; GFI = 0,990; CFI = 0,997; RMSSEA = 0,001] se encontró que el factor de expectativas de consenso determinó a las intenciones de voto (0,56). Se discuten los alcances y límites del análisis factorial exploratorio de ejes principales con una rotación promax simple y oblicua con respecto a la confirmación de una estructura ortogonal.Abstract: The political system in which it is possible to observe the similarities and differences between groups for and against presidential candidates based on processes of negotiation, mediation, conciliation and arbitration around the management and administration of Information and Communication Technologies is known as governance. Thisis a growing phenomenon as local or federal elections approach and digital networks are exacerbated as instruments for the promotion or dissuasion of a candidate. In this sense, the objective of the present study was to explore the relationship between preferences and expectations regarding voting intentions in a non-probabilistic sample student?s users of digital networks. From a structural model [?2 = 214.35 (47gl) p = 0.007; GFI = 0.990; CFI = 0.997; RMSSEA = 0.001] it was found that the consensus expectation factor determined the intentions to vote (0.56). The scope and limits of the exploratory factor analysis of main axes with a simple and oblique promax rotation with respect to the confirmation of an orthogonal structure are discussed

The agenda of the institutionalist administration: Specification of a digital model of entrepreneurship

Resumen: Antecedentes. Los estudios del institucionalismo educativo advierten; 1) la administración de una cultura y liderazgo tradicional como eje rector de los programas académicos; 2) el establecimiento de una agenda centrada en la gestión del conocimiento, el emprendimiento y la innovación; 3) las alianzas estratégicas entre universidades y empresas como eje central de la formación profesional; 4) las redes colaborativas multidisciplinares. Objetivo. Especificar un modelo para la investigación del emprendimiento digital. Método. Se llevó a cabo un estudio no experimental, transversal y exploratorio con una selección no probabilística de fuentes indexadas en repositorios de la UNAM y UAEMEX. Resultados. La especificación del modelo incluye cinco hipótesis explicativas de las trayectorias de relaciones de dependencia entre ocho variables ?creencias, valores, percepciones, conocimientos, motivos, actitudes, intenciones y comportamiento. Discusión. En virtud de que el modelo especificado pretende anticipar el emprendimiento como resultado de la administración institucionalista y la gestión del conocimiento, emprendimiento e innovación, se recomienda su contraste empírico.Conclusión. La especificación del modelo establece las diferencias entre docentes, estudiantes y administrativos con respecto a la evaluación, acreditación y certificación de la calidad de los procesos y los productos académicos, así como anticipa escenarios de gestión del conocimiento, el emprendimiento y la innovación.Abstract: Background. Studies warn educational institutionalism; 1) administration of a traditional culture and leadership as a guiding principle of academic programs; 2) the establishment of an agenda focused on knowledge management, entrepreneurship and innovation; 3) strategic partnerships between universities and enterprises as the core of vocational training; 4) multidisciplinary collaborative networks. Objective. Specify a model for research of digital entrepreneurship. Method. A non-experimental, cross-sectional and exploratory study with a nonrandom selection of sources indexed repositories UNAM and UAEMEX took place. Results. Model specification includes five explanatory hypothesis paths dependency relationships between variables eight-beliefs, values, perceptions, knowledge, motives, attitudes, intentions and behavior. Discussion. Under the specified model aims to anticipate the enterprise as a result of the institutionalist management and knowledge management, entrepreneurship and innovation, its empirical test is recommended. Conclusion. Model specification establishes the differences between teachers, students and administrators regarding the evaluation, accreditation and certification of the quality of academic processes and products as well as scenarios anticipated knowledge management, entrepreneurship and innovation

Especificación de un modelo para el estudio de la percepción de utilidad

A model is a data management, production and transfer system organized in explanatory trends of past, current and future relationships. The emphasis on each suggests decision making and strategy execution. The objective of this work was to specify a model for of the perception of utility. An exploratory and cross-sectional study was conducted with a selection of 186 students from a public university in central Mexico, considering their participation in the system of professional practices and social service in local organizations. The validity of the instrument that found a one-dimensional variable that explained 43% of the variance was established, but the research design limited the results to the research scenario, suggesting the extension of the work

A novel Alzheimer disease locus located near the gene encoding tau protein

This is the author accepted manuscript. The final version is available from the publisher via the DOI in this recordAPOE ε4, the most significant genetic risk factor for Alzheimer disease (AD), may mask effects of other loci. We re-analyzed genome-wide association study (GWAS) data from the International Genomics of Alzheimer's Project (IGAP) Consortium in APOE ε4+ (10 352 cases and 9207 controls) and APOE ε4- (7184 cases and 26 968 controls) subgroups as well as in the total sample testing for interaction between a single-nucleotide polymorphism (SNP) and APOE ε4 status. Suggestive associations (P<1 × 10-4) in stage 1 were evaluated in an independent sample (stage 2) containing 4203 subjects (APOE ε4+: 1250 cases and 536 controls; APOE ε4-: 718 cases and 1699 controls). Among APOE ε4- subjects, novel genome-wide significant (GWS) association was observed with 17 SNPs (all between KANSL1 and LRRC37A on chromosome 17 near MAPT) in a meta-analysis of the stage 1 and stage 2 data sets (best SNP, rs2732703, P=5·8 × 10-9). Conditional analysis revealed that rs2732703 accounted for association signals in the entire 100-kilobase region that includes MAPT. Except for previously identified AD loci showing stronger association in APOE ε4+ subjects (CR1 and CLU) or APOE ε4- subjects (MS4A6A/MS4A4A/MS4A6E), no other SNPs were significantly associated with AD in a specific APOE genotype subgroup. In addition, the finding in the stage 1 sample that AD risk is significantly influenced by the interaction of APOE with rs1595014 in TMEM106B (P=1·6 × 10-7) is noteworthy, because TMEM106B variants have previously been associated with risk of frontotemporal dementia. Expression quantitative trait locus analysis revealed that rs113986870, one of the GWS SNPs near rs2732703, is significantly associated with four KANSL1 probes that target transcription of the first translated exon and an untranslated exon in hippocampus (P≤1.3 × 10-8), frontal cortex (P≤1.3 × 10-9) and temporal cortex (P≤1.2 × 10-11). Rs113986870 is also strongly associated with a MAPT probe that targets transcription of alternatively spliced exon 3 in frontal cortex (P=9.2 × 10-6) and temporal cortex (P=2.6 × 10-6). Our APOE-stratified GWAS is the first to show GWS association for AD with SNPs in the chromosome 17q21.31 region. Replication of this finding in independent samples is needed to verify that SNPs in this region have significantly stronger effects on AD risk in persons lacking APOE ε4 compared with persons carrying this allele, and if this is found to hold, further examination of this region and studies aimed at deciphering the mechanism(s) are warranted

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/‘proxy’ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/‘proxy’ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele