594 research outputs found
Políticas Públicas e Constituição dos Direitos Educacionais no contexto das práticas curriculares
Anais do 35º Seminário de Extensão Universitária da Região Sul - Área temática: Direitos Humanos e JustiçaEste texto apresenta alguns resultados do Programa de Extensão
Políticas Públicas e Constituição dos Direitos Educacionais no Contexto das Práticas
Curriculares, cujo objetivo foi o de proporcionar espaços de conhecimento, diálogo,
aprendizagens e troca de experiências acerca das políticas públicas e a garantia de
direitos à educação, como reflexo das práticas curriculares em espaços
educacionais formais e não formais. Contou com três ações: a primeira ‘Ciclo de
formação continuada: da gestão educacional as práticas pedagógicas’; a segunda, o
‘Curso A alfabetização e o Estatuto da criança e do Adolescente nas práticas
curriculares na vida escolar’, e, a terceira ação, prevê o Curso a distância: ‘Produção
de material adaptado aos alunos com deficiências: curiosidades da comunicação em
Libras e Braille’, que encontra-se em andamento. Neste trabalho damos ênfase às
duas primeiras ações de extensão, considerando que já encontram-se finalizadas. A
primeira ação nos permitiu discutir e refletir sobre a importância do trabalho
colaborativo, da gestão escolar estar articulada às demandas dos professores e
alunos nos processos de aprendizagens, consequentemente, com a própria
formação profissional que reflete diretamente na formação coletiva e nas relações
humanas. A segunda possibilitou revisitar os planejamentos educacionais e romper
com o pedagógico estático, a partir das interações lúdicas e o brincar, elementos que
foram fundamentais nesse processo de ressignificação dos processos pedagógicos
nos contextos educacionais. Por fim, as interações com os públicos envolvidos,
reforçam a importância das atividades de extensão universitária que tende a
aproximar os conhecimentos acadêmicos com os saberes da comunidade local e
gerar transformações nestes espaço
A LITERATURA INFANTIL EM CONTEXTOS EDUCACIONAIS: RESSIGNIFICANDO OS PROCESSOS PEDAGÓGICOS
A LITERATURA INFANTIL EM CONTEXTOS EDUCACIONAIS:RESSIGNIFICANDO OS PROCESSOS PEDAGÓGICO
A LITERATURA INFANTIL EM CONTEXTOS EDUCACIONAIS: RESSIGNIFICANDO OS PROCESSOS PEDAGÓGICOS
A LITERATURA INFANTIL EM CONTEXTOS EDUCACIONAIS:RESSIGNIFICANDO OS PROCESSOS PEDAGÓGICO
Multifunctional flexible and stretchable electrochromic energy storage devices
Electrochromic energy storage devices (EESDs) including electrochromic supercapacitors (ESC) and electrochromic batteries (ECB) have received significant recent attention in wearables, smart windows, and colour-changing sunglasses due to their multi-functionality, including colour variation under various charge densities. The performance of EESDs is mainly dependent on the properties of three major components (i) the current collector/substrate (cc/substrate) (ii) the electrolyte and (iii) electrochromic materials (ECM). Among various EESDs, advanced flexible or stretchable devices offer better functionality than conventional rigid glass-based devices and are easily integrated with any curved surface. However, in flexible or stretchable EESDs, delamination, dissociation and degradation critically affect the lifecycle and stable performance and are key issues to solve for widespread deployment of the technology. A detailed review of the materials and their performance as flexible EESDs is therefore propitious for the design and engineering of next-generation ECBs and ESCs. In this review, we considered the importance of various materials and their implementation in flexible and stretchable EESD fabrication along with their potential application in sustainable energy systems
High resolution gamma-ray spectrometer with MHz capabilities for runaway electron studies at ASDEX Upgrade
Massively parallel fitness profiling reveals multiple novel enzymes in Pseudomonas putida lysine metabolism
P. putida lysine metabolism can produce multiple commodity chemicals, conferring great biotechnological value. Despite much research, the connection of lysine catabolism to central metabolism in P. putida remained undefined. Here, we used random barcode transposon sequencing to fill the gaps of lysine metabolism in P. putida. We describe a route of 2-oxoadipate (2OA) catabolism, which utilizes DUF1338-containing protein P. putida 5260 (PP_5260) in bacteria. Despite its prevalence in many domains of life, DUF1338-containing proteins have had no known biochemical function. We demonstrate that PP_5260 is a metalloenzyme which catalyzes an unusual route of decarboxylation of 2OA to d-2-hydroxyglutarate (d-2HG). Our screen also identified a recently described novel glutarate metabolic pathway. We validate previous results and expand the understanding of glutarate hydroxylase CsiD by showing that can it use either 2OA or 2KG as a cosubstrate. Our work demonstrated that biological novelty can be rapidly identified using unbiased experimental genetics and that RB-TnSeq can be used to rapidly validate previous results.Despite intensive study for 50 years, the biochemical and genetic links between lysine metabolism and central metabolism in Pseudomonas putida remain unresolved. To establish these biochemical links, we leveraged random barcode transposon sequencing (RB-TnSeq), a genome-wide assay measuring the fitness of thousands of genes in parallel, to identify multiple novel enzymes in both l- and d-lysine metabolism. We first describe three pathway enzymes that catabolize l-2-aminoadipate (l-2AA) to 2-ketoglutarate (2KG), connecting d-lysine to the TCA cycle. One of these enzymes, P. putida 5260 (PP_5260), contains a DUF1338 domain, representing a family with no previously described biological function. Our work also identified the recently described coenzyme A (CoA)-independent route of l-lysine degradation that results in metabolization to succinate. We expanded on previous findings by demonstrating that glutarate hydroxylase CsiD is promiscuous in its 2-oxoacid selectivity. Proteomics of selected pathway enzymes revealed that expression of catabolic genes is highly sensitive to the presence of particular pathway metabolites, implying intensive local and global regulation. This work demonstrated the utility of RB-TnSeq for discovering novel metabolic pathways in even well-studied bacteria, as well as its utility a powerful tool for validating previous research
Modelling of the effect of ELMs on fuel retention at the bulk W divertor of JET
Effect of ELMs on fuel retention at the bulk W target of JET ITER-Like Wall was studied with multi-scale calculations. Plasma input parameters were taken from ELMy H-mode plasma experiment. The energetic intra-ELM fuel particles get implanted and create near-surface defects up to depths of few tens of nm, which act as the main fuel trapping sites during ELMs. Clustering of implantation-induced vacancies were found to take place. The incoming flux of inter-ELM plasma particles increases the different filling levels of trapped fuel in defects. The temperature increase of the W target during the pulse increases the fuel detrapping rate. The inter-ELM fuel particle flux refills the partially emptied trapping sites and fills new sites. This leads to a competing effect on the retention and release rates of the implanted particles. At high temperatures the main retention appeared in larger vacancy clusters due to increased clustering rate
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