Impact of the COVID-19 pandemic on the sexual behavior of the population. The vision of the east and the west

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Deviation from Tri-Bimaximal Mixing and Large Reactor Mixing Angle

Recent observations for a non-zero $\theta_{13}$ have come from various experiments. We study a model of lepton mixing with a 2-3 flavor symmetry to accommodate the sizable $\theta_{13}$ measurement. In this work, we derive deviations from the tri-bimaximal (TBM) pattern arising from breaking the flavor symmetry in the neutrino sector, while the charged leptons contribution has been discussed in a previous work. Contributions from both sectors towards accommodating the non-zero $\theta_{13}$ measurement are presented.Comment: 25 pages, 12 figures. arXiv admin note: text overlap with arXiv:1109.232

Ciencias de la Biología y Agronomía

Este volumen I contiene 17 capítulos arbitrados que se ocupan de estos asuntos en Tópicos Selectos de Ciencias de la Biología y Agronomía, elegidos de entre las contribuciones, reunimos algunos investigadores y estudiantes. Se presenta un Estudio Comparativo de los Recursos Hidrológico-Forestales de la Microcuenca de la Laguna de Epatlan, Pue. (1993 a 2014); la Situación Actual de la Mancha de Asfalto en Maíz (Zea mays L.) en los Municipios de Jiquipilas y Ocozocoautla, Chiapas, México; las poblaciones sobresalientes de maíz de la raza Zapalote Chico, en la Región Istmeña de Oaxaca; Se indica el índice de área foliar de cultivo de Chile Poblano mediante dos métodos en condiciones protegidas; Esquivel, Urzúa y Ramírez exploran el efecto de la biofertilización con Azospirillum en el crecimiento y producción de Jitomate; esbozan su artículo sobre la determinación del nivel de Heterosis en híbridos de Maíz para la Comarca Lagunera; una investigación sobre la estabilización de semilla de Solanum lycopersicum durante el almacenamiento y estimulación de la germinación; acotan sobre el CTAB como una nueva opción para la detección de Huanglongbing en cítricos, plantean su evaluación sobre el aluminio y cómo afecta la vida de florero de Heliconia psittacorum; indican sobre el impacto del H-564C, como un híbrido de maíz con alta calidad de proteina para el trópico húmedo de México; presetan su investigación sobre la producción de Piña Cayena Lisa y MD2 (Ananas comosus L.) en condiciones de Loma Bonita, en Oaxaca; acotan sobre el efecto de coberteras como control biológico por conservación contra áfidos en Nogal Pecanero; esbozan sobre la caracterización de cuatro genotipos de Frijol Negro en Martínez de la Torre, Veracruz, México; presentan una caracterización hidroecológica de la microcuenca de Arroyo Prieto, Yuriría, Gto., y alternativas para su restauración ambiental; presentan su investigación sobre el efecto del hongo Beauveria bassiana sobre solubilización de fosfatos y la disponibilidad de fósforo en el suelo; plantean su investigación sobre la Germinación y regeneración in vitro de Epidendrum falcatum LINDL; esbozan su artículo sobre genotipos de frijol negro y su tolerancia a sequía terminal en Veracruz, México

La hiperplasia benigna de próstata: estudio estereológico e inmunohistoquímico de la proliferación y el número de células, el volumen de los compartimentos prostáticos y la expresión de TGFB1

Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Medicina, Departamento de Morfología. Fecha de lectura: 30 de Junio de 1998

Design of a cost/effective heat exchanger to expand the cooling capacity in the fermentation to ripening racking for Bavaria S.A.

La presente tesis se centró en diseñar un intercambiador de calor costo-efectivo para optimizar la capacidad de enfriamiento durante el proceso de trasiego de fermentación a maduración en la Cervecería Unión, Medellín, perteneciente a la empresa Bavaria. El objetivo principal fue minimizar el tiempo de trasiego de 48 a 10 horas, mediante la implementación de un intercambiador más eficiente y un avanzado sistema de control. Se realizó un detallado estudio del arte y de la técnica para comprender mejor los distintos tipos de intercambiadores y sus características, así como el proceso de fabricación de la cerveza y sus limitantes. Varias alternativas se evaluaron en función de su eficacia y conformidad con las normas técnicas, con especial énfasis en la oferta de Alfa Laval. Los cálculos térmicos indicaron que aumentar el flujo de cerveza de 500 hl/hr a 720 hl/hr y ajustar las temperaturas del proceso permitiría alcanzar el objetivo propuesto. El intercambiador seleccionado demostró un coeficiente global de transferencia de calor de 6421 W/m2K y un área de transferencia de calor de 10.9 m^2, evidenciando una alta eficiencia de transferencia de calor. El diseño mecánico detallado del intercambiador se llevó a cabo, asegurando la solidez y funcionalidad del equipo. El costo total del proyecto, incluyendo inversión inicial y costos operativos, se estimó en 125,349,676 COP. En últimas, a pesar de la inversión inicial y los costos operativos, la implementación de este intercambiador de calor resultará en un aumento significativo en la eficiencia del proceso de producción de cerveza, generando ahorros a largo plazo y mejorando la productividad.This thesis focused on the design of a cost-effective heat exchanger to optimize the cooling capacity during the fermentation to maturation racking process at Cervecería Unión, Medellín, belonging to the Bavaria company. The main objective was to minimize the racking time from 48 to 10 hours by implementing a more efficient exchanger and an advanced control system. A detailed study of the art and technique was conducted to better understand several types of exchangers and their characteristics, as well as the brewing process and its limitations. Several alternatives were evaluated in terms of their efficiency and compliance with technical standards, with special emphasis on Alfa Laval's offering. Thermal calculations indicated that increasing the beer flow rate from 500 hl/hr to 720 hl/hr and adjusting the process temperatures would achieve the proposed objective. The selected exchanger demonstrated an overall heat transfer coefficient of 6421 W/m2K and a heat transfer area of 10.9 m^2, evidencing a high heat transfer efficiency. The detailed mechanical design of the heat exchanger was conducted, ensuring the robustness and functionality of the equipment. The total cost of the project, including initial investment and operating costs, was estimated at COP 125,349,676. Despite the initial investment and operating costs, the implementation of this heat exchanger will result in a significant increase in the efficiency of the beer production process, generating long-term savings and improving productivity

Multicenter Prospective Study of Grafting With Collagen Fleece TachoSil in Patients With Peyronie's Disease.

A xenograft consisting of equine collagen coated with human fibrinogen and thrombin (TachoSil; Baxter, CA) has recently been introduced in grafting procedures for Peyronie's disease (PD). To describe the results of a multicenter prospective registry on patients with PD undergoing plaque incision or and grafting (PIG) or plaque excision and grafting (PEG) with collagen fleece TachoSil, to evaluate the efficacy and safety of this procedure. A prospective non-controlled multicenter study of patients with PD was performed between May 2016 and March 2018. Patients from 10 centers with stable PD for at least 3 months, difficulties in sexual intercourse, normal erectile function with or without pharmacological treatment, curvature >45°, and/or penile shortening and/or complex deformities were included. All patients underwent PIG/PEG with collagen fleece TachoSil. The main outcome measure of this study were penile curvature correction (intraoperative), penile shortening (intraoperative), erectile function with the 5-item version of the International Index of Erectile Function (IIEF-5) and the Erection Hardness Score, subjective patient outcomes with non-validated questionnaires, and complications. A total of 52 patients were enrolled in the study. The mean (SD) preoperative penile curvature was 72.8° (17.0). PIG was the preferred technique (80.8%). Intraoperatively, complete curvature correction was achieved in 92.3%, and no significant penile shortening was recorded in 80.8% of subjects. Subjective penile shortening was reported in 83.3% of patients at 6 months. No objective measurement of penile curvature and length was recorded during follow-up. No statistically significant difference from the baseline was found in IIEF-5 and Erection Hardness Score at 3 or at 6 months, although 16.7% of men experienced a worsening of IIEF-5 scores and 14.3% required de novo phosphodiesterase type 5 inhibitor use. 6 months after surgery, 78.5% of men were satisfied with intervention. Swelling and ecchymosis/hematoma were the most common perioperative complications (40.4%). 2 cases (3.8%) of wound infection were recorded. At 6 months, 35.7% of patients reported mild penile hypesthesia. Our results confirm the high success rate of grafting with TachoSil, and the surgeon perceived low percentage of penile shortening. This is the first multicentre study on patients with PD undergoing grafting with TachoSil without concomitant placement of penile prosthesis. The main limitations are the short follow-up and the relatively small sample size. Grafting with TachoSil after PIG/PEG in patients with PD is an effective and safe procedure. Among the main advantages of this technique, there are ease of use of the graft and reduced operative time. Fernández-Pascual E, Manfredi C, Torremadé J, et al. Multicenter Prospective Study of Grafting With Collagen Fleece TachoSil in Patients With Peyronie's Disease. J Sex Med 2020;17:2279-2286

Multicenter Prospective Study of Grafting With Collagen Fleece TachoSil in Patients With Peyronie's Disease.

Background A xenograft consisting of equine collagen coated with human fibrinogen and thrombin (TachoSil; Baxter, CA) has recently been introduced in grafting procedures for Peyronie’s disease (PD). Aim To describe the results of a multicenter prospective registry on patients with PD undergoing plaque incision or and grafting (PIG) or plaque excision and grafting (PEG) with collagen fleece TachoSil, to evaluate the efficacy and safety of this procedure. Methods A prospective non-controlled multicenter study of patients with PD was performed between May 2016 and March 2018. Patients from 10 centers with stable PD for at least 3 months, difficulties in sexual intercourse, normal erectile function with or without pharmacological treatment, curvature >45°, and/or penile shortening and/or complex deformities were included. All patients underwent PIG/PEG with collagen fleece TachoSil. Outcomes The main outcome measure of this study were penile curvature correction (intraoperative), penile shortening (intraoperative), erectile function with the 5-item version of the International Index of Erectile Function (IIEF-5) and the Erection Hardness Score, subjective patient outcomes with non-validated questionnaires, and complications. Results A total of 52 patients were enrolled in the study. The mean (SD) preoperative penile curvature was 72.8° (17.0). PIG was the preferred technique (80.8%). Intraoperatively, complete curvature correction was achieved in 92.3%, and no significant penile shortening was recorded in 80.8% of subjects. Subjective penile shortening was reported in 83.3% of patients at 6 months. No objective measurement of penile curvature and length was recorded during follow-up. No statistically significant difference from the baseline was found in IIEF-5 and Erection Hardness Score at 3 or at 6 months, although 16.7% of men experienced a worsening of IIEF-5 scores and 14.3% required de novo phosphodiesterase type 5 inhibitor use. 6 months after surgery, 78.5% of men were satisfied with intervention. Swelling and ecchymosis/hematoma were the most common perioperative complications (40.4%). 2 cases (3.8%) of wound infection were recorded. At 6 months, 35.7% of patients reported mild penile hypesthesia. Clinical implications Our results confirm the high success rate of grafting with TachoSil, and the surgeon perceived low percentage of penile shortening. Strength & Limitations This is the first multicentre study on patients with PD undergoing grafting with TachoSil without concomitant placement of penile prosthesis. The main limitations are the short follow-up and the relatively small sample size. Conclusion Grafting with TachoSil after PIG/PEG in patients with PD is an effective and safe procedure. Among the main advantages of this technique, there are ease of use of the graft and reduced operative time.pre-print118 K