441 research outputs found
A sharp image or a sharp knife: norms for the modality-exclusivity of 774 concept-property items
According to recent embodied cognition theories, mental concepts are represented by modality-specific sensory-motor systems. Much of the evidence for modality-specificity in conceptual processing comes from the property-verification task. When applying this and other tasks, it is important to select items based on their modality-exclusivity. We collected modality ratings for a set of 387 properties, each of which was paired with two different concepts, yielding a total of 774 concept-property items. For each item, participants rated the degree to which the property could be experienced through five perceptual modalities (vision, audition, touch, smell, and taste). Based on these ratings, we computed a measure of modality exclusivity, the degree to which a property is perceived exclusively through one sensory modality. In this paper, we briefly sketch the theoretical background of conceptual knowledge, discuss the use of the property-verification task in cognitive research, provide our norms and statistics, and validate the norms in a memory experiment. We conclude that our norms are important for researchers studying modality-specific effects in conceptual processing
Methane release from gas hydrates in the Rock Garden of the Hikurangi margin, New Zealand
Dissolved methane and high resolution bathymetry surveys were conducted over the Rock Garden region of Ritchie Ridge, along the Hikurangi margin, eastern New Zealand. Multibeam bathymetry reveals two prominent, northeast trending ridges, parallel to subduction along the margin, that are steep sided and extensively slumped. Elevated concentrations of methane (up to 10 nM, 10× background) within the water column are associated with a slump structure at the southern end of Eastern Rock Garden. The anomalous methane concentrations were detected by a methane sensor (METS) attached to a conductivity‐temperature‐depth‐optical backscatter device (CTDO) and are associated with elevated light scattering and flare‐shaped backscatter signals revealed by the ship's echo sounder. Increased particulate matter in the water column, possibly related to the seepage and/or higher rates of erosion near slump structures, is considered to be the cause of the increased light scattering, rather than bubbles in the water column. Methane concentrations calculated from the METS are in good agreement with concentrations measured by gas chromatography in water samples collected at the same time. However, there is a c. 20 min (c. 900 m) delay in the METS signal reaching maximum CH4 concentrations. The maximum methane concentration occurs near the plateau of Eastern Rock Garden close to the edge of a slump, at 610 m below sea level (mbsl). This is close to the depth (c. 630 mbsl) where a bottom simulating reflector (BSR) pinches out at the seafloor. Fluctuating water temperatures observed in previous studies indicate that the stability zone for pure methane hydrate in the ocean varies between 630 and 710 mbsl. However, based on calculations of the geothermal gradients from BSRs, we suggest gas hydrate in the study area to be more stable than hydrate from pure methane in sea water, moving the phase boundary in the ocean upward. Small fractions of additional higher order hydrocarbon gases are the most likely cause for increased hydrate stability. Relatively high methane concentrations have been measured down to c. 1000 mbsl, most likely in response to sediment slumping caused by gas hydrate destabilisation of the sediments and/or marking seepage through the gas hydrate zone
Strichartz estimates on Schwarzschild black hole backgrounds
We study dispersive properties for the wave equation in the Schwarzschild
space-time. The first result we obtain is a local energy estimate. This is then
used, following the spirit of earlier work of Metcalfe-Tataru, in order to
establish global-in-time Strichartz estimates. A considerable part of the paper
is devoted to a precise analysis of solutions near the trapping region, namely
the photon sphere.Comment: 44 pages; typos fixed, minor modifications in several place
International ocean discovery program expedition 372 preliminary report: Creeping gas hydrate slides and Hikurangi LWD
International Ocean Discovery Program (IODP) Expedition 372 combined two research topics, slow slip events (SSEs) on subduction faults (IODP Proposal 781A-Full) and actively deforming gas hydrate-bearing landslides (IODP Proposal 841-APL). Our study area on the Hikurangi margin, east of the coast of New Zealand, provided unique locations for addressing both research topics.SSEs at subduction zones are an enigmatic form of creeping fault behavior. They typically occur on subduction zones at depths beyond the capabilities of ocean floor drilling. However, at the northern Hikurangi subduction margin they are among the best-documented and shallowest on Earth. Here, SSEs may extend close to the trench, where clastic and pelagic sediments about 1.0-1.5 km thick overlie the subducting, seamount-studded Hikurangi Plateau. Geodetic data show that these SSEs recur about every 2 years and are associated with measurable seafloor displacement. The northern Hikurangi subduction margin thus provides an excellent setting to use IODP capabilities to discern the mechanisms behind slow slip fault behaviour
The Embodiment of Success and Failure as Forward versus Backward Movements
People often speak of success (e.g., “advance”) and failure (e.g., “setback”) as if they were forward versus backward movements through space. Two experiments sought to examine whether grounded associations of this type influence motor behavior. In Experiment 1, participants categorized success versus failure words by moving a joystick forward or backward. Failure categorizations were faster when moving backward, whereas success categorizations were faster when moving forward. Experiment 2 removed the requirement to categorize stimuli and used a word rehearsal task instead. Even without Experiment 1’s response procedures, a similar cross-over interaction was obtained (e.g., failure memorizations sped backward movements relative to forward ones). The findings are novel yet consistent with theories of embodied cognition and self-regulation
Global well-posedness for a coupled modified kdv system
We prove the sharp global well-posedness result for the initial value problem
(IVP) associated to the system of the modi ed Korteweg-de Vries (mKdV) equation. For
the single mKdV equation such result has been obtained by using Mirura's Transform that
takes the KdV equation to the mKdV equation [8]. We do not know the existence of Miura's
Transform that takes a KdV system to the system we are considering. To overcome this
di culty we developed a new proof of the sharp global well-posedness result for the single
mKdV equation without using Miura's Transform. We could successfully apply this technique
in the case of the mKdV system to obtain the desired result.Fundação para a Ciência e a Tecnologia (FCT
Co-located wind and wave energy farms: Uniformly distributed arrays
publisher: Elsevier articletitle: Co-located wind and wave energy farms: Uniformly distributed arrays journaltitle: Energy articlelink: http://dx.doi.org/10.1016/j.energy.2016.07.069 content_type: article copyright: © 2016 Elsevier Ltd. All rights reserved
Induction of protective and therapeutic anti-pancreatic cancer immunity using a reconstructed MUC1 DNA vaccine
<p>Abstract</p> <p>Background</p> <p>Pancreatic cancer is a common, highly lethal disease with a rising incidence. MUC1 is a tumor-associated antigen that is over-expressed in pancreatic adenocarcinoma. Active immunotherapy that targets MUC1 could have great treatment value. Here we investigated the preventive and therapeutic effect of a MUC1 DNA vaccine on the pancreatic cancer.</p> <p>Methods</p> <p>MUC1-various tandem repeat units(VNTR) DNA vaccine was produced by cloning one repeat of VNTR and inserting the cloned gene into the pcDNA3.1. In the preventive group, female C57BL/6 mice were immunized with the vaccine, pcDNA3.1 or PBS; and challenged with panc02-MUC1 or panc02 cell. In the therapeutic group the mice were challenged with panc02-MUC1 or panc02 cell, and then immunized with the vaccine, pcDNA3.1 or PBS. The tumor size and the survival time of the animals were compared between these groups.</p> <p>Results</p> <p>The DNA vaccine pcDNA3.1-VNTR could raise cytotoxic T lymphocyte (CTL) activity specific for MUC1. In the preventive experiment, the mice survival time was significantly longer in the vaccine group than in the control groups (<it>P </it>< 0.05). In the therapeutic experiment, the DNA vaccine prolonged the survival time of the panc02-MUC1-bearing mice (<it>P </it>< 0.05). In both the preventive and therapeutic experiments, the tumor size was significantly less in the vaccine group than in the control groups (<it>P </it>< 0.05). This pcDNA3.1-VNTR vaccine, however, could not prevent the mice attacked by panc02 cells and had no therapeutic effect on the mice attacked by panc02 cells.</p> <p>Conclusion</p> <p>The MUC1 DNA vaccine pcDNA3.1-VNTR could induce a significant MUC1-specific CTL response; and had both prophylactic and therapeutic effect on panc02-MUC1 tumors. This vaccine might be used as a new adjuvant strategy against pancreatic cancer.</p
Novel word integration in the mental lexicon: Evidence from unmasked and masked semantic priming
- …