70 research outputs found
Posthumous Medical Data Donation: The Case for a Legal Framework
- Author
- Publication venue
- Springer
- Publication date
- 16/01/2019
- Field of study
This article explores the options for establishing a legal framework for posthumous medical data donation (PMDD). This concept has not been discussed in legal scholarship to date at all. The paper is, therefore, a first legal study of PMDD, aiming to address the gap and shed light on the most significant legal issues that could affect this concept. The paper starts by looking at the protection of the deceased’s health records and medical data, finding that this protection in law is more extensive than the general protection of the deceased’s personal data, or the protection of post-mortem privacy as a concept. The paper then investigates key issues around ownership and succession of personal data, including medical and health-related data, and how these could affect PMDD and its legal framework. The author then goes on to explore some parallels with organ donation to determine whether there are some lessons to be learned from this comparable regulatory framework. The paper concludes with the discussion around the need for a Code for posthumous medical data donation developed by the Digital Ethics Lab at the Oxford Internet Institute, and a more formal regime that would enable and facilitate this practice. Here, the author proposes key law reforms in the area of data protection and governance related to PMDD. These reforms would include amendments to the general data protection ideally, to ensure harmonisation and consistency across the EU, as well as between the general and sector-specific data protection laws and policies. These changes would contribute to legal and regulatory clarity and would help implement this important and valuable practice, which aims to facilitate research and advances in medical treatments and care
Introductory programming: a systematic literature review
- Author
- Abu Naser Samy S.
- Agarwal Achla
- Ahmed
- Ahren T. C.
- Al-Jarrah Ahmad
- Alammary Ali
- Annamalai Subashini
- Ayub Mewati
- Badri Suzan
- Bai Yu
- Baird Bridget
- Bandura Albert
- Barlow-Jones Glenda
- Bayliss Jessica D.
- Ben-Ari Mordechai
- Bennedsen Jens
- Bennett Chris
- Berglund Anders
- Berland Matthew
- Briggs Tom
- Bumbacher Engin
- Burch Carl
- Carbonaro Antonella
- Carbone Angela
- Cardell-Oliver Rachel
- Chad Lane H
- Char Bruce
- Charalampos Spyropoulos
- Charles Therese
- Chinn Donald
- Chinn Donald
- Corney Malcolm
- Coull Natalie J
- Crawford Stewart
- Cruz Gilbert
- de Raadt Michael
- de Raadt Michael
- de Raadt Michael
- de Raadt Michael
- de Raadt Michael
- Devey Adrian
- Dickson Paul E.
- Dillon Edward
- Doherty Liam
- Durrheim Mark S.
- D’Souza Daryl
- Eagly Alice H
- Edgcomb Alex
- Edwards Stephen H.
- Falkner Katrina
- Firmalo Fabic Geela Venise
- Fonseca Fred
- Fürst Luka
- Garner Stuart
- Goadrich Mark
- Gonzalez Gracielo
- Gudmundsen Dee
- Haghighi Pari Delir
- Hare Brian K
- Heliotis James
- Hooshyar Danial
- Hovemeyer David
- Hu Minjie
- Hu Minjie
- Hu Yun-Jen
- Huang Chenn-Jung
- Jacqueline
- Jayal Ambikesh
- Jurado Francisco
- Kanaparan Geetha
- Kasto Nadia
- Kiran L.
- Kirby Stephen
- Kitchenham Barbara
- Kouznetsova Svetlana
- Kölling Michael
- LeJeune Noel
- Leska Chuck
- Lipman Derrell
- Lister Raymond
- Lister Raymond
- Lister Raymond
- Lopez Mike
- Lulis Evelyn
- Luoma Harri
- Major L.
- McKeown Jim
- McWhorter William Isaac
- Medley M. Dee
- Mentis Alexander
- Menyhárt László
- Mullins Paul
- Munson Jonathan P.
- Muntha Surya
- Murphy Laurie
- Neto Vicente Lustosa
- Nguyen Thuy-Linh
- Okada Ken
- Orehovački Tihomir
- Orehovački Tihomir
- Palmer James Dean
- Park Myung Ah
- Parsons Dale
- Paul Jody
- Peachock Patrick
- Pearce Janice L.
- Pero Štefan
- Price Kellie
- Quintin
- Rajala Teemu
- Ramli R.Z.
- Ray Andrew
- Rodrigo Maria Mercedes T
- Roels Reinout
- Rountree Janet
- Russo Mark F.
- Sanou Loé
- Schoeffel Pablo
- Schramm Joachim
- Shabalina Olga
- Sharp Jason H
- Sheard Judy
- Sheard Judy
- Shuhidan Shuhaida
- Sindre Guttorm
- Skudder Ben
- Song Hosung
- Sorva Juha
- Sung Kelvin
- Takemura Yasuhiro
- Teague D.
- Teague Donna
- Teague Donna
- Teague Donna
- Teague Donna
- Thompson Errol
- Torrey Lisa
- Truong Nghi
- Vincenti Giovanni
- Wang Hong
- Watkins Kera Z. B.
- Weragama Dinesha
- Whalley Jacqueline
- Whalley Jacqueline
- Whalley Jacqueline
- Whittall S. J.
- Whittinghill David
- Wiebe E
- Wood Krissi
- Yoo Jungsoon P
- Yusri Nurliana
- Publication venue
- 'Association for Computing Machinery (ACM)'
- Publication date
- 01/07/2018
- Field of study
As computing becomes a mainstream discipline embedded in the school curriculum and acts as an enabler for an increasing range of academic disciplines in higher education, the literature on introductory programming is growing. Although there have been several reviews that focus on specific aspects of introductory programming, there has been no broad overview of the literature exploring recent trends across the breadth of introductory programming.
This paper is the report of an ITiCSE working group that conducted a systematic review in order to gain an overview of the introductory programming literature. Partitioning the literature into papers addressing the student, teaching, the curriculum, and assessment, we explore trends, highlight advances in knowledge over the past 15 years, and indicate possible directions for future research
A Contributing Role for Anti-Neuraminidase Antibodies on Immunity to Pandemic H1N1 2009 Influenza A Virus
- Author
- A Jegerlehner
- AC Boon
- Adam Rubrum
- AH Ellebedy
- AP Kendal
- AP Kendal
- AS De Groot
- AS Lipatov
- BE Johansson
- BE Johansson
- BE Johansson
- BE Johansson
- BE Johansson
- BE Johansson
- BE Johansson
- BJ Cowling
- Charles J. Russell
- CY Chi
- D Armerding
- DC Powers
- E Hoffmann
- ED Kilbourne
- EJ Hancock
- F Carrat
- G Marcelin
- Glendie Marcelin
- H Brecht
- H Kayamuro
- I Koerner
- J Katz
- J Steel
- JA Greenbaum
- JA McCullers
- Janet E. McElhaney
- JD Thompson
- JM Song
- K Bragstad
- K Hancock
- K Scheible
- K Sun
- KL Laurie
- KT Holmes
- LJ Reed
- M Mordstein
- MB Pearce
- MR Sandbulte
- MR Sandbulte
- NJ Cox
- PN Pascua
- Q Li
- RA Subbramanian
- Rebecca DuBois
- RG Webster
- Richard J. Webby
- RJ Garten
- S Neirynck
- Tian Wang
- TR Cate
- VJ Lee
- X Xu
- Y Itoh
- Z Chen
- Z Xing
- Publication venue
- Public Library of Science
- Publication date
- 24/10/2011
- Field of study
Exposure to contemporary seasonal influenza A viruses affords partial immunity to pandemic H1N1 2009 influenza A virus (pH1N1) infection. The impact of antibodies to the neuraminidase (NA) of seasonal influenza A viruses to cross-immunity against pH1N1 infection is unknown.Antibodies to the NA of different seasonal H1N1 influenza strains were tested for cross-reactivity against A/California/04/09 (pH1N1). A panel of reverse genetic (rg) recombinant viruses was generated containing 7 genes of the H1N1 influenza strain A/Puerto Rico/08/34 (PR8) and the NA gene of either the pandemic H1N1 2009 strain (pH1N1) or one of the following contemporary seasonal H1N1 strains: A/Solomon/03/06 (rg Solomon) or A/Brisbane/59/07 (rg Brisbane). Convalescent sera collected from mice infected with recombinant viruses were measured for cross-reactive antibodies to pH1N1 via Hemagglutinin Inhibition (HI) or Enzyme-Linked Immunosorbent Assay (ELISA). The ectodomain of a recombinant NA protein from the pH1N1 strain (pNA-ecto) was expressed, purified and used in ELISA to measure cross-reactive antibodies. Analysis of sera from elderly humans immunized with trivalent split-inactivated influenza (TIV) seasonal vaccines prior to 2009 revealed considerable cross-reactivity to pNA-ecto. High titers of cross-reactive antibodies were detected in mice inoculated with either rg Solomon or rg Brisbane. Convalescent sera from mice inoculated with recombinant viruses were used to immunize naïve recipient Balb/c mice by passive transfer prior to challenge with pH1N1. Mice receiving rg California sera were better protected than animals receiving rg Solomon or rg Brisbane sera.The NA of contemporary seasonal H1N1 influenza strains induces a cross-reactive antibody response to pH1N1 that correlates with reduced lethality from pH1N1 challenge, albeit less efficiently than anti-pH1N1 NA antibodies. These findings demonstrate that seasonal NA antibodies contribute to but are not sufficient for cross-reactive immunity to pH1N1
Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- Author
- Abajobir Amanuel Alemu
- Abate Kalkidan Hassen
- Abbafati Cristiana
- Abbas Kaja M.
- Abd-Allah Foad
- Abdulle Abdishakur M.
- Abebo Teshome Abuka
- Abera Semaw Ferede
- Aboyans Victor
- Abu-Raddad Laith J.
- Ackerman Ilana N.
- Adamu Abdu Abdullahi
- Adetokunboh Olatunji
- Afarideh Mohsen
- Afshin Ashkan
- Agarwal Sanjay Kumar
- Aggarwal Rakesh
- Agrawal Anurag
- Agrawal Sutapa
- Ahmad Kiadaliri Aliasghar
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Aiyar Sneha
- Akinyemi Rufus Olusola
- Akseer Nadia
- Al Lami Faris Hasan
- Al-Aly Ziyad
- Al-Maskari Fatma
- Al-Raddadi Rajaa
- Alahdab Fares
- Alam Khurshid
- Alam Noore
- Alam Tahiya
- Alasfoor Deena
- Alene Kefyalew Addis
- Ali Raghib
- Alizadeh-Navaei Reza
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Allen Christine
- Alsharif Ubai
- Alsowaidi Shirina
- Altirkawi Khalid A.
- Amare Azmeraw T.
- Amini Erfan
- Ammar Walid
- Amoako Yaw Ampem
- Andersen Hjalte H.
- Antonio Carl Abelardo T.
- Anwari Palwasha
- Artaman Al
- Aryal Krishna Kumar
- Asayesh Hamid
- Asgedom Solomon W.
- Assadi Reza
- Atey Tesfay Mehari
- Atnafu Niguse Tadele
- Atre Sachin R.
- Avila-Burgos Leticia
- Avokpaho Euripide Frinel G. Arthur
- Awasthi Ashish
- Ayala Quintanilla Beatriz Paulina
- Ba Saleem Huda Omer
- Bacha Umar
- Badawi Alaa
- Balakrishnan Kalpana
- Banerjee Amitava
- Bannick Marlena S.
- Barac Aleksandra
- Barber Ryan M.
- Barker-Collo Suzanne L.
- Barquera Simon
- Barregard Lars
- Barrero Lope H.
- Basu Sanjay
- Battista Bob
- Battle Katherine E.
- Baune Bernhard T.
- Bazargan-Hejazi Shahrzad
- Beardsley Justin
- Bedi Neeraj
- Beghi Ettore
- Bekele Bayu Begashaw
- Bell Michelle L.
- Bennett Derrick A.
- Bensenor Isabela M.
- Benson Jennifer
- Berhane Adugnaw
- Berhe Derbew Fikadu
- Bernabé Eduardo
- Betsu Balem Demtsu
- Beuran Mircea
- Beyene Addisu Shunu
- Bhala Neeraj
- Bhansali Anil
- Bhatt Samir
- Bhutta Zulfiqar A.
- Biadgilign Sibhatu
- Bienhoff Kelly
- Bikbov Boris
- Birungi Charles
- Biryukov Stan
- Bisanzio Donal
- Bizuayehu Habtamu Mellie
- Boneya Dube Jara
- Boufous Soufiane
- Bourne Rupert R.A.
- Brazinova Alexandra
- Brugha Traolach S.
- Buchbinder Rachelle
- Bulto Lemma Negesa Bulto
- Bumgarner Blair R.
- Butt Zahid A.
- Bärnighausen Till
- Béjot Yannick
- Cahuana-Hurtado Lucero
- Cameron Ewan
- Car Mate
- Carabin Hélène
- Carapetis Jonathan R.
- Carpenter David O.
- Carrero Juan Jesus
- Carter Austin
- Carvalho Felix
- Casey Daniel C.
- Caso Valeria
- Castañeda-Orjuela Carlos A.
- Castle Chris D.
- Catalá-López Ferrán
- Chang Hsing-Yi
- Chang Jung-Chen
- Charlson Fiona J.
- Chen Honglei
- Chibalabala Mirriam
- Chibueze Chioma Ezinne
- Chisumpa Vesper Hichilombwe
- Chitheer Abdulaal A.
- Christopher Devasahayam Jesudas
- Ciobanu Liliana G.
- Cirillo Massimo
- Colombara Danny
- Cooper Cyrus
- Cortesi Paolo Angelo
- Criqui Michael H.
- Crump John A.
- Cárdenas Rosario
- Dadi Abel Fekadu
- Dalal Koustuv
- Dandona Lalit
- Dandona Rakhi
- Das Neves José
- Davitoiu Dragos V.
- De Courten Barbora
- De Leo Diego
- Degenhardt Louisa
- Deiparine Selina
- Dellavalle Robert P.
- Deribe Kebede
- Des Jarlais Don C.
- Dey Subhojit
- Dharmaratne Samath D.
- Dhillon Preet Kaur
- Dicker Daniel
- Ding Eric L.
- Djalalinia Shirin
- Do Huyen Phuc
- Dorsey E. Ray
- Dos Santos Kadine Priscila Bender
- Douwes-Schultz Dirk
- Doyle Kerrie E.
- Driscoll Tim R.
- Dubey Manisha
- Duncan Bruce Bartholow
- El-Khatib Ziad Ziad
- Ellerstrand Jerisha
- Enayati Ahmadali
- Endries Aman Yesuf
- Ermakov Sergey Petrovich
- Erskine Holly E.
- Eshrati Babak
- Eskandarieh Sharareh
- Esteghamati Alireza
- Estep Kara
- Fanuel Fanuel Belayneh Bekele
- Farinha Carla Sofia E. Sa
- Faro André
- Farzadfar Farshad
- Fazeli Mir Sohail
- Feigin Valery L.
- Fereshtehnejad Seyed-Mohammad
- Fernandes João C.
- Ferrari Alize J.
- Feyissa Tesfaye Regassa
- Filip Irina
- Fischer Florian
- Fitzmaurice Christina
- Flaxman Abraham D.
- Flor Luisa Sorio
- Foigt Nataliya
- Foreman Kyle J.
- Franklin Richard C.
- Fullman Nancy
- Furtado Joao M.
- Futran Neal D.
- Fürst Thomas
- Gakidou Emmanuela
- Ganji Morsaleh
- Garcia-Basteiro Alberto L.
- Gebre Teshome
- Gebrehiwot Tsegaye Tewelde
- Geleto Ayele
- Gemechu Bikila Lencha
- Gesesew Hailay Abrha
- Gething Peter W.
- Ghajar Alireza
- Gibney Katherine B.
- Gill Paramjit Singh
- Gillum Richard F.
- Ginawi Ibrahim Abdelmageem Mohamed
- Giref Ababi Zergay
- Gishu Melkamu Dedefo
- Giussani Giorgia
- Godwin William W.
- Gold Audra L.
- Goldberg Ellen M.
- Gona Philimon N.
- Goodridge Amador
- Gopalani Sameer Vali
- Goto Atsushi
- Goulart Alessandra Carvalho
- Griswold Max
- Gugnani Harish Chander
- Gupta Rahul
- Gupta Rajeev
- Gupta Tanush
- Gupta Vipin
- Hafezi-Nejad Nima
- Hailu Alemayehu Desalegne
- Hailu Gessessew Bugssa
- Hamadeh Randah Ribhi
- Hamidi Samer
- Handal Alexis J.
- Hankey Graeme J.
- Hao Yuantao
- Harb Hilda L.
- Hareri Habtamu Abera
- Haro Josep Maria
- Harvey James
- Hassanvand Mohammad Sadegh
- Havmoeller Rasmus
- Hawley Caitlin
- Hay Roderick J.
- Hay Simon I.
- Henry Nathaniel J.
- Heredia-Pi Ileana Beatriz
- Hernandez Julio Montañez
- Heydarpour Pouria
- Hoek Hans W.
- Hoffman Howard J.
- Horita Nobuyuki
- Hosgood H. Dean
- Hostiuc Sorin
- Hotez Peter J.
- Hoy Damian G.
- Htet Aung Soe
- Hu Guoqing
- Huang Hsiang
- Huynh Chantal
- Iburg Kim Moesgaard
- Igumbor Ehimario Uche
- Ikeda Chad
- Irvine Caleb Mackay Salpeter
- Jacobsen Kathryn H.
- Jahanmehr Nader
- Jakovljevic Mihajlo B.
- Jassal Simerjot K.
- Javanbakht Mehdi
- Jayaraman Sudha P.
- Jeemon Panniyammakal
- Jensen Paul N.
- Jha Vivekanand
- Jiang Guohong
- John Denny
- Johnson Catherine O.
- Johnson Sarah Charlotte
- Jonas Jost B.
- Jürisson Mikk
- Kabir Zubair
- Kadel Rajendra
- Kahsay Amaha
- Kamal Ritul
- Kan Haidong
- Karam Nadim E.
- Karch André
- Karema Corine Kakizi
- Kasaeian Amir
- Kassa Getachew Mullu
- Kassaw Nigussie Assefa
- Kassebaum Nicholas J.
- Kastor Anshul
- Katikireddi Srinivasa Vittal
- Kaul Anil
- Kawakami Norito
- Keiyoro Peter Njenga
- Kengne Andre Pascal
- Keren Andre
- Khader Yousef Saleh
- Khalil Ibrahim A.
- Khan Ejaz Ahmad
- Khang Young-Ho
- Khosravi Ardeshir
- Khubchandani Jagdish
- Kieling Christian
- Kim Daniel
- Kim Pauline
- Kim Yun Jin
- Kimokoti Ruth W.
- Kinfu Yohannes
- Kisa Adnan
- Kissimova-Skarbek Katarzyna A.
- Kivimaki Mika
- Knudsen Ann Kristin
- Kokubo Yoshihiro
- Kolte Dhaval
- Kopec Jacek A.
- Kosen Soewarta
- Koul Parvaiz A.
- Koyanagi Ai
- Kravchenko Michael
- Krishnaswami Sanjay
- Krohn Kristopher J.
- Kuate Defo Barthelemy
- Kucuk Bicer Burcu
- Kumar G. Anil
- Kumar Pushpendra
- Kumar Sanjiv
- Kyu Hmwe H.
- Lal Dharmesh Kumar
- Lalloo Ratilal
- Lambert Nkurunziza
- Lan Qing
- Larsson Anders
- Lavados Pablo M.
- Leasher Janet L.
- Lee Jong-Tae
- Lee Paul H.
- Leigh James
- Leshargie Cheru Tesema
- Leung Janni
- Leung Ricky
- Levi Miriam
- Li Kappe Darya
- Li Yichong
- Li Yongmei
- Liang Xiaofeng
- Liben Misgan Legesse
- Lim Stephen S.
- Linn Shai
- Liu Angela
- Liu Patrick Y.
- Liu Shiwei
- Liu Yang
- Lodha Rakesh
- Logroscino Giancarlo
- London Stephanie J.
- Looker Katharine J.
- Lopez Alan D.
- Lorkowski Stefan
- Lotufo Paulo A.
- Low Nicola
- Lozano Rafael
- Lucas Timothy C.D.
- Macarayan Erlyn Rachelle King
- Magdy Abd El Razek Hassan
- Magdy Abd El Razek Mohammed
- Mahdavi Mahdi
- Majdan Marek
- Majdzadeh Reza
- Majeed Azeem
- Malekzadeh Reza
- Malhotra Rajesh
- Malta Deborah Carvalho
- Mamun Abdullah A.
- Manguerra Helena
- Manhertz Treh
- Mantilla Ana
- Mantovani Lorenzo G.
- Mapoma Chabila C.
- Marczak Laurie B.
- Martinez-Raga Jose
- Martins-Melo Francisco Rogerlândio
- Martopullo Ira
- Mathur Manu Raj
- Mazidi Mohsen
- McAlinden Colm
- McGaughey Madeline
- McGrath John J.
- McKee Martin
- McNellan Claire
- Mehata Suresh
- Mehndiratta Man Mohan
- Mekonnen Tefera Chane
- Memiah Peter
- Memish Ziad A.
- Mendoza Walter
- Mengistie Mubarek Abera
- Mengistu Desalegn Tadese
- Mensah George A.
- Meretoja Atte
- Meretoja Tuomo J.
- Mezgebe Haftay Berhane
- Micha Renata
- Millear Anoushka
- Miller Ted R.
- Mills Edward J.
- Mirarefin Mojde
- Mirrakhimov Erkin M.
- Misganaw Awoke
- Mishra Shiva Raj
- Mitchell Philip B.
- Mohammad Karzan Abdulmuhsin
- Mohammadi Alireza
- Mohammed Kedir Endris
- Mohammed Shafiu
- Mohanty Sanjay K.
- Mokdad Ali H.
- Mollenkopf Sarah K.
- Monasta Lorenzo
- Montico Marcella
- Moradi-Lakeh Maziar
- Moraga Paula
- Mori Rintaro
- Morozoff Chloe
- Morrison Shane D.
- Moses Mark
- Mountjoy-Venning Cliff
- Mruts Kalayu Birhane
- Mueller Ulrich O.
- Muller Kate
- Murdoch Michele E.
- Murray Christopher J.L.
- Murthy Gudlavalleti Venkata Satyanarayana
- Musa Kamarul Imran
- März Winfried
- Nachega Jean B.
- Nagel Gabriele
- Naghavi Mohsen
- Naheed Aliya
- Naidoo Kovin S.
- Naldi Luigi
- Nangia Vinay
- Natarajan Gopalakrishnan
- Negasa Dumessa Edessa
- Negoi Ionut
- Negoi Ruxandra Irina
- Newton Charles R.
- Ngunjiri Josephine Wanjiku
- Nguyen Cuong Tat
- Nguyen Grant
- Nguyen Minh
- Nguyen Quyen Le
- Nguyen Trang Huyen
- Nichols Emma
- Ningrum Dina Nur Anggraini
- Nolte Sandra
- Nong Vuong Minh
- Norrving Bo
- Noubiap Jean Jacques N.
- O'Donnell Martin J.
- Ogbo Felix Akpojene
- Oh In-Hwan
- Okoro Anselm
- Oladimeji Olanrewaju
- Olagunju Andrew Toyin
- Olagunju Tinuke Oluwasefunmi
- Olsen Helen E.
- Olusanya Bolajoko Olubukunola
- Olusanya Jacob Olusegun
- Ong Kanyin
- Opio John Nelson
- Oren Eyal
- Ortiz Alberto
- Osgood-Zimmerman Aaron
- Osman Majdi
- Owolabi Mayowa O.
- Pa Mahesh
- Pacella Rosana E.
- Pana Adrian
- Panda Basant Kumar
- Papachristou Christina
- Park Eun-Kee
- Parry Charles D.
- Parsaeian Mahboubeh
- Patten Scott B.
- Patton George C.
- Paulson Katherine
- Pearce Neil
- Pereira David M.
- Perico Norberto
- Pesudovs Konrad
- Peterson Carrie Beth
- Petzold Max
- Phillips Michael Robert
- Pigott David M.
- Pillay Julian David
- Pinho Christine
- Plass Dietrich
- Pletcher Martin A.
- Popova Svetlana
- Poulton Richie G.
- Pourmalek Farshad
- Prabhakaran Dorairaj
- Prasad Narayan
- Prasad Noela M.
- Purcell Carrie
- Qorbani Mostafa
- Quansah Reginald
- Rabiee Rynaz H.S.
- Radfar Amir
- Rafay Anwar
- Rahimi Kazem
- Rahimi-Movaghar Afarin
- Rahimi-Movaghar Vafa
- Rahman Mahfuzar
- Rahman Mohammad Hifz Ur
- Rai Rajesh Kumar
- Rajsic Sasa
- Ram Usha
- Ranabhat Chhabi Lal
- Rankin Zane
- Rao Paturi Vishnupriya
- Rao Puja C.
- Rawaf Salman
- Ray Sarah E.
- Reiner Robert C.
- Reinig Nikolas
- Reitsma Marissa B.
- Remuzzi Giuseppe
- Renzaho Andre M.N.
- Resnikoff Serge
- Rezaei Satar
- Ribeiro Antonio L.
- Ronfani Luca
- Roshandel Gholamreza
- Roth Gregory A.
- Roy Ambuj
- Rubagotti Enrico
- Ruhago George Mugambage
- Saadat Soheil
- Sadat Nafis
- Safdarian Mahdi
- Safi Sare
- Safiri Saeid
- Sagar Rajesh
- Sahathevan Ramesh
- Salama Joseph
- Salomon Joshua A.
- Salvi Sundeep Santosh
- Samy Abdallah M.
- Sanabria Juan R.
- Santomauro Damian
- Santos Itamar S.
- Santos João Vasco
- Santric Milicevic Milena M.
- Sartorius Benn
- Satpathy Maheswar
- Sawhney Monika
- Saxena Sonia
- Schmidt Maria Inês
- Schneider Ione J.C.
- Schwebel David C.
- Schwendicke Falk
- Schöttker Ben
- Seedat Soraya
- Sepanlou Sadaf G.
- Servan-Mori Edson E.
- Setegn Tesfaye
- Shackelford Katya Anne
- Shaheen Amira
- Shaikh Masood Ali
- Shamsipour Mansour
- Shariful Islam Sheikh Mohammed
- Sharma Jayendra
- Sharma Rajesh
- She Jun
- Shi Peilin
- Shields Chloe
- Shigematsu Mika
- Shinohara Yukito
- Shiri Rahman
- Shirkoohi Reza
- Shirude Shreya
- Shishani Kawkab
- Shrime Mark G.
- Sibai Abla Mehio
- Sigfusdottir Inga Dora
- Silva Diego Augusto Santos
- Silva João Pedro
- Silveira Dayane Gabriele Alves
- Singh Jasvinder A.
- Singh Narinder Pal
- Sinha Dhirendra Narain
- Skiadaresi Eirini
- Skirbekk Vegard
- Slepak Erica Leigh
- Sligar Amber
- Smith David L.
- Smith Mari
- Sobaih Badr H.A.
- Sobngwi Eugene
- Sorensen Reed J.D.
- Sousa Tatiane Cristina Moraes
- Sposato Luciano A.
- Sreeramareddy Chandrashekhar T.
- Srinivasan Vinay
- Stanaway Jeffrey D.
- Stathopoulou Vasiliki
- Steel Nicholas
- Stein Dan J.
- Stein Murray B.
- Steiner Caitlyn
- Steiner Timothy J.
- Steinke Sabine
- Stokes Mark Andrew
- Stovner Lars Jacob
- Strub Bryan
- Subart Michelle
- Sufiyan Muawiyyah Babale
- Suliankatchi Abdulkader Rizwan
- Sunguya Bruno F.
- Sur Patrick J.
- Swaminathan Soumya
- Sykes Bryan L.
- Sylte Dillon O.
- Tabarés-Seisdedos Rafael
- Taffere Getachew Redae
- Takala Jukka S.
- Tandon Nikhil
- Tavakkoli Mohammad
- Taveira Nuno
- Taylor Hugh R.
- Tehrani-Banihashemi Arash
- Tekelab Tesfalidet
- Temam Shifa Girma
- Terkawi Abdullah Sulieman
- Tesfaye Dawit Jember
- Tesssema Belay
- Thamsuwan Ornwipa
- Thomas Katie E.
- Thrift Amanda G.
- Tiruye Tenaw Yimer
- Tobe-Gai Ruoyan
- Tollanes Mette C.
- Tonelli Marcello
- Topor-Madry Roman
- Tortajada Miguel
- Touvier Mathilde
- Tran Bach Xuan
- Tripathi Suryakant
- Troeger Christopher
- Truelsen Thomas
- Tsoi Derrick
- Tuem Kald Beshir
- Tuzcu Emin Murat
- Tyrovolas Stefanos
- Ukwaja Kingsley N.
- Undurraga Eduardo A.
- Uneke Chigozie Jesse
- Updike Rachel
- Uthman Olalekan A.
- Uzochukwu Benjamin S. Chudi
- Van Boven Job F.M.
- Varughese Santosh
- Vasankari Tommi
- Venkatesh
- Venketasubramanian Narayanaswamy
- Vidavalur Ramesh
- Violante Francesco S.
- Vladimirov Sergey K.
- Vlassov Vasiliy Victorovich
- Vollset Stein Emil
- Vos Theo
- Wadilo Fiseha
- Wakayo Tolassa
- Wang Yuan-Pang
- Weaver Marcia
- Weichenthal Scott
- Weiderpass Elisabete
- Weintraub Robert G.
- Werdecker Andrea
- Westerman Ronny
- Whiteford Harvey A.
- Wijeratne Tissa
- Wiysonge Charles Shey
- Wolfe Charles D.A.
- Woodbrook Rachel
- Woolf Anthony D.
- Workicho Abdulhalik
- Wulf Hanson Sarah
- Xavier Denis
- Xu Gelin
- Yadgir Simon
- Yaghoubi Mohsen
- Yakob Bereket
- Yan Lijing L.
- Yano Yuichiro
- Ye Pengpeng
- Yimam Hassen Hamid
- Yip Paul
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z.
- Zaidi Zoubida
- Zaki Maysaa El Sayed
- Zegeye Elias Asfaw
- Zenebe Zerihun Menlkalew
- Zhang Xueying
- Zhou Maigeng
- Zipkin Ben
- Zodpey Sanjay
- Zuhlke Liesl Joanna
- Ärnlöv Johan
- Publication venue
- Publication date
- 01/01/2017
- Field of study
As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016
Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- Author
- Abajobir Amanuel Alemu
- Abate Kalkidan Hassen
- Abbafati Cristiana
- Abbas Kaja M.
- Abd-Allah Foad
- Abdulkader Rizwan Suliankatchi
- Abdulle Abdishakur M.
- Abebo Teshome Abuka
- Abera Semaw Ferede
- Aboyans Victor
- Abu-Raddad Laith J.
- Ackerman Ilana N.
- Adedeji Isaac A.
- Adedji
- Adetokunboh Olatunji
- Afshin Ashkan
- Aggarwal Rakesh
- Agrawal Anurag
- Agrawal Sutapa
- Ahmed Muktar Beshir
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Aiyar Sneha
- Akinyemiju Tomi F.
- Akseer Nadia
- Al Lami Faris Hasan
- Al-Aly Ziyad
- Al-Maskari Fatma
- Al-Raddadi Rajaa
- Alahdab Fares
- Alam Khurshid
- Alam Noore
- Alam Tahiya
- Alasfoor Deena
- Alene Kefyalew Addis
- Ali Raghib
- Alizadeh-Navaei Reza
- Alkaabi Juma M.
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Allen Christine
- Almazroa Mohammad Abdulaziz
- Alsharif Ubai
- Alsowaidi Shirina
- Althouse Benjamin M.
- Altirkawi Khalid A.
- Alvis-Guzman Nelson
- Amare Azmeraw T.
- Amini Erfan
- Ammar Walid
- Amoako Yaw Ampem
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T.
- Anwari Palwasha
- Arora Megha
- Artaman Al
- Arthur Avokpaho Euripide Frinel G.
- Aryal Krishna Kumar
- Asgedom Solomon W.
- Atey Tesfay Mehari
- Atnafu Niguse Tadele
- Avila-Burgos Leticia
- Awasthi Ashish
- Awasthi Shally
- Azarpazhooh Mahmoud Reza
- Azzopardi Peter
- Babalola Tesleem Kayode
- Bacha Umar
- Badawi Alaa
- Balakrishnan Kalpana
- Bannick Marlena S.
- Barac Aleksandra
- Barker-Collo Suzanne L.
- Barquera Simon
- Barrero Lope H.
- Basu Sanjay
- Battista Robert
- Battle Katherine E.
- Baune Bernhard T.
- Bazargan-Hejazi Shahrzad
- Beardsley Justin
- Bedi Neeraj
- Bekele Bayu Begashaw
- Bell Michelle L.
- Bennett Derrick A.
- Bennett James R.
- Bensenor Isabela M.
- Benson Jennifer
- Berhane Adugnaw
- Berhe Derbew Fikadu
- Bernabé Eduardo
- Betsu Balem Demtsu
- Beuran Mircea
- Beyene Addisu Shunu
- Bhansali Anil
- Bhatt Samir
- Bhutta Zulfqar A.
- Biadgilign Sibhatu
- Bicer Burcu Kucuk
- Bienhof Kelly
- Bikbov Boris
- Birungi Charles
- Biryukov Stan
- Bisanzio Donal
- Bizuayehu Habtamu Mellie
- Blyth Fiona M.
- Boneya Dube Jara
- Bose Dipan
- Bou-Orm Ibrahim R.
- Bourne Rupert R. A.
- Brainin Michael
- Brayne Carol E. G.
- Brazinova Alexandra
- Breitborde Nicholas J. K.
- Briant Paul S.
- Britton Gabrielle
- Brugha Traolach S.
- Bryane
- Buchbinder Rachelle
- Bulto Lemma Negesa Bulto
- Bumgarner Blair
- Butt Zahid A.
- Bärnighausen Till
- Béjot Yannick
- Cahuana-Hurtado Lucero
- Cameron Ewan
- Campos-Nonato Ismael Ricardo
- Carabin Hélène
- Carpenter David O.
- Carrero Juan Jesus
- Carter Austin
- Carvalho Felix
- Casey Daniel
- Castañeda-Orjuela Carlos A.
- Castle Chris D.
- Catalá-López Ferrán
- Chang Jung-Chen
- Charlson Fiona J.
- Chaturvedi Pankaj
- Chen Honglei
- Chibalabala Mirriam
- Chibueze Chioma Ezinne
- Chisumpa Vesper Hichilombwe
- Chitheer Abdulaal A.
- Chowdhury Rajiv
- Christopher Devasahayam Jesudas
- Ciobanu Liliana G.
- Cirillo Massimo
- Colombara Danny
- Cooper Cyrus
- Cooper Leslie Trumbull
- Cortesi Paolo Angelo
- Cortinovis Monica
- Criqui Michael H.
- Cromwell Elizabeth A.
- Cross Marita
- Crump John A.
- Cárdenas Rosario
- Dadi Abel Fekadu
- Dalal Koustuv
- Damasceno Albertino
- Dandona Lalit
- Dandona Rakhi
- Das Jarlais Don C.
- Das Neves José
- Davitoiu Dragos V.
- Davletov Kairat
- De Courten Barbora
- De Leo Diego
- De Steur Hans
- Defo Barthelemy Kuate
- Degenhardt Louisa
- Deiparine Selina
- Dellavalle Robert P.
- Deribe Kebede
- Deribew Amare
- Dey Subhojit
- Dharmaratne Samath D.
- Dhillon Preet K.
- Dicker Daniel
- Djalalinia Shirin
- Do Huyen Phuc
- Dokova Klara
- Doku David Teye
- Dorsey E. Ray
- Dos Santos Kadine Priscila Bender
- Driscoll Tim R.
- Dubey Manisha
- Duncan Bruce Bartholow
- Ebel Beth E.
- Echko Michelle
- El-Khatib Ziad Ziad
- Enayati Ahmadali
- Endries Aman Yesuf
- Ermakov Sergey Petrovich
- Erskine Holly E.
- Eshetie Setegn
- Eshrati Babak
- Esteghamati Alireza
- Estep Kara
- Fanuel Fanuel Belayneh Bekele
- Farag Tamer
- Farinha Carla Sofa E Sa
- Faro André
- Farzadfar Farshad
- Fazeli Mir Sohail
- Feigin Valery L.
- Feigl Andrea B.
- Fereshtehnejad Seyed-Mohammad
- Fernandes João C.
- Ferrari Alize J.
- Feyissa Tesfaye Regassa
- Filip Irina
- Fischer Florian
- Fitzmaurice Christina
- Flaxman Abraham D.
- Foigt Nataliya
- Foreman Kyle J.
- Franklin Richard C.
- Frostad Joseph J.
- Fullman Nancy
- Furtado Joao M.
- Futran Neal D.
- Fürst Thomas
- Gakidou Emmanuela
- Garcia-Basteiro Alberto L.
- Gebre Teshome
- Gebregergs Gebremedhin Berhe
- Gebrehiwot Tsegaye Tewelde
- Geleijnse Johanna M.
- Geleto Ayele
- Gemechu Bikila Lencha
- Gesesew Hailay Abrha
- Gething Peter W.
- Ghajar Alireza
- Gibney Katherine B.
- Gillum Richard F.
- Ginawi Ibrahim Abdelmageem Mohamed
- Gishu Melkamu Dedefo
- Giussani Giorgia
- Godwin William W.
- Goel Kashish
- Goenka Shifalika
- Goldberg Ellen M.
- Gona Philimon N.
- Goodridge Amador
- Gopalani Sameer Vali
- Gosselin Richard A.
- Gotay Carolyn C.
- Goto Atsushi
- Goulart Alessandra Carvalho
- Graetz Nicholas
- Gugnani Harish Chander
- Gupta Prakash C.
- Gupta Rahul
- Gupta Rajeev
- Gupta Tanush
- Gupta Vipin
- Gutiérrez Reyna A.
- Hachinski Vladimir
- Hafezi-Nejad Nima
- Hailu Alemayehu Desalegne
- Hailu Gessessew Bugssa
- Hamadeh Randah Ribhi
- Hamidi Samer
- Hammami Mouhanad
- Handal Alexis J.
- Hankey Graeme J.
- Hao Yuantao
- Harb Hilda L.
- Hareri Habtamu Abera
- Haro Josep Maria
- Harun Kimani M.
- Harvey James
- Hassanvand Mohammad Sadegh
- Havmoeller Rasmus
- Hay Roderick J.
- Hay Simon I.
- Hedayati Mohammad T.
- Hendrie Delia
- Henry Nathaniel J.
- Heredia-Pi Ileana Beatriz
- Heydarpour Pouria
- Hoek Hans W.
- Hofman Howard J.
- Horino Masako
- Horita Nobuyuki
- Hosgood H. Dean
- Hostiuc Sorin
- Hotez Peter J.
- Hoy Damian G.
- Htet Aung Soe
- Hu Guoqing
- Huang John J.
- Huynh Chantal
- Iburg Kim Moesgaard
- Igumbor Ehimario Uche
- Ikeda Chad
- Irvine Caleb Mackay Salpeter
- Jacobsen Kathryn H.
- Jahanmehr Nader
- Jakovljevic Mihajlo B.
- James Peter
- Jassal Simerjot K.
- Javanbakht Mehdi
- Jayaraman Sudha P.
- Jeemon Panniyammakal
- Jensen Paul N.
- Jha Vivekanand
- Jiang Guohong
- John Denny
- Johnson Catherine O.
- Johnson Sarah Charlotte
- Jonas Jost B.
- Jürisson Mikk
- Kabir Zubair
- Kadel Rajendra
- Kahsay Amaha
- Kamal Ritul
- Kar Chittaranjan
- Karam Nadim E.
- Karch André
- Karema Corine Kakizi
- Karimi Seyed M.
- Karimkhani Chante
- Kasaeian Amir
- Kassa Getachew Mullu
- Kassaw Nigussie Assefa
- Kassebaum Nicholas J.
- Kastor Anshul
- Katikireddi Srinivasa Vittal
- Kaul Anil
- Kawakami Norito
- Keiyoro Peter Njenga
- Kemmer Laura
- Kengne Andre Pascal
- Keren Andre
- Kesavachandran Chandrasekharan Nair
- Khader Yousef Saleh
- Khalil Ibrahim A.
- Khan Ejaz Ahmad
- Khang Young-Ho
- Khoja Abdullah T.
- Khosravi Ardeshir
- Khubchandani Jagdish
- Kiadaliri Aliasghar Ahmad
- Kieling Christian
- Kim Daniel
- Kim Yun Jin
- Kimokoti Ruth W.
- Kinfu Yohannes
- Kisa Adnan
- Kissimova-Skarbek Katarzyna A.
- Kissoon Niranjan
- Kivimaki Mika
- Knudsen Ann Kristin
- Kokubo Yoshihiro
- Kolte Dhaval
- Kopec Jacek A.
- Kosen Soewarta
- Kotsakis Georgios A.
- Koul Parvaiz A.
- Koyanagi Ai
- Kravchenko Michael
- Krohn Kristopher J.
- Kumar G. Anil
- Kumar Pushpendra
- Kyu Hmwe H.
- Lager Anton Carl Jonas
- Lal Dharmesh Kumar
- Lalloo Ratilal
- Lallukka Tea
- Lambert Nkurunziza
- Lan Qing
- Lansingh Van C.
- Larsson Anders
- Leasher Janet L.
- Lee Paul H.
- Leigh James
- Leshargie Cheru Tesema
- Leung Janni
- Leung Ricky
- Levi Miriam
- Li Yichong
- Li Yongmei
- Liang Xiaofeng
- Liben Misgan Legesse
- Lim Stephen S.
- Linn Shai
- Liu Angela
- Liu Patrick Y.
- Liu Shiwei
- Liu Yang
- Lodha Rakesh
- Logroscino Giancarlo
- Looker Katharine J.
- Lopez Alan D.
- Lorkowski Stefan
- Lotufo Paulo A.
- Lozano Rafael
- Lucas Timothy C. D.
- Lunevicius Raimundas
- Lyons Ronan A.
- Macarayan Erlyn Rachelle King
- Maddison Emilie R.
- Magdy Abd El Razek Hassan
- Magdy Abd El Razek Mohammed
- Magis-Rodriguez Carlos
- Mahdavi Mahdi
- Majdan Marek
- Majdzadeh Reza
- Majeed Azeem
- Malekzadeh Reza
- Malhotra Rajesh
- Malta Deborah Carvalho
- Mamun Abdullah A.
- Manguerra Helena
- Manhertz Treh
- Mantovani Lorenzo G.
- Mapoma Chabila C.
- March Lyn M.
- Marczak Laurie B.
- Martinez-Raga Jose
- Martins Paulo Henrique Viegas
- Martins-Melo Francisco Rogerlândio
- Martopullo Ira
- Mathur Manu Raj
- Mazidi Mohsen
- McAlinden Colm
- McGaughey Madeline
- McGrath John J.
- McKee Martin
- Mehata Suresh
- Meier Toni
- Meles Kidanu Gebremariam
- Memiah Peter
- Memish Ziad A.
- Mendoza Walter
- Mengesha Melkamu Merid
- Mengistie Mubarek Abera
- Mengistu Desalegn Tadese
- Mensah George A.
- Meretoja Atte
- Meretoja Tuomo J.
- Mezgebe Haftay Berhane
- Micha Renata
- Millear Anoushka
- Miller Ted R.
- Minnig Shawn
- Mirarefn Mojde
- Mirrakhimov Erkin M.
- Misganaw Awoke
- Mishra Shiva Raj
- Mitchell Philip B.
- Mohammad Karzan Abdulmuhsin
- Mohammadi Alireza
- Mohammed Kedir Endris
- Mohammed Muktar Sano Kedir
- Mohammed Shafu
- Mohan Murali B. V.
- Mokdad Ali H.
- Mollenkopf Sarah K.
- Monasta Lorenzo
- Montañez Hernandez Julio Cesar
- Montico Marcella
- Moradi-Lakeh Maziar
- Moraga Paula
- Morawska Lidia
- Mori Rintaro
- Morrison Shane D.
- Moses Mark
- Mountjoy-Venning Clif
- Mruts Kalayu Birhane
- Mudoch Michele E.
- Mueller Ulrich O.
- Muller Kate
- Murdoch
- Murray Christopher J. L.
- Murthy Gudlavalleti Venkata Satyanarayana
- Murthy Srinivas
- Musa Kamarul Imran
- März Winfried
- Nachega Jean B.
- Nagel Gabriele
- Naghavi Mohsen
- Naheed Aliya
- Naidoo Kovin S.
- Nangia Vinay
- Nasher Jamal T.
- Natarajan Gopalakrishnan
- Negasa Dumessa Edessa
- Negoi Ionut
- Negoi Ruxandra Irina
- Newton Charles R.
- Ngunjiri Josephine Wanjiku
- Nguyen Cuong Tat
- Nguyen Grant
- Nguyen Minh
- Nguyen Quyen Le
- Nguyen Trang Huyen
- Nichols Emma
- Ningrum Dina Nur Anggraini
- Nong Vuong Minh
- Norheim Ole F.
- Norrving Bo
- Noubiap Jean Jacques N.
- Nyandwi Alypio
- O'Donnell Martin J.
- Obermeyer Carla Makhlouf
- Ogbo Felix Akpojene
- Oh In-Hwan
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- Oladimeji Olanrewaju
- Olagunju Andrew Toyin
- Olagunju Tinuke Oluwasefunmi
- Olsen Helen E.
- Olusanya Bolajoko Olubukunola
- Olusanya Jacob Olusegun
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- Opio John Nelson
- Oren Eyal
- Ortiz Alberto
- Osborne Richard H.
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- Osman Majdi
- Ota Erika
- Owolabi Mayowa O.
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- Pacella Rosana E.
- Panda Basant Kumar
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- Papachristou Christina
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- Patton George C.
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- Perico Norberto
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- Purwar Manorama
- Qorbani Mostafa
- Quintanilla Beatriz Paulina Ayala
- Rabiee Rynaz H. S.
- Radfar Amir
- Rafay Anwar
- Rahimi Kazem
- Rahimi-Movaghar Afarin
- Rahimi-Movaghar Vafa
- Rahman Mahfuzar
- Rahman Mohammad Hifz Ur
- Rahman Muhammad Aziz
- Rai Rajesh Kumar
- Rajsic Sasa
- Ram Usha
- Ranabhat Chhabi Lal
- Rangaswamy Thara
- Rankin Zane
- Rao Paturi Vishnupriya
- Rao Puja C.
- Rawaf Salman
- Ray Sarah E.
- Reiner Robert C.
- Reinig Nikolas
- Reitsma Marissa
- Remuzzi Giuseppe
- Renzaho Andre M. N.
- Resnikof Serge
- Rezaei Satar
- Ribeiro Antonio L.
- Rivas Jacqueline Castillo
- Roba Hirbo Shore
- Robinson Stephen R.
- Rojas-Rueda David
- Rokni Mohammad Bagher
- Ronfani Luca
- Roshandel Gholamreza
- Roth Gregory A.
- Rothenbacher Dietrich
- Roy Ambuj
- Rubagotti Enrico
- Ruhago George Mugambage
- Saadat Soheil
- Safdarian Mahdi
- Safri Saeid
- Sagar Rajesh
- Sahathevan Ramesh
- Sahraian Mohammad Ali
- Salama Joseph
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- Salomon Joshua A.
- Salvi Sundeep Santosh
- Samy Abdallah M.
- Sanabria Juan Ramon
- Sanchez-Niño Maria Dolores
- Santomauro Damian
- Santos Itamar S.
- Santos João Vasco
- Santric Milicevic Milena M.
- Sartorius Benn
- Satpathy Maheswar
- Sawhney Monika
- Saxena Sonia
- Schelonka Kathryn
- Schmidt Maria Inês
- Schneider Ione J. C.
- Schutte Aletta E.
- Schwebel David C.
- Schwendicke Falk
- Schöttker Ben
- Seedat Soraya
- Sepanlou Sadaf G.
- Servan-Mori Edson E.
- Shaheen Amira
- Shaikh Masood Ali
- Shamsipour Mansour
- Shariful Islam Sheikh Mohammed
- Sharma Jayendra
- Sharma Rajesh
- She Jun
- Shi Peilin
- Shibuya Kenji
- Shields Chloe
- Shiferaw Mekonnen Sisay
- Shigematsu Mika
- Shiri Rahman
- Shirkoohi Reza
- Shirude Shreya
- Shishani Kawkab
- Shoman Haitham
- Siabani Soraya
- Sibai Abla Mehio
- Sigfusdottir Inga Dora
- Silberberg Donald H.
- Silva Diego Augusto Santos
- Silva João Pedro
- Silveira Dayane Gabriele Alves
- Singh Jasvinder A.
- Singh Narinder Pal
- Singh Om Prakash
- Singh Virendra
- Sinha Dhirendra Narain
- Skiadaresi Eirini
- Skirbekk Vegard
- Slepak Erica Leigh
- Smith David L.
- Smith Mari
- Sobaih Badr H. A.
- Sobngwi Eugene
- Soljak Michael
- Sorensen Reed J. D.
- Sousa Tatiane Cristina Moraes
- Sposato Luciano A.
- Sreeramareddy Chandrashekhar T.
- Srinivasan Vinay
- Stanaway Jefrey D.
- Stathopoulou Vasiliki
- Steel Nicholas
- Stein Dan J.
- Steiner Caitlyn
- Steinke Sabine
- Stokes Mark Andrew
- Stovner Lars Jacob
- Strub Bryan
- Subart Michelle
- Sufyan Muawiyyah Babale
- Sunguya Bruno F.
- Sur Patrick J.
- Swaminathan Soumya
- Sykes Bryan L.
- Sylte Dillon
- Szoeke Cassandra E. I.
- Tabarés-Seisdedos Rafael
- Tadakamadla Santosh Kumar
- Tafere Getachew Redae
- Takala Jukka S.
- Tandon Nikhil
- Tanne David
- Tarekegn Yihunie L.
- Tavakkoli Mohammad
- Taveira Nuno
- Taylor Hugh R.
- Tegegne Teketo Kassaw
- Tehrani-Banihashemi Arash
- Tekelab Tesfalidet
- Temam Shifa Girma
- Terkawi Abdullah Sulieman
- Tesfaye Dawit Jember
- Tesssema Belay
- Thakur
- Thamsuwan Ornwipa
- Theadom Alice M.
- Theis Andrew M.
- Thomas Katie E.
- Thomas Nihal
- Thompson Robert
- Thrift Amanda G.
- Tobe-Gai Ruoyan
- Tobollik Myriam
- Tonelli Marcello
- Topor-Madry Roman
- Tortajada Miguel
- Touvier Mathilde
- Traebert Jeferson
- Tran Bach Xuan
- Troeger Christopher
- Truelsen Thomas
- Tsoi Derrick
- Tuzcu Emin Murat
- Tymeson Hayley
- Tyrovolas Stefanos
- Ukwaja Kingsley Nnanna
- Undurraga Eduardo A.
- Uneke Chigozie Jesse
- Updike Rachel
- Uthman Olalekan A.
- Uzochukwu Benjamin S. Chudi
- Van Boven Job F. M.
- Varughese Santosh
- Vasankari Tommi
- Veerman Lennert J.
- Venkatesh
- Venketasubramanian Narayanaswamy
- Vidavalur Ramesh
- Vijayakumar Lakshmi
- Violante Francesco S.
- Vishnu Abhishek
- Vladimirov Sergey K.
- Vlassov Vasiliy Victorovich
- Vollset Stein Emil
- Vos Theo
- Wadilo Fiseha
- Wakayo Tolassa
- Wallin Mitchell T.
- Wang Yuan-Pang
- Weichenthal Scott
- Weiderpass Elisabete
- Weintraub Robert G.
- Weiss Daniel J.
- Werdecker Andrea
- Westerman Ronny
- Whiteford Harvey A.
- Wijeratne Tissa
- Williams Hywel C.
- Wiysonge Charles Shey
- Woldeyes Belete Getahun
- Wolfe Charles D. A.
- Woodbrook Rachel
- Woolf Anthony D.
- Workicho Abdulhalik
- Xavier Denis
- Xu Gelin
- Yadgir Simon
- Yaghoubi Mohsen
- Yakob Bereket
- Yan Lijing L.
- Yano Yuichiro
- Ye Pengpeng
- Yihdego Mahari Gidey
- Yimam Hassen Hamid
- Yip Paul
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z.
- Yu Chuanhua
- Zaidi Zoubida
- Zaki Maysaa El Sayed
- Zegeye Elias Asfaw
- Zenebe Zerihun Menlkalew
- Zhang Xueying
- Zheng Yingfeng
- Zhou Maigeng
- Zipkin Ben
- Zodpey Sanjay
- Zoeckler Leo
- Zuhlke Liesl Joanna
- Ärnlöv Johan
- Publication venue
- Publication date
- 01/01/2017
- Field of study
BACKGROUND: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI).
METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2016. We calculated DALYs by summing years of life lost and years of life lived with disability for each location, age group, sex, and year. We estimated HALE using age-specific death rates and years of life lived with disability per capita. We explored how DALYs and HALE differed from expected trends when compared with the SDI: the geometric mean of income per person, educational attainment in the population older than age 15 years, and total fertility rate.
FINDINGS: The highest globally observed HALE at birth for both women and men was in Singapore, at 75·2 years (95% uncertainty interval 71·9-78·6) for females and 72·0 years (68·8-75·1) for males. The lowest for females was in the Central African Republic (45·6 years [42·0-49·5]) and for males was in Lesotho (41·5 years [39·0-44·0]). From 1990 to 2016, global HALE increased by an average of 6·24 years (5·97-6·48) for both sexes combined. Global HALE increased by 6·04 years (5·74-6·27) for males and 6·49 years (6·08-6·77) for females, whereas HALE at age 65 years increased by 1·78 years (1·61-1·93) for males and 1·96 years (1·69-2·13) for females. Total global DALYs remained largely unchanged from 1990 to 2016 (-2·3% [-5·9 to 0·9]), with decreases in communicable, maternal, neonatal, and nutritional (CMNN) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). The exemplars, calculated as the five lowest ratios of observed to expected age-standardised DALY rates in 2016, were Nicaragua, Costa Rica, the Maldives, Peru, and Israel. The leading three causes of DALYs globally were ischaemic heart disease, cerebrovascular disease, and lower respiratory infections, comprising 16·1% of all DALYs. Total DALYs and age-standardised DALY rates due to most CMNN causes decreased from 1990 to 2016. Conversely, the total DALY burden rose for most NCDs; however, age-standardised DALY rates due to NCDs declined globally.
INTERPRETATION: At a global level, DALYs and HALE continue to show improvements. At the same time, we observe that many populations are facing growing functional health loss. Rising SDI was associated with increases in cumulative years of life lived with disability and decreases in CMNN DALYs offset by increased NCD DALYs. Relative compression of morbidity highlights the importance of continued health interventions, which has changed in most locations in pace with the gross domestic product per person, education, and family planning. The analysis of DALYs and HALE and their relationship to SDI represents a robust framework with which to benchmark location-specific health performance. Country-specific drivers of disease burden, particularly for causes with higher-than-expected DALYs, should inform health policies, health system improvement initiatives, targeted prevention efforts, and development assistance for health, including financial and research investments for all countries, regardless of their level of sociodemographic development. The presence of countries that substantially outperform others suggests the need for increased scrutiny for proven examples of best practices, which can help to extend gains, whereas the presence of underperforming countries suggests the need for devotion of extra attention to health systems that need more robust support.
FUNDING: Bill & Melinda Gates Foundation
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
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- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
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- Ishibashi Akiko
- Ishikawa Sabine K.
- Ishizaki Hinako
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- Jaklevic Michael
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- Jia Jia
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- Nwokenkwo Stanley
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- O\u27Donovan Daniel
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- Okumura Reina
- Okwuonu Geoffrey O.
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- Olivas Jason
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- Olson Maynard V.
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- Perez Agapito
- Perez Lesette M.
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- Sonnhammer Erik
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- Sutherland Grant R.
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- Svatek Amanda F.
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- Tapia Roxanne
- Taring Elizabeth
- Tatsuyama Miho
- Tatum Owatha I.
- Taudien Stefan
- Taylor Amy
- Taylor Christina C.
- Taylor Gillian
- Taylor Kate
- Taylor Ruth
- Taylor Sam
- Taylor Susan
- Taylor Tineace R.
- Taylor Todd Duane
- Tchuinga Pierre
- Tee Louise
- Telford Ethan Brett
- Tenzin Pema
- Terada Yoriko
- Terry Astrid
- Tesfaye Senait
- Tesmer Judith G.
- Tester Julieanne
- Thayer Nina
- Theaker Andrew
- Theil James
- Theodore Joumathe
- Thexton David
- Thies Stephanie
- Thomas Craig
- Thomas Daniel
- Thomas Daryl J.
- Thomas Karen
- Thomas Nicole
- Thomas Paulette
- Thomas Ruth
- Thomas Shereen
- Thommai Roselin
- Thompson Linda S.
- Thorne Rachel Diane
- Thorpe Andrea
- Thorpe Karen
- Thoulutsang Yama
- Threadgold Glen
- Thurston Scott
- Tian Chaoguang
- Tian Chaoguang
- Tian Wei
- Tian Yan
- Tian Yong
- Tian Yuqing
- Tice Hope
- Tighe Damon
- Tin-Wollam Aye M.
- Tinsley Emma
- Tochigi Miwako
- Togashi Naoko
- Tomizawa Iori
- Tomlinson Chad
- Tong Jingli
- Topham Kerri
- Torcaso Bill
- Torney David C.
- Totoki Yasushi
- Towey Sarah
- Toyoda Atsushi
- Tracey Alan
- Tran Ly Thanh
- Tran-Gyamfi Mary
- Trani Lee
- Trankiem Margie
- Trask Barbara J.
- Travers Johnathan
- Trejos Zulma Y.
- Treuhaft Marianne
- Trevino Brenda Kaye
- Tromans Anthony
- Trong Stephan
- Trumbower Heather
- Tsai Ming
- Tsamla Tsamla
- Tsolas Jason
- Tsomo Nawang
- Tsujimoto Susan
- Tsukamoto Yumi
- Tsuruoka Hiromi
- Tsuzuki Rina
- Tu Yuefeng
- Tu Yuefeng
- Tubby Ben
- Tufarelli Cristina
- Turner Heidi
- Turney Kathryn
- Tynan Katherine
- Ueland Stephanie
- Ueng Samantha
- Ukegbu Ogechi Nkemdirim
- Ulanovsky Levy E.
- Un Chun
- Ung Quyen
- Upson Darren
- Urban Jeremy B.
- Ureta-Vidal Abel
- Ureta-Vidal Abel
- Usmani Kamran
- Ustaszewska Anna
- Uyama Nozomi
- Valas Ruben E.
- Valdez Michelle
- Valle Duane
- Valles Yvonne
- Van Brunt Andrew
- Van Dilla Marvin
- Van Helmond Zoe
- Van Luchene Ryan
- Vardanian Zachary
- Vargas Michelle
- Vargo Charles E.
- Vartanian Steffan
- Vasquez Lydia I.
- Vassiliev Helen
- Vastrik Imre
- Vaudin Mark
- Veil Rose
- Veklerov Eugene
- Velasco Nelson
- Velasquez Lisa
- Venkataranan Vijay
- Vera Virginia A.
- Verduzco Daniel
- Vergez Lisa
- Vico Virginie
- Viknaraja Ramya
- Villasana Donna M.
- Vine Wendy
- Viswanathan Vijay
- Vo Andy
- Vo Nu
- Voak Paul
- Vollenhoven David
- Wada Hiromi
- Wagner Mark
- Wagner-McPherson Caryn
- Waldron Lenee
- Waligorski Jason E.
- Walker Davian L.
- Walker Keya
- Walker Sarah
- Wall Melanie
- Wall Randy E.
- Wallace John
- Wallis Justine
- Wallis Michelle
- Walsh Jennifer
- Walsham Natalie
- Wan Ma
- Wang Chunyan
- Wang Dong
- Wang Feng
- Wang Guangxin
- Wang Guihai
- Wang Guihai
- Wang Hongjuan
- Wang Hongwei
- Wang Huanjie
- Wang Huifeng
- Wang Huifeng
- Wang Jian
- Wang Jian
- Wang Jian
- Wang Jie
- Wang Jing
- Wang Jingqiang
- Wang Jingqiang
- Wang Jinhua
- Wang Joann
- Wang Juan
- Wang Jun
- Wang Jun
- Wang Jun
- Wang Li
- Wang Lijie
- Wang Lijuan
- Wang Lijun
- Wang Ling
- Wang Liqun
- Wang Mei
- Wang Qiaoyan
- Wang Shifen
- Wang Shu
- Wang Suzhen
- Wang Wenjun
- Wang Xiaoling
- Wang Xiaoning
- Wang Xuefei
- Wang Xuegang
- Wang Yan
- Wang Yimin
- Wang Ying
- Wang Ying
- Wang Yuanyuan
- Wangchuck Tsering
- Wangdi Tsering
- Ward-Moore Stephanie
- Warren Graham
- Warren James T.
- Warry Georgina
- Watanabe Hidemi
- Watanabe Saki
- Waterston Robert H.
- Watson Andy
- Watt Nicola
- Webb Anthony
- Webb Jeannette
- Webber Caleb
- Weber Ryan J.
- Wehri Edward
- Wei Shulin
- Wei Xuehong
- Weidenbach Richard
- Weinstock George
- Weinstock Keith
- Weir John
- Weissenbach Jean
- Wells Alan
- Wells Sarah
- Welton Robert
- Wen Gaiping
- Wendi Mike
- Weng Li
- Wenning Sarah
- Wentz Sara
- Werler Daniela
- Wesley Mary Melissa
- West Paul
- West Tony
- Wetterstrand Kris
- Wheatley Angela
- Wheatley Carl
- Wheeler David A.
- Wheeler Gideon
- Wheeler Jeremy
- Whitaker Hayley
- White Adam
- White Amelia
- White Brian
- White Catherine
- White Flower
- White Jennifer
- White Johnathon
- White P. Scott
- White Scott P.
- White Simon
- Whitehead Sally
- Whiteley Matthew
- Whitmore Scott
- Whittaker Adam
- Whittaker Charles
- Whittaker Pamela
- Wickremasinghe Manosha I.
- Widaa Sara
- Wiegel Sarah
- Wild Anna
- Wilkinson Jane
- Wilkinson Jane
- Wilkinson Paul
- Willey David
- Williams Albert L.
- Williams Andy
- Williams Bill
- Williams Gabrielle A.
- Williams Leanne
- Williamson Angela L.
- Williamson Helen
- Wills Patricia L.
- Wills Richard
- Wilmer Tamsin
- Wilming Laurens
- Wilson Brian
- Wilson Gareth
- Wilson Margaret
- Wilson Nyree
- Wilson Piers
- Wilson Richard K.
- Wilson Siobhan
- Wilson Steve
- Wilson Wendy
- Wincker Patrick
- Window Philip
- Winster Jenny
- Winzar Claire
- Witt James
- Wleczyk Regina
- Wobus Fred
- Woessner Jeffrey
- Wohldmann Patty
- Wollard Jessica
- Womack Andrew W.
- Wong Benjamin
- Wong Gane K-S
- Wood Diane
- Wood Emma
- Wood Joe
- Wooden Hailey S.
- Wooden Steven H.
- Woodeson Sharon
- Woodfine Kathryn
- Woodmansey Rebecca
- Woods Eric
- Woodwark Cara
- Wooster Richard
- Worley Kim Carlyle
- Woyke Tanja
- Wray Matthew
- Wray Paul
- Wright Charmain
- Wright Debbie
- Wright Kathrine
- Wright Kristin
- Wright Rita A.
- Wu Chungen
- Wu Dongying
- Wu Jiaqian
- Wu Jung-Rung
- Wu Kevin
- Wu Qingfa
- Wu Qingfa
- Wu Ruiming
- Wu Xiao
- Wu Xiaojing
- Wu Zaining
- Wyatt Julia
- Wycoff-Montenegro Melissa
- Wylie Kris
- Wyman Dudley
- Wyman Stacia
- Xi Yan
- Xi Yingying
- Xie Fei
- Xie Gary
- Xie Jane
- Xiong Hui
- Xiong Yuqing
- Xu Alex
- Xu Jing
- Xu Jing
- Xu Ruqin
- Xu Shuhua
- Xu Wei
- Xu Xinlai
- Xu Yan
- Xu Yuning
- Xu Zhihong
- Xu Zuyuan
- Xuan Yali
- Xuan Zhenyu
- Xue Rui
- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
- Yamazaki Satoru
- Yang Hao
- Yang Huanming
- Yang Huanming
- Yang Joan
- Yang Shiaw-Pyng
- Yang Shudong
- Yang Xiaonan
- Yang Xiaonan
- Yang Xiaoping
- Yang Yongkui
- Yano Candance
- Yao Zhijian
- Yao Zhijian
- Yaspo Marie-Laure
- Ye Chen
- Yeager Shane
- Yeh Mimi
- Yen Jennifer
- Yeshitela Rahel Retta
- Yoakum Martin
- Yokobata Kathy
- Yokoyama Jennifer
- Yonezawa Miho
- Yoon Lillienne
- Yoon Vivienne
- Yoshida Satoru
- You Bo
- Young Geneva
- Young Louise
- Young Shelia
- Younger Ruth
- Yu Bing
- Yu Charles
- Yu Fuli
- Yu Jun
- Yu Jun
- Yu Jun
- Yuan Kaiwen
- Yuan Ye
- Yuan Yida
- Yue Shujie
- Yumae Brian
- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
A Possible Alignment Between the Orbits of Planetary Systems and their Visual Binary Companions
- Author
- Abe Lyu
- Agabi Karim
- Amado Pedro J.
- Baker David
- Barkaoui Khalid
- Becker Juliette
- Benkhaldoun Zouhair
- Benni Paul
- Berberian John
- Berlind Perry
- Bieryla Allyson
- Bowen Michael
- Brown Peyton
- Buchhave Lars A.
- Burke Christopher J.
- Buttu Marco
- Cadieux Charles
- Caldwell Douglas A.
- Charbonneau David
- Chazov Nikita
- Chimaladinne Sudhish
- Christian Sam
- Collins Karen A.
- Collins Kevin I.
- Combs Deven
- Conti Dennis M.
- Crouzet Nicolas
- de Beurs Zoe
- de Leon Jerome P.
- Deljookorani Shila
- Diamond Brendan
- Doyon Rene
- Dragomir Diana
- Dransfield Georgina
- Esparza-Borges Emma
- Esquerdo Gilbert A.
- Essack Zahra
- Evans Phil
- Fukui Akihiko
- Gan Tianjun
- Gillon Michael
- Girardin Eric
- Guerra Pere
- Guillot Tristan
- Habich Eleanor Kate K.
- Henriksen Andreea
- Hoch Nora
- Isogai Keisuke I.
- Jehin Emmanuel
- Jenkins Jon M.
- Jensen Eric L. N.
- Johnson Marshall C.
- Kawauchi Kiyoe
- Kielkopf John F.
- Kim Kingsley
- Kraus Adam L.
- Krushinsky Vadim
- Kunzle Veronica
- Laloum Didier
- Latham David W.
- Leger Dominic
- Lewin Pablo
- Livingston John H.
- Lopez Cristina Rodriguez
- Mallia Franco
- Massey Bob
- McLeod Kim K.
- Mekarnia Djamel
- Mireles Ismael
- Mishevskiy Nikolay
- Mori Mayuko
- Murgas Felipe
- Narita Norio
- Naves Ramon
- Nelson Peter
- Osborn Hugh P.
- Palle Enric
- Parviainen Hannu
- Pearce Logan
- Plavchan Peter
- Pozuelos Francisco J.
- Quinn Samuel N.
- Rabus Markus
- Relles Howard M.
- Ricker George R.
- Schlieder Joshua E.
- Schmider Francois-Xavier
- Schwarz Richard P.
- Seager S.
- Shporer Avi
- Sibbald Laurie
- Srdoc Gregor
- Stassun Keivan G.
- Stibbards Caitlin
- Stickler Hannah
- Stockdale Chris
- Suarez Olga
- Tamura Motohide
- Tan Thiam-Guan
- Terada Yuka
- Triaud Amaury
- Tronsgaard Rene
- Vanderburg Andrew
- Vanderspek Roland K.
- Waalkes William C.
- Wang Gavin
- Watanabe Noriharu
- Wenceslas Marie-Sainte
- Wingham Geof
- Winn Joshua N.
- Wittrock Justin
- Yahalomi Daniel A.
- Zhou George
- Ziegler Carl
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/05/2022
- Field of study
Astronomers do not have a complete picture of the effects of wide-binary companions (semimajor axes greater than 100 au) on the formation and evolution of exoplanets. We investigate these effects using new data from Gaia Early Data Release 3 and the Transiting Exoplanet Survey Satellite mission to characterize wide-binary systems with transiting exoplanets. We identify a sample of 67 systems of transiting exoplanet candidates (with well-determined, edge-on orbital inclinations) that reside in wide visual binary systems. We derive limits on orbital parameters for the wide-binary systems and measure the minimum difference in orbital inclination between the binary and planet orbits. We determine that there is statistically significant difference in the inclination distribution of wide-binary systems with transiting planets compared to a control sample, with the probability that the two distributions are the same being 0.0037. This implies that there is an overabundance of planets in binary systems whose orbits are aligned with those of the binary. The overabundance of aligned systems appears to primarily have semimajor axes less than 700 au. We investigate some effects that could cause the alignment and conclude that a torque caused by a misaligned binary companion on the protoplanetary disk is the most promising explanation
Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study
- Author
- Abel K
- Adamali H.
- Adeloye D
- Adeyemi Oluwaseun
- Adrego Rita
- Aguilar Jimenez Laura A.
- Ahmad Haider N
- Ahmad Shanaz
- Ahmed R
- Ahwireng Nyarko
- Ainsworth Mark
- Al-Sheklly B.
- Alamoudi Asma
- Alfaro-Almagro Fidel
- Ali Mariam
- Aljaroof M
- Allan L
- Allen R J
- Allerton Lisa
- Allsop Lynne
- Allt Ann Marie
- Almeida Paula
- Altmann Danny
- Alvarez Corral Maria
- Amoils S.
- Anderson David
- Antoniades C
- Arbane Gill
- Arias Ava Maria
- Armour C.
- Armstrong Lisa
- Armstrong Natalie
- Arnold David
- Arnold H
- Ashish A
- Ashworth Andrew
- Ashworth M
- Aslani S
- Assefa-Kebede Hosanna
- Atkin C
- Atkin Paul
- Aul Raminder
- Aung H
- Austin Liam
- Avram Cristina
- Ayoub A.
- Babores M.
- Baggott R
- Bagshaw J
- Baguley D
- Bailey L
- Baillie J.K.
- Bain S
- Bakali M
- Bakau M
- Baldry E
- Baldwin D
- Baldwin M
- Ballard C
- Bandula Steven
- Banerjee A
- Bang Dongchun
- Barker R E
- Barman L
- Barratt Shaney
- Barrett Fiona
- Basire Donna
- Basu N.
- Bates A
- Bates M
- Batterham R
- Baxendale H
- Bayes Hannah
- Beadsworth M.
- Beckett P
- Beggs Mark
- Begum M
- Beirne Paul
- Bell Murdina
- Bell R
- Bennett Kaytie
- Beranova Eva
- Bermperi Areti
- Berridge Anthony
- Berry C.
- Betts Sarah
- Bevan Emily
- Bhui K
- Bingham Michelle
- Birchall K
- Bishop L.
- Bisnauthsing Karen
- Blaikely J.
- Bloss Angela
- Bolger A.
- Bolton Charlotte E.
- Bonnington J.
- Botkai A
- Bourne Charlotte
- Bourne Michelle
- Bramham K.
- Brear Lucy
- Breen G
- Breeze Jonathon
- Briggs A.
- Bright E
- Brightling Christopher E
- Brill Simon
- Brindle K
- Broad Lauren
- Broadley A
- Brookes C
- Broome M
- Brown Ammani
- Brown Angela
- Brown J.
- Brown Jeremy S
- Brown Jo
- Brown M.
- Brown M.
- Brown V.
- Brugha Terry
- Brunskill Nigel
- Buch M.
- Buckley Phil
- Bularga A.
- Bullmore E
- Bunker Jenny
- Burden L.
- Burdett Tracy
- Burn D.
- Burns A.
- Burns G.
- Busby J.
- Butcher Robyn
- Butt Al-Tahoor
- Byrne S.
- Cairns P
- Calder P C
- Calvelo Ellen
- Carborn H
- Card Bethany
- Carr Caitlin
- Carr Liesel
- Carson G
- Carter Penny
- Casey A
- Cassar Mark P.
- Cavanagh J
- Chablani Manish
- Chalder Trudie
- Chalmers James D.
- Chambers R C
- Chan Flora
- Channon K M
- Chapman Kerry
- Charalambou A
- Chaudhuri N
- Checkley A
- Chen Jin
- Cheng Yutung
- Chetham Luke
- Childs C
- Chilvers Edwin R
- Chinoy H
- Chiribiri Amedeo
- Chong-James K.
- Choudhury Gourab
- Choudhury N.
- Chowienczyk P
- Christie C
- Chrystal Melanie
- Clark Cameron
- Clark D
- Clarke Jude
- Clohisey S.
- Coakley G.
- Coburn Zach
- Coetzee S.
- Cole Joby
- Coleman C
- Conneh Florence
- Connell David
- Connolly B.
- Connor Lynda
- Cook Amanda
- Cooper B
- Cooper J
- Cooper Shirley
- Copeland D.
- Cosier Tracey
- Coulding Martina
- Coupland C.
- Cox Eleanor
- Craig T.
- Crisp P
- Cristiano Daniele
- Crooks M.G.
- Cross Andy
- Cruz Isabel
- Cullinan P.
- Cuthbertson Dan J
- Daines L
- Dalton Matthhew
- Daly Patrick
- Daniels Alison
- Dark P
- Dasgin J
- David A
- David C.
- Davies Ellie
- Davies Ffyon
- Davies Gareth
- Davies Gwyneth A
- Davies Kim
- Davies Melanie J
- Dawson Joy
- Daynes E
- De Soyza Anthony
- Deakin B
- Deans Andrew
- Deas C.
- Deery Joanne
- Defres S.
- Dell Amanda
- Dempsey K.
- Denneny E
- Dennis J
- Dewar A.
- Dharmagunawardena R
- Diar Bakerly Nawar
- Dickens C
- Dipper A.
- Diver Sarah
- Diwanji Shalin N
- Dixon Myles
- Djukanovic R
- Dobson H.
- Dobson S.L.
- Docherty Annemarie B.
- Donaldson A.
- Dong T.
- Dormand N.
- Dougherty Andrew
- Dowling R
- Drain S.
- Draxlbauer K
- Drury Katie
- Dulawan Pearl
- Dunleavy A
- Dunn Sarah
- Dupont Catherine
- Earley Joanne
- Easom Nicholas
- Echevarria Carlos
- Edwards Sarah
- Edwardson C
- El-Taweel Hosni
- Elliott Anne
- Elliott K
- Ellis Y.
- Elmer Anne
- Elneima Omer
- Evans D
- Evans H
- Evans J
- Evans R
- Evans Rachael A
- Evans Ranuromanana I.
- Evans Teriann
- Evenden Cerys
- Evison Lynsey
- Fabbri L
- Fairbairn Sara
- Fairman Alexandra
- Fallon K.
- Faluyi David
- Favager Clair
- Fayzan Tamanah
- Featherstone James
- Felton T.
- Ferreira Vanessa M.
- Finch J
- Finney Selina
- Finnigan J
- Finnigan Lucy
- Fisher Helen
- Fletcher S
- Flockton Rachel
- Flynn Margaret
- Foot H
- Foote David
- Ford Amber
- Forton D
- Fraile Eva
- Francis C.
- Francis R
- Francis Susan
- Frankel A.
- Fraser Emily
- Free Rob
- French N.
- Fu X
- Fuld Jonathan
- Furniss J.
- Garner Lucie
- Gautam N
- Geddes John R.
- George J.
- George P.
- Gibbons M
- Gill Mandy
- Gill Rhyan
- Gilmour L.
- Gleeson Fergus
- Glossop Jodie
- Glover Sarah
- Goodman N
- Goodwin Camelia
- Gooptu Bibek
- Gordon Hussain
- Gorsuch T.
- Greatorex M
- Greenhaff P.L.
- Greenhalf William
- Greenhalgh Alan
- Greening Neil J
- Greenwood John P
- Gregory Heidi
- Gregory Rebecca
- Grieve D.
- Griffin Denise
- Griffiths L
- Guerdette Anne-Marie
- Guillen Guio Beatriz
- Gummadi Mahitha
- Gupta Ayushman
- Gurram Sambasivarao
- Guthrie E
- Guy Z
- Hadley K
- Haggar Ahmed
- Hainey Kera
- Hairsine Brigid
- Haldar Pranab
- Hall I
- Hall Lucy
- Halling-Brown Mark
- Hamil R.
- Hancock Alyson
- Hancock Kia
- Hanley N.A.
- Haq Sulaimaan
- Hardwick H.E.
- Hardy E
- Hardy Tim
- Hargadon Beverley
- Harrington Kate
- Harris Edward
- Harris Victoria C
- Harrison Ewen M.
- Harrison P.
- Hart Nicholas
- Harvey Alice
- Harvey M
- Harvie M
- Haslam L
- Hastie Claire
- Havinden-Williams May
- Hawkes Jenny
- Hawkings Nancy
- Haworth Jill
- Hayday A.
- Haynes Matthew
- Hazeldine J
- Hazelton Tracy
- Heaney Liam G.
- Heeley Cheryl
- Heeney J L
- Heightman M
- Heller S.
- Henderson M
- Henson Helen
- Hesselden L
- Hewitt Melanie
- Highett Victoria
- Hillman T
- Hiwot T
- Ho Ling-Pei
- Hoare Amy
- Hoare Michaela
- Hockridge J
- Hogarth Philip
- Holbourn Ailsa
- Holden S
- Holdsworth L.
- Holgate D
- Holland Maureen
- Holloway Leah
- Holmes Katie
- Holmes Megan
- Holroyd-Hind B
- Holt L
- Hormis Anil
- Horsley Alexander
- Hosseini A.
- Hotopf M
- Houchen-Wolloff Linzy
- Howard K
- Howard Luke S.
- Howell Alice
- Hufton E
- Hughes A D
- Hughes Joan
- Hughes Paul J C
- Hughes Rachel Ann
- Humphries Amy
- Huneke N
- Hurditch E
- Hurst John R
- Husain M
- Hussell T.
- Hutchinson John
- Ibrahim W
- Ilyas F
- Ingham Julie
- Ingram L
- Ionita D
- Isaacs K
- Ismail K.
- Jackson T
- Jacob Joseph
- James W.Y.
- Jang W.
- Jarman Claire
- Jarrold I.
- Jarvis Hannah
- Jastrub Roman
- Jayaraman Bhagy
- Jenkins R Gisli
- Jezzard Peter
- Jiwa Kasim
- Johnson C
- Johnson S
- Johnston D.
- Jolley Caroline J.
- Jones Don
- Jones G.
- Jones H.
- Jones Heather
- Jones I.
- Jones L.
- Jones Mark G
- Jones S.
- Jose Sherly
- Kabir T.
- Kaltsakas G.
- Kamwa V
- Kanellakis N.
- Kaprowska Sabina
- Kausar Zunaira
- Keenan Natalie
- Kelly Matthew
- Kelly S.
- Kemp Graham J
- Kerr Steven
- Kerslake Helen
- Key Angela L.
- Khan F
- Khunti Kamlesh
- Kilroy Susan
- King Bernie
- King Clara
- Kingham L
- Kirk Jill
- Kitterick P
- Klenerman P
- Knibbs Lucy
- Knight Sean
- Knighton Abigail
- Kon Onn M
- Kon S
- Kon Samantha S
- Korszun A.
- Koychev Ivan
- Kurasz Claire
- Kurupati Prathiba
- Laing C
- Lamlum Hanan
- Landers G
- Langenberg C
- Lasserson D
- Lavelle-Langham L.
- Lawrie Allan
- Lawson C
- Lawson Cathy
- Layton Alison
- Lea A
- Leavy Olivia C
- Lee D
- Lee Elvina
- Lee Ju Hee
- Leitch Karen
- Lenagh Rebecca
- Lewis D
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- Zawia Amira
- Zeidan Lisa
- Zhao Bang
- Zheng Bang
- Zongo O.
- Publication venue
- Elsevier
- Publication date
- 22/09/2023
- Field of study
Introduction:
The multiorgan impact of moderate to severe coronavirus infections in the post-acute phase is still poorly understood. We aimed to evaluate the excess burden of multiorgan abnormalities after hospitalisation with COVID-19, evaluate their determinants, and explore associations with patient-related outcome measures.
Methods:
In a prospective, UK-wide, multicentre MRI follow-up study (C-MORE), adults (aged ≥18 years) discharged from hospital following COVID-19 who were included in Tier 2 of the Post-hospitalisation COVID-19 study (PHOSP-COVID) and contemporary controls with no evidence of previous COVID-19 (SARS-CoV-2 nucleocapsid antibody negative) underwent multiorgan MRI (lungs, heart, brain, liver, and kidneys) with quantitative and qualitative assessment of images and clinical adjudication when relevant. Individuals with end-stage renal failure or contraindications to MRI were excluded. Participants also underwent detailed recording of symptoms, and physiological and biochemical tests. The primary outcome was the excess burden of multiorgan abnormalities (two or more organs) relative to controls, with further adjustments for potential confounders. The C-MORE study is ongoing and is registered with ClinicalTrials.gov, NCT04510025.
Findings:
Of 2710 participants in Tier 2 of PHOSP-COVID, 531 were recruited across 13 UK-wide C-MORE sites. After exclusions, 259 C-MORE patients (mean age 57 years [SD 12]; 158 [61%] male and 101 [39%] female) who were discharged from hospital with PCR-confirmed or clinically diagnosed COVID-19 between March 1, 2020, and Nov 1, 2021, and 52 non-COVID-19 controls from the community (mean age 49 years [SD 14]; 30 [58%] male and 22 [42%] female) were included in the analysis. Patients were assessed at a median of 5·0 months (IQR 4·2–6·3) after hospital discharge. Compared with non-COVID-19 controls, patients were older, living with more obesity, and had more comorbidities. Multiorgan abnormalities on MRI were more frequent in patients than in controls (157 [61%] of 259 vs 14 [27%] of 52; p<0·0001) and independently associated with COVID-19 status (odds ratio [OR] 2·9 [95% CI 1·5–5·8]; padjusted=0·0023) after adjusting for relevant confounders. Compared with controls, patients were more likely to have MRI evidence of lung abnormalities (p=0·0001; parenchymal abnormalities), brain abnormalities (p<0·0001; more white matter hyperintensities and regional brain volume reduction), and kidney abnormalities (p=0·014; lower medullary T1 and loss of corticomedullary differentiation), whereas cardiac and liver MRI abnormalities were similar between patients and controls. Patients with multiorgan abnormalities were older (difference in mean age 7 years [95% CI 4–10]; mean age of 59·8 years [SD 11·7] with multiorgan abnormalities vs mean age of 52·8 years [11·9] without multiorgan abnormalities; p<0·0001), more likely to have three or more comorbidities (OR 2·47 [1·32–4·82]; padjusted=0·0059), and more likely to have a more severe acute infection (acute CRP >5mg/L, OR 3·55 [1·23–11·88]; padjusted=0·025) than those without multiorgan abnormalities. Presence of lung MRI abnormalities was associated with a two-fold higher risk of chest tightness, and multiorgan MRI abnormalities were associated with severe and very severe persistent physical and mental health impairment (PHOSP-COVID symptom clusters) after hospitalisation.
Interpretation:
After hospitalisation for COVID-19, people are at risk of multiorgan abnormalities in the medium term. Our findings emphasise the need for proactive multidisciplinary care pathways, with the potential for imaging to guide surveillance frequency and therapeutic stratification
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015
- Author
- Aasvang Gunn Marit
- Abajobir Amanuel Alemu
- Abate Kalkidan Hassen
- Abbafati Cristiana
- Abbas Kaja M.
- Abd-Allah Foad
- Abdulle Abdishakur M.
- Abera Semaw Ferede
- Abraham Biju
- Abu-Raddad Laith J.
- Abyu Gebre Yitayih
- Adebiyi Akindele Olupelumi
- Adedeji Isaac Akinkunmi
- Ademi Zanfina
- Adou Arsene Kouablan
- Adsuar Jose C.
- Afshin Ashkan
- Agardh Emilie Elisabet
- Agarwal Arnav
- Agrawal Anurag
- Ahmad Kiadaliri Aliasghar
- Ajala Oluremi N.
- Akinyemiju Tomi F.
- Al-Aly Ziyad
- Alam Khurshid
- Alam Noore K. M.
- Aldhahri Saleh Fahed
- Aldridge Robert William
- Alemu Zewdie Aderaw
- Alexander Lily T.
- Ali Raghib
- Alkerwi Ala’a
- Alla Francois
- Allebeck Peter
- Alsharif Ubai
- Altirkawi Khalid A.
- Alvarez Martin Elena
- Alvis-Guzman Nelson
- Amare Azmeraw T.
- Amberbir Alemayehu
- Amegah Adeladza Kofi
- Amini Heresh
- Ammar Walid
- Amrock Stephen Marc
- Andersen Hjalte H.
- Anderson Benjamin O.
- Anderson H. Ross
- Antonio Carl Abelardo T.
- Anwari Palwasha
- Arnlov Johan
- Artaman Al
- Asayesh Hamid
- Asghar Rana Jawad
- Assadi Reza
- Atique Suleman
- Avokpaho Euripide Frinel G. Arthur
- Awasthi Ashish
- Ayala Quintanilla Beatriz Paulina
- Azzopardi Peter
- Bacha Umar
- Badawi Alaa
- Bahit Maria C.
- Balakrishnan Kalpana
- Barac Aleksandra
- Barber Ryan M.
- Barker-Collo Suzanne L.
- Barnighausen Till
- Barquera Simon
- Barregard Lars
- Barrero Lope H.
- Basu Sanjay
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- Bedi Neeraj
- Beghi Ettore
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- Bhutta Zulfiqar A.
- Biadgilign Sibhatu
- Bikbov Boris
- Biryukov Stan
- Bisanzio Donal
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- Blore Jed D.
- Borschmann Rohan
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- Brainin Michael
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- Casey Daniel C.
- Castaneda-Orjuela Carlos A.
- Castillo Rivas Jacqueline
- Castro Ruben Estanislao
- Catala-Lopez Ferran
- Cercy Kelly
- Chang Jung-Chen
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- Chibalabala Mirriam
- Chimed-Ochir Odgerel
- Chisumpa Vesper Hichilombwe
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- Christensen Hanne
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- Contreras Manzano Alejandra G.
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- Endries Aman Yesuf
- Ermakov Sergey Petrovich
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- Esteghamati Alireza
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- Harb Hilda L.
- Harikrishnan Sivadasanpillai
- Haro Josep Maria
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- Jayaraman Sudha P.
- Jayatilleke Achala Upendra
- Jee Sun Ha
- Jeemon Panniyammakal
- Jha Vivekanand
- Jiang Ying
- Jibat Tariku
- Jin Ye
- Johnson Catherine O.
- Jonas Jost B.
- Kabir Zubair
- Kalkonde Yogeshwar
- Kamal Ritul
- Kan Haidong
- Karch Andre
- Karema Corine Kakizi
- Karimkhani Chante
- Kasaeian Amir
- Kaul Anil
- Kawakami Norito
- Kazi Dhruv S.
- Keiyoro Peter Njenga
- Kemmer Laura
- Kemp Andrew Haddon
- Kengne Andre Pascal
- Keren Andre
- Kesavachandran Chandrasekharan Nair
- Khader Yousef Saleh
- Khan Abdur Rahman
- Khan Ejaz Ahmad
- Khan Gulfaraz
- Khang Young-Ho
- Khatibzadeh Shahab
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- Kissoon Niranjan
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- Knibbs Luke D.
- Kokubo Yoshihiro
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- Kravchenko Michael
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- Resnikoff Serge
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- Shaddick Gavin
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- Sharma Rajesh
- She Jun
- Sheikhbahaei Sara
- Shen Jiabin
- Sheth Kevin N.
- Shi Peilin
- Shibuya Kenji
- Shigematsu Mika
- Shin Min-Jeong
- Shiri Rahman
- Shishani Kawkab
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- Sigfusdottir Inga Dora
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- Silveira Dayane Gabriele Alves
- Silverberg Jonathan I.
- Simard Edgar P.
- Sindi Shireen
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- Singh Prashant Kumar
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- Soljak Michael
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- Stathopoulou Vasiliki
- Steckling Nadine
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- Stockl Heidi
- Stranges Saverio
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- Sunguya Bruno F.
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- Swaminathan Soumya
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- Szoeke Cassandra E. I.
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- Tedla Bemnet Amare
- Tefera Worku Mekonnen
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- Towbin Jeffrey Allen
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- Tsilimparis Nikolaos
- Tura Abera Kenay
- Tuzcu Emin Murat
- Tyrovolas Stefanos
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- Undurraga Eduardo A.
- Uneke Chigozie Jesse
- Uthman Olalekan A.
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- Varakin Yuri Y.
- Vasankari Tommi
- Veerman J. Lennert
- Venketasubramanian Narayanaswamy
- Violante Francesco S.
- Vollset Stein Emil
- Vos Theo
- Wagner Gregory R.
- Wagner Joseph A.
- Waller Stephen G.
- Wang Haidong
- Wang Jian Li
- Wang Linhong
- Wang Yanping
- Weichenthal Scott
- Weiderpass Elisabete
- Weintraub Robert G.
- Werdecker Andrea
- Westerman Ronny
- Whiteford Harvey A.
- Wijeratne Tissa
- Wiysonge Charles Shey
- Wolfe Charles D. A.
- Won Sungho
- Woolf Anthony D.
- Wubshet Mamo
- Xavier Denis
- Xu Gelin
- Yadav Ajit Kumar
- Yakob Bereket
- Yalew Ayalnesh Zemene
- Yano Yuichiro
- Yaseri Mehdi
- Ye Pengpeng
- Yip Paul
- Yonemoto Naohiro
- Yoon Seok-Jun
- Younis Mustafa Z.
- Yu Chuanhua
- Zaidi Zoubida
- Zaki Maysaa El Sayed
- Zhao Yi
- Zhou Maigeng
- Zhu Jun
- Zipkin Ben
- Zodpey Sanjay
- Zuhlke Liesl Joanna
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2016
- Field of study
Forouzanfar MH, Afshin A, Alexander LT, et al. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. LANCET. 2016;388(10053):1659-1724.Background The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debates on the importance of addressing risks in context. Methods We used the comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study to estimate attributable deaths, disability-adjusted life-years (DALYs), and trends in exposure by age group, sex, year, and geography for 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks from 1990 to 2015. This study included 388 risk-outcome pairs that met World Cancer Research Fund-defined criteria for convincing or probable evidence. We extracted relative risk and exposure estimates from randomised controlled trials, cohorts, pooled cohorts, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. We developed a metric that allows comparisons of exposure across risk factors-the summary exposure value. Using the counterfactual scenario of theoretical minimum risk level, we estimated the portion of deaths and DALYs that could be attributed to a given risk. We decomposed trends in attributable burden into contributions from population growth, population age structure, risk exposure, and risk-deleted cause-specific DALY rates. We characterised risk exposure in relation to a Socio-demographic Index (SDI). Findings Between 1990 and 2015, global exposure to unsafe sanitation, household air pollution, childhood underweight, childhood stunting, and smoking each decreased by more than 25%. Global exposure for several occupational risks, high body-mass index (BMI), and drug use increased by more than 25% over the same period. All risks jointly evaluated in 2015 accounted for 57.8% (95% CI 56.6-58.8) of global deaths and 41.2% (39.8-42.8) of DALYs. In 2015, the ten largest contributors to global DALYs among Level 3 risks were high systolic blood pressure (211.8 million [192.7 million to 231.1 million] global DALYs), smoking (148.6 million [134.2 million to 163.1 million]), high fasting plasma glucose (143.1 million [125.1 million to 163.5 million]), high BMI (120.1 million [83.8 million to 158.4 million]), childhood undernutrition (113.3 million [103.9 million to 123.4 million]), ambient particulate matter (103.1 million [90.8 million to 115.1 million]), high total cholesterol (88.7 million [74.6 million to 105.7 million]), household air pollution (85.6 million [66.7 million to 106.1 million]), alcohol use (85.0 million [77.2 million to 93.0 million]), and diets high in sodium (83.0 million [49.3 million to 127.5 million]). From 1990 to 2015, attributable DALYs declined for micronutrient deficiencies, childhood undernutrition, unsafe sanitation and water, and household air pollution; reductions in risk-deleted DALY rates rather than reductions in exposure drove these declines. Rising exposure contributed to notable increases in attributable DALYs from high BMI, high fasting plasma glucose, occupational carcinogens, and drug use. Environmental risks and childhood undernutrition declined steadily with SDI; low physical activity, high BMI, and high fasting plasma glucose increased with SDI. In 119 countries, metabolic risks, such as high BMI and fasting plasma glucose, contributed the most attributable DALYs in 2015. Regionally, smoking still ranked among the leading five risk factors for attributable DALYs in 109 countries; childhood underweight and unsafe sex remained primary drivers of early death and disability in much of sub-Saharan Africa. Interpretation Declines in some key environmental risks have contributed to declines in critical infectious diseases. Some risks appear to be invariant to SDI. Increasing risks, including high BMI, high fasting plasma glucose, drug use, and some occupational exposures, contribute to rising burden from some conditions, but also provide opportunities for intervention. Some highly preventable risks, such as smoking, remain major causes of attributable DALYs, even as exposure is declining. Public policy makers need to pay attention to the risks that are increasingly major contributors to global burden. Copyright (C) The Author(s). Published by Elsevier Ltd
Measurements of top-quark pair differential cross-sections in the eμ channel in pp collisions at s=13 TeV using the ATLAS detector
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- Aad Georges
- Abbott Brad
- Abdallah Jalal
- Abdinov Ovsat
- Abeloos Baptiste
- Aben Rosemarie
- AbouZeid Ossama
- Abraham Nicola
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Sami
- Adachi Shunsuke
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Affolder Tony
- Agatonovic-Jovin Tatjana
- Aguilar-Saavedra Juan Anton
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Jose
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Ali Babar
- Aliev Malik
- Alimonti Gianluca
- Alison John
- Alkire Steven Pat
- Allbrooke Benedict
- Allen Benjamin W
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Alshehri Azzah Aziz
- Alstaty Mahmoud
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazi
- Amadio Brian Thom
- Amako Katsuya
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Pat
- Amorim Antonio
- Amoroso Simone
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Ste
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders Gabriel
- Anders John Kenne
- Anderson Kelby
- Andreazza Attilio
- Andrei George Vic
- Angelidakis Stylianos
- Angelozzi Ivan
- Angerami Aaron
- Anghinolfi Francis
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antel Claire
- Antonelli Mario
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- Aoki Masato
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- Wosiek Barbara
- Wotschack Jorg
- Woudstra Martin
- Wozniak Krzysztof
- Wu Mengqing
- Wu Miles
- Wu Sau Lan
- Wu Xin
- Wu Yusheng
- Wyatt Terry Rich
- Wynne Benjamin
- Xella Stefania
- Xu Da
- Xu Lailin
- Yabsley Bruce
- Yacoob Sahal
- Yamaguchi Daiki
- Yamaguchi Yohei
- Yamamoto Akira
- Yamamoto Shimpei
- Yamanaka Takashi
- Yamauchi Katsuya
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
- Yang Hongtao
- Yang Yi
- Yang Zongchang
- Yao Weiming
- Yap Yee Chinn
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven Henr
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yildirim Eda
- Yorita Kohei
- Yoshida Rikutaro
- Yoshihara Keisuke
- Young Charles
- Young Christophe
- Youssef Saul
- Yu David Ren-
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zakharchuk Nataliia
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zeng Jian Cong
- Zeng Qi
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Matt
- Zhang Rui
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Mingliang
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zwalinski Lukasz
- Åkesson Torsten Pa
- Åsman Barbro
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 08/05/2017
- Field of study
- …